Bruce Molitoris

  • 15617 Citations
  • 62 h-Index
1974 …2019
If you made any changes in Pure, your changes will be visible here soon.

Publications 1974 2019

  • 15617 Citations
  • 62 h-Index
  • 224 Article
  • 20 Chapter
  • 2 Editorial
  • 1 Review article
13 Citations (Scopus)

Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat

Saleh, M. A., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S., Molitoris, B. & Pollock, D. M., Oct 15 2012, In : Life Sciences. 91, 13-14, p. 634-637 4 p.

Research output: Contribution to journalArticle

Endothelin-1
Rats
Albumins
Albuminuria
Permeability
5 Citations (Scopus)

Circulating Micro-RNAs in Acute Kidney injury: Early observations

Molitoris, J. K. & Molitoris, B., Jul 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 7, p. 1517-1519 3 p.

Research output: Contribution to journalArticle

MicroRNAs
Acute Kidney Injury
87 Citations (Scopus)

Citrate: A major factor in the toxicity of orally administered aluminum compounds

Molitoris, B., Froment, D. H., Mackenzie, T. A., Huffer, W. H. & Alfrey, A. C., 1989, In : Kidney International. 36, 6, p. 949-953 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

Cofilin mediates ATP depletion-induced endothelial cell actin alterations

Suurna, M. V., Ashworth, S. L., Hosford, M., Sandoval, R. M., Wean, S. E., Shah, B. M., Bamburg, J. R. & Molitoris, B., Jun 2006, In : American Journal of Physiology - Renal Physiology. 290, 6

Research output: Contribution to journalArticle

Actin Depolymerizing Factors
Actins
Endothelial Cells
Adenosine Triphosphate
Destrin
21 Citations (Scopus)

Concentration of Myo-inositol in skeletal muscle of the rat occurs without active transport

Molitoris, B., Karl, I. E. & Daughaday, W. H., 1980, In : Journal of Clinical Investigation. 65, 4, p. 783-788 6 p.

Research output: Contribution to journalArticle

Active Biological Transport
Inositol
Skeletal Muscle
Phosphatidylinositols
Muscles
3 Citations (Scopus)

Contrast material-induced nephropathy: Causation quandaries

Mitchell, A., Molitoris, B. & Teague, S. D., Jun 1 2015, In : Radiology. 275, 3, p. 928-929 2 p.

Research output: Contribution to journalArticle

X Ray Computed Tomography
Acute Kidney Injury
Causality
Contrast Media
9 Citations (Scopus)
Chronic Renal Insufficiency
Outcome Assessment (Health Care)
Kidney
Acute Kidney Injury
Chronic Kidney Failure
26 Citations (Scopus)

Controversies in nephrology: Response to 'renal albumin handling, facts, and artifacts'

Russo, L. M., Sandoval, R. M., Brown, D., Molitoris, B. & Comper, W. D., Nov 2007, In : Kidney International. 72, 10, p. 1195-1197 3 p.

Research output: Contribution to journalArticle

Nephrology
Artifacts
Albumins
Kidney
Albuminuria
10 Citations (Scopus)
LLC-PK1 Cells
Gold
gold
proximal tubules
Molecular Weight
Gentamicins
16 Citations (Scopus)

Cross-disciplinary biomarkers research: Lessons learned by the CKD biomarkers consortium

CKD Biomarkers Consortium, Jan 1 2015, In : Clinical Journal of the American Society of Nephrology. 10, 5, p. 894-902 9 p.

Research output: Contribution to journalArticle

Biomarkers
Research
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Feasibility Studies
Quality Control
36 Citations (Scopus)

Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation

Campos-Bilderback, S., Ashworth, S. L., Wean, S., Hosford, M., Sandoval, R. M., Hallett, M. A., Atkinson, S. J. & Molitoris, B., Mar 2009, In : American Journal of Physiology - Renal Physiology. 296, 3

Research output: Contribution to journalArticle

Actin Depolymerizing Factors
Actins
Stress Fibers
Endothelial Cells
Cytokines
133 Citations (Scopus)
Cytoskeleton
Ischemia
Membranes
Octoxynol
Actin Cytoskeleton
9 Citations (Scopus)

Designing clinical trials in acute kidney injury

Molitoris, B. A., Okusa, M. D., Palevsky, P. M., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 842-843 2 p.

Research output: Contribution to journalArticle

Translational Medical Research
Acute Kidney Injury
Clinical Trials
67 Citations (Scopus)

Design of clinical trials in acute kidney injury: Report from an NIDDK workshop on trial methodology

Palevsky, P. M., Molitoris, B., Okusa, M. D., Levin, A., Waikar, S. S., Wald, R., Chertow, G. M., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Faubel, S. G., Kellum, J. A., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 844-850 7 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Acute Kidney Injury
Clinical Trials
Education
Sample Size
32 Citations (Scopus)

Design of clinical trials in acute kidney injury: A report from an NIDDK workshop-prevention trials

Okusa, M. D., Molitoris, B., Palevsky, P. M., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Faubel, S., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T. H., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 851-855 5 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Acute Kidney Injury
Clinical Trials
Education
Mortality
27 Citations (Scopus)

Design of clinical trials in AKI: A report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings

Molitoris, B., Okusa, M. D., Palevsky, P. M., Chawla, L. S., Kaufman, J. S., Devarajan, P., Toto, R. M., Hsu, C. Y., Greene, T. H., Faubel, S. G., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chinchilli, V. M. & 15 others, Liu, K. D., Cheung, A. K., Weisbord, S. D., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 856-860 5 p.

Research output: Contribution to journalArticle

National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Sepsis
Clinical Trials
Education
Wounds and Injuries
58 Citations (Scopus)

Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified delphi process

Kellum, J. A., Mehta, R. L., Levin, A., Molitoris, B., Warnock, D. G., Shah, S. V., Joannidis, M. & Ronco, C., May 2008, In : Clinical Journal of the American Society of Nephrology. 3, 3, p. 887-894 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Research
Developed Countries
Translational Medical Research
Developing Countries

Dialytic care of patients with acute renal failure

Yaqub, M. & Molitoris, B., Jan 2000, In : Drugs of Today. 36, 1, p. 13-24 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Renal Replacement Therapy
Patient Care
Dialysis
Membranes
39 Citations (Scopus)
Cell Polarity
Pathologic Processes
Actin Cytoskeleton
Cell Biology
Epithelium

Disease-specific kidney imaging: Introduction

Molitoris, B., May 2011, In : Seminars in Nephrology. 31, 3, p. 235-236 2 p.

Research output: Contribution to journalArticle

Kidney Diseases
Diagnostic Imaging
123 Citations (Scopus)

Dissociation and redistribution of Na+,K+-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion

Molitoris, B., Geerdes, A. & McIntosh, J. R., Aug 1991, In : Journal of Clinical Investigation. 88, 2, p. 462-469 8 p.

Research output: Contribution to journalArticle

Actins
Adenosine Triphosphate
Membranes
Actin Cytoskeleton
Detergents
1 Citation (Scopus)

DNA damage response protects against progressive kidney disease

Molitoris, B. A., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4574-4575 2 p.

Research output: Contribution to journalReview article

Kidney Diseases
DNA Damage
Wounds and Injuries
G2 Phase Cell Cycle Checkpoints
Acute Kidney Injury
19 Citations (Scopus)

Dynamic multiphoton microscopy: Focusing light on acute kidney injury

Hall, A. M. & Molitoris, B., Sep 1 2014, In : Physiology. 29, 5, p. 334-342 9 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Microscopy
Light
Rodentia
Kidney
21 Citations (Scopus)

Early monitoring of acute tubular necrosis in the rat kidney by 23Na-MRI

Atthe, B. K., Babsky, A. M., Hopewell, P. N., Phillips, C., Molitoris, B. & Bansal, N., Nov 2009, In : American Journal of Physiology - Renal Physiology. 297, 5

Research output: Contribution to journalArticle

Necrosis
Sodium
Magnetic Resonance Imaging
Ischemia
Kidney
choline oxidase
Choline
Methionine
Liver
16 Citations (Scopus)

Effect of Human Recombinant Alkaline Phosphatase on 7-Day Creatinine Clearance in Patients with Sepsis-Associated Acute Kidney Injury: A Randomized Clinical Trial

Pickkers, P., Mehta, R. L., Murray, P. T., Joannidis, M., Molitoris, B. A., Kellum, J. A., Bachler, M., Hoste, E. A. J., Hoiting, O., Krell, K., Ostermann, M., Rozendaal, W., Valkonen, M., Brealey, D., Beishuizen, A., Meziani, F., Murugan, R., De Geus, H., Payen, D., Van Den Berg, E. & 1 others, Arend, J., Jan 1 2018, (Accepted/In press) In : JAMA - Journal of the American Medical Association.

Research output: Contribution to journalArticle

Acute Kidney Injury
Alkaline Phosphatase
Creatinine
Sepsis
Randomized Controlled Trials
113 Citations (Scopus)

Effect of reversible ATP depletion on tight-junction integrity in LLC-PK1 cells

Ellen Canfield, P., Geerdes, A. M. & Molitoris, B., 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 6 30-6

Research output: Contribution to journalArticle

LLC-PK1 Cells
Tight Junctions
Adenosine Triphosphate
Mannitol
Antimycin A
18 Citations (Scopus)

Effects of biomechanical forces on signaling in the cortical collecting duct (CCD)

Carrisoza-Gaytan, R., Liu, Y., Flores, D., Else, C., Lee, H. G., Rhodes, G., Sandoval, R. M., Kleyman, T. R., Lee, F. Y. I., Molitoris, B., Satlin, L. M. & Rohatgi, R., Jul 15 2014, In : American Journal of Physiology - Renal Physiology. 307, 2

Research output: Contribution to journalArticle

Dinoprostone
Cations
Paracrine Communication
Collagen Type IV
Furosemide
11 Citations (Scopus)

Effects of glucose and parathyroid hormone on the renal handling of myoinositol by isolated perfused dog kidneys

Molitoris, B., Hruska, K. A., Fishman, N. & Daughaday, W. H., 1979, In : Journal of Clinical Investigation. 63, 6, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

Inositol
Parathyroid Hormone
Dogs
Kidney
Glucose

Effects of parathyroid hormone (PTH) on renal myo inositol (MI) metabolism. Relationship to ion transport

Molitoris, B., Hruska, K. A. & Daughaday, W. H., 1977, In : Clinical Research. 25, 3

Research output: Contribution to journalArticle

Ion Transport
Inositol
Parathyroid Hormone
Kidney
18 Citations (Scopus)

Effects of vitamin D-induced chronic hypercalcemia on rat renal cortical plasma membranes and mitochondria

Levi, M., Molitoris, B., Burke, T. J., Schrier, R. W. & Simon, F. R., 1987, American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 2 ed. Vol. 252.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypercalcemia
Vitamin D
Mitochondria
Cell Membrane
Kidney
27 Citations (Scopus)

Efficacy of intramuscular and intraperitoneal deferoxamine for aluminium chelation

Molitoris, B., Alfrey, P. S., Miller, N. L., Hasbargen, J. A., Kaehney, W. D. & Smith, B. J., 1987, In : Kidney International. 31, 4, p. 986-991 6 p.

Research output: Contribution to journalArticle

Deferoxamine
Aluminum
Renal Dialysis
Serum
Continuous Ambulatory Peritoneal Dialysis
245 Citations (Scopus)

Endothelial injury and dysfunction: Role in the extension phase of acute renal failure

Molitoris, B. A. & Sutton, T. A., Aug 2004, In : Kidney International. 66, 2, p. 496-499 4 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Wounds and Injuries
Blood Vessels
Endothelial Cells
92 Citations (Scopus)

Endothelial injury and dysfunction in ischemic acute renal failure

Molitoris, B., Sandoval, R. & Sutton, T., 2002, In : Critical Care Medicine. 30, 5 SUPPL.

Research output: Contribution to journalArticle

Acute Kidney Injury
Endothelial Cells
Wounds and Injuries
Actins
P-Selectin
56 Citations (Scopus)
Ischemia
Membranes
Membrane Lipids
Glucose
Membrane Proteins

Erratum

Molitoris, B. & Simon, F. R., Oct 1986, In : Journal of Membrane Biology. 94, 3, p. 300 1 p.

Research output: Contribution to journalArticle

26 Citations (Scopus)

Erythropoietin requirements increase following hospitalization in end-stage renal disease patients

Yaqub, M., Leiser, J. & Molitoris, B., 2001, In : American Journal of Nephrology. 21, 5, p. 390-396 7 p.

Research output: Contribution to journalArticle

Erythropoietin
Chronic Kidney Failure
Hemoglobins
Hospitalization
Renal Dialysis
1 Citation (Scopus)

Establishment of Polarity in Epithelial Cells of the Developing Nephron

Karp, S. & Molitoris, B., Mar 15 2003, The Kidney: From Normal Development to Congenital Disease. Elsevier Inc., p. 211-220 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nephrons
Epithelial Cells
Membranes
Scaffolds
Actins
88 Citations (Scopus)

Evaluation and initial management of acute kidney injury

Himmelfarb, J., Joannidis, M., Molitoris, B., Schietz, M., Okusa, M. D., Warnock, D., Laghi, F., Goldstein, S. L., Prielipp, R., Parikh, C. R., Pannu, N., Lobo, S. M., Shah, S., D'Intini, V. & Kellum, J. A., Jul 2008, In : Clinical Journal of the American Society of Nephrology. 3, 4, p. 962-967 6 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Biomarkers
Comorbidity
Mortality
6 Citations (Scopus)

Evolving basic concepts in ischemic injury

De Broe, M. E., Bonventre, J. V., Molitoris, B. & Haller, H., Aug 2004, In : Kidney International. 66, 2, p. 479 1 p.

Research output: Contribution to journalArticle

Wounds and Injuries
1 Citation (Scopus)

Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection

Kolb, A. L., Corridon, P. R., Zhang, S., Xu, W., Witzmann, F., Collett, J. A., Rhodes, G. J., Winfree, S., Bready, D., Pfeffenberger, Z. J., Pomerantz, J. M., Hato, T., Nagami, G. T., Molitoris, B., Basile, D., Atkinson, S. J. & Bacallao, R., Apr 1 2018, In : Journal of the American Society of Nephrology. 29, 4, p. 1154-1164 11 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Ischemic Preconditioning
Mitochondria
Cytoprotection
Wounds and Injuries
30 Citations (Scopus)
Acidosis
Actin Cytoskeleton
Actins
Adenosine Triphosphate
Ischemia

Fluorescent dextrans in intravital multi- photon microscopy

Sandoval, R. M. & Molitoris, B., Jan 1 2014, Advances in Intravital Microscopy: From Basic to Clinical Research. Springer Netherlands, p. 205-219 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dextrans
Photons
Microscopy
Kidney
Polymers

Fluorescent Imaging and Microscopy for Dynamic Processes in Rats

Sandoval, R. M., Molitoris, B. & Palygin, O., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 151-175 25 p. (Methods in Molecular Biology; vol. 2018).

Research output: Chapter in Book/Report/Conference proceedingChapter

Microscopy
Photons
Kidney
Genetically Modified Animals
Translational Medical Research
237 Citations (Scopus)

Functional studies of the kidney of living animals using multicolor two-photon microscopy

Dunn, K., Sandoval, R. M., Kelly, K., Dagher, P., Tanner, G. A., Atkinson, S. J., Bacallao, R. & Molitoris, B., Sep 2002, In : American Journal of Physiology - Cell Physiology. 283, 3 52-3

Research output: Contribution to journalArticle

Photons
Microscopy
Microscopic examination
Animals
Kidney

Further studies on the effect of parathyroid hormone (PTH) on myoinositol metabolism and ion transport

Hruska, K. A., Molitoris, B. & Meltzer, V., 1978, In : Kidney International. 14, 6, p. 741 1 p.

Research output: Contribution to journalArticle

Ion Transport
Inositol
Parathyroid Hormone
65 Citations (Scopus)

Gentamicin inhibits renal protein and phospholipid metabolism in rats: Implications involving intracellular trafficking

Sundin, D. P., Sandoval, R. & Molitoris, B., 2001, In : Journal of the American Society of Nephrology. 12, 1, p. 114-123 10 p.

Research output: Contribution to journalArticle

Gentamicins
Phospholipids
Kidney
Microvilli
Proteins
30 Citations (Scopus)
LLC-PK1 Cells
Golgi Apparatus
Gentamicins
Fluorescence
Aminoglycosides
72 Citations (Scopus)
Secretory Pathway
Aminoglycosides
Gentamicins
Endoplasmic Reticulum
Cytosol