Bruce Molitoris

  • 15900 Citations
  • 62 h-Index
1974 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

Filter
Article
2020

Immunotoxin SS1P is rapidly removed by proximal tubule cells of kidney, whose damage contributes to albumin loss in urine

Liu, X. F., Wei, J., Zhou, Q., Molitoris, B. A., Sandoval, R., Kobayashi, H., Okada, R., Nagaya, T., Karim, B., Butcher, D. & Pastan, I., Mar 17 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 11, p. 6086-6091 6 p.

Research output: Contribution to journalArticle

2019

A novel fluorescent clinical method to rapidly quantify plasma volume

Molitoris, B. A., George, A. G., Murray, P. T., Meier, D., Reilly, E. S., Barreto, E., Sandoval, R. M., Rizk, D. V., Shaw, A. D. & Peacock, W. F., Mar 1 2019, In : CardioRenal Medicine. 9, 3, p. 168-179 12 p.

Research output: Contribution to journalArticle

Open Access

Kidney Mentoring and Assessment Program for Students: A guide for engaging medical students in nephrology

Bayliss, G. P., Cobb, J., Decker, B., Hellman, R., Vasavada, N., MacKelaite, L., Shadur, C., Ilori, T., Ibrahim, T., Leight, K., Hsiao, L. L., Molitoris, B. A., Okusa, M. D. & Parker, M. G., Feb 25 2019, In : Clinical Kidney Journal. 12, 6, p. 761-766 6 p.

Research output: Contribution to journalArticle

Open Access

The archaeal Dps nanocage targets kidney proximal tubules via glomerular filtration

Uchida, M., Maier, B., Waghwani, H. K., Selivanovitch, E., Louise Pay, S., Avera, J., Jun Yun, E., Sandoval, R. M., Molitoris, B. A., Zollman, A., Douglas, T. & Hato, T., Sep 3 2019, In : Journal of Clinical Investigation. 129, 9, p. 3941-3951 11 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2018

A novel method for rapid bedside measurement of GFR

Rizk, D. V., Meier, D., Sandoval, R. M., Chacana, T., Reilly, E. S., Seegmiller, J. C., DeNoia, E., Strickland, J. S., Muldoon, J. & Molitoris, B. A., Jun 2018, In : Journal of the American Society of Nephrology. 29, 6, p. 1609-1613 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
25 Scopus citations

Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection

Kolb, A. L., Corridon, P. R., Zhang, S., Xu, W., Witzmann, F., Collett, J. A., Rhodes, G. J., Winfree, S., Bready, D., Pfeffenberger, Z. J., Pomerantz, J. M., Hato, T., Nagami, G. T., Molitoris, B., Basile, D., Atkinson, S. J. & Bacallao, R., Apr 1 2018, In : Journal of the American Society of Nephrology. 29, 4, p. 1154-1164 11 p.

Research output: Contribution to journalArticle

1 Scopus citations

Protective vascular coagulation in response to bacterial infection of the kidney is regulated by bacterial lipid A and host CD147

Schulz, A., Chuquimia, O. D., Antypas, H., Steiner, S. E., Sandoval, R. M., Tanner, G. A., Molitoris, B. A., Richter-Dahlfors, A. & Melican, K., Nov 1 2018, In : Pathogens and Disease. 76, 8, fty087.

Research output: Contribution to journalArticle

3 Scopus citations
2017

Hydrodynamic isotonic fluid delivery ameliorates moderate-to-severe ischemia-reperfusion injury in rat kidneys

Collett, J. A., Corridon, P. R., Mehrotra, P., Kolb, A. L., Rhodes, G. J., Miller, C. A., Molitoris, B. A., Pennington, J. G., Sandoval, R. M., Atkinson, S. J., Campos-Bilderback, S. B., Basile, D. P. & Bacallao, R. L., Jul 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2081-2092 12 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibition of avb5 integrin attenuates vascular permeability and protects against renal ischemia-reperfusion injury

McCurley, A., Alimperti, S., Campos-Bilderback, S. B., Sandoval, R. M., Calvino, J. E., Reynolds, T. L., Quigley, C., Mugford, J. W., Polacheck, W. J., Gomez, I. G., Dovey, J., Marsh, G., Huang, A., Qian, F., Weinreb, P. H., Dolinski, B. M., Moore, S., Duffield, J. S., Chen, C. S., Molitoris, B. A. & 2 others, Violette, S. M. & Crackower, M. A., Jun 2017, In : Journal of the American Society of Nephrology. 28, 6, p. 1741-1752 12 p.

Research output: Contribution to journalArticle

11 Scopus citations

Intravital imaging of the kidney in a rat model of salt-sensitive hypertension

Endres, B. T., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S., Kamocka, M., McDermott-Roe, C., Staruschenko, A., Molitoris, B., Geurts, A. M. & Palygin, O., Aug 1 2017, In : American Journal of Physiology - Renal Physiology. 313, 2, p. F163-F173

Research output: Contribution to journalArticle

6 Scopus citations

Intravital multiphoton microscopy as a tool for studying renal physiology and pathophysiology

Sandoval, R. M. & Molitoris, B. A., Sep 1 2017, In : Methods. 128, p. 20-32 13 p.

Research output: Contribution to journalArticle

4 Scopus citations

Two-photon intravital fluorescence lifetime imaging of the kidney reveals cell-type specific metabolic signatures

Hato, T., Winfree, S., Day, R., Sandoval, R. M., Molitoris, B. A., Yoder, M. C., Wiggins, R. C., Zheng, Y., Dunn, K. W. & Dagher, P. C., Aug 2017, In : Journal of the American Society of Nephrology. 28, 8, p. 2420-2430 11 p.

Research output: Contribution to journalArticle

27 Scopus citations
2016

ABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial

Mccullough, P. A., Bennett-Guerrero, E., Chawla, L. S., Beaver, T., Mehta, R. L., Molitoris, B. A., Eldred, A., Ball, G., Lee, H. J., Houser, M. T. & Khan, S., Aug 2016, In : Journal of the American Heart Association. 5, 8, e003549.

Research output: Contribution to journalArticle

14 Scopus citations

Mechanism of increased clearance of glycated albumin by proximal tubule cells

Wagner, M. C., Myslinski, J., Pratap, S., Flores, B., Rhodes, G., Campos-Bilderback, S. B., Sandoval, R. M., Kumar, S., Patel, M., Ashish & Molitoris, B. A., May 15 2016, In : American Journal of Physiology - Renal Physiology. 310, 10, p. F1089-F1102

Research output: Contribution to journalArticle

9 Scopus citations

Proximal tubules have the capacity to regulate uptake of albumin

Wagner, M. C., Campos-Bilderback, S. B., Chowdhury, M., Flores, B., Lai, X., Myslinski, J., Pandit, S., Sandoval, R. M., Wean, S. E., Wei, Y., Satlin, L. M., Wiggins, R. C., Witzmann, F. A. & Molitoris, B. A., Feb 2016, In : Journal of the American Society of Nephrology. 27, 2, p. 482-494 13 p.

Research output: Contribution to journalArticle

38 Scopus citations

Quantifying Glomerular Filtration Rates in Acute Kidney Injury: A Requirement for Translational Success

Molitoris, B. & Reilly, E. S., 2016, (Accepted/In press) In : Seminars in Nephrology.

Research output: Contribution to journalArticle

22 Scopus citations

Renal Hemodynamics in AKI: In Search of New Treatment Targets

The ADQI XIII Work Group, Jan 2016, In : Journal of the American Society of Nephrology. 27, 1, p. 49-58 10 p.

Research output: Contribution to journalArticle

43 Scopus citations
7 Scopus citations
2015

Cross-disciplinary biomarkers research: Lessons learned by the CKD biomarkers consortium

CKD Biomarkers Consortium, Jan 1 2015, In : Clinical Journal of the American Society of Nephrology. 10, 5, p. 894-902 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Nephrology research - The past, present and future

Floege, J., Mak, R. H., Molitoris, B., Remuzzi, G. & Ronco, P., Nov 1 2015, In : Nature Reviews Nephrology. 11, 11, p. 677-687 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

Renal effects of atorvastatin and rosuvastatin in patients with diabetes who have progressive renal disease (PLANET I): A randomised clinical trial

de Zeeuw, D., Anzalone, D. A., Cain, V. A., Cressman, M. D., Heerspink, H. J. L., Molitoris, B. A., Monyak, J. T., Parving, H. H., Remuzzi, G., Sowers, J. R. & Vidt, D. G., Mar 1 2015, In : The Lancet Diabetes and Endocrinology. 3, 3, p. 181-190 10 p.

Research output: Contribution to journalArticle

68 Scopus citations

Shear stress is normalized in glomerular capillaries following 5⁄6 nephrectomy

Ferrell, N., Sandoval, R. M., Bian, A., Campos-Bilderback, S. B., Molitoris, B. A. & Fissell, W. H., Mar 15 2015, In : American Journal of Physiology - Renal Physiology. 308, 6, p. F588-F593

Research output: Contribution to journalArticle

13 Scopus citations
2014

Effects of biomechanical forces on signaling in the cortical collecting duct (CCD)

Carrisoza-Gaytan, R., Liu, Y., Flores, D., Else, C., Lee, H. G., Rhodes, G., Sandoval, R. M., Kleyman, T. R., Lee, F. Y. I., Molitoris, B., Satlin, L. M. & Rohatgi, R., Jul 15 2014, In : American Journal of Physiology - Renal Physiology. 307, 2, p. F195-F204

Research output: Contribution to journalArticle

19 Scopus citations

Screening: Screening for kidney disease- A lost opportunity

Molitoris, B. A., Jan 1 2014, In : Nature Reviews Nephrology. 10, 1, p. 6-8 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
2013

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

31 Scopus citations

In vivo multiphoton imaging of mitochondrial structure and function during acute kidney injury

Hall, A. M., Rhodes, G. J., Sandoval, R. M., Corridon, P. R. & Molitoris, B. A., Jan 2013, In : Kidney international. 83, 1, p. 72-83 12 p.

Research output: Contribution to journalArticle

88 Scopus citations
18 Scopus citations
2012

A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney

Imamura, R., Isaka, Y., Sandoval, R. M., Ichimaru, N., Abe, T., Okumi, M., Yazawa, K., Kitamura, H., Kaimori, J., Nonomura, N., Rakugi, H., Molitoris, B. A. & Takahara, S., Dec 1 2012, In : Clinical and Experimental Nephrology. 16, 6, p. 852-862 11 p.

Research output: Contribution to journalArticle

14 Scopus citations

A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals

Wang, E., Meier, D. J., Sandoval, R. M., Von Hendy-Willson, V. E., Pressler, B. M., Bunch, R. M., Alloosh, M., Sturek, M. S., Schwartz, G. J. & Molitoris, B. A., Jan 1 2012, In : Kidney international. 81, 1, p. 112-117 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat

Saleh, M. A., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S. B., Molitoris, B. A. & Pollock, D. M., Oct 15 2012, In : Life Sciences. 91, 13-14, p. 634-637 4 p.

Research output: Contribution to journalArticle

13 Scopus citations

Designing clinical trials in acute kidney injury

Molitoris, B. A., Okusa, M. D., Palevsky, P. M., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 842-843 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Design of clinical trials in acute kidney injury: A report from an NIDDK workshop-prevention trials

Okusa, M. D., Molitoris, B. A., Palevsky, P. M., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Faubel, S., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T. H., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 851-855 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Design of clinical trials in acute kidney injury: Report from an NIDDK workshop on trial methodology

Palevsky, P. M., Molitoris, B. A., Okusa, M. D., Levin, A., Waikar, S. S., Wald, R., Chertow, G. M., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Faubel, S. G., Kellum, J. A., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 844-850 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Design of clinical trials in AKI: A report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings

Molitoris, B. A., Okusa, M. D., Palevsky, P. M., Chawla, L. S., Kaufman, J. S., Devarajan, P., Toto, R. M., Hsu, C. Y., Greene, T. H., Faubel, S. G., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chinchilli, V. M. & 15 others, Liu, K. D., Cheung, A. K., Weisbord, S. D., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 856-860 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

Multiphoton microscopy applied for real-time intravital imaging of bacterial infections in vivo

Choong, F. X., Sandoval, R. M., Molitoris, B. & Richter-Dahlfors, A., 2012, In : Methods in Enzymology. 506, p. 35-61 27 p.

Research output: Contribution to journalArticle

12 Scopus citations

Multiple factors influence glomerular albumin permeability in rats

Sandoval, R. M., Wagner, M. C., Patel, M., Campos-Bilderback, S. B., Rhodes, G. J., Wang, E., Wean, S. E., Clendenon, S. S. & Molitoris, B. A., Mar 1 2012, In : Journal of the American Society of Nephrology. 23, 3, p. 447-457 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

Toxicological and pharmacokinetic properties of chemically modified siRNAs targeting p53 RNA following intravenous administration

Thompson, J. D., Kornbrust, D. J., Foy, J. W. D., Solano, E. C. R., Schneider, D. J., Feinstein, E., Molitoris, B. A. & Erlich, S., Aug 1 2012, In : Nucleic Acid Therapeutics. 22, 4, p. 255-264 10 p.

Research output: Contribution to journalArticle

44 Scopus citations
2011

Acute kidney injury in older adults

Anderson, S., Eldadah, B., Halter, J. B., Hazzard, W. R., Himmelfarb, J., Horne, F. M. F., Kimmel, P. L., Molitoris, B. A., Murthy, M., O'Hare, A. M., Schmader, K. E. & High, K. P., Jan 1 2011, In : Journal of the American Society of Nephrology. 22, 1, p. 28-38 11 p.

Research output: Contribution to journalArticle

101 Scopus citations

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury

Basile, D. P., Friedrich, J. L., Spahic, J., Knipe, N., Mang, H., Leonard, E. C., Changizi-Ashtiyani, S., Bacallao, R. L., Molitoris, B. A. & Sutton, T. A., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3, p. F721-F733

Research output: Contribution to journalArticle

180 Scopus citations

The antibiotic gentamicin inhibits specific protein trafficking functions of the arf1/2 family of GTPases

Lin, L., Wagner, M. C., Cocklin, R., Kuzma, A., Harrington, M., Molitoris, B. A. & Goebl, M. G., Jan 1 2011, In : Antimicrobial Agents and Chemotherapy. 55, 1, p. 246-254 9 p.

Research output: Contribution to journalArticle

4 Scopus citations

The future nephrology workforce: Will there be one?

Parker, M. G., Ibrahim, T., Shaffer, R., Rosner, M. H. & Molitoris, B. A., Jun 1 2011, In : Clinical Journal of the American Society of Nephrology. 6, 6, p. 1501-1506 6 p.

Research output: Contribution to journalArticle

74 Scopus citations

Two-photon imaging within the murine thorax without respiratory and cardiac motion artifact

Presson, R. G., Brown, M. B., Fisher, A. J., Sandoval, R. M., Dunn, K. W., Lorenz, K. S., Delp, E. J., Salama, P., Molitoris, B. A. & Petrache, I., Jul 1 2011, In : American Journal of Pathology. 179, 1, p. 75-82 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Uropathogenic escherichia coli P and type 1 fimbriae act in synergy in a living host to facilitate renal colonization leading to nephron obstruction

Melican, K., Sandoval, R. M., Kader, A., Josefsson, L., Tanner, G. A., Molitoris, B. A. & Richter-Dahlfors, A., Feb 1 2011, In : PLoS pathogens. 7, 2, e1001298.

Research output: Contribution to journalArticle

87 Scopus citations
2010

Intravital two-photon microscopy assessment of renal protection efficacy of siRNA for p53 in experimental rat kidney transplantation models

Imamura, R., Isaka, Y., Sandoval, R. M., Ori, A., Adamsky, S., Feinstein, E., Molitoris, B. A. & Takahara, S., Dec 1 2010, In : Cell Transplantation. 19, 12, p. 1659-1670 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
32 Scopus citations
2009

Acute kidney injury increases risk of ESRD among elderly

Ishani, A., Xue, J. L., Himmelfarb, J., Eggers, P. W., Kimmel, P. L., Molitoris, B. A. & Collins, A. J., Jan 1 2009, In : Journal of the American Society of Nephrology. 20, 1, p. 223-228 6 p.

Research output: Contribution to journalArticle

718 Scopus citations

Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation

Campos, S. B., Ashworth, S. L., Wean, S., Hosford, M., Sandoval, R. M., Hallett, M. A., Atkinson, S. J. & Molitoris, B. A., Mar 1 2009, In : American Journal of Physiology - Renal Physiology. 296, 3, p. F487-F495

Research output: Contribution to journalArticle

37 Scopus citations

Early monitoring of acute tubular necrosis in the rat kidney by 23Na-MRI

Atthe, B. K., Babsky, A. M., Hopewell, P. N., Phillips, C. L., Molitoris, B. A. & Bansal, N., Nov 1 2009, In : American Journal of Physiology - Renal Physiology. 297, 5, p. F1288-F1298

Research output: Contribution to journalArticle

21 Scopus citations

Impaired tubular uptake explains albuminuria in early diabetic nephropathy

Russo, L. M., Sandoval, R. M., Campos, S. B., Molitoris, B. A., Comper, W. D. & Brown, D., Mar 1 2009, In : Journal of the American Society of Nephrology. 20, 3, p. 489-494 6 p.

Research output: Contribution to journalArticle

163 Scopus citations