Bruce Molitoris

  • 15900 Citations
  • 62 h-Index
1974 …2020

Research output per year

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Publications

Article

Effect of reversible ATP depletion on tight-junction integrity in LLC-PK1 cells

Canfield, P. E., Geerdes, A. M. & Molitoris, B. A., Dec 1 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 6 30-6, p. F1038-F1045

Research output: Contribution to journalArticle

113 Scopus citations

Effects of biomechanical forces on signaling in the cortical collecting duct (CCD)

Carrisoza-Gaytan, R., Liu, Y., Flores, D., Else, C., Lee, H. G., Rhodes, G., Sandoval, R. M., Kleyman, T. R., Lee, F. Y. I., Molitoris, B., Satlin, L. M. & Rohatgi, R., Jul 15 2014, In : American Journal of Physiology - Renal Physiology. 307, 2, p. F195-F204

Research output: Contribution to journalArticle

19 Scopus citations

Effects of glucose and parathyroid hormone on the renal handling of myoinositol by isolated perfused dog kidneys

Molitoris, B. A., Hruska, K. A., Fishman, N. & Daughaday, W. H., Jan 1 1979, In : Journal of Clinical Investigation. 63, 6, p. 1110-1118 9 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Effects of parathyroid hormone (PTH) on renal myo inositol (MI) metabolism. Relationship to ion transport

Molitoris, B. A., Hruska, K. A. & Daughaday, W. H., Jan 1 1977, In : Clinical Research. 25, 3, p. 395A

Research output: Contribution to journalArticle

Efficacy of intramuscular and intraperitoneal deferoxamine for aluminium chelation

Molitoris, B. A., Alfrey, P. S., Miller, N. L., Hasbargen, J. A., Kaehney, W. D. & Smith, B. J., Jan 1 1987, In : Kidney international. 31, 4, p. 986-991 6 p.

Research output: Contribution to journalArticle

Open Access
27 Scopus citations

Endothelial injury and dysfunction: Role in the extension phase of acute renal failure

Molitoris, B. A. & Sutton, T. A., Aug 2004, In : Kidney international. 66, 2, p. 496-499 4 p.

Research output: Contribution to journalArticle

251 Scopus citations

Endothelial injury and dysfunction in ischemic acute renal failure

Molitoris, B. A., Sandoval, R. & Sutton, T. A., May 23 2002, In : Critical care medicine. 30, 5 SUPPL., p. S235-S240

Research output: Contribution to journalArticle

92 Scopus citations

Epithelial polarity following ischemia: A requirement for normal cell function

Spiegel, D. M., Wilson, P. D. & Molitoris, B. A., Jan 1 1989, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 256, 3 (25/3), p. F430-F436

Research output: Contribution to journalArticle

56 Scopus citations

Erythropoietin requirements increase following hospitalization in end-stage renal disease patients

Yaqub, M. S., Leiser, J. & Molitoris, B. A., Dec 1 2001, In : American journal of nephrology. 21, 5, p. 390-396 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Evaluation and initial management of acute kidney injury

Himmelfarb, J., Joannidis, M., Molitoris, B., Schietz, M., Okusa, M. D., Warnock, D., Laghi, F., Goldstein, S. L., Prielipp, R., Parikh, C. R., Pannu, N., Lobo, S. M., Shah, S., D'Intini, V. & Kellum, J. A., Jul 1 2008, In : Clinical Journal of the American Society of Nephrology. 3, 4, p. 962-967 6 p.

Research output: Contribution to journalArticle

89 Scopus citations

Evolving basic concepts in ischemic injury

De Broe, M. E., Bonventre, J. V., Molitoris, B. A. & Haller, H., Aug 2004, In : Kidney international. 66, 2, 1 p.

Research output: Contribution to journalArticle

6 Scopus citations

Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection

Kolb, A. L., Corridon, P. R., Zhang, S., Xu, W., Witzmann, F., Collett, J. A., Rhodes, G. J., Winfree, S., Bready, D., Pfeffenberger, Z. J., Pomerantz, J. M., Hato, T., Nagami, G. T., Molitoris, B., Basile, D., Atkinson, S. J. & Bacallao, R., Apr 1 2018, In : Journal of the American Society of Nephrology. 29, 4, p. 1154-1164 11 p.

Research output: Contribution to journalArticle

1 Scopus citations
30 Scopus citations

Functional studies of the kidney of living animals using multicolor two-photon microscopy

Dunn, K. W., Sandoval, R. M., Kelly, K. J., Dagher, P. C., Tanner, G. A., Atkinson, S. J., Bacallao, R. L. & Molitoris, B. A., Sep 1 2002, In : American Journal of Physiology - Cell Physiology. 283, 3 52-3, p. C905-C916

Research output: Contribution to journalArticle

238 Scopus citations

Further studies on the effect of parathyroid hormone (PTH) on myoinositol metabolism and ion transport

Hruska, K. A., Molitoris, B. M. & Meltzer, V., Jan 1 1978, In : Kidney international. 14, 6, 1 p.

Research output: Contribution to journalArticle

Gentamicin inhibits renal protein and phospholipid metabolism in rats: Implications involving intracellular trafficking

Sundin, D. P., Sandoval, R. & Molitoris, B. A., Jan 30 2001, In : Journal of the American Society of Nephrology. 12, 1, p. 114-123 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Gentamicin traffics rapidly and directly to the Golgi complex in LLC-PK1 cells

Sandoval, R. M., Dunn, K. W. & Molitoris, B. A., Dec 7 2000, In : American Journal of Physiology - Renal Physiology. 279, 5 48-5, p. F884-F890

Research output: Contribution to journalArticle

30 Scopus citations
73 Scopus citations

High pressure freezing and freeze substitution: Advances in renal research

Pennington, J. G., Miller, C. A., Sandoval, R., Gattone, V. H., Molitoris, B. & Bacallao, R. L., Sep 24 2004, In : Microscopy and Microanalysis. 10, SUPPL. 2, p. 1226-1227 2 p.

Research output: Contribution to journalArticle

HWA-448 reduces gentamicin toxicity in LLC-PK1 cells

Ford, D. M., Thieme, R. E., Lamp, C. A., Covington, S. J. & Molitoris, B. A., Jan 1 1995, In : Journal of Pharmacology and Experimental Therapeutics. 274, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Hydrodynamic isotonic fluid delivery ameliorates moderate-to-severe ischemia-reperfusion injury in rat kidneys

Collett, J. A., Corridon, P. R., Mehrotra, P., Kolb, A. L., Rhodes, G. J., Miller, C. A., Molitoris, B. A., Pennington, J. G., Sandoval, R. M., Atkinson, S. J., Campos-Bilderback, S. B., Basile, D. P. & Bacallao, R. L., Jul 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2081-2092 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine

Liu, X. F., Wei, J., Zhou, Q., Molitoris, B. A., Sandoval, R., Kobayashi, H., Okada, R., Nagaya, T., Karim, B., Butcher, D. & Pastan, I., Mar 17 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6086-6091 6 p.

Research output: Contribution to journalArticle

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury

Basile, D. P., Friedrich, J. L., Spahic, J., Knipe, N., Mang, H., Leonard, E. C., Changizi-Ashtiyani, S., Bacallao, R. L., Molitoris, B. A. & Sutton, T. A., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3, p. F721-F733

Research output: Contribution to journalArticle

180 Scopus citations

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

Russo, L. M., Sandoval, R. M., Campos, S. B., Molitoris, B. A., Comper, W. D. & Brown, D., Mar 1 2009, In : Journal of the American Society of Nephrology. 20, 3, p. 489-494 6 p.

Research output: Contribution to journalArticle

163 Scopus citations

Improving outcomes from acute kidney injury (AKI): Report on an initiative

Ronco, C., Levin, A., Warnock, D. G., Metha, R. L., Kellum, J. A., Shah, S. & Molitoris, B. A., May 2007, In : International Journal of Artificial Organs. 30, 5, p. 373-376 4 p.

Research output: Contribution to journalArticle

42 Scopus citations

Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001

Xue, J. L., Daniels, F., Star, R. A., Kimmel, P. L., Eggers, P. W., Molitoris, B. A., Himmelfarb, J. & Collins, A. J., Apr 1 2006, In : Journal of the American Society of Nephrology. 17, 4, p. 1135-1142 8 p.

Research output: Contribution to journalArticle

543 Scopus citations

Inherited Diseases of the Glomerular Basement Membrane

Bodziak, K. A., Hammond, W. S. & Molitoris, B. A., Jan 1 1994, In : American Journal of Kidney Diseases. 23, 4, p. 605-618 14 p.

Research output: Contribution to journalArticle

20 Scopus citations

Inhibition of avb5 integrin attenuates vascular permeability and protects against renal ischemia-reperfusion injury

McCurley, A., Alimperti, S., Campos-Bilderback, S. B., Sandoval, R. M., Calvino, J. E., Reynolds, T. L., Quigley, C., Mugford, J. W., Polacheck, W. J., Gomez, I. G., Dovey, J., Marsh, G., Huang, A., Qian, F., Weinreb, P. H., Dolinski, B. M., Moore, S., Duffield, J. S., Chen, C. S., Molitoris, B. A. & 2 others, Violette, S. M. & Crackower, M. A., Jun 2017, In : Journal of the American Society of Nephrology. 28, 6, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Injury of the renal microvascular endothelium alters barrier function after ischemia

Sutton, T. A., Mang, H. E., Campos, S. B., Sandoval, R. M., Yoder, M. C. & Molitoris, B. A., Aug 1 2003, In : American Journal of Physiology - Renal Physiology. 285, 2 54-2, p. F191-F198

Research output: Contribution to journalArticle

238 Scopus citations

Intravital imaging of the kidney in a rat model of salt-sensitive hypertension

Endres, B. T., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S., Kamocka, M., McDermott-Roe, C., Staruschenko, A., Molitoris, B., Geurts, A. M. & Palygin, O., Aug 1 2017, In : American Journal of Physiology - Renal Physiology. 313, 2, p. F163-F173

Research output: Contribution to journalArticle

6 Scopus citations

Intravital multiphoton microscopy as a tool for studying renal physiology and pathophysiology

Sandoval, R. M. & Molitoris, B. A., Sep 1 2017, In : Methods. 128, p. 20-32 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models

Imamura, R., Isaka, Y., Sandoval, R. M., Ori, A., Adamsky, S., Feinstein, E., Molitoris, B. A. & Takahara, S., Dec 1 2010, In : Cell Transplantation. 19, 12, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

31 Scopus citations

In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury

Hall, A. M., Rhodes, G. J., Sandoval, R. M., Corridon, P. R. & Molitoris, B. A., Jan 2013, In : Kidney international. 83, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

88 Scopus citations

Ischemia activates actin depolymerizing factor: Role in proximal tubule microvillar actin alterations

Schwartz, N., Hosford, M., Sandoval, R. M., Wagner, M. C., Atkinson, S. J., Bamburg, J. & Molitoris, B. A., Apr 1 1999, In : American Journal of Physiology - Renal Physiology. 276, 4 45-4, p. F544-F551

Research output: Contribution to journalArticle

79 Scopus citations

Ischemia-induced loss of epithelial polarity. Role of the tight junction

Molitoris, B. A., Falk, S. A. & Dahl, R. H., Jan 1 1989, In : Journal of Clinical Investigation. 84, 4, p. 1334-1339 6 p.

Research output: Contribution to journalArticle

Open Access
114 Scopus citations

Ischemia induces alterations in actin filaments in renal vascular smooth muscle cells

Kwon, O., Phillips, C. L. & Molitoris, B. A., Jan 1 2002, In : American Journal of Physiology - Renal Physiology. 282, 6 51-6, p. F1012-F1019

Research output: Contribution to journalArticle

57 Scopus citations

Ischemia induces partial loss of surface membrane polarity and accumulation of putative calcium ionophores

Molitoris, B. A., Wilson, P. D., Schrier, R. W. & Simon, F. R., Jan 1 1985, In : Journal of Clinical Investigation. 76, 6, p. 2097-2105 9 p.

Research output: Contribution to journalArticle

Open Access
56 Scopus citations

Ischemia induces surface membrane dysfunction: Mechanism of altered Na+-dependent glucose transport

Molitoris, B. A. & Kinne, R., Jan 1 1987, In : Journal of Clinical Investigation. 80, 3, p. 647-654 8 p.

Research output: Contribution to journalArticle

Open Access
64 Scopus citations

Ischemic injury induces ADF relocalization to the apical domain of rat proximal tubule cells

Ashworth, S. L., Sandoval, R. M., Hosford, M., Hamburg, J. R. & Molitoris, B. A., May 1 2001, In : American Journal of Physiology - Renal Physiology. 280, 5 49-5, p. F886-F894

Research output: Contribution to journalArticle

49 Scopus citations

Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1

Wagner, M. C., Rhodes, G., Wang, E., Pruthi, V., Arif, E., Saleem, M. A., Wean, S. E., Garg, P., Verma, R., Holzman, L. B., Gattone, V., Molitoris, B. A. & Nihalani, D., Dec 19 2008, In : Journal of Biological Chemistry. 283, 51, p. 35579-35589 11 p.

Research output: Contribution to journalArticle

51 Scopus citations

Kidney Mentoring and Assessment Program for Students: A guide for engaging medical students in nephrology

Bayliss, G. P., Cobb, J., Decker, B., Hellman, R., Vasavada, N., MacKelaite, L., Shadur, C., Ilori, T., Ibrahim, T., Leight, K., Hsiao, L. L., Molitoris, B. A., Okusa, M. D. & Parker, M. G., Feb 25 2019, In : Clinical Kidney Journal. 12, 6, p. 761-766 6 p.

Research output: Contribution to journalArticle

Open Access
Open Access
4 Scopus citations

Loss of epithelial polarity: A novel hypothesis for reduced proximal tubule Na+ transport following ischemic injury

Molitoris, B. A., Chan, L. K., Shapiro, J. I., Conger, J. D. & Falk, S. A., Feb 1 1989, In : The Journal of Membrane Biology. 107, 2, p. 119-127 9 p.

Research output: Contribution to journalArticle

56 Scopus citations
11 Scopus citations

Maintenance of epithelial surface membrane lipid polarity: A role for differing phospholipid translocation rates

Molitoris, B. A. & Simon, F. R., Feb 1 1986, In : The Journal of Membrane Biology. 94, 1, p. 47-53 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Markedly increased clearance of vancomycin during hemodialysis using polysulfone dialyzers

Lanese, D. M., Alfrey, P. S. & Molitoris, B. A., Jan 1 1989, In : Kidney international. 35, 6, p. 1409-1412 4 p.

Research output: Contribution to journalArticle

Open Access
65 Scopus citations

Mechanism of Actin Polymerization in Cellular ATP Depletion

Atkinson, S. J., Hosford, M. A. & Molitoris, B. A., Feb 13 2004, In : Journal of Biological Chemistry. 279, 7, p. 5194-5199 6 p.

Research output: Contribution to journalArticle

85 Scopus citations

Mechanism of increased clearance of glycated albumin by proximal tubule cells

Wagner, M. C., Myslinski, J., Pratap, S., Flores, B., Rhodes, G., Campos-Bilderback, S. B., Sandoval, R. M., Kumar, S., Patel, M., Ashish & Molitoris, B. A., May 15 2016, In : American Journal of Physiology - Renal Physiology. 310, 10, p. F1089-F1102

Research output: Contribution to journalArticle

9 Scopus citations

Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells

Molitoris, B. A., Meyer, C., Dahl, R. & Geerdes, A., Jan 1 1993, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 264, 5 33-5, p. F907-F916

Research output: Contribution to journalArticle

32 Scopus citations

Membrane adsorption of β2-microglobulin: Equilibrium and kinetic characterization

Clark, W. R., Macias, W. L., Molitoris, B. A. & Wang, N. H. L., Oct 1994, In : Kidney international. 46, 4, p. 1140-1146 7 p.

Research output: Contribution to journalArticle

Open Access
54 Scopus citations