Bruce Molitoris

  • 15823 Citations
  • 62 h-Index
1974 …2019

Research output per year

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Publications

9 Scopus citations

ABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial

Mccullough, P. A., Bennett-Guerrero, E., Chawla, L. S., Beaver, T., Mehta, R. L., Molitoris, B. A., Eldred, A., Ball, G., Lee, H. J., Houser, M. T. & Khan, S., Aug 2016, In : Journal of the American Heart Association. 5, 8, e003549.

Research output: Contribution to journalArticle

14 Scopus citations

Actin cytoskeleton in ischemic acute renal failure

Molitoris, B. A., Harrington, J. T., Perrone, R., Jaber, B., Herman, I. M., Balakrishnan, V. S., Pahari, D. K. & Levey, A. S., Aug 2004, In : Kidney international. 66, 2, p. 871-883 13 p.

Research output: Contribution to journalArticle

53 Scopus citations

Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2

Gupta, A., Rhodes, G. J., Berg, D. T., Gerlitz, B., Molitoris, B. A. & Grinnell, B. W., Jul 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 1, p. F245-F254

Research output: Contribution to journalArticle

108 Scopus citations

Activated protein C and acute kidney injury: Selective targeting of PAR-1

Gupta, A., Williams, M. D., Macias, W. L., Molitoris, B. A. & Grinnell, B. W., Dec 1 2009, In : Current Drug Targets. 10, 12, p. 1212-1226 15 p.

Research output: Contribution to journalReview article

25 Scopus citations

Acute Kidney Injury

Molitoris, B. A., Jul 1 2011, Goldman's Cecil Medicine: Twenty Fourth Edition. Elsevier Inc., Vol. 1. p. 756-761 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Acute kidney injury increases risk of ESRD among elderly

Ishani, A., Xue, J. L., Himmelfarb, J., Eggers, P. W., Kimmel, P. L., Molitoris, B. A. & Collins, A. J., Jan 1 2009, In : Journal of the American Society of Nephrology. 20, 1, p. 223-228 6 p.

Research output: Contribution to journalArticle

711 Scopus citations

Acute kidney injury in older adults

Anderson, S., Eldadah, B., Halter, J. B., Hazzard, W. R., Himmelfarb, J., Horne, F. M. F., Kimmel, P. L., Molitoris, B. A., Murthy, M., O'Hare, A. M., Schmader, K. E. & High, K. P., Jan 1 2011, In : Journal of the American Society of Nephrology. 22, 1, p. 28-38 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Acute kidney injury network: Report of an initiative to improve outcomes in acute kidney injury

Mehta, R. L., Kellum, J. A., Shah, S. V., Molitoris, B. A., Ronco, C., Warnock, D. G., Levin, A., Bagga, A., Bakkaloglu, A., Bonventre, J. V., Burdmann, E. A., Chen, Y., Devarajan, P., D'Intini, V., Dobb, G., Durbin, C. G., Eckardt, K. U., Guerin, C., Herget-Rosenthal, S., Hoste, E. & 19 others, Joannidis, M., Kellum, J. A., Kirpalani, A., Lassnigg, A., Le Gall, J. R., Levin, A., Lombardi, R., Macias, W., Manthous, C., Mehta, R. L., Molitoris, B. A., Ronco, C., Schetz, M., Schortgen, F., Shah, S. V., Tan, P. S. K., Wang, H., Warnock, D. G. & Webb, S., Mar 1 2007, In : Critical Care. 11, R31.

Research output: Contribution to journalArticle

4151 Scopus citations

Acute parathyroid hormone stimulation of myo inositol release by isolated perfused dog kidneys

Molitoris, B. A., Hruska, K. & Daughaday, W. H., Jan 1 1976, In : Clinical research. 24, 4, p. 530A

Research output: Contribution to journalArticle

Acute renal failure

Molitoris, B. A., Sep 1 1999, In : Drugs of Today. 35, 9, p. 659-666 8 p.

Research output: Contribution to journalReview article

10 Scopus citations

Acute renal failure in the 21st century: Recommendations for management and outcomes assessment

DuBose, T. D., Warnock, D. G., Mehta, R. L., Bonventre, J. V., Hammerman, M. R., Molitoris, B. A., Paller, M. S., Siegel, N. J., Scherbenske, J. & Striker, G. E., May 1997, In : American Journal of Kidney Diseases. 29, 5, p. 793-799 7 p.

Research output: Contribution to journalArticle

88 Scopus citations

Acute renal failure in the new millennium: Time to consider combination therapy

Kelly, K. J. & Molitoris, B. A., Jan 26 2000, In : Seminars in Nephrology. 20, 1, p. 4-19 16 p.

Research output: Contribution to journalReview article

152 Scopus citations

Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: Enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model

Raikwar, S. P., Temm, C. J., Raikwar, N. S., Kao, C., Molitoris, B. A. & Gardner, T. A., Dec 1 2005, In : Molecular Therapy. 12, 6, p. 1091-1100 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion

Ashworth, S. L., Southgate, E. L., Sandoval, R. M., Meberg, P. J., Bamburg, J. R. & Molitoris, B. A., Apr 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 4 53-4, p. F852-F862

Research output: Contribution to journalArticle

44 Scopus citations

Advances in imaging the kidney and cellular processes

Herget-Rosenthal, S. & Molitoris, B. A., Mar 1 2006, In : Nephron - Experimental Nephrology. 103, 2, p. e31-e32

Research output: Contribution to journalEditorial

1 Scopus citations

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

31 Scopus citations

AKI is around the world but public recognition is lacking

Molitoris, B. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1467-1468 2 p.

Research output: Contribution to journalEditorial

1 Scopus citations

Alterations in epithelial polarity and the pathogenesis of disease states

Epstein, F. H., Fish, E. M. & Molitoris, B. A., Jun 2 1994, In : New England Journal of Medicine. 330, 22, p. 1580-1588 9 p.

Research output: Contribution to journalReview article

180 Scopus citations

Alterations in the establishment and maintenance of epithelial cell polarity as a basis for disease processes

Molitoris, B. A. & Nelson, W. J., Jan 1990, In : Journal of Clinical Investigation. 85, 1, p. 3-9 7 p.

Research output: Contribution to journalReview article

Open Access
93 Scopus citations

Aminoglycoside antibiotics traffic to the Golgi complex in LLC-PK1 cells

Sandoval, R., Leiser, J. & Molitoris, B. A., Feb 1 1998, In : Journal of the American Society of Nephrology. 9, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

Aminoglycoside-Induced Nephrotoxicity

Decker, B. & Molitoris, B., Aug 12 2010, Renal Toxicology. Elsevier Inc., Vol. 7. p. 329-346 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aminoglycoside-Induced Nephrotoxicity

Decker, B. S. & Molitoris, B. A., Jan 1 2018, Renal Toxicology. Elsevier Inc., Vol. 14-15. p. 256-273 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney

Imamura, R., Isaka, Y., Sandoval, R. M., Ichimaru, N., Abe, T., Okumi, M., Yazawa, K., Kitamura, H., Kaimori, J., Nonomura, N., Rakugi, H., Molitoris, B. A. & Takahara, S., Dec 1 2012, In : Clinical and Experimental Nephrology. 16, 6, p. 852-862 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

A non-nephrotoxic gentamicin congener that retains antimicrobial efficacy

Sandoval, R. M., Reilly, J. P., Running, W., Campos, S. B., Santos, J. R., Phillips, C. L. & Molitoris, B. A., Oct 1 2006, In : Journal of the American Society of Nephrology. 17, 10, p. 2697-2705 9 p.

Research output: Contribution to journalArticle

28 Scopus citations

A novel fluorescent clinical method to rapidly quantify plasma volume

Molitoris, B. A., George, A. G., Murray, P. T., Meier, D., Reilly, E. S., Barreto, E., Sandoval, R. M., Rizk, D. V., Shaw, A. D. & Peacock, W. F., Mar 1 2019, In : CardioRenal Medicine. 9, 3, p. 168-179 12 p.

Research output: Contribution to journalArticle

Open Access

A novel method for rapid bedside measurement of GFR

Rizk, D. V., Meier, D., Sandoval, R. M., Chacana, T., Reilly, E. S., Seegmiller, J. C., DeNoia, E., Strickland, J. S., Muldoon, J. & Molitoris, B. A., Jun 2018, In : Journal of the American Society of Nephrology. 29, 6, p. 1609-1613 5 p.

Research output: Contribution to journalArticle

8 Scopus citations
152 Scopus citations

Apically and basolaterally internalized aminoglycosides colocalize in LLC- PK1 lysosomes and alter cell function

Ford, D. M., Dahl, R. H., Lamp, C. A. & Molitoris, B. A., Jan 1 1994, In : American Journal of Physiology - Cell Physiology. 266, 1 35-1, p. C52-C57

Research output: Contribution to journalArticle

23 Scopus citations

A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals

Wang, E., Meier, D. J., Sandoval, R. M., Von Hendy-Willson, V. E., Pressler, B. M., Bunch, R. M., Alloosh, M., Sturek, M. S., Schwartz, G. J. & Molitoris, B. A., Jan 1 2012, In : Kidney international. 81, 1, p. 112-117 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Application of physiological shear stress to renal tubular epithelial cells

Ferrell, N., Sandoval, R. M., Molitoris, B., Brakeman, P., Roy, S. & Fissell, W. H., Jan 1 2019, Methods in Cell Biology. Academic Press Inc., (Methods in Cell Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

ASN policy on managing conflicts of interest

Stokes, J. B., Haupt, A., Molitoris, B. A., Kokemueller, P. & Ibrahim, T., Sep 1 2009, In : Journal of the American Society of Nephrology. 20, 9, p. 1853-1859 7 p.

Research output: Contribution to journalComment/debate

1 Scopus citations
3 Scopus citations

Assessment of the quantity of biologically available choline in soybean meal.

Molitoris, B. A. & Baker, D. H., Feb 1976, In : Journal of animal science. 42, 2, p. 481-489 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

A statistical method for determining the breakpoint of two lines

Jones, R. H. & Molitoris, B. A., Aug 15 1984, In : Analytical biochemistry. 141, 1, p. 287-290 4 p.

Research output: Contribution to journalArticle

149 Scopus citations

ATP depletion alters myosin Iβ cellular location in LLC-PK1 cells

Wagner, M. C. & Molitoris, B. A., Jun 26 1997, In : American Journal of Physiology - Cell Physiology. 272, 5 41-5, p. C1680-C1690

Research output: Contribution to journalArticle

29 Scopus citations

Authors' response

Mehta, R. L., Kellum, J. A., Shah, S. V., Molitoris, B. A., Ronco, C., Warnock, D. G., Levin, A. & Joannidis, M., Jul 25 2008, In : Critical Care. 12, 4, 423.

Research output: Contribution to journalLetter

Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis

Melican, K., Boekel, J., Månsson, L. E., Sandoval, R. M., Tanner, G. A., Källskog, Ö., Palm, F., Molitoris, B. A. & Richter-Dahlfors, A., Sep 16 2008, In : Cellular Microbiology. 10, 10, p. 1987-1998 12 p.

Research output: Contribution to journalArticle

72 Scopus citations

Beta-2-Microglobulin-Associated amyloidosis in chronic hemodialysis patients with carpal tunnel syndrome

Ullian, M. E., Hammond, W. S., Alfrey, A. C., Schultz, A. & Molitoris, B. A., Mar 1989, In : Medicine (United States). 68, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Beyond Biomarkers: Machine Learning in Diagnosing Acute Kidney Injury

Molitoris, B., May 1 2019, In : Mayo Clinic Proceedings. 94, 5, p. 748-750 3 p.

Research output: Contribution to journalEditorial

Bilateral congenital renal arteriovenous fistulas

Ullian, M. E. & Molitoris, B. A., Jan 1 1987, In : Clinical Nephrology. 27, 6, p. 293-297 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Cardiovascular disease in patients with chronic kidney disease

Jaradat, M. I. & Molitoris, B. A., Nov 2002, In : Seminars in nephrology. 22, 6, p. 459-473 15 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cell biology of aminoglycoside nephrotoxicity: Newer aspects

Molitoris, B. A., Jan 1 1997, In : Current Opinion in Nephrology and Hypertension. 6, 4, p. 384-388 5 p.

Research output: Contribution to journalReview article

24 Scopus citations

Cellular ATP depletion induces disruption of the spectrin cytoskeletal network

Molitoris, B. A., Dahl, R. & Hosford, M., Dec 1 1996, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 271, 4 40-4, p. F790-F798

Research output: Contribution to journalArticle

55 Scopus citations

Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment

Sundin, D. P., Meyer, C., Dahl, R., Geerdes, A., Sandoval, R. & Molitoris, B. A., May 21 1997, In : American Journal of Physiology - Cell Physiology. 272, 4 41-4, p. C1309-C1318

Research output: Contribution to journalArticle

21 Scopus citations

Characteristics of EYFP-actin and visualization of actin dynamics during ATP depletion and repletion

Herget-Rosenthal, S., Hosford, M., Kribben, A., Atkinson, S. J., Sandoval, R. M. & Molitoris, B. A., Dec 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1858-C1870

Research output: Contribution to journalArticle

19 Scopus citations

Characterization of ischemia-induced loss of epithelial polarity

Molitoris, B. A., Hoilien, C. A., Dahl, R., Ahnen, D. J., Wilson, P. D. & Kim, J., Dec 1 1988, In : The Journal of Membrane Biology. 106, 3, p. 233-242 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Characterization of the beta2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B., 1994, In : The American journal of physiology. 267, 3 part 2

Research output: Contribution to journalArticle

Characterization of the β2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B. A., Jan 1 1994, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 267, 3 36-3, p. F380-F389

Research output: Contribution to journalArticle

22 Scopus citations

Choline utilization in the chick as influenced by levels of dietary protein and methionine

Molitoris, B. A. & Baker, D. H., Jan 1 1976, In : Journal of Nutrition. 106, 3, p. 412-418 7 p.

Research output: Contribution to journalArticle

19 Scopus citations