Bruce Molitoris

  • 15399 Citations
  • 61 h-Index
1974 …2019
If you made any changes in Pure, your changes will be visible here soon.

Publications 1974 2019

  • 15399 Citations
  • 61 h-Index
  • 223 Article
  • 20 Chapter
  • 2 Editorial
  • 1 Review article
2008
15 Citations (Scopus)

Imaging techniques in acute kidney injury

Sharfuddin, A., Sandoval, R. M. & Molitoris, B., Sep 2008, In : Nephron - Clinical Practice. 109, 4

Research output: Contribution to journalArticle

Photons
Acute Kidney Injury
Microscopy
Research Personnel
Kidney
1 Citation (Scopus)
Acute Kidney Injury
Creatinine
Serum
Mortality
Urine
50 Citations (Scopus)

Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1

Wagner, M., Rhodes, G., Wang, E., Pruthi, V., Arif, E., Saleem, M. A., Wean, S. E., Garg, P., Verma, R., Holzman, L. B., Gattone, V., Molitoris, B. & Nihalani, D., Dec 19 2008, In : Journal of Biological Chemistry. 283, 51, p. 35579-35589 11 p.

Research output: Contribution to journalArticle

Podocytes
Diaphragms
Diaphragm
Kidney
Ischemia
1 Citation (Scopus)

Pathophysiology of Acute Kidney Injury

Sharfuddin, A. & Molitoris, B., 2008, Seldin and Giebisch's The Kidney. Elsevier Inc., p. 2143-2191 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

20 Citations (Scopus)

Quantifying endocytosis in vivo using intravital two-photon microscopy

Sandoval, R. M. & Molitoris, B., 2008, Methods in Molecular Biology. Humana Press, Vol. 440. p. 389-402 14 p. (Methods in Molecular Biology; vol. 440).

Research output: Chapter in Book/Report/Conference proceedingChapter

Endocytosis
Photons
Microscopy
Research Personnel
Proximal Kidney Tubule
56 Citations (Scopus)

Technology Insight: Biomarker development in acute kidney injury - What can we anticipate?

Molitoris, B., Melnikov, V. Y., Okusa, M. D. & Himmelfarb, J., Mar 2008, In : Nature Clinical Practice Nephrology. 4, 3, p. 154-165 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Biomarkers
Technology
Early Diagnosis
Blood Urea Nitrogen
2009
25 Citations (Scopus)

Activated protein C and acute kidney injury: Selective targeting of PAR-1

Gupta, A., Williams, M. D., Macias, W. L., Molitoris, B. & Grinnell, B. W., 2009, In : Current Drug Targets. 10, 12, p. 1212-1226 15 p.

Research output: Contribution to journalArticle

PAR-1 Receptor
Protein C
Acute Kidney Injury
Protein C Deficiency
Tissue Survival
684 Citations (Scopus)

Acute kidney injury increases risk of ESRD among elderly

Ishani, A., Xue, J. L., Himmelfarb, J., Eggers, P. W., Kimmel, P. L., Molitoris, B. & Collins, A. J., Jan 2009, In : Journal of the American Society of Nephrology. 20, 1, p. 223-228 6 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Chronic Kidney Failure
Chronic Renal Insufficiency
Medicare
Confidence Intervals
1 Citation (Scopus)

ASN policy on managing conflicts of interest

Stokes, J. B., Haupt, A., Molitoris, B., Kokemueller, P. & Ibrahim, T., Sep 2009, In : Journal of the American Society of Nephrology. 20, 9, p. 1853-1859 7 p.

Research output: Contribution to journalArticle

Organizational Policy
Conflict of Interest
Nephrology
Medical Societies
36 Citations (Scopus)

Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation

Campos-Bilderback, S., Ashworth, S. L., Wean, S., Hosford, M., Sandoval, R. M., Hallett, M. A., Atkinson, S. J. & Molitoris, B., Mar 2009, In : American Journal of Physiology - Renal Physiology. 296, 3

Research output: Contribution to journalArticle

Actin Depolymerizing Factors
Actins
Stress Fibers
Endothelial Cells
Cytokines
19 Citations (Scopus)

Early monitoring of acute tubular necrosis in the rat kidney by 23Na-MRI

Atthe, B. K., Babsky, A. M., Hopewell, P. N., Phillips, C., Molitoris, B. & Bansal, N., Nov 2009, In : American Journal of Physiology - Renal Physiology. 297, 5

Research output: Contribution to journalArticle

Necrosis
Sodium
Magnetic Resonance Imaging
Ischemia
Kidney
10 Citations (Scopus)

Illuminating mitochondrial function and dysfunction using multiphoton technology

Weinberg, J. M. & Molitoris, B., Jun 2009, In : Journal of the American Society of Nephrology. 20, 6, p. 1164-1166 3 p.

Research output: Contribution to journalArticle

Multiphoton Fluorescence Microscopy
Distal Kidney Tubule
Proximal Kidney Tubule
Mitochondria
Technology
159 Citations (Scopus)

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

Russo, L. M., Sandoval, R. M., Campos-Bilderback, S., Molitoris, B., Comper, W. D. & Brown, D., Mar 2009, In : Journal of the American Society of Nephrology. 20, 3, p. 489-494 6 p.

Research output: Contribution to journalArticle

Albuminuria
Diabetic Nephropathies
Albumins
Proximal Kidney Tubule
Photons
13 Citations (Scopus)

Ironing Out the Pathogenesis of Acute Kidney Injury

Hingorani, S., Molitoris, B. & Himmelfarb, J., Apr 2009, In : American Journal of Kidney Diseases. 53, 4, p. 569-571 3 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins
Antimicrobial Cationic Peptides
Alpha-Globulins
Lipocalins
beta 2-Microglobulin
1 Citation (Scopus)

Managing conflicts of interest: The road ahead

Stokes, J. B., Berns, A. S., Henrich, W. L., McKinney, T. D., Molitoris, B. & Palmer, B. F., Sep 2009, In : Journal of the American Society of Nephrology. 20, 9, p. 1860-1862 3 p.

Research output: Contribution to journalArticle

Organizational Policy
Conflict of Interest
Nephrology
Medical Societies
194 Citations (Scopus)

siRNA targeted to p53 attenuates ischemic and cisplatin-induced acute kidney injury

Molitoris, B., Dagher, P., Sandoval, R. M., Campos-Bilderback, S., Ashush, H., Fridman, E., Brafman, A., Faerman, A., Atkinson, S. J., Thompson, J. D., Kalinski, H., Skaliter, R., Erlich, S. & Feinstein, E., Aug 2009, In : Journal of the American Society of Nephrology. 20, 8, p. 1754-1764 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Small Interfering RNA
Cisplatin
Kidney
Wounds and Injuries
84 Citations (Scopus)

Soluble thrombomodulin protects ischemic kidneys

Sharfuddin, A., Sandoval, R. M., Berg, D. T., McDougal, G. E., Campos-Bilderback, S., Phillips, C., Jones, B. E., Gupta, A., Grinnell, B. W. & Molitoris, B., Mar 2009, In : Journal of the American Society of Nephrology. 20, 3, p. 524-534 11 p.

Research output: Contribution to journalArticle

Thrombomodulin
Kidney
Protein C
Acute Kidney Injury
Microscopy
11 Citations (Scopus)

Techniques to study nephron function: Microscopy and imaging

Molitoris, B. & Sandoval, R. M., May 2009, In : Pflugers Archiv European Journal of Physiology. 458, 1, p. 203-209 7 p.

Research output: Contribution to journalArticle

Fluorophores
Nephrons
Microscopy
Microscopic examination
Animals
2010

Aminoglycoside-Induced Nephrotoxicity

Decker, B. & Molitoris, B., Aug 12 2010, Renal Toxicology. Elsevier Inc., Vol. 7. p. 329-346 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aminoglycosides
Endocytosis
Kidney
Incidence
Low Density Lipoprotein Receptor-Related Protein-2
28 Citations (Scopus)

Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models

Imamura, R., Isaka, Y., Sandoval, R. M., Ori, A., Adamsky, S., Feinstein, E., Molitoris, B. & Takahara, S., 2010, In : Cell Transplantation. 19, 12, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

Photons
Kidney Transplantation
Small Interfering RNA
Rats
Microscopy
12 Citations (Scopus)

Lessons from Haiti on disaster relief

Portilla, D., Shaffer, R. N., Okusa, M. D., Mehrotra, R., Molitoris, B., Bunchman, T. E. & Ibrahim, T., Nov 1 2010, In : Clinical Journal of the American Society of Nephrology. 5, 11, p. 2122-2129 8 p.

Research output: Contribution to journalArticle

Organizational Objectives
Disaster Medicine
Disaster Planning
Haiti
International Cooperation
11 Citations (Scopus)

Multiphoton imaging techniques in acute kidney injury

Molitoris, B. & Sandoval, R. M., Apr 2010, Contributions to Nephrology. Vol. 165. p. 46-53 8 p. (Contributions to Nephrology; vol. 165).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Kidney Injury
Microscopy
Research Personnel
Kidney
Wounds and Injuries
29 Citations (Scopus)
Glomerular Filtration Rate
Acute Kidney Injury
Dextrans
Photons
Kidney
6 Citations (Scopus)

Yet another advance in understanding albuminuria?

Molitoris, B., Dec 2010, In : Journal of the American Society of Nephrology. 21, 12, p. 2013-2015 3 p.

Research output: Contribution to journalArticle

Animal Disease Models
Podocytes
Albuminuria
Kidney Diseases
Glomerular Filtration Rate
2011
2 Citations (Scopus)

Acute Kidney Injury

Molitoris, B., Jul 2011, Goldman's Cecil Medicine: Twenty Fourth Edition. Elsevier Inc., Vol. 1. p. 756-761 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

95 Citations (Scopus)

Acute kidney injury in older adults

Anderson, S., Eldadah, B., Halter, J. B., Hazzard, W. R., Himmelfarb, J., Horne, F. M., Kimmel, P. L., Molitoris, B., Murthy, M., O'Hare, A. M., Schmader, K. E. & High, K. P., Jan 2011, In : Journal of the American Society of Nephrology. 22, 1, p. 28-38 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Geriatrics
Patient Preference
Chronic Renal Insufficiency
Creatinine
5 Citations (Scopus)

Circulating Micro-RNAs in Acute Kidney injury: Early observations

Molitoris, J. K. & Molitoris, B., Jul 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 7, p. 1517-1519 3 p.

Research output: Contribution to journalArticle

MicroRNAs
Acute Kidney Injury

Disease-specific kidney imaging: Introduction

Molitoris, B., May 2011, In : Seminars in Nephrology. 31, 3, p. 235-236 2 p.

Research output: Contribution to journalArticle

Kidney Diseases
Diagnostic Imaging
172 Citations (Scopus)

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury

Basile, D., Friedrich, J. L., Spahic, J., Knipe, N., Mang, H., Leonard, E. C., Changizi-Ashtiyani, S., Bacallao, R., Molitoris, B. & Sutton, T., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3

Research output: Contribution to journalArticle

Acute Kidney Injury
Blood Vessels
Endothelial Cells
Vascular Endothelial Growth Factor A
Bromodeoxyuridine
13 Citations (Scopus)

Implications of a Nephrology Workforce Shortage for Dialysis Patient Care

Mehrotra, R., Shaffer, R. N. & Molitoris, B., May 2011, In : Seminars in Dialysis. 24, 3, p. 275-277 3 p.

Research output: Contribution to journalArticle

Nephrology
Dialysis
Patient Care
Vulnerable Populations
Health Policy
10 Citations (Scopus)

Kidney endothelial dysfunction: Ischemia, localized infections and sepsis

Molitoris, B. & Sandoval, R. M., Sep 2011, Contributions to Nephrology. Vol. 174. p. 108-118 11 p. (Contributions to Nephrology; vol. 174).

Research output: Chapter in Book/Report/Conference proceedingChapter

Sepsis
Leukocytes
Ischemia
Kidney
Endothelial Cells
321 Citations (Scopus)

Pathophysiology of ischemic acute kidney injury

Sharfuddin, A. & Molitoris, B., Apr 2011, In : Nature Reviews Nephrology. 7, 4, p. 189-200 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Ischemia
Chronic Renal Insufficiency
Wounds and Injuries
Cell Communication
3 Citations (Scopus)

The antibiotic gentamicin inhibits specific protein trafficking functions of the arf1/2 family of GTPases

Lin, L., Wagner, M., Cocklin, R., Kuzma, A., Harrington, M., Molitoris, B. & Goebl, M., Jan 2011, In : Antimicrobial Agents and Chemotherapy. 55, 1, p. 246-254 9 p.

Research output: Contribution to journalArticle

GTP Phosphohydrolases
Protein Transport
Gentamicins
Anti-Bacterial Agents
Translational Peptide Chain Termination
73 Citations (Scopus)

The future nephrology workforce: Will there be one?

Parker, M. G., Ibrahim, T., Shaffer, R., Rosner, M. H. & Molitoris, B., Jun 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 6, p. 1501-1506 6 p.

Research output: Contribution to journalArticle

Nephrology
Mentors
Geriatrics
Medicine
Policy Making
35 Citations (Scopus)

Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact

Presson, R., Brown, M. B., Fisher, A. J., Sandoval, R. M., Dunn, K., Lorenz, K. S., Delp, E. J., Salama, P., Molitoris, B. & Petrache, I., Jul 2011, In : American Journal of Pathology. 179, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

Photons
Artifacts
Thorax
Microscopy
Leukocytes
81 Citations (Scopus)

Uropathogenic escherichia coli P and type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction

Melican, K., Sandoval, R. M., Kader, A., Josefsson, L., Tanner, G. A., Molitoris, B. & Richter-Dahlfors, A., Feb 2011, In : PLoS Pathogens. 7, 2, e1001298.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Nephrons
Bacterial Infections
Epithelium
Bowman Capsule
2012
12 Citations (Scopus)

A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney

Imamura, R., Isaka, Y., Sandoval, R. M., Ichimaru, N., Abe, T., Okumi, M., Yazawa, K., Kitamura, H., Kaimori, J., Nonomura, N., Rakugi, H., Molitoris, B. & Takahara, S., Dec 2012, In : Clinical and Experimental Nephrology. 16, 6, p. 852-862 11 p.

Research output: Contribution to journalArticle

Erythropoietin
Fibrosis
Kidney
Hemoglobins
carbamylated erythropoietin
50 Citations (Scopus)

A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals

Wang, E., Meier, D. J., Sandoval, R. M., Von Hendy-Willson, V. E., Pressler, B. M., Bunch, R. M., Alloosh, M., Sturek, M., Schwartz, G. J. & Molitoris, B., Jan 1 2012, In : Kidney International. 81, 1, p. 112-117 6 p.

Research output: Contribution to journalArticle

Point-of-Care Systems
Glomerular Filtration Rate
Fluorescence
Plasma Volume
Blood Vessels
13 Citations (Scopus)

Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat

Saleh, M. A., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S., Molitoris, B. & Pollock, D. M., Oct 15 2012, In : Life Sciences. 91, 13-14, p. 634-637 4 p.

Research output: Contribution to journalArticle

Endothelin-1
Rats
Albumins
Albuminuria
Permeability
9 Citations (Scopus)

Designing clinical trials in acute kidney injury

Molitoris, B., Okusa, M. D., Palevsky, P. M., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 842-843 2 p.

Research output: Contribution to journalArticle

Translational Medical Research
Acute Kidney Injury
Clinical Trials
65 Citations (Scopus)

Design of clinical trials in acute kidney injury: Report from an NIDDK workshop on trial methodology

Palevsky, P. M., Molitoris, B., Okusa, M. D., Levin, A., Waikar, S. S., Wald, R., Chertow, G. M., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Faubel, S. G., Kellum, J. A., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 844-850 7 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Acute Kidney Injury
Clinical Trials
Education
Sample Size
31 Citations (Scopus)

Design of clinical trials in acute kidney injury: A report from an NIDDK workshop-prevention trials

Okusa, M. D., Molitoris, B., Palevsky, P. M., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Faubel, S., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T. H., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 851-855 5 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Acute Kidney Injury
Clinical Trials
Education
Mortality
26 Citations (Scopus)

Design of clinical trials in AKI: A report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings

Molitoris, B., Okusa, M. D., Palevsky, P. M., Chawla, L. S., Kaufman, J. S., Devarajan, P., Toto, R. M., Hsu, C. Y., Greene, T. H., Faubel, S. G., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chinchilli, V. M. & 15 others, Liu, K. D., Cheung, A. K., Weisbord, S. D., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 856-860 5 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Sepsis
Clinical Trials
Education
Wounds and Injuries
6 Citations (Scopus)

Measuring glomerular filtration rate in acute kidney injury: Yes, but not yet

Molitoris, B., Sep 24 2012, In : Critical Care. 16, 5, 158.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Acute Kidney Injury
Biomarkers
Critical Care
Creatinine
11 Citations (Scopus)

Multiphoton microscopy applied for real-time intravital imaging of bacterial infections in vivo

Choong, F. X., Sandoval, R. M., Molitoris, B. & Richter-Dahlfors, A., 2012, In : Methods in Enzymology. 506, p. 35-61 27 p.

Research output: Contribution to journalArticle

Bacterial Infections
Microscopy
Microscopic examination
Imaging techniques
Infection
61 Citations (Scopus)

Multiple factors influence glomerular albumin permeability in rats

Sandoval, R. M., Wagner, M., Patel, M., Campos-Bilderback, S., Rhodes, G. J., Wang, E., Wean, S. E., Clendenon, S. S. & Molitoris, B., Mar 2012, In : Journal of the American Society of Nephrology. 23, 3, p. 447-457 11 p.

Research output: Contribution to journalArticle

Albumins
Permeability
Wistar Rats
Microscopy
Transcytosis
42 Citations (Scopus)

Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration

Thompson, J. D., Kornbrust, D. J., Foy, J. W. D., Solano, E. C. R., Schneider, D. J., Feinstein, E., Molitoris, B. & Erlich, S., Aug 1 2012, In : Nucleic Acid Therapeutics. 22, 4, p. 255-264 10 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Intravenous Administration
Toxicology
RNA
Reperfusion Injury
2013
31 Citations (Scopus)

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

Research
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Kidney
Kidney Diseases
Animal Models
1 Citation (Scopus)

AKI is around the world but public recognition is lacking

Molitoris, B., 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1467-1468 2 p.

Research output: Contribution to journalArticle

Health Knowledge, Attitudes, Practice
Health Policy
Acute Kidney Injury
Biomedical Research
82 Citations (Scopus)

In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury

Hall, A. M., Rhodes, G. J., Sandoval, R. M., Corridon, P. R. & Molitoris, B., Jan 2013, In : Kidney International. 83, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Ischemia
Mitochondrial Membrane Potential
NAD