Bruce Molitoris

  • 16112 Citations
  • 62 h-Index
1974 …2020

Research output per year

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Publications

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9 Scopus citations

ABT-719 for the Prevention of Acute Kidney Injury in Patients Undergoing High-Risk Cardiac Surgery: A Randomized Phase 2b Clinical Trial

Mccullough, P. A., Bennett-Guerrero, E., Chawla, L. S., Beaver, T., Mehta, R. L., Molitoris, B. A., Eldred, A., Ball, G., Lee, H. J., Houser, M. T. & Khan, S., Aug 2016, In : Journal of the American Heart Association. 5, 8, e003549.

Research output: Contribution to journalArticle

14 Scopus citations

Actin cytoskeleton in ischemic acute renal failure

Molitoris, B. A., Harrington, J. T., Perrone, R., Jaber, B., Herman, I. M., Balakrishnan, V. S., Pahari, D. K. & Levey, A. S., Aug 2004, In : Kidney international. 66, 2, p. 871-883 13 p.

Research output: Contribution to journalArticle

53 Scopus citations

Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2

Gupta, A., Rhodes, G. J., Berg, D. T., Gerlitz, B., Molitoris, B. A. & Grinnell, B. W., Jul 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 1, p. F245-F254

Research output: Contribution to journalArticle

109 Scopus citations

Acute kidney injury increases risk of ESRD among elderly

Ishani, A., Xue, J. L., Himmelfarb, J., Eggers, P. W., Kimmel, P. L., Molitoris, B. A. & Collins, A. J., Jan 1 2009, In : Journal of the American Society of Nephrology. 20, 1, p. 223-228 6 p.

Research output: Contribution to journalArticle

730 Scopus citations

Acute kidney injury in older adults

Anderson, S., Eldadah, B., Halter, J. B., Hazzard, W. R., Himmelfarb, J., Horne, F. M. F., Kimmel, P. L., Molitoris, B. A., Murthy, M., O'Hare, A. M., Schmader, K. E. & High, K. P., Jan 2011, In : Journal of the American Society of Nephrology. 22, 1, p. 28-38 11 p.

Research output: Contribution to journalArticle

104 Scopus citations

Acute kidney injury network: Report of an initiative to improve outcomes in acute kidney injury

Mehta, R. L., Kellum, J. A., Shah, S. V., Molitoris, B. A., Ronco, C., Warnock, D. G., Levin, A., Bagga, A., Bakkaloglu, A., Bonventre, J. V., Burdmann, E. A., Chen, Y., Devarajan, P., D'Intini, V., Dobb, G., Durbin, C. G., Eckardt, K. U., Guerin, C., Herget-Rosenthal, S., Hoste, E. & 19 others, Joannidis, M., Kellum, J. A., Kirpalani, A., Lassnigg, A., Le Gall, J. R., Levin, A., Lombardi, R., Macias, W., Manthous, C., Mehta, R. L., Molitoris, B. A., Ronco, C., Schetz, M., Schortgen, F., Shah, S. V., Tan, P. S. K., Wang, H., Warnock, D. G. & Webb, S., Mar 1 2007, In : Critical Care. 11, R31.

Research output: Contribution to journalArticle

4250 Scopus citations

Acute parathyroid hormone stimulation of myo inositol release by isolated perfused dog kidneys

Molitoris, B. A., Hruska, K. & Daughaday, W. H., Jan 1 1976, In : Clinical research. 24, 4, p. 530A

Research output: Contribution to journalArticle

Acute renal failure in the 21st century: Recommendations for management and outcomes assessment

DuBose, T. D., Warnock, D. G., Mehta, R. L., Bonventre, J. V., Hammerman, M. R., Molitoris, B. A., Paller, M. S., Siegel, N. J., Scherbenske, J. & Striker, G. E., May 1997, In : American Journal of Kidney Diseases. 29, 5, p. 793-799 7 p.

Research output: Contribution to journalArticle

89 Scopus citations

Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: Enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model

Raikwar, S. P., Temm, C. J., Raikwar, N. S., Kao, C., Molitoris, B. A. & Gardner, T. A., Dec 2005, In : Molecular Therapy. 12, 6, p. 1091-1100 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion

Ashworth, S. L., Southgate, E. L., Sandoval, R. M., Meberg, P. J., Bamburg, J. R. & Molitoris, B. A., Apr 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 4 53-4, p. F852-F862

Research output: Contribution to journalArticle

45 Scopus citations

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

31 Scopus citations

Aminoglycoside antibiotics traffic to the Golgi complex in LLC-PK1 cells

Sandoval, R., Leiser, J. & Molitoris, B. A., Feb 1 1998, In : Journal of the American Society of Nephrology. 9, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

69 Scopus citations

A nonerythropoietic derivative of erythropoietin inhibits tubulointerstitial fibrosis in remnant kidney

Imamura, R., Isaka, Y., Sandoval, R. M., Ichimaru, N., Abe, T., Okumi, M., Yazawa, K., Kitamura, H., Kaimori, J., Nonomura, N., Rakugi, H., Molitoris, B. A. & Takahara, S., Dec 1 2012, In : Clinical and Experimental Nephrology. 16, 6, p. 852-862 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

A non-nephrotoxic gentamicin congener that retains antimicrobial efficacy

Sandoval, R. M., Reilly, J. P., Running, W., Campos, S. B., Santos, J. R., Phillips, C. L. & Molitoris, B. A., Oct 1 2006, In : Journal of the American Society of Nephrology. 17, 10, p. 2697-2705 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

A novel fluorescent clinical method to rapidly quantify plasma volume

Molitoris, B. A., George, A. G., Murray, P. T., Meier, D., Reilly, E. S., Barreto, E., Sandoval, R. M., Rizk, D. V., Shaw, A. D. & Peacock, W. F., Mar 1 2019, In : CardioRenal Medicine. 9, 3, p. 168-179 12 p.

Research output: Contribution to journalArticle

Open Access

A novel method for rapid bedside measurement of GFR

Rizk, D. V., Meier, D., Sandoval, R. M., Chacana, T., Reilly, E. S., Seegmiller, J. C., DeNoia, E., Strickland, J. S., Muldoon, J. & Molitoris, B. A., Jun 2018, In : Journal of the American Society of Nephrology. 29, 6, p. 1609-1613 5 p.

Research output: Contribution to journalArticle

11 Scopus citations
153 Scopus citations

Apically and basolaterally internalized aminoglycosides colocalize in LLC- PK1 lysosomes and alter cell function

Ford, D. M., Dahl, R. H., Lamp, C. A. & Molitoris, B. A., 1994, In : American Journal of Physiology - Cell Physiology. 266, 1 35-1, p. C52-C57

Research output: Contribution to journalArticle

23 Scopus citations

A portable fiberoptic ratiometric fluorescence analyzer provides rapid point-of-care determination of glomerular filtration rate in large animals

Wang, E., Meier, D. J., Sandoval, R. M., Von Hendy-Willson, V. E., Pressler, B. M., Bunch, R. M., Alloosh, M., Sturek, M. S., Schwartz, G. J. & Molitoris, B. A., Jan 1 2012, In : Kidney international. 81, 1, p. 112-117 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Assessment of the quantity of biologically available choline in soybean meal.

Molitoris, B. A. & Baker, D. H., Feb 1976, In : Journal of animal science. 42, 2, p. 481-489 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

A statistical method for determining the breakpoint of two lines

Jones, R. H. & Molitoris, B. A., Aug 15 1984, In : Analytical biochemistry. 141, 1, p. 287-290 4 p.

Research output: Contribution to journalArticle

151 Scopus citations

ATP depletion alters myosin Iβ cellular location in LLC-PK1 cells

Wagner, M. C. & Molitoris, B. A., Jan 1 1997, In : American Journal of Physiology - Cell Physiology. 272, 5 41-5, p. C1680-C1690

Research output: Contribution to journalArticle

29 Scopus citations

Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis

Melican, K., Boekel, J., Månsson, L. E., Sandoval, R. M., Tanner, G. A., Källskog, Ö., Palm, F., Molitoris, B. A. & Richter-Dahlfors, A., Sep 16 2008, In : Cellular Microbiology. 10, 10, p. 1987-1998 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Beta-2-Microglobulin-Associated amyloidosis in chronic hemodialysis patients with carpal tunnel syndrome

Ullian, M. E., Hammond, W. S., Alfrey, A. C., Schultz, A. & Molitoris, B. A., Mar 1989, In : Medicine (United States). 68, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

Bilateral congenital renal arteriovenous fistulas

Ullian, M. E. & Molitoris, B. A., Jan 1 1987, In : Clinical Nephrology. 27, 6, p. 293-297 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

Cardiovascular disease in patients with chronic kidney disease

Jaradat, M. I. & Molitoris, B. A., Nov 2002, In : Seminars in nephrology. 22, 6, p. 459-473 15 p.

Research output: Contribution to journalArticle

24 Scopus citations

Cellular ATP depletion induces disruption of the spectrin cytoskeletal network

Molitoris, B. A., Dahl, R. & Hosford, M., 1996, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 271, 4 40-4, p. F790-F798

Research output: Contribution to journalArticle

55 Scopus citations

Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment

Sundin, D. P., Meyer, C., Dahl, R., Geerdes, A., Sandoval, R. & Molitoris, B. A., May 21 1997, In : American Journal of Physiology - Cell Physiology. 272, 4 41-4, p. C1309-C1318

Research output: Contribution to journalArticle

20 Scopus citations

Characteristics of EYFP-actin and visualization of actin dynamics during ATP depletion and repletion

Herget-Rosenthal, S., Hosford, M., Kribben, A., Atkinson, S. J., Sandoval, R. M. & Molitoris, B. A., Dec 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1858-C1870

Research output: Contribution to journalArticle

19 Scopus citations

Characterization of ischemia-induced loss of epithelial polarity

Molitoris, B. A., Hoilien, C. A., Dahl, R., Ahnen, D. J., Wilson, P. D. & Kim, J., Dec 1 1988, In : The Journal of Membrane Biology. 106, 3, p. 233-242 10 p.

Research output: Contribution to journalArticle

62 Scopus citations

Characterization of the beta2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B., 1994, In : The American journal of physiology. 267, 3 part 2

Research output: Contribution to journalArticle

Characterization of the β2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B. A., Jan 1 1994, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 267, 3 36-3, p. F380-F389

Research output: Contribution to journalArticle

22 Scopus citations

Choline utilization in the chick as influenced by levels of dietary protein and methionine

Molitoris, B. A. & Baker, D. H., Jan 1 1976, In : Journal of Nutrition. 106, 3, p. 412-418 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Chronic endothelin-1 infusion elevates glomerular sieving coefficient and proximal tubular albumin reuptake in the rat

Saleh, M. A., Sandoval, R. M., Rhodes, G. J., Campos-Bilderback, S. B., Molitoris, B. A. & Pollock, D. M., Oct 15 2012, In : Life Sciences. 91, 13-14, p. 634-637 4 p.

Research output: Contribution to journalArticle

15 Scopus citations

Cofilin mediates ATP depletion-induced endothelial cell actin alterations

Suurna, M. V., Ashworth, S. L., Hosford, M., Sandoval, R. M., Wean, S. E., Shah, B. M., Bamburg, J. R. & Molitoris, B. A., Jun 1 2006, In : American Journal of Physiology - Renal Physiology. 290, 6, p. F1398-F1407

Research output: Contribution to journalArticle

26 Scopus citations

Concentration of Myo-inositol in skeletal muscle of the rat occurs without active transport

Molitoris, B. A., Karl, I. E. & Daughaday, W. H., Jan 1 1980, In : Journal of Clinical Investigation. 65, 4, p. 783-788 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

Convergence of apical and basolateral endocytic pathways for β2- microglobulin in LLC-PK1 cells

Cohen, M., Sundin, D. P., Dahl, R. & Molitoris, B. A., Jan 1 1995, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 268, 5 37-5, p. F829-F838

Research output: Contribution to journalArticle

10 Scopus citations

Cross-disciplinary biomarkers research: Lessons learned by the CKD biomarkers consortium

CKD Biomarkers Consortium, Jan 1 2015, In : Clinical Journal of the American Society of Nephrology. 10, 5, p. 894-902 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Cytokine-induced F-actin reorganization in endothelial cells involves RhoA activation

Campos, S. B., Ashworth, S. L., Wean, S., Hosford, M., Sandoval, R. M., Hallett, M. A., Atkinson, S. J. & Molitoris, B. A., Mar 1 2009, In : American Journal of Physiology - Renal Physiology. 296, 3, p. F487-F495

Research output: Contribution to journalArticle

39 Scopus citations
133 Scopus citations

Designing clinical trials in acute kidney injury

Molitoris, B. A., Okusa, M. D., Palevsky, P. M., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 842-843 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Design of clinical trials in acute kidney injury: Report from an NIDDK workshop on trial methodology

Palevsky, P. M., Molitoris, B. A., Okusa, M. D., Levin, A., Waikar, S. S., Wald, R., Chertow, G. M., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Faubel, S. G., Kellum, J. A., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 844-850 7 p.

Research output: Contribution to journalArticle

71 Scopus citations

Design of clinical trials in acute kidney injury: A report from an NIDDK workshop-prevention trials

Okusa, M. D., Molitoris, B. A., Palevsky, P. M., Chinchilli, V. M., Liu, K. D., Cheung, A. K., Weisbord, S. D., Faubel, S., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chawla, L. S., Kaufman, J. S., Devarajan, P. & 15 others, Toto, R. M., Hsu, C. Y., Greene, T. H., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 851-855 5 p.

Research output: Contribution to journalArticle

36 Scopus citations

Design of clinical trials in AKI: A report from an NIDDK workshop. Trials of patients with sepsis and in selected hospital settings

Molitoris, B. A., Okusa, M. D., Palevsky, P. M., Chawla, L. S., Kaufman, J. S., Devarajan, P., Toto, R. M., Hsu, C. Y., Greene, T. H., Faubel, S. G., Kellum, J. A., Wald, R., Chertow, G. M., Levin, A., Waikar, S. S., Murray, P. T., Parikh, C. R., Shaw, A. D., Go, A. S., Chinchilli, V. M. & 15 others, Liu, K. D., Cheung, A. K., Weisbord, S. D., Mehta, R. L., Stokes, J. B., Thompson, A. M., Taylor Thompson, B., Westenfelder, C. S., Tumlin, J. A., Warnock, D. G., Shah, S. V., Xie, Y., Duggan, E. G., Kimmel, P. L. & Star, R. A., May 1 2012, In : Clinical Journal of the American Society of Nephrology. 7, 5, p. 856-860 5 p.

Research output: Contribution to journalArticle

29 Scopus citations

Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified delphi process

Kellum, J. A., Mehta, R. L., Levin, A., Molitoris, B. A., Warnock, D. G., Shah, S. V., Joannidis, M. & Ronco, C., May 1 2008, In : Clinical Journal of the American Society of Nephrology. 3, 3, p. 887-894 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Dissociation and redistribution of Na+,K+-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion

Molitoris, B. A., Geerdes, A. & McIntosh, J. R., Aug 1991, In : Journal of Clinical Investigation. 88, 2, p. 462-469 8 p.

Research output: Contribution to journalArticle

Open Access
123 Scopus citations

Early monitoring of acute tubular necrosis in the rat kidney by 23Na-MRI

Atthe, B. K., Babsky, A. M., Hopewell, P. N., Phillips, C. L., Molitoris, B. A. & Bansal, N., Nov 2009, In : American Journal of Physiology - Renal Physiology. 297, 5, p. F1288-F1298

Research output: Contribution to journalArticle

21 Scopus citations
26 Scopus citations