Bruce Molitoris

  • 15549 Citations
  • 62 h-Index
1974 …2019
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Publications 1974 2019

  • 15549 Citations
  • 62 h-Index
  • 223 Article
  • 20 Chapter
  • 2 Editorial
  • 1 Review article
Article

The distribution and disappearance of (23H) and (U14C) myoinositol in normal and diabetic dogs

Daughaday, W. H., Molitoris, B., Bier, D. M. & Yang, S., 1977, In : Diabetes. 26, sup.1

Research output: Contribution to journalArticle

Inositol
Dogs
Myosin Type I
Proximal Kidney Tubule
Myosins
Actins
Adenosine Triphosphate
73 Citations (Scopus)

The future nephrology workforce: Will there be one?

Parker, M. G., Ibrahim, T., Shaffer, R., Rosner, M. H. & Molitoris, B., Jun 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 6, p. 1501-1506 6 p.

Research output: Contribution to journalArticle

Nephrology
Mentors
Geriatrics
Medicine
Policy Making
282 Citations (Scopus)

The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: Retrieval is disrupted in nephrotic states

Russo, L. M., Sandoval, R. M., McKee, M., Osicka, T. M., Collins, A. B., Brown, D., Molitoris, B. & Comper, W. D., Mar 13 2007, In : Kidney International. 71, 6, p. 504-513 10 p.

Research output: Contribution to journalArticle

Albumins
Kidney
Albuminuria
Endocytosis
Low Density Lipoprotein Receptor-Related Protein-2
22 Citations (Scopus)

The potential role of ischemia in renal disease progression.

Molitoris, B., May 1992, In : Kidney international. Supplement. 36

Research output: Contribution to journalArticle

Sodium-Potassium-Exchanging ATPase
Membrane Lipids
Chronic Kidney Failure
Disease Progression
Membrane Proteins
124 Citations (Scopus)

The proximal tubule and albuminuria: Really!

Dickson, L. E., Wagner, M., Sandoval, R. M. & Molitoris, B., Mar 2014, In : Journal of the American Society of Nephrology. 25, 3, p. 443-453 11 p.

Research output: Contribution to journalArticle

Albuminuria
Albumins
Transcytosis
Albumin Receptors
Low Density Lipoprotein Receptor-Related Protein-2
11 Citations (Scopus)

Therapeutic drug monitoring in patients with chronic renal failure: Evaluation of the abbott TDxTM drug assay system

Sedman, A. J., Molitoris, B., Nakata, L. M. & Gal, J., 1986, In : American Journal of Nephrology. 6, 2, p. 132-134 3 p.

Research output: Contribution to journalArticle

Drug Monitoring
Chronic Kidney Failure
Digoxin
Pharmaceutical Preparations
Immunoassay
94 Citations (Scopus)

Therapeutic translation in acute kidney injury: The epithelial/endothelial axis

Molitoris, B., Jun 2 2014, In : Journal of Clinical Investigation. 124, 6, p. 2355-2363 9 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Chronic Renal Insufficiency
Cell Communication
Chronic Kidney Failure
Endothelial Cells
6 Citations (Scopus)

The role of aluminum in the pathogenesis of anemia in an outpatient hemodialysis population

Yuan, B., Klein, M. H., Contiguglia, R. S., Mishell, J. L., Seligman, P. A., Miller, N. L., Molitoris, B., Alfrey, A. C. & Shapiro, J. I., 1989, In : Renal Failure. 11, 2-3, p. 91-96 6 p.

Research output: Contribution to journalArticle

Aluminum
Renal Dialysis
Anemia
Outpatients
Population
109 Citations (Scopus)

The role of cell adhesion molecules in ischemic acute renal failure

Molitoris, B. & Marrs, J., May 1999, In : The American Journal of Medicine. 106, 5, p. 583-592 10 p.

Research output: Contribution to journalArticle

Cell Adhesion Molecules
Reperfusion Injury
Acute Kidney Injury
Integrins
Neutrophils
1 Citation (Scopus)

The role of statin therapy in patients with chronic kidney disease

Decker, B. & Molitoris, B., Jun 2006, In : Clinical Geriatrics. 14, 6, p. 29-34 6 p.

Research output: Contribution to journalArticle

Hydroxymethylglutaryl-CoA Reductase Inhibitors
Chronic Renal Insufficiency
Therapeutics
43 Citations (Scopus)

Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration

Thompson, J. D., Kornbrust, D. J., Foy, J. W. D., Solano, E. C. R., Schneider, D. J., Feinstein, E., Molitoris, B. & Erlich, S., Aug 1 2012, In : Nucleic Acid Therapeutics. 22, 4, p. 255-264 10 p.

Research output: Contribution to journalArticle

Pharmacokinetics
Intravenous Administration
Toxicology
RNA
Reperfusion Injury
90 Citations (Scopus)

Transitioning to therapy in ischemic acute renal failure

Molitoris, B., Jan 1 2003, In : Journal of the American Society of Nephrology. 14, 1, p. 265-267 3 p.

Research output: Contribution to journalArticle

Renal Circulation
Acute Kidney Injury
Ischemia
Therapeutics
36 Citations (Scopus)

Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact

Presson, R., Brown, M. B., Fisher, A. J., Sandoval, R. M., Dunn, K., Lorenz, K. S., Delp, E. J., Salama, P., Molitoris, B. & Petrache, I., Jul 2011, In : American Journal of Pathology. 179, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

Photons
Artifacts
Thorax
Microscopy
Leukocytes
24 Citations (Scopus)

Two-photon intravital fluorescence lifetime imaging of the kidney reveals cell-type specific metabolic signatures

Hato, T., Winfree, S., Day, R., Sandoval, R. M., Molitoris, B., Yoder, M., Wiggins, R. C., Zheng, Y., Dunn, K. & Dagher, P., Aug 1 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2420-2430 11 p.

Research output: Contribution to journalArticle

Optical Imaging
Photons
Microscopy
Kidney
Metabolome
48 Citations (Scopus)

Two-photon microscopy: Visualization of kidney dynamics

Ashworth, S. L., Sandoval, R. M., Tanner, G. A. & Molitoris, B., Aug 2007, In : Kidney International. 72, 4, p. 416-421 6 p.

Research output: Contribution to journalArticle

Photons
Microscopy
Kidney
Proteins
Software
104 Citations (Scopus)
Photons
Folic Acid
Microscopy
Microscopic examination
Kidney
89 Citations (Scopus)

Urinary actin, interleukin-6, and interleukin-8 may predict sustained ARF after ischemic injury in renal allografts

Kwon, O., Molitoris, B., Pescovitz, M. & Kelly, K., May 1 2003, In : American Journal of Kidney Diseases. 41, 5, p. 1074-1087 14 p.

Research output: Contribution to journalArticle

Interleukin-8
Acute Kidney Injury
Allografts
Actins
Interleukin-6
10 Citations (Scopus)

Urinary biomarkers: Alone are they enough?

Molitoris, B., Jul 1 2015, In : Journal of the American Society of Nephrology. 26, 7, p. 1485-1488 4 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-2
Insulin-Like Growth Factor Binding Proteins
Acute Kidney Injury
Renal Dialysis
Biomarkers
82 Citations (Scopus)

Uropathogenic escherichia coli P and type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction

Melican, K., Sandoval, R. M., Kader, A., Josefsson, L., Tanner, G. A., Molitoris, B. & Richter-Dahlfors, A., Feb 2011, In : PLoS Pathogens. 7, 2, e1001298.

Research output: Contribution to journalArticle

Uropathogenic Escherichia coli
Nephrons
Bacterial Infections
Epithelium
Bowman Capsule
2 Citations (Scopus)
Albuminuria
Photons
Microscopy
Aptitude
Fluorescent Dyes
27 Citations (Scopus)

Utilization of nitrogen from selected purines and pyrimidines and from urea by the young chick

Baker, D. H. & Molitoris, B., 1974, In : Journal of Nutrition. 104, 5, p. 553-557 5 p.

Research output: Contribution to journalArticle

Pyrimidines
Purines
pyrimidines
purines
Urea
6 Citations (Scopus)

Yet another advance in understanding albuminuria?

Molitoris, B., Dec 2010, In : Journal of the American Society of Nephrology. 21, 12, p. 2013-2015 3 p.

Research output: Contribution to journalArticle

Animal Disease Models
Podocytes
Albuminuria
Kidney Diseases
Glomerular Filtration Rate
Chapter
2 Citations (Scopus)

Acute Kidney Injury

Molitoris, B., Jul 2011, Goldman's Cecil Medicine: Twenty Fourth Edition. Elsevier Inc., Vol. 1. p. 756-761 6 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Citation (Scopus)

Aminoglycoside-Induced Nephrotoxicity

Decker, B. & Molitoris, B., Dec 15 2017, Renal Toxicology. Elsevier Inc., Vol. 14-15. p. 256-273 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aminoglycosides
Endocytosis
Kidney
Incidence
Low Density Lipoprotein Receptor-Related Protein-2

Aminoglycoside-Induced Nephrotoxicity

Decker, B. & Molitoris, B., Aug 12 2010, Renal Toxicology. Elsevier Inc., Vol. 7. p. 329-346 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Aminoglycosides
Endocytosis
Kidney
Incidence
Low Density Lipoprotein Receptor-Related Protein-2

Application of physiological shear stress to renal tubular epithelial cells

Ferrell, N., Sandoval, R. M., Molitoris, B., Brakeman, P., Roy, S. & Fissell, W. H., Jan 1 2019, Methods in Cell Biology. Academic Press Inc., (Methods in Cell Biology).

Research output: Chapter in Book/Report/Conference proceedingChapter

Epithelial Cells
Kidney
Lab-On-A-Chip Devices
Kidney Tubules
Nephrons
18 Citations (Scopus)

Effects of vitamin D-induced chronic hypercalcemia on rat renal cortical plasma membranes and mitochondria

Levi, M., Molitoris, B., Burke, T. J., Schrier, R. W. & Simon, F. R., 1987, American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 2 ed. Vol. 252.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hypercalcemia
Vitamin D
Mitochondria
Cell Membrane
Kidney
1 Citation (Scopus)

Establishment of Polarity in Epithelial Cells of the Developing Nephron

Karp, S. & Molitoris, B., Mar 15 2003, The Kidney: From Normal Development to Congenital Disease. Elsevier Inc., p. 211-220 10 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Nephrons
Epithelial Cells
Membranes
Scaffolds
Actins

Fluorescent dextrans in intravital multi- photon microscopy

Sandoval, R. M. & Molitoris, B., Jan 1 2014, Advances in Intravital Microscopy: From Basic to Clinical Research. Springer Netherlands, p. 205-219 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Dextrans
Photons
Microscopy
Kidney
Polymers

Fluorescent Imaging and Microscopy for Dynamic Processes in Rats

Sandoval, R. M., Molitoris, B. & Palygin, O., Jan 1 2019, Methods in Molecular Biology. Humana Press Inc., p. 151-175 25 p. (Methods in Molecular Biology; vol. 2018).

Research output: Chapter in Book/Report/Conference proceedingChapter

Microscopy
Photons
Kidney
Genetically Modified Animals
Translational Medical Research
1 Citation (Scopus)

Ischemia-induced tight junction dysfunction in the kidney

Marrs, J. A. & Molitoris, B., Jan 1 2001, Tight Junctions. CRC Press, p. 533-552 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Tight Junctions
Ischemia
Epithelial Cells
Waste Products
Kidney
10 Citations (Scopus)

Kidney endothelial dysfunction: Ischemia, localized infections and sepsis

Molitoris, B. & Sandoval, R. M., Sep 2011, Contributions to Nephrology. Vol. 174. p. 108-118 11 p. (Contributions to Nephrology; vol. 174).

Research output: Chapter in Book/Report/Conference proceedingChapter

Sepsis
Leukocytes
Ischemia
Kidney
Endothelial Cells
11 Citations (Scopus)

Multiphoton imaging techniques in acute kidney injury

Molitoris, B. & Sandoval, R. M., Apr 2010, Contributions to Nephrology. Vol. 165. p. 46-53 8 p. (Contributions to Nephrology; vol. 165).

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Kidney Injury
Microscopy
Research Personnel
Kidney
Wounds and Injuries
1 Citation (Scopus)

Pathophysiology of Acute Kidney Injury

Molitoris, B. & Sharfuddin, A., 2013, Seldin and Geibisch's The Kidney. Elsevier Inc., Vol. 2. p. 2527-2575 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Kidney Injury
1 Citation (Scopus)

Pathophysiology of Acute Kidney Injury

Sharfuddin, A. & Molitoris, B., 2008, Seldin and Giebisch's The Kidney. Elsevier Inc., p. 2143-2191 49 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Practical Considerations of Renal Biopsies in Critical Care Patients

Modi, J. R., Liapis, H., Molitoris, B. A. & Eadon, M. T., Dec 6 2017, Critical Care Nephrology: Third Edition. Elsevier Inc., p. 167-173.e1

Research output: Chapter in Book/Report/Conference proceedingChapter

Critical Care
Kidney
Biopsy
Disease Management
Acute Kidney Injury
4 Citations (Scopus)

Quantifying dynamic kidney processes utilizing multi-photon microscopy

Molitoris, B. & Sandoval, R. M., 2007, Contributions to Nephrology. Vol. 156. p. 227-235 9 p. (Contributions to Nephrology; vol. 156).

Research output: Chapter in Book/Report/Conference proceedingChapter

Photons
Microscopy
Research Personnel
Kidney
Technology
20 Citations (Scopus)

Quantifying endocytosis in vivo using intravital two-photon microscopy

Sandoval, R. M. & Molitoris, B., 2008, Methods in Molecular Biology. Humana Press, Vol. 440. p. 389-402 14 p. (Methods in Molecular Biology; vol. 440).

Research output: Chapter in Book/Report/Conference proceedingChapter

Endocytosis
Photons
Microscopy
Research Personnel
Proximal Kidney Tubule
60 Citations (Scopus)

Renal apical membrane cholesterol and fluidity in regulation of phosphate transport

Molitoris, B., Alfrey, A. C., Harris, R. A. & Simon, F. R., 1985, American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 1 ed. Vol. 18.

Research output: Chapter in Book/Report/Conference proceedingChapter

Membrane Fluidity
Phosphates
Cholesterol
Kidney
Membranes
2 Citations (Scopus)

Renal endothelium

Molitoris, B., Jan 1 2007, Endothelial Biomedicine. Cambridge University Press, p. 1271-1277 7 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Endothelial cells
Endothelium
Kidney
Endothelial Cells
Color films

The Physiology of the Glomerulus

Dean, D. F. & Molitoris, B., Dec 6 2017, Critical Care Nephrology: Third Edition. Elsevier Inc., p. 35-42.e2

Research output: Chapter in Book/Report/Conference proceedingChapter

Arterioles
Glomerular Filtration Barrier
Low Density Lipoprotein Receptor-Related Protein-2
Epithelial Cells
Sodium Potassium Chloride Symporter Inhibitors

Tubular mechanisms in proteinuria

Verma, S. K. & Molitoris, B., Jan 1 2016, Proteinuria: Basic Mechanisms, Pathophysiology and Clinical Relevance. Springer International Publishing, p. 23-40 18 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Low Density Lipoprotein Receptor-Related Protein-2
Factor IX
Proteinuria
Electron microscopy
affinity
Editorial

Beyond Biomarkers: Machine Learning in Diagnosing Acute Kidney Injury

Molitoris, B., May 1 2019, In : Mayo Clinic Proceedings. 94, 5, p. 748-750 3 p.

Research output: Contribution to journalEditorial

Acute Kidney Injury
Biomarkers
Machine Learning
1 Citation (Scopus)

Removal of Vancomycin by Hemodialysis: A Significant and Overlooked Consideration

Lanese, D. M. & Molitoris, B., 1989, In : Seminars in Dialysis. 2, 2, p. 73-74 2 p.

Research output: Contribution to journalEditorial

Vancomycin
Renal Dialysis
Review article
1 Citation (Scopus)

DNA damage response protects against progressive kidney disease

Molitoris, B. A., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4574-4575 2 p.

Research output: Contribution to journalReview article

Kidney Diseases
DNA Damage
Wounds and Injuries
G2 Phase Cell Cycle Checkpoints
Acute Kidney Injury