Bruce Molitoris

  • 15900 Citations
  • 62 h-Index
1974 …2020

Research output per year

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Publications

1993

Disease processes in epithelia: the role of the actin cytoskeleton and altered surface membrane polarity

Leiser, J. & Molitoris, B. A., Nov 25 1993, In : BBA - Molecular Basis of Disease. 1225, 1, p. 1-13 13 p.

Research output: Contribution to journalReview article

39 Scopus citations

Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells

Molitoris, B. A., Meyer, C., Dahl, R. & Geerdes, A., Jan 1 1993, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 264, 5 33-5, p. F907-F916

Research output: Contribution to journalArticle

32 Scopus citations
61 Scopus citations
1994

Alterations in epithelial polarity and the pathogenesis of disease states

Epstein, F. H., Fish, E. M. & Molitoris, B. A., Jun 2 1994, In : New England Journal of Medicine. 330, 22, p. 1580-1588 9 p.

Research output: Contribution to journalReview article

180 Scopus citations

Apically and basolaterally internalized aminoglycosides colocalize in LLC- PK1 lysosomes and alter cell function

Ford, D. M., Dahl, R. H., Lamp, C. A. & Molitoris, B. A., Jan 1 1994, In : American Journal of Physiology - Cell Physiology. 266, 1 35-1, p. C52-C57

Research output: Contribution to journalArticle

23 Scopus citations

Characterization of the beta2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B., 1994, In : The American journal of physiology. 267, 3 part 2

Research output: Contribution to journalArticle

Characterization of the β2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B. A., Jan 1 1994, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 267, 3 36-3, p. F380-F389

Research output: Contribution to journalArticle

22 Scopus citations
30 Scopus citations

Inherited Diseases of the Glomerular Basement Membrane

Bodziak, K. A., Hammond, W. S. & Molitoris, B. A., Jan 1 1994, In : American Journal of Kidney Diseases. 23, 4, p. 605-618 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Membrane adsorption of β2-microglobulin: Equilibrium and kinetic characterization

Clark, W. R., Macias, W. L., Molitoris, B. A. & Wang, N. H. L., Oct 1994, In : Kidney international. 46, 4, p. 1140-1146 7 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations
1995

Convergence of apical and basolateral endocytic pathways for β2- microglobulin in LLC-PK1 cells

Cohen, M., Sundin, D. P., Dahl, R. & Molitoris, B. A., Jan 1 1995, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268, 5 37-5, p. F829-F838

Research output: Contribution to journalArticle

10 Scopus citations

HWA-448 reduces gentamicin toxicity in LLC-PK1 cells

Ford, D. M., Thieme, R. E., Lamp, C. A., Covington, S. J. & Molitoris, B. A., Jan 1 1995, In : Journal of Pharmacology and Experimental Therapeutics. 274, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Plasma protein adsorption to highly permeable hemodialysis membranes

Clark, W. R., Macias, W. L., Molitoris, B. A. & Wang, N. H. L., Aug 1995, In : Kidney international. 48, 2, p. 481-488 8 p.

Research output: Contribution to journalArticle

Open Access
65 Scopus citations
1996

Cellular ATP depletion induces disruption of the spectrin cytoskeletal network

Molitoris, B. A., Dahl, R. & Hosford, M., Dec 1 1996, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 271, 4 40-4, p. F790-F798

Research output: Contribution to journalArticle

55 Scopus citations

Recovery of the actin cytoskeleton during cellular repair is independent of protein synthesis

Hosford, M., Sandoval, R. & Molitoris, B. A., Jan 1 1996, In : Journal of Investigative Medicine. 44, 1, p. 169A

Research output: Contribution to journalArticle

Surface membrane polarity of proximal tubular cells: Alterations as a basis for malfunction

Molitoris, B. A. & Wagner, M. C., Jan 1 1996, In : Kidney international. 49, 6, p. 1592-1597 6 p.

Research output: Contribution to journalArticle

Open Access
31 Scopus citations
1997

Acute renal failure in the 21st century: Recommendations for management and outcomes assessment

DuBose, T. D., Warnock, D. G., Mehta, R. L., Bonventre, J. V., Hammerman, M. R., Molitoris, B. A., Paller, M. S., Siegel, N. J., Scherbenske, J. & Striker, G. E., May 1997, In : American Journal of Kidney Diseases. 29, 5, p. 793-799 7 p.

Research output: Contribution to journalArticle

88 Scopus citations

ATP depletion alters myosin Iβ cellular location in LLC-PK1 cells

Wagner, M. C. & Molitoris, B. A., Jun 26 1997, In : American Journal of Physiology - Cell Physiology. 272, 5 41-5, p. C1680-C1690

Research output: Contribution to journalArticle

29 Scopus citations

Cell biology of aminoglycoside nephrotoxicity: Newer aspects

Molitoris, B. A., Jan 1 1997, In : Current Opinion in Nephrology and Hypertension. 6, 4, p. 384-388 5 p.

Research output: Contribution to journalReview article

24 Scopus citations

Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment

Sundin, D. P., Meyer, C., Dahl, R., Geerdes, A., Sandoval, R. & Molitoris, B. A., May 21 1997, In : American Journal of Physiology - Cell Physiology. 272, 4 41-4, p. C1309-C1318

Research output: Contribution to journalArticle

21 Scopus citations

Putting the actin cytoskeleton into perspective: Pathophysiology of ischemic alterations

Molitoris, B. A., Apr 1 1997, In : American Journal of Physiology - Renal Physiology. 272, 4 41-4, p. F430-F433

Research output: Contribution to journalReview article

74 Scopus citations

Putting the actin cytoskeleton into perspective: Pathophysiology of ischemie alterations

Molitoris, B. A., Dec 1 1997, In : American Journal of Physiology. 272, 4 PART 2, p. F434-F442

Research output: Contribution to journalArticle

14 Scopus citations

Role of the actin cytoskeleton in ischemia-induced cell injury and repair

Molitoris, B. A., Leiser, J. & Wagner, M. C., Dec 1 1997, In : Pediatric Nephrology. 11, 6, p. 761-767 7 p.

Research output: Contribution to journalArticle

47 Scopus citations
1998

Aminoglycoside antibiotics traffic to the Golgi complex in LLC-PK1 cells

Sandoval, R., Leiser, J. & Molitoris, B. A., Feb 1 1998, In : Journal of the American Society of Nephrology. 9, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Ischemic acute renal failure: Exciting times at our fingertips

Molitoris, B. A., Aug 3 1998, In : Current Opinion in Nephrology and Hypertension. 7, 4, p. 405-406 2 p.

Research output: Contribution to journalEditorial

18 Scopus citations

Mechanisms of cellular injury in ischemic acute renal failure

Sutton, T. A. & Molitoris, B. A., Sep 30 1998, In : Seminars in nephrology. 18, 5, p. 490-497 8 p.

Research output: Contribution to journalReview article

137 Scopus citations
1999

Acute renal failure

Molitoris, B. A., Sep 1 1999, In : Drugs of Today. 35, 9, p. 659-666 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

Ischemia activates actin depolymerizing factor: Role in proximal tubule microvillar actin alterations

Schwartz, N., Hosford, M., Sandoval, R. M., Wagner, M. C., Atkinson, S. J., Bamburg, J. & Molitoris, B. A., Apr 1 1999, In : American Journal of Physiology - Renal Physiology. 276, 4 45-4, p. F544-F551

Research output: Contribution to journalArticle

79 Scopus citations

Pathophysiology and functional significance of apical membrane disruption during ischemia

Ashworth, S. L. & Molitoris, B. A., Dec 1 1999, In : Current Opinion in Nephrology and Hypertension. 8, 4, p. 449-458 10 p.

Research output: Contribution to journalReview article

30 Scopus citations

Renal epithelial polarity in health and disease

Wagner, M. C. & Molitoris, B. A., Feb 1 1999, In : Pediatric Nephrology. 13, 2, p. 163-170 8 p.

Research output: Contribution to journalReview article

30 Scopus citations

The role of cell adhesion molecules in ischemic acute renal failure

Molitoris, B. A. & Marrs, J., May 1999, In : American Journal of Medicine. 106, 5, p. 583-592 10 p.

Research output: Contribution to journalArticle

110 Scopus citations
2000

Acute renal failure in the new millennium: Time to consider combination therapy

Kelly, K. J. & Molitoris, B. A., Jan 26 2000, In : Seminars in Nephrology. 20, 1, p. 4-19 16 p.

Research output: Contribution to journalReview article

152 Scopus citations

Dialytic care of patients with acute renal failure

Yaqub, M. S. & Molitoris, B. A., Jan 2000, In : Drugs of Today. 36, 1, p. 13-24 12 p.

Research output: Contribution to journalReview article

Gentamicin traffics rapidly and directly to the Golgi complex in LLC-PK1 cells

Sandoval, R. M., Dunn, K. W. & Molitoris, B. A., Dec 7 2000, In : American Journal of Physiology - Renal Physiology. 279, 5 48-5, p. F884-F890

Research output: Contribution to journalArticle

30 Scopus citations
2001

Characteristics of EYFP-actin and visualization of actin dynamics during ATP depletion and repletion

Herget-Rosenthal, S., Hosford, M., Kribben, A., Atkinson, S. J., Sandoval, R. M. & Molitoris, B. A., Dec 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1858-C1870

Research output: Contribution to journalArticle

19 Scopus citations

Erythropoietin requirements increase following hospitalization in end-stage renal disease patients

Yaqub, M. S., Leiser, J. & Molitoris, B. A., Dec 1 2001, In : American journal of nephrology. 21, 5, p. 390-396 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Gentamicin inhibits renal protein and phospholipid metabolism in rats: Implications involving intracellular trafficking

Sundin, D. P., Sandoval, R. & Molitoris, B. A., Jan 30 2001, In : Journal of the American Society of Nephrology. 12, 1, p. 114-123 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Ischemia-induced tight junction dysfunction in the kidney

Marrs, J. A. & Molitoris, B. A., Jan 1 2001, Tight Junctions. CRC Press, p. 533-552 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Ischemic injury induces ADF relocalization to the apical domain of rat proximal tubule cells

Ashworth, S. L., Sandoval, R. M., Hosford, M., Hamburg, J. R. & Molitoris, B. A., May 1 2001, In : American Journal of Physiology - Renal Physiology. 280, 5 49-5, p. F886-F894

Research output: Contribution to journalArticle

49 Scopus citations
2002

Cardiovascular disease in patients with chronic kidney disease

Jaradat, M. I. & Molitoris, B. A., Nov 2002, In : Seminars in nephrology. 22, 6, p. 459-473 15 p.

Research output: Contribution to journalArticle

24 Scopus citations

Endothelial injury and dysfunction in ischemic acute renal failure

Molitoris, B. A., Sandoval, R. & Sutton, T. A., May 23 2002, In : Critical care medicine. 30, 5 SUPPL., p. S235-S240

Research output: Contribution to journalArticle

92 Scopus citations

Functional studies of the kidney of living animals using multicolor two-photon microscopy

Dunn, K. W., Sandoval, R. M., Kelly, K. J., Dagher, P. C., Tanner, G. A., Atkinson, S. J., Bacallao, R. L. & Molitoris, B. A., Sep 1 2002, In : American Journal of Physiology - Cell Physiology. 283, 3 52-3, p. C905-C916

Research output: Contribution to journalArticle

238 Scopus citations

Ischemia induces alterations in actin filaments in renal vascular smooth muscle cells

Kwon, O., Phillips, C. L. & Molitoris, B. A., Jan 1 2002, In : American Journal of Physiology - Renal Physiology. 282, 6 51-6, p. F1012-F1019

Research output: Contribution to journalArticle

57 Scopus citations

Microvascular endothelial injury and dysfunction during ischemic acute renal failure

Sutton, T. A., Fisher, C. J. & Molitoris, B. A., Nov 2002, In : Kidney international. 62, 5, p. 1539-1549 11 p.

Research output: Contribution to journalArticle

393 Scopus citations

Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1 cells

Sandoval, R. M., Bacallao, R. L., Dunn, K. W., Leiser, J. D. & Molitoris, B. A., Dec 1 2002, In : American Journal of Physiology - Renal Physiology. 283, 6 52-6, p. F1422-F1429

Research output: Contribution to journalArticle

7 Scopus citations
2003

ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion

Ashworth, S. L., Southgate, E. L., Sandoval, R. M., Meberg, P. J., Bamburg, J. R. & Molitoris, B. A., Apr 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 4 53-4, p. F852-F862

Research output: Contribution to journalArticle

44 Scopus citations
153 Scopus citations

Establishment of Polarity in Epithelial Cells of the Developing Nephron

Karp, S. L. & Molitoris, B. A., Mar 15 2003, The Kidney: From Normal Development to Congenital Disease. Elsevier Inc., p. 211-220 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Injury of the renal microvascular endothelium alters barrier function after ischemia

Sutton, T. A., Mang, H. E., Campos, S. B., Sandoval, R. M., Yoder, M. C. & Molitoris, B. A., Aug 1 2003, In : American Journal of Physiology - Renal Physiology. 285, 2 54-2, p. F191-F198

Research output: Contribution to journalArticle

238 Scopus citations