Bruce Molitoris

  • 15617 Citations
  • 62 h-Index
1974 …2019
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Publications 1974 2019

  • 15617 Citations
  • 62 h-Index
  • 224 Article
  • 20 Chapter
  • 2 Editorial
  • 1 Review article

High pressure freezing and freeze substitution: Advances in renal research

Pennington, J. G., Miller, C. A., Sandoval, R., Gattone, V. H., Molitoris, B. & Bacallao, R., 2004, In : Microscopy and Microanalysis. 10, SUPPL. 2, p. 1226-1227 2 p.

Research output: Contribution to journalArticle

Freezing
freezing
Substitution reactions
substitutes
3 Citations (Scopus)

HWA-448 reduces gentamicin toxicity in LLC-PK1 cells

Ford, D. M., Thieme, R. E., Lamp, C. A., Covington, S. J. & Molitoris, B., 1995, In : Journal of Pharmacology and Experimental Therapeutics. 274, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

LLC-PK1 Cells
Gentamicins
Phospholipids
Cell Membrane
Enzymes
7 Citations (Scopus)

Hydrodynamic isotonic fluid delivery ameliorates moderate-to-severe ischemia-reperfusion injury in rat kidneys

Collett, J. A., Corridon, P. R., Mehrotra, P., Kolb, A. L., Rhodes, G. J., Miller, C. A., Molitoris, B., Pennington, J. G., Sandoval, R. M., Atkinson, S. J., Campos-Bilderback, S., Basile, D. & Bacallao, R., Jul 1 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2081-2092 12 p.

Research output: Contribution to journalArticle

Hydrodynamics
Reperfusion Injury
Kidney
Renal Veins
Wounds and Injuries
10 Citations (Scopus)

Illuminating mitochondrial function and dysfunction using multiphoton technology

Weinberg, J. M. & Molitoris, B., Jun 2009, In : Journal of the American Society of Nephrology. 20, 6, p. 1164-1166 3 p.

Research output: Contribution to journalArticle

Multiphoton Fluorescence Microscopy
Distal Kidney Tubule
Proximal Kidney Tubule
Mitochondria
Technology
15 Citations (Scopus)

Imaging techniques in acute kidney injury

Sharfuddin, A., Sandoval, R. M. & Molitoris, B., Sep 2008, In : Nephron - Clinical Practice. 109, 4

Research output: Contribution to journalArticle

Photons
Acute Kidney Injury
Microscopy
Research Personnel
Kidney
177 Citations (Scopus)

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury

Basile, D., Friedrich, J. L., Spahic, J., Knipe, N., Mang, H., Leonard, E. C., Changizi-Ashtiyani, S., Bacallao, R., Molitoris, B. & Sutton, T., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3

Research output: Contribution to journalArticle

Acute Kidney Injury
Blood Vessels
Endothelial Cells
Vascular Endothelial Growth Factor A
Bromodeoxyuridine
161 Citations (Scopus)

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

Russo, L. M., Sandoval, R. M., Campos-Bilderback, S., Molitoris, B., Comper, W. D. & Brown, D., Mar 2009, In : Journal of the American Society of Nephrology. 20, 3, p. 489-494 6 p.

Research output: Contribution to journalArticle

Albuminuria
Diabetic Nephropathies
Albumins
Proximal Kidney Tubule
Photons
13 Citations (Scopus)

Implications of a Nephrology Workforce Shortage for Dialysis Patient Care

Mehrotra, R., Shaffer, R. N. & Molitoris, B., May 2011, In : Seminars in Dialysis. 24, 3, p. 275-277 3 p.

Research output: Contribution to journalArticle

Nephrology
Dialysis
Patient Care
Vulnerable Populations
Health Policy
1 Citation (Scopus)
Acute Kidney Injury
Creatinine
Serum
Mortality
Urine
62 Citations (Scopus)

Improving outcomes from acute kidney injury

Molitoris, B., Levin, A., Warnock, D. G., Joannidis, M., Mehta, R. L., Kellum, J. A., Ronco, C. & Shah, S., Jul 2007, In : Journal of the American Society of Nephrology. 18, 7, p. 1992-1994 3 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
41 Citations (Scopus)

Improving outcomes from acute kidney injury: Report of an initiative

Bagga, A., Bakkaloglu, A., Devarajan, P., Mehta, R. L., Kellum, J. A., Shah, S. V., Molitoris, B., Ronco, C., Warnock, D. G., Joannidis, M. & Levin, A., Oct 2007, In : Pediatric Nephrology. 22, 10, p. 1655-1658 4 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Creatinine
Nephrology
Critical Care
85 Citations (Scopus)

Improving Outcomes From Acute Kidney Injury: Report of an Initiative

Levin, A., Warnock, D. G., Mehta, R. L., Kellum, J. A., Shah, S. V., Molitoris, B. & Ronco, C., Jul 2007, In : American Journal of Kidney Diseases. 50, 1, p. 1-4 4 p.

Research output: Contribution to journalArticle

International Cooperation
Acute Kidney Injury
Creatinine
41 Citations (Scopus)

Improving outcomes from acute kidney injury (AKI): Report on an initiative

Ronco, C., Levin, A., Warnock, D. G., Metha, R. L., Kellum, J. A., Shah, S. & Molitoris, B., May 2007, In : International Journal of Artificial Organs. 30, 5, p. 373-376 4 p.

Research output: Contribution to journalArticle

Pediatrics
Acute Kidney Injury
Nephrology
Critical Care
Patient Care
103 Citations (Scopus)

Improving outcomes of acute kidney injury: Report of an initiative

Molitoris, B., Levin, A., Warnock, D. G., Joannidis, M., Mehta, R. L., Kellum, J. A., Ronco, C. & Shah, S. V., Aug 2007, In : Nature Clinical Practice Nephrology. 3, 8, p. 439-442 4 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Renal Insufficiency
Creatinine
Serum
536 Citations (Scopus)

Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001

Xue, J. L., Daniels, F., Star, R. A., Kimmel, P. L., Eggers, P. W., Molitoris, B., Himmelfarb, J. & Collins, A. J., Apr 2006, In : Journal of the American Society of Nephrology. 17, 4, p. 1135-1142 8 p.

Research output: Contribution to journalArticle

Medicare
Acute Kidney Injury
Mortality
Incidence
Critical Care
20 Citations (Scopus)

Inherited diseases of the glomerular basement membrane

Bodziak, K. A., Hammond, W. S. & Molitoris, B., 1994, In : American Journal of Kidney Diseases. 23, 4, p. 605-618 14 p.

Research output: Contribution to journalArticle

Hereditary Nephritis
Glomerular Basement Membrane
Nail-Patella Syndrome
Hematuria
Kidney Transplantation
9 Citations (Scopus)

Inhibition of avb5 integrin attenuates vascular permeability and protects against renal ischemia-reperfusion injury

McCurley, A., Alimperti, S., Campos-Bilderback, S., Sandoval, R. M., Calvino, J. E., Reynolds, T. L., Quigley, C., Mugford, J. W., Polacheck, W. J., Gomez, I. G., Dovey, J., Marsh, G., Huang, A., Qian, F., Weinreb, P. H., Dolinski, B. M., Moore, S., Duffield, J. S., Chen, C. S., Molitoris, B. & 2 others, Violette, S. M. & Crackower, M. A., Jun 1 2017, In : Journal of the American Society of Nephrology. 28, 6, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

Capillary Permeability
Reperfusion Injury
Integrins
Kidney
Pericytes
235 Citations (Scopus)
Endothelium
Ischemia
Kidney
Wounds and Injuries
Acute Kidney Injury
5 Citations (Scopus)

Intravital imaging of the kidney in a rat model of salt-sensitive hypertension

Endres, B. T., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S., Kamocka, M., McDermott-Roe, C., Staruschenko, A., Molitoris, B., Geurts, A. M. & Palygin, O., Aug 1 2017, In : American Journal of Physiology - Renal Physiology. 313, 2, p. F163-F173

Research output: Contribution to journalArticle

Albuminuria
Salts
Albumins
Hypertension
Kidney
37 Citations (Scopus)

Intravital imaging of the kidney using multiparameter multiphoton microscopy.

Dunn, K., Sandoval, R. M. & Molitoris, B., 2003, In : Nephron - Experimental Nephrology. 94, 1

Research output: Contribution to journalArticle

Photons
Microscopy
Kidney
Animal Structures
Endocytosis
4 Citations (Scopus)

Intravital multiphoton microscopy as a tool for studying renal physiology and pathophysiology

Sandoval, R. M. & Molitoris, B., 2017, (Accepted/In press) In : Methods.

Research output: Contribution to journalArticle

Physiology
Photons
Microscopy
Microscopic examination
Kidney
135 Citations (Scopus)

Intravital multiphoton microscopy of dynamic renal processes

Molitoris, B. & Sandoval, R. M., Jun 2005, In : American Journal of Physiology - Renal Physiology. 288, 6 57-6

Research output: Contribution to journalArticle

Microscopy
Research Personnel
Kidney
Physiologic Monitoring
Endocytosis
30 Citations (Scopus)

Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models

Imamura, R., Isaka, Y., Sandoval, R. M., Ori, A., Adamsky, S., Feinstein, E., Molitoris, B. & Takahara, S., 2010, In : Cell Transplantation. 19, 12, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

Photons
Kidney Transplantation
Small Interfering RNA
Rats
Microscopy
85 Citations (Scopus)

In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury

Hall, A. M., Rhodes, G. J., Sandoval, R. M., Corridon, P. R. & Molitoris, B., Jan 2013, In : Kidney International. 83, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Ischemia
Mitochondrial Membrane Potential
NAD
13 Citations (Scopus)

Ironing Out the Pathogenesis of Acute Kidney Injury

Hingorani, S., Molitoris, B. & Himmelfarb, J., Apr 2009, In : American Journal of Kidney Diseases. 53, 4, p. 569-571 3 p.

Research output: Contribution to journalArticle

Proto-Oncogene Proteins
Antimicrobial Cationic Peptides
Alpha-Globulins
Lipocalins
beta 2-Microglobulin
79 Citations (Scopus)

Ischemia activates actin depolymerizing factor: Role in proximal tubule microvillar actin alterations

Schwartz, N., Hosford, M., Sandoval, R. M., Wagner, M., Atkinson, S. J., Bamburg, J. & Molitoris, B., Apr 1999, In : American Journal of Physiology - Renal Physiology. 276, 4 45-4

Research output: Contribution to journalArticle

Destrin
Actins
Ischemia
Microvilli
Actin Cytoskeleton
138 Citations (Scopus)
Actin Cytoskeleton
Ischemia
Membranes
Membrane Proteins
Membrane Lipids
114 Citations (Scopus)

Ischemia-induced loss of epithelial polarity. Role of the tight junction

Molitoris, B., Falk, S. A. & Dahl, R. H., 1989, In : Journal of Clinical Investigation. 84, 4, p. 1334-1339 6 p.

Research output: Contribution to journalArticle

Tight Junctions
Ischemia
Membranes
Ruthenium Red
Lipids
1 Citation (Scopus)

Ischemia-induced tight junction dysfunction in the kidney

Marrs, J. A. & Molitoris, B., Jan 1 2001, Tight Junctions. CRC Press, p. 533-552 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tight Junctions
Ischemia
Epithelial Cells
Waste Products
Kidney
57 Citations (Scopus)
Actin Cytoskeleton
Vascular Smooth Muscle
Smooth Muscle Myocytes
Ischemia
Actins
55 Citations (Scopus)

Ischemia induces partial loss of surface membrane polarity and accumulation of putative calcium ionophores

Molitoris, B., Wilson, P. D., Schrier, R. W. & Simon, F. R., 1985, In : Journal of Clinical Investigation. 76, 6, p. 2097-2105 9 p.

Research output: Contribution to journalArticle

Calcium Ionophores
Ischemia
Adenosine Triphosphatases
Membranes
Leucyl Aminopeptidase
63 Citations (Scopus)

Ischemia induces surface membrane dysfunction: Mechanism of altered Na+-dependent glucose transport

Molitoris, B. & Kinne, R., 1987, In : Journal of Clinical Investigation. 80, 3, p. 647-654 8 p.

Research output: Contribution to journalArticle

Microvilli
Ischemia
Glucose
Membranes
Phlorhizin
18 Citations (Scopus)

Ischemic acute renal failure: Exciting times at our fingertips

Molitoris, B., 1998, In : Current Opinion in Nephrology and Hypertension. 7, 4, p. 405-406 2 p.

Research output: Contribution to journalArticle

Growth Substances
alpha-MSH
Calcium-Calmodulin-Dependent Protein Kinases
Heat-Shock Proteins
Acute Kidney Injury
49 Citations (Scopus)

Ischemic injury induces ADF relocalization to the apical domain of rat proximal tubule cells

Ashworth, S. L., Sandoval, R. M., Hosford, M., Hamburg, J. R. & Molitoris, B., May 2001, In : American Journal of Physiology - Renal Physiology. 280, 5 49-5

Research output: Contribution to journalArticle

Destrin
Ischemia
Wounds and Injuries
Actins
Microvilli
50 Citations (Scopus)

Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1

Wagner, M., Rhodes, G., Wang, E., Pruthi, V., Arif, E., Saleem, M. A., Wean, S. E., Garg, P., Verma, R., Holzman, L. B., Gattone, V., Molitoris, B. & Nihalani, D., Dec 19 2008, In : Journal of Biological Chemistry. 283, 51, p. 35579-35589 11 p.

Research output: Contribution to journalArticle

Podocytes
Diaphragms
Diaphragm
Kidney
Ischemia
10 Citations (Scopus)

Kidney endothelial dysfunction: Ischemia, localized infections and sepsis

Molitoris, B. & Sandoval, R. M., Sep 2011, Contributions to Nephrology. Vol. 174. p. 108-118 11 p. (Contributions to Nephrology; vol. 174).

Research output: Chapter in Book/Report/Conference proceedingChapter

Sepsis
Leukocytes
Ischemia
Kidney
Endothelial Cells

Kidney Mentoring and Assessment Program for Students: A guide for engaging medical students in nephrology

Bayliss, G. P., Cobb, J., Decker, B., Hellman, R., Vasavada, N., MacKelaite, L., Shadur, C., Ilori, T., Ibrahim, T., Leight, K., Hsiao, L. L., Molitoris, B. A., Okusa, M. D. & Parker, M. G., Feb 25 2019, In : Clinical Kidney Journal. 12, 6, p. 761-766 6 p.

Research output: Contribution to journalArticle

Open Access
Nephrology
Medical Students
Students
Kidney
Kidney Diseases
3 Citations (Scopus)
vanadium
tin
nickel
chromium
chicks
12 Citations (Scopus)

Lessons from Haiti on disaster relief

Portilla, D., Shaffer, R. N., Okusa, M. D., Mehrotra, R., Molitoris, B., Bunchman, T. E. & Ibrahim, T., Nov 1 2010, In : Clinical Journal of the American Society of Nephrology. 5, 11, p. 2122-2129 8 p.

Research output: Contribution to journalArticle

Organizational Objectives
Disaster Medicine
Disaster Planning
Haiti
International Cooperation
6 Citations (Scopus)
Microscopy
Albumins
Permeability
56 Citations (Scopus)

Loss of epithelial polarity: A novel hypothesis for reduced proximal tubule Na+ transport following ischemic injury

Molitoris, B., Chan, L. K., Shapiro, J. I., Conger, J. D. & Falk, S. A., Feb 1989, In : Journal of Membrane Biology. 107, 2, p. 119-127 9 p.

Research output: Contribution to journalArticle

Membranes
Ischemia
Wounds and Injuries
Adenosine Triphosphatases
Proximal Kidney Tubule
11 Citations (Scopus)
Protein Transport
Vacuoles
Gentamicins
Saccharomyces cerevisiae
Yeasts
8 Citations (Scopus)

Maintenance of epithelial surface membrane lipid polarity: A role for differing phospholipid translocation rates

Molitoris, B. & Simon, F. R., Feb 1986, In : Journal of Membrane Biology. 94, 1, p. 47-53 7 p.

Research output: Contribution to journalArticle

Membrane Lipids
Phospholipids
Maintenance
Membranes
Microvilli
1 Citation (Scopus)

Managing conflicts of interest: The road ahead

Stokes, J. B., Berns, A. S., Henrich, W. L., McKinney, T. D., Molitoris, B. & Palmer, B. F., Sep 2009, In : Journal of the American Society of Nephrology. 20, 9, p. 1860-1862 3 p.

Research output: Contribution to journalArticle

Organizational Policy
Conflict of Interest
Nephrology
Medical Societies
65 Citations (Scopus)

Markedly increased clearance of vancomycin during hemodialysis using polysulfone dialyzers

Lanese, D. M., Alfrey, P. S. & Molitoris, B., 1989, In : Kidney International. 35, 6, p. 1409-1412 4 p.

Research output: Contribution to journalArticle

Vancomycin
Renal Dialysis
polysulfone P 1700
7 Citations (Scopus)

Measuring glomerular filtration rate in acute kidney injury: Yes, but not yet

Molitoris, B., Sep 24 2012, In : Critical Care. 16, 5, 158.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Acute Kidney Injury
Biomarkers
Critical Care
Creatinine
19 Citations (Scopus)

Measuring glomerular filtration rate in the intensive care unit: No substitutes please

Molitoris, B., Sep 4 2013, In : Critical Care. 17, 5, 181.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Acute Kidney Injury
Intensive Care Units
Chronic Renal Insufficiency
Creatinine
84 Citations (Scopus)

Mechanism of Actin Polymerization in Cellular ATP Depletion

Atkinson, S. J., Hosford, M. A. & Molitoris, B., Feb 13 2004, In : Journal of Biological Chemistry. 279, 7, p. 5194-5199 6 p.

Research output: Contribution to journalArticle

Polymerization
Actins
Adenosine Triphosphate
Thymosin
Profilins
9 Citations (Scopus)

Mechanism of increased clearance of glycated albumin by proximal tubule cells

Wagner, M., Myslinski, J., Pratap, S., Flores, B., Rhodes, G., Campos-Bilderback, S., Sandoval, R. M., Kumar, S., Patel, M., Ashish & Molitoris, B., May 15 2016, In : American Journal of Physiology - Renal Physiology. 310, 10, p. F1089-F1102

Research output: Contribution to journalArticle

Albumins
Transcytosis
glycosylated serum albumin
Proximal Kidney Tubule
Serum Albumin
32 Citations (Scopus)

Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells

Molitoris, B., Meyer, C., Dahl, R. & Geerdes, A., May 1993, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 264, 5 33-5

Research output: Contribution to journalArticle

Aminoglycosides
Gentamicins
Ischemia
Membranes
Phosphatidylinositols