Beth Pflug

  • 1747 Citations
  • 25 h-Index
19912016

Research output per year

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Publications

  • 1747 Citations
  • 25 h-Index
  • 35 Article
  • 1 Conference contribution
  • 1 Review article
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Article
2016

Metabolic and molecular regulation of dietary polyunsaturated fatty acids on prostate cancer

Zhao, H., Pflug, B., Lai, X. & Wang, M., Mar 1 2016, In : Proteomics - Clinical Applications. 10, 3, p. 267-279 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pyruvate dehydrogenase alpha 1 as a target of omega-3 polyunsaturated fatty acids in human prostate cancer through a global phosphoproteomic analysis

Zhao, H., Pflug, B., Lai, X. & Wang, M., Sep 1 2016, In : Proteomics. 16, 17, p. 2419-2431 13 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Repositioning proton pump inhibitors as anticancer drugs by targeting the thioesterase domain of human fatty acid synthase

Fako, V. E., Wu, X., Pflug, B., Liu, J. Y. & Zhang, J. T., Jan 22 2015, In : Journal of Medicinal Chemistry. 58, 2, p. 778-784 7 p.

Research output: Contribution to journalArticle

25 Scopus citations
2010

Pregnane X receptor as a therapeutic target to inhibit androgen activity

Zhang, B., Cheng, Q., Ou, Z., Lee, J. H., Xu, M., Kochhar, U., Ren, S., Huang, M., Pflug, B. R. & Xie, W., Dec 2010, In : Endocrinology. 151, 12, p. 5721-5729 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
2009

Translocator protein blockade reduces prostate tumor growth

Fafalios, A., Akhavan, A., Parwani, A. V., Bies, R. R., McHugh, K. J. & Pflug, B. R., Oct 1 2009, In : Clinical Cancer Research. 15, 19, p. 6177-6184 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
2008
2 Scopus citations

Longitudinal analysis of androgen deprivation of prostate cancer cells identifies pathways to androgen independence

D'Antonio, J. M., Ma, C., Monzon, F. A. & Pflug, B. R., May 15 2008, In : Prostate. 68, 7, p. 698-714 17 p.

Research output: Contribution to journalArticle

26 Scopus citations

Therapeutic Effects of Endothelin-A Receptor Antagonist on Bladder Overactivity in Rats with Chronic Spinal Cord Injury

Ogawa, T., Sasatomi, K., Hiragata, S., Seki, S., Nishizawa, O., Chermansky, C. J., Pflug, B. R., Nelson, J. B., Chancellor, M. B. & Yoshimura, N., Feb 2008, In : Urology. 71, 2, p. 341-345 5 p.

Research output: Contribution to journalArticle

10 Scopus citations
2007

Distinct Patterns of Endothelin Axis Expression in Primary Prostate Cancer

Godara, G., Pecher, S., Jukic, D. M., D'Antonio, J. M., Akhavan, A., Nelson, J. B. & Pflug, B. R., Jul 1 2007, In : Urology. 70, 1, p. 209-215 7 p.

Research output: Contribution to journalArticle

18 Scopus citations

Endothelin-1 promotes cell survival in renal cell carcinoma through the ETA receptor

Pflug, B. R., Zheng, H., Udan, M. S., D'Antonio, J. M., Marshall, F. F., Brooks, J. D. & Nelson, J. B., Feb 8 2007, In : Cancer Letters. 246, 1-2, p. 139-148 10 p.

Research output: Contribution to journalArticle

46 Scopus citations
2006

Endothelin receptor A blockade enhances taxane effects in prostate cancer

Akhavan, A., McHugh, K. H., Guruli, G., Bies, R. R., Zamboni, W. C., Strychor, S., Nelson, J. B. & Pflug, B. R., Jan 1 2006, In : Neoplasia. 8, 9, p. 725-732 8 p.

Research output: Contribution to journalArticle

43 Scopus citations

Fatty acid synthase gene overexpression and copy number gain in prostate adenocarcinoma

Shah, U. S., Dhir, R., Gollin, S. M., Chandran, U. R., Lewis, D., Acquafondata, M. & Pflug, B. R., Apr 1 2006, In : Human pathology. 37, 4, p. 401-409 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
2005

Endothelin-1 inhibits apoptosis in prostate cancer

Nelson, J. B., Udan, M. S., Guruli, G. & Pflug, B. R., Jul 2005, In : Neoplasia. 7, 7, p. 631-637 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Role of endothelin axis in progression to aggressive phenotype of prostate adenocarcinoma

Godara, G., Cannon, G. W., Cannon, G. M., Bies, R. R., Nelson, J. B. & Pflug, B. R., Sep 15 2005, In : Prostate. 65, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

31 Scopus citations
2004

Differential roles of peripheral and spinal endothelin receptors in the micturition reflex in rats

Ogawa, T., Kamo, I., Pflug, B. R., Nelson, J. B., Seki, S., Igawa, Y., Nishizawa, O., De Groat, W. C., Chancellor, M. B. & Yoshimura, N., Oct 2004, In : Journal of Urology. 172, 4 I, p. 1533-1537 5 p.

Research output: Contribution to journalArticle

21 Scopus citations

Endothelin A receptor blockade does not alter PSA secretion in prostate cancer cell lines

Pecher, S., Pflug, B. R., Brink, A. K. W. & Nelson, J. B., Aug 1 2004, In : Prostate. 60, 3, p. 175-177 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Function and survival of dendritic cells depend on endothelin-1 and endothelin receptor autocrine loops

Guruli, G., Pflug, B. R., Pecher, S., Makarenkova, V., Shurin, M. R. & Nelson, J. B., Oct 1 2004, In : Blood. 104, 7, p. 2107-2115 9 p.

Research output: Contribution to journalArticle

47 Scopus citations
2003

Increased Fatty Acid Synthase Expression and Activity During Progression of Prostate Cancer in the TRAMP Model

Pflug, B. R., Pecher, S. M., Brink, A. W., Nelson, J. B. & Foster, B. A., Nov 1 2003, In : Prostate. 57, 3, p. 245-254 10 p.

Research output: Contribution to journalArticle

45 Scopus citations
2002

Stat3 enhances the growth of LNCaP human prostate cancer cells in intact and castrated male nude mice

DeMiguel, F., Lee, S. O., Lou, W., Xiao, X., Pflug, B. R., Nelson, J. B. & Gao, A. C., Jun 1 2002, In : Prostate. 52, 2, p. 123-129 7 p.

Research output: Contribution to journalArticle

39 Scopus citations
2001

Detection of increased choline compounds with proton nuclear magnetic resonance spectroscopy subsequent to malignant transformation of human prostatic epithelial cells

Ackerstaff, E., Pflug, B. R., Nelson, J. B. & Bhujwalla, Z. M., May 1 2001, In : Cancer Research. 61, 9, p. 3599-3603 5 p.

Research output: Contribution to journalArticle

248 Scopus citations

Dexamethasone reduces the expression of p75 neurotrophin receptor and apoptosis in contused spinal cord

Brandoli, C., Shi, B., Pflug, B., Andrews, P., Wrathall, J. R. & Mocchetti, I., Feb 19 2001, In : Molecular Brain Research. 87, 1, p. 61-70 10 p.

Research output: Contribution to journalArticle

26 Scopus citations

Increased fatty acid synthase as a therapeutic target in androgen-independent prostate cancer progression

Pizer, E. S., Pflug, B. R., Steven Bova, G., Han, W. F., Udan, M. S. & Nelson, J. B., May 1 2001, In : Prostate. 47, 2, p. 102-110 9 p.

Research output: Contribution to journalArticle

133 Scopus citations

TrkA induces differentiation but not apoptosis in C6-2B glioma cells

Pflug, B. R., Colangelo, A. M., Tornatore, C. & Mocchetti, I., Jun 15 2001, In : Journal of Neuroscience Research. 64, 6, p. 636-645 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
1999

Caveolin expression is decreased following androgen deprivation in human prostate cancer cell lines

Pflug, B. R., Reiter, R. E. & Nelson, J. B., 1999, In : Prostate. 40, 4, p. 269-273 5 p.

Research output: Contribution to journalArticle

47 Scopus citations
1998
51 Scopus citations
1997

Loss of low-affinity nerve growth factor receptor during malignant transformation of the human prostate

Perez, M., Regan, T., Pflug, B., Lynch, J. & Djakiew, D., Mar 1 1997, In : Prostate. 30, 4, p. 274-279 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Two peptides derived from the nerve growth factor precursor are biologically active

Dicou, E., Pflug, B., Magazin, M., Lehy, T., Djakiew, D., Ferrara, P., Nerrière, V. & Harvie, D., 1997, In : Journal of Cell Biology. 136, 2, p. 389-398 10 p.

Research output: Contribution to journalArticle

27 Scopus citations
1995

Expression of a trk high affinity nerve growth factor receptor in the human prostate

Pflug, B. R., Dionne, C., Kaplan, D. R., Lynch, J. & Djakiew, D., Jan 1995, In : Endocrinology. 136, 1, p. 262-268 7 p.

Research output: Contribution to journalArticle

95 Scopus citations
11 Scopus citations
1994

Postnatal expression of nerve growth factor receptors in the rat testis

Djakiew, D., Pflug, B., Dionne, C. & Onoda, M., 1994, In : Biology of reproduction. 51, 2, p. 214-221 8 p.

Research output: Contribution to journalArticle

40 Scopus citations
1993

Chemotaxis and Chemokinesis of Human Prostate Tumor Cell Lines in Response to Human Prostate Stromal Cell Secretory Proteins Containing a Nerve Growth Factor-like Protein1

Djakiew, D., Pflug, B. R., Delsite, R., Onoda, M. & Thompson, E. W., Mar 1993, In : Cancer Research. 53, 6, p. 1416-1420 5 p.

Research output: Contribution to journalArticle

61 Scopus citations
1992

Density dependent polarized secretion of a prostatic epithelial cell line

Djakiew, D., Pflug, B., Delsite, R., Lynch, J. H. & Onoda, M., 1992, In : The Prostate. 20, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

6 Scopus citations
105 Scopus citations
1991

Germ cell mitogenic activity is associated with nerve growth factor‐like protein(s)

Onoda, M., Pflug, B. & Djakiew, D., Dec 1991, In : Journal of cellular physiology. 149, 3, p. 536-543 8 p.

Research output: Contribution to journalArticle

27 Scopus citations

Regulation of Growth by a Nerve Growth Factor-like Protein Which Modulates Paracrine Interactions between a Neoplastic Epithelial Cell Line and Stromal Cells of the Human Prostate

Djakiew, D., Delsite, R., Pflug, B., Wrathall, J. & Onoda, M., Jun 1991, In : Cancer Research. 51, 12, p. 3304-3310 7 p.

Research output: Contribution to journalArticle

123 Scopus citations