Bruce Molitoris

  • 16099 Citations
  • 62 h-Index
1974 …2020

Research output per year

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Publications

2020

Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine

Liu, X. F., Wei, J., Zhou, Q., Molitoris, B. A., Sandoval, R., Kobayashi, H., Okada, R., Nagaya, T., Karim, B., Butcher, D. & Pastan, I., Mar 17 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6086-6091 6 p.

Research output: Contribution to journalArticle

2019

A novel fluorescent clinical method to rapidly quantify plasma volume

Molitoris, B. A., George, A. G., Murray, P. T., Meier, D., Reilly, E. S., Barreto, E., Sandoval, R. M., Rizk, D. V., Shaw, A. D. & Peacock, W. F., Mar 1 2019, In : CardioRenal Medicine. 9, 3, p. 168-179 12 p.

Research output: Contribution to journalArticle

Open Access

Application of physiological shear stress to renal tubular epithelial cells

Ferrell, N., Sandoval, R. M., Molitoris, B. A., Brakeman, P., Roy, S. & Fissell, W. H., 2019, Methods in Cell Biology. Weimbs, T. (ed.). Academic Press Inc., p. 43-67 25 p. (Methods in Cell Biology; vol. 153).

Research output: Chapter in Book/Report/Conference proceedingChapter

Beyond Biomarkers: Machine Learning in Diagnosing Acute Kidney Injury

Molitoris, B. A., May 2019, In : Mayo Clinic Proceedings. 94, 5, p. 748-750 3 p.

Research output: Contribution to journalEditorial

1 Scopus citations

DNA damage response protects against progressive kidney disease

Molitoris, B. A., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4574-4575 2 p.

Research output: Contribution to journalReview article

1 Scopus citations

Fluorescent Imaging and Microscopy for Dynamic Processes in Rats

Sandoval, R. M., Molitoris, B. & Palygin, O., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 151-175 25 p. (Methods in Molecular Biology; vol. 2018).

Research output: Chapter in Book/Report/Conference proceedingChapter

Kidney Mentoring and Assessment Program for Students: A guide for engaging medical students in nephrology

Bayliss, G. P., Cobb, J., Decker, B., Hellman, R., Vasavada, N., MacKelaite, L., Shadur, C., Ilori, T., Ibrahim, T., Leight, K., Hsiao, L. L., Molitoris, B. A., Okusa, M. D. & Parker, M. G., Feb 25 2019, In : Clinical Kidney Journal. 12, 6, p. 761-766 6 p.

Research output: Contribution to journalArticle

Open Access

Practical Considerations of Renal Biopsies in Critical Care Patients

Modi, J. R., Liapis, H., Molitoris, B. A. & Eadon, M. T., Jan 1 2019, Critical Care Nephrology: Third Edition. Elsevier Inc., p. 167-173.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration

Uchida, M., Maier, B., Waghwani, H. K., Selivanovitch, E., Louise Pay, S., Avera, J., Jun Yun, E., Sandoval, R. M., Molitoris, B. A., Zollman, A., Douglas, T. & Hato, T., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3941-3951 11 p.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

The Physiology of the Glomerulus

Dean, D. F. & Molitoris, B. A., Jan 1 2019, Critical Care Nephrology: Third Edition. Elsevier Inc., p. 35-42.e2

Research output: Chapter in Book/Report/Conference proceedingChapter

2018

Aminoglycoside-Induced Nephrotoxicity

Decker, B. S. & Molitoris, B. A., Jan 1 2018, Renal Toxicology. Elsevier Inc., Vol. 14-15. p. 256-273 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

A novel method for rapid bedside measurement of GFR

Rizk, D. V., Meier, D., Sandoval, R. M., Chacana, T., Reilly, E. S., Seegmiller, J. C., DeNoia, E., Strickland, J. S., Muldoon, J. & Molitoris, B. A., Jun 2018, In : Journal of the American Society of Nephrology. 29, 6, p. 1609-1613 5 p.

Research output: Contribution to journalArticle

11 Scopus citations
26 Scopus citations

Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection

Kolb, A. L., Corridon, P. R., Zhang, S., Xu, W., Witzmann, F., Collett, J. A., Rhodes, G. J., Winfree, S., Bready, D., Pfeffenberger, Z. J., Pomerantz, J. M., Hato, T., Nagami, G. T., Molitoris, B., Basile, D., Atkinson, S. J. & Bacallao, R., Apr 1 2018, In : Journal of the American Society of Nephrology. 29, 4, p. 1154-1164 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Protective vascular coagulation in response to bacterial infection of the kidney is regulated by bacterial lipid A and host CD147

Schulz, A., Chuquimia, O. D., Antypas, H., Steiner, S. E., Sandoval, R. M., Tanner, G. A., Molitoris, B. A., Richter-Dahlfors, A. & Melican, K., Nov 1 2018, In : Pathogens and Disease. 76, 8, fty087.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Hydrodynamic isotonic fluid delivery ameliorates moderate-to-severe ischemia-reperfusion injury in rat kidneys

Collett, J. A., Corridon, P. R., Mehrotra, P., Kolb, A. L., Rhodes, G. J., Miller, C. A., Molitoris, B. A., Pennington, J. G., Sandoval, R. M., Atkinson, S. J., Campos-Bilderback, S. B., Basile, D. P. & Bacallao, R. L., Jul 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2081-2092 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibition of avb5 integrin attenuates vascular permeability and protects against renal ischemia-reperfusion injury

McCurley, A., Alimperti, S., Campos-Bilderback, S. B., Sandoval, R. M., Calvino, J. E., Reynolds, T. L., Quigley, C., Mugford, J. W., Polacheck, W. J., Gomez, I. G., Dovey, J., Marsh, G., Huang, A., Qian, F., Weinreb, P. H., Dolinski, B. M., Moore, S., Duffield, J. S., Chen, C. S., Molitoris, B. A. & 2 others, Violette, S. M. & Crackower, M. A., Jun 2017, In : Journal of the American Society of Nephrology. 28, 6, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Intravital imaging of the kidney in a rat model of salt-sensitive hypertension

Endres, B. T., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S., Kamocka, M., McDermott-Roe, C., Staruschenko, A., Molitoris, B., Geurts, A. M. & Palygin, O., Aug 1 2017, In : American Journal of Physiology - Renal Physiology. 313, 2, p. F163-F173

Research output: Contribution to journalArticle

7 Scopus citations

Intravital multiphoton microscopy as a tool for studying renal physiology and pathophysiology

Sandoval, R. M. & Molitoris, B. A., Sep 1 2017, In : Methods. 128, p. 20-32 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Two-photon intravital fluorescence lifetime imaging of the kidney reveals cell-type specific metabolic signatures

Hato, T., Winfree, S., Day, R., Sandoval, R. M., Molitoris, B. A., Yoder, M. C., Wiggins, R. C., Zheng, Y., Dunn, K. W. & Dagher, P. C., Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2420-2430 11 p.

Research output: Contribution to journalArticle

28 Scopus citations
2016

ABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial

Mccullough, P. A., Bennett-Guerrero, E., Chawla, L. S., Beaver, T., Mehta, R. L., Molitoris, B. A., Eldred, A., Ball, G., Lee, H. J., Houser, M. T. & Khan, S., Aug 2016, In : Journal of the American Heart Association. 5, 8, e003549.

Research output: Contribution to journalArticle

14 Scopus citations

Mechanism of increased clearance of glycated albumin by proximal tubule cells

Wagner, M. C., Myslinski, J., Pratap, S., Flores, B., Rhodes, G., Campos-Bilderback, S. B., Sandoval, R. M., Kumar, S., Patel, M., Ashish & Molitoris, B. A., May 15 2016, In : American Journal of Physiology - Renal Physiology. 310, 10, p. F1089-F1102

Research output: Contribution to journalArticle

9 Scopus citations

Proximal tubules have the capacity to regulate uptake of albumin

Wagner, M. C., Campos-Bilderback, S. B., Chowdhury, M., Flores, B., Lai, X., Myslinski, J., Pandit, S., Sandoval, R. M., Wean, S. E., Wei, Y., Satlin, L. M., Wiggins, R. C., Witzmann, F. A. & Molitoris, B. A., Feb 2016, In : Journal of the American Society of Nephrology. 27, 2, p. 482-494 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Quantifying Glomerular Filtration Rates in Acute Kidney Injury: A Requirement for Translational Success

Molitoris, B. & Reilly, E. S., 2016, (Accepted/In press) In : Seminars in Nephrology.

Research output: Contribution to journalArticle

22 Scopus citations

Renal Hemodynamics in AKI: In Search of New Treatment Targets

The ADQI XIII Work Group, Jan 2016, In : Journal of the American Society of Nephrology. 27, 1, p. 49-58 10 p.

Research output: Contribution to journalArticle

46 Scopus citations
7 Scopus citations

Tubular mechanisms in proteinuria

Verma, S. K. & Molitoris, B. A., Jan 1 2016, Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance. Springer International Publishing, p. 23-40 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2015

Contrast material-induced nephropathy: Causation quandaries

Mitchell, A. M., Molitoris, B. A. & Teague, S. D., Jun 1 2015, In : Radiology. 275, 3, p. 928-929 2 p.

Research output: Contribution to journalLetter

3 Scopus citations

Cross-disciplinary biomarkers research: Lessons learned by the CKD biomarkers consortium

CKD Biomarkers Consortium, Jan 1 2015, In : Clinical Journal of the American Society of Nephrology. 10, 5, p. 894-902 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Nephrology research - The past, present and future

Floege, J., Mak, R. H., Molitoris, B. A., Remuzzi, G. & Ronco, P., Nov 1 2015, In : Nature Reviews Nephrology. 11, 11, p. 677-687 11 p.

Research output: Contribution to journalReview article

14 Scopus citations

Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): A randomised clinical trial

de Zeeuw, D., Anzalone, D. A., Cain, V. A., Cressman, M. D., Heerspink, H. J. L., Molitoris, B. A., Monyak, J. T., Parving, H. H., Remuzzi, G., Sowers, J. R. & Vidt, D. G., Mar 1 2015, In : The Lancet Diabetes and Endocrinology. 3, 3, p. 181-190 10 p.

Research output: Contribution to journalArticle

70 Scopus citations

Renal Endothelial Injury and Microvascular Dysfunction in Acute Kidney Injury

Verma, S. K. & Molitoris, B. A., Jan 1 2015, In : Seminars in Nephrology. 35, 1, p. 96-107 12 p.

Research output: Contribution to journalReview article

57 Scopus citations

Shear stress is normalized in glomerular capillaries following 5⁄6 nephrectomy

Ferrell, N., Sandoval, R. M., Bian, A., Campos-Bilderback, S. B., Molitoris, B. A. & Fissell, W. H., Mar 15 2015, In : American Journal of Physiology - Renal Physiology. 308, 6, p. F588-F593

Research output: Contribution to journalArticle

13 Scopus citations

Urinary biomarkers: Alone are they enough?

Molitoris, B. A., Jul 1 2015, In : Journal of the American Society of Nephrology. 26, 7, p. 1485-1488 4 p.

Research output: Contribution to journalReview article

12 Scopus citations
2014
3 Scopus citations

Dynamic multiphoton microscopy: Focusing light on acute kidney injury

Hall, A. M. & Molitoris, B. A., Sep 1 2014, In : Physiology. 29, 5, p. 334-342 9 p.

Research output: Contribution to journalReview article

20 Scopus citations

Effects of biomechanical forces on signaling in the cortical collecting duct (CCD)

Carrisoza-Gaytan, R., Liu, Y., Flores, D., Else, C., Lee, H. G., Rhodes, G., Sandoval, R. M., Kleyman, T. R., Lee, F. Y. I., Molitoris, B., Satlin, L. M. & Rohatgi, R., Jul 15 2014, In : American Journal of Physiology - Renal Physiology. 307, 2, p. F195-F204

Research output: Contribution to journalArticle

19 Scopus citations

Fluorescent dextrans in intravital multi- photon microscopy

Sandoval, R. M. & Molitoris, B., Jan 1 2014, Advances in Intravital Microscopy: From Basic to Clinical Research. Springer Netherlands, p. 205-219 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

6 Scopus citations

Screening: Screening for kidney disease- A lost opportunity

Molitoris, B. A., Jan 1 2014, In : Nature Reviews Nephrology. 10, 1, p. 6-8 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

The proximal tubule and albuminuria: Really!

Dickson, L. E., Wagner, M. C., Sandoval, R. M. & Molitoris, B. A., Mar 1 2014, In : Journal of the American Society of Nephrology. 25, 3, p. 443-453 11 p.

Research output: Contribution to journalReview article

132 Scopus citations

Therapeutic translation in acute kidney injury: The epithelial/endothelial axis

Molitoris, B. A., Jun 2 2014, In : Journal of Clinical Investigation. 124, 6, p. 2355-2363 9 p.

Research output: Contribution to journalReview article

100 Scopus citations

Using 2-photon microscopy to understand albuminuria

Molitoris, B. A., Jan 1 2014, In : Transactions of the American Clinical and Climatological Association. 125, p. 343-56; discussion 356-7

Research output: Contribution to journalReview article

2 Scopus citations
2013

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

31 Scopus citations

AKI is around the world but public recognition is lacking

Molitoris, B. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1467-1468 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury

Hall, A. M., Rhodes, G. J., Sandoval, R. M., Corridon, P. R. & Molitoris, B. A., Jan 2013, In : Kidney international. 83, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

90 Scopus citations

Measuring glomerular filtration rate in the intensive care unit: No substitutes please

Molitoris, B. A., Sep 4 2013, In : Critical Care. 17, 5, 181.

Research output: Contribution to journalComment/debate

19 Scopus citations

Pathophysiology of Acute Kidney Injury

Molitoris, B. A. & Sharfuddin, A., Aug 29 2013, Seldin and Geibisch's The Kidney. Elsevier Inc., Vol. 2. p. 2527-2575 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations
18 Scopus citations