Bruce Molitoris

  • 15549 Citations
  • 62 h-Index
1974 …2019
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Publications 1974 2019

  • 15549 Citations
  • 62 h-Index
  • 223 Article
  • 20 Chapter
  • 2 Editorial
  • 1 Review article
54 Citations (Scopus)

Membrane adsorption of β2-microglobulin: Equilibrium and kinetic characterization

Clark, W. R., Macias, W. L., Molitoris, B. & Wang, N. H. L., Oct 1994, In : Kidney International. 46, 4, p. 1140-1146 7 p.

Research output: Contribution to journalArticle

Adsorption
Membranes
Amyloidosis
Dialysis
Buffers
17 Citations (Scopus)

Membrane fluidity: measurement and relationship to solute transport.

Molitoris, B., Mar 1987, In : Seminars in Nephrology. 7, 1, p. 61-71 11 p.

Research output: Contribution to journalArticle

Biological Transport
Kidney Cortex
Membrane Fluidity
Fluorescence Polarization
Membrane Lipids
36 Citations (Scopus)

Micropuncture gene delivery and intravital two-photon visualization of protein expression in rat kidney

Tanner, G. A., Sandoval, R. M., Molitoris, B., Bamburg, J. R. & Ashworth, S. L., Sep 2005, In : American Journal of Physiology - Renal Physiology. 289, 3 58-3

Research output: Contribution to journalArticle

Green Fluorescent Proteins
Photons
Punctures
Kidney
Genes

Microscopy as a quantitative science

Molitoris, B., Jul 2005, In : International Journal of Artificial Organs. 28, 7, p. 663-665 3 p.

Research output: Contribution to journalArticle

Microscopic examination
387 Citations (Scopus)

Microvascular endothelial injury and dysfunction during ischemic acute renal failure

Sutton, T., Fisher, C. J. & Molitoris, B., 2002, In : Kidney International. 62, 5, p. 1539-1549 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Wounds and Injuries
Blood Vessels
Endothelial Cells
19 Citations (Scopus)

Mild ischemia predisposes the S3 segment to gentamicin toxicity

Spiegel, D. M., Shanley, P. F. & Molitoris, B., Sep 1990, In : Kidney International. 38, 3, p. 459-464 6 p.

Research output: Contribution to journalArticle

Gentamicins
Ischemia
Kidney
Creatinine
Inulin
11 Citations (Scopus)

Multiphoton imaging techniques in acute kidney injury

Molitoris, B. & Sandoval, R. M., Apr 2010, Contributions to Nephrology. Vol. 165. p. 46-53 8 p. (Contributions to Nephrology; vol. 165).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Kidney Injury
Microscopy
Research Personnel
Kidney
Wounds and Injuries
1 Citation (Scopus)

Multi-photon microscopy: Linking drug mechanism to disease physiology

Grinnell, B. W., Gupta, A., Sandoval, R. M. & Molitoris, B., Nov 2007, In : American Pharmaceutical Review. 10, 6

Research output: Contribution to journalArticle

Photons
Microscopy
Pharmaceutical Preparations
Physiological Phenomena
Preclinical Drug Evaluations
11 Citations (Scopus)

Multiphoton microscopy applied for real-time intravital imaging of bacterial infections in vivo

Choong, F. X., Sandoval, R. M., Molitoris, B. & Richter-Dahlfors, A., 2012, In : Methods in Enzymology. 506, p. 35-61 27 p.

Research output: Contribution to journalArticle

Bacterial Infections
Microscopy
Microscopic examination
Imaging techniques
Infection
62 Citations (Scopus)

Multiple factors influence glomerular albumin permeability in rats

Sandoval, R. M., Wagner, M., Patel, M., Campos-Bilderback, S., Rhodes, G. J., Wang, E., Wean, S. E., Clendenon, S. S. & Molitoris, B., Mar 2012, In : Journal of the American Society of Nephrology. 23, 3, p. 447-457 11 p.

Research output: Contribution to journalArticle

Albumins
Permeability
Wistar Rats
Microscopy
Transcytosis
23 Citations (Scopus)

Myo-inositol uptake by rat cultured inner medullary collecting tubule cells: Effect of osmolality

Veis, J. H., Molitoris, B., Teitelbaum, I., Mansour, J. A. & Berl, T., 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 260, 5 29-5

Research output: Contribution to journalArticle

Inositol
Osmolar Concentration
Cycloheximide
Nocodazole
Osmoregulation
61 Citations (Scopus)
Adenosine Triphosphatases
Adenosine Triphosphate
Ouabain
Membranes
LLC-PK1 Cells
11 Citations (Scopus)

Nephrology research - The past, present and future

Floege, J., Mak, R. H., Molitoris, B., Remuzzi, G. & Ronco, P., Nov 1 2015, In : Nature Reviews Nephrology. 11, 11, p. 677-687 11 p.

Research output: Contribution to journalArticle

Nephrology
Research
Atypical Hemolytic Uremic Syndrome
58 Citations (Scopus)

New insights into the cell biology of ischemic acute renal failure

Molitoris, B., 1991, In : Journal of the American Society of Nephrology. 1, 12, p. 1263-1270 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Cell Biology
Membranes
Membrane Proteins
Membrane Lipids
58 Citations (Scopus)

Newly developed techniques to study and diagnose acute renal failure

Dagher, P., Herget-Rosenthal, S., Ruehm, S. G., Jo, S. K., Star, R. A., Agarwal, R. & Molitoris, B., Aug 1 2003, In : Journal of the American Society of Nephrology. 14, 8, p. 2188-2198 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Animal Models
Magnetic Resonance Imaging
Renal Circulation
Regional Blood Flow
7 Citations (Scopus)

Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1 cells

Sandoval, R. M., Bacallao, R., Dunn, K., Leiser, J. D. & Molitoris, B., Dec 1 2002, In : American Journal of Physiology - Renal Physiology. 283, 6 52-6

Research output: Contribution to journalArticle

LLC-PK1 Cells
Golgi Apparatus
Gentamicins
Nucleotides
trans-Golgi Network
14 Citations (Scopus)

Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy

Hörbelt, M., Wotzlaw, C., Sutton, T., Molitoris, B., Philipp, T., Kribben, A., Fandrey, J. & Pietruck, F., Aug 2007, In : Kidney International. 72, 4, p. 422-429 8 p.

Research output: Contribution to journalArticle

Photons
Cations
Microscopy
Fluorescence
Kidney

Parathyroid hormone (PTH) induced turnover of myoinositol in isolated perfused dog kidneys

Hruska, K. A., Molitoris, B. & Daughaday, W. H., 1976, In : Kidney International. 10, 6, p. 490 1 p.

Research output: Contribution to journalArticle

Inositol
Parathyroid Hormone
Dogs
Kidney
30 Citations (Scopus)

Pathophysiology and functional significance of apical membrane disruption during ischemia

Ashworth, S. L. & Molitoris, B., 1999, In : Current Opinion in Nephrology and Hypertension. 8, 4, p. 449-458 10 p.

Research output: Contribution to journalArticle

Destrin
Actin Depolymerizing Factors
Ischemia
Actins
Membranes
1 Citation (Scopus)

Pathophysiology of Acute Kidney Injury

Molitoris, B. & Sharfuddin, A., 2013, Seldin and Geibisch's The Kidney. Elsevier Inc., Vol. 2. p. 2527-2575 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Kidney Injury
1 Citation (Scopus)

Pathophysiology of Acute Kidney Injury

Sharfuddin, A. & Molitoris, B., 2008, Seldin and Giebisch's The Kidney. Elsevier Inc., p. 2143-2191 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

323 Citations (Scopus)

Pathophysiology of ischemic acute kidney injury

Sharfuddin, A. & Molitoris, B., Apr 2011, In : Nature Reviews Nephrology. 7, 4, p. 189-200 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Ischemia
Chronic Renal Insufficiency
Wounds and Injuries
Cell Communication
24 Citations (Scopus)

Pharmacophotonics: Utilizing multi-photon microscopy to quantify drug delivery and intracellular trafficking in the kidney

Molitoris, B. & Sandoval, R. M., Oct 31 2006, In : Advanced Drug Delivery Reviews. 58, 7, p. 809-823 15 p.

Research output: Contribution to journalArticle

Photons
Microscopy
Kidney
Drug Trafficking
Research Personnel
65 Citations (Scopus)

Plasma protein adsorption to highly permeable hemodialysis membranes

Clark, W. R., Macias, W. L., Molitoris, B. & Wang, N. H. L., 1995, In : Kidney International. 48, 2, p. 481-488 8 p.

Research output: Contribution to journalArticle

Adsorption
Renal Dialysis
Blood Proteins
Membranes
Bovine Serum Albumin

Practical Considerations of Renal Biopsies in Critical Care Patients

Modi, J. R., Liapis, H., Molitoris, B. A. & Eadon, M. T., Dec 6 2017, Critical Care Nephrology: Third Edition. Elsevier Inc., p. 167-173.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

Critical Care
Kidney
Biopsy
Disease Management
Acute Kidney Injury
25 Citations (Scopus)

Progression of bacterial infections studied in real time -novel perspectives provided by multiphoton microscopy

Månsson, L. E., Melican, K., Molitoris, B. & Richter-Dahlfors, A., Oct 2007, In : Cellular Microbiology. 9, 10, p. 2334-2343 10 p.

Research output: Contribution to journalArticle

Bacterial Infections
Microscopy
Microscopic examination
Imaging techniques
Pathogens
1 Citation (Scopus)

Protective vascular coagulation in response to bacterial infection of the kidney is regulated by bacterial lipid A and host CD147

Schulz, A., Chuquimia, O. D., Antypas, H., Steiner, S. E., Sandoval, R. M., Tanner, G. A., Molitoris, B., Richter-Dahlfors, A. & Melican, K., Nov 1 2018, In : Pathogens and Disease. 76, 8, fty087.

Research output: Contribution to journalArticle

Lipid A
Bacterial Infections
Blood Vessels
Uropathogenic Escherichia coli
Kidney
37 Citations (Scopus)

Proximal tubules have the capacity to regulate uptake of albumin

Wagner, M., Campos-Bilderback, S., Chowdhury, M., Flores, B., Lai, X., Myslinski, J., Pandit, S., Sandoval, R. M., Wean, S. E., Wei, Y., Satlin, L. M., Wiggins, R. C., Witzmann, F. & Molitoris, B., Feb 1 2016, In : Journal of the American Society of Nephrology. 27, 2, p. 482-494 13 p.

Research output: Contribution to journalArticle

Albumins
Serum Albumin
Albumin Receptors
Proteins
Angiopoietin-2
74 Citations (Scopus)
Actin Cytoskeleton
Actins
Microfilament Proteins
Cell Polarity
Proteins
14 Citations (Scopus)
Actin Cytoskeleton
Actins
Cell Polarity
Proteins
Exocytosis
Actin Cytoskeleton
Actins
Cell Polarity
Proteins
Exocytosis
4 Citations (Scopus)

Quantifying dynamic kidney processes utilizing multi-photon microscopy

Molitoris, B. & Sandoval, R. M., 2007, Contributions to Nephrology. Vol. 156. p. 227-235 9 p. (Contributions to Nephrology; vol. 156).

Research output: Chapter in Book/Report/Conference proceedingChapter

Photons
Microscopy
Research Personnel
Kidney
Technology
20 Citations (Scopus)

Quantifying endocytosis in vivo using intravital two-photon microscopy

Sandoval, R. M. & Molitoris, B., 2008, Methods in Molecular Biology. Humana Press, Vol. 440. p. 389-402 14 p. (Methods in Molecular Biology; vol. 440).

Research output: Chapter in Book/Report/Conference proceedingChapter

Endocytosis
Photons
Microscopy
Research Personnel
Proximal Kidney Tubule
20 Citations (Scopus)

Quantifying Glomerular Filtration Rates in Acute Kidney Injury: A Requirement for Translational Success

Molitoris, B. & Reilly, E. S., 2016, (Accepted/In press) In : Seminars in Nephrology.

Research output: Contribution to journalArticle

Glomerular Filtration Rate
Acute Kidney Injury
Kidney
Nephrology
Wounds and Injuries
16 Citations (Scopus)
Macromolecules
Photons
Wistar Rats
Rats
Microscopy
44 Citations (Scopus)

Quantitative intravital microscopy using a Generalized Polarity concept for kidney studies

Yu, W., Sandoval, R. M. & Molitoris, B., Nov 2005, In : American Journal of Physiology - Cell Physiology. 289, 5 58-5

Research output: Contribution to journalArticle

Dextrans
Kidney
Bowman Capsule
Rats
Capsules
74 Citations (Scopus)
Optical Imaging
Kidney
Glomerular Filtration Rate
Fluorescent Dyes
Animal Models
31 Citations (Scopus)
Glomerular Filtration Rate
Acute Kidney Injury
Dextrans
Photons
Kidney
23 Citations (Scopus)

Rapid removal of DFO-chelated aluminum during hemodialysis using polysulfone dialyzers

Molitoris, B., Alfrey, A. C., Alfrey, P. S. & Miller, N. L., 1988, In : Kidney International. 34, 1, p. 98-101 4 p.

Research output: Contribution to journalArticle

Deferoxamine
Aluminum
Renal Dialysis
polysulfone P 1700
Dialysis
66 Citations (Scopus)

Real-time studies of the progression of bacterial infections and immediate tissue responses in live animals

Månsson, L. E., Melican, K., Boekel, J., Sandoval, R. M., Hautefort, I., Tanner, G. A., Molitoris, B. & Richter-dahlfors, A., Feb 2007, In : Cellular Microbiology. 9, 2, p. 413-424 12 p.

Research output: Contribution to journalArticle

Time and motion study
Time and Motion Studies
Bacterial Infections
Animals
Microdissection

Recovery of the actin cytoskeleton during cellular repair is independent of protein synthesis

Hosford, M., Sandoval, R. & Molitoris, B., 1996, In : Journal of Investigative Medicine. 44, 1

Research output: Contribution to journalArticle

Actin Cytoskeleton
Actins
Repair
Recovery
Proteins
23 Citations (Scopus)

Recruiting the Next Generation of Nephrologists

Parker, M. G., Pivert, K. A., Ibrahim, T. & Molitoris, B., Jul 2013, In : Advances in Chronic Kidney Disease. 20, 4, p. 326-335 10 p.

Research output: Contribution to journalArticle

Nephrology
Kidney Diseases
Physicians
Research
Quality of Life
1 Citation (Scopus)

Removal of Vancomycin by Hemodialysis: A Significant and Overlooked Consideration

Lanese, D. M. & Molitoris, B., 1989, In : Seminars in Dialysis. 2, 2, p. 73-74 2 p.

Research output: Contribution to journalEditorial

Vancomycin
Renal Dialysis
60 Citations (Scopus)

Renal apical membrane cholesterol and fluidity in regulation of phosphate transport

Molitoris, B., Alfrey, A. C., Harris, R. A. & Simon, F. R., 1985, American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 1 ed. Vol. 18.

Research output: Chapter in Book/Report/Conference proceedingChapter

Membrane Fluidity
Phosphates
Cholesterol
Kidney
Membranes
20 Citations (Scopus)

Renal blood flow in sepsis: A complex issue

Molitoris, B., Aug 2005, In : Critical Care. 9, 4, p. 327-328 2 p.

Research output: Contribution to journalArticle

Renal Circulation
Acute Kidney Injury
Sepsis
Microvessels
Endothelium
101 Citations (Scopus)

Renal cortical brush-border and basolateral membranes: Cholesterol and phospholipid Composition and relative turnover

Molitoris, B. & Simon, F. R., Oct 1985, In : Journal of Membrane Biology. 83, 3, p. 207-215 9 p.

Research output: Contribution to journalArticle

Microvilli
Phospholipids
Cholesterol
Kidney
Membranes
66 Citations (Scopus)

Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): A randomised clinical trial

de Zeeuw, D., Anzalone, D. A., Cain, V. A., Cressman, M. D., Heerspink, H. J. L., Molitoris, B., Monyak, J. T., Parving, H. H., Remuzzi, G., Sowers, J. R. & Vidt, D. G., Mar 1 2015, In : The Lancet Diabetes and Endocrinology. 3, 3, p. 181-190 10 p.

Research output: Contribution to journalArticle

Randomized Controlled Trials
Kidney
Creatinine
Proteinuria
Urine
50 Citations (Scopus)

Renal Endothelial Injury and Microvascular Dysfunction in Acute Kidney Injury

Verma, S. K. & Molitoris, B., Jan 1 2015, In : Seminars in Nephrology. 35, 1, p. 96-107 12 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Wounds and Injuries
Endothelium
Ischemia
2 Citations (Scopus)

Renal endothelium

Molitoris, B., Jan 1 2007, Endothelial Biomedicine. Cambridge University Press, p. 1271-1277 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Endothelial cells
Endothelium
Kidney
Endothelial Cells
Color films
30 Citations (Scopus)

Renal epithelial polarity in health and disease

Wagner, M. & Molitoris, B., Feb 1999, In : Pediatric Nephrology. 13, 2, p. 163-170 8 p.

Research output: Contribution to journalArticle

Kidney
Health
Epithelial Cells
Polycystic Kidney Diseases
Membranes