Bruce Molitoris

  • 16112 Citations
  • 62 h-Index
1974 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

Filter
Article
2009

Soluble thrombomodulin protects ischemic kidneys

Sharfuddin, A. A., Sandoval, R. M., Berg, D. T., McDougal, G. E., Campos, S. B., Phillips, C. L., Jones, B. E., Gupta, A., Grinnell, B. W. & Molitoris, B. A., Mar 1 2009, In : Journal of the American Society of Nephrology. 20, 3, p. 524-534 11 p.

Research output: Contribution to journalArticle

89 Scopus citations

Techniques to study nephron function: Microscopy and imaging

Molitoris, B. A. & Sandoval, R. M., May 1 2009, In : Pflugers Archiv European Journal of Physiology. 458, 1, p. 203-209 7 p.

Research output: Contribution to journalArticle

11 Scopus citations
2008

Bacterial infection-mediated mucosal signalling induces local renal ischaemia as a defence against sepsis

Melican, K., Boekel, J., Månsson, L. E., Sandoval, R. M., Tanner, G. A., Källskog, Ö., Palm, F., Molitoris, B. A. & Richter-Dahlfors, A., Sep 16 2008, In : Cellular Microbiology. 10, 10, p. 1987-1998 12 p.

Research output: Contribution to journalArticle

73 Scopus citations

Development of a clinical research agenda for acute kidney injury using an international, interdisciplinary, three-step modified delphi process

Kellum, J. A., Mehta, R. L., Levin, A., Molitoris, B. A., Warnock, D. G., Shah, S. V., Joannidis, M. & Ronco, C., May 1 2008, In : Clinical Journal of the American Society of Nephrology. 3, 3, p. 887-894 8 p.

Research output: Contribution to journalArticle

60 Scopus citations

Evaluation and initial management of acute kidney injury

Himmelfarb, J., Joannidis, M., Molitoris, B., Schietz, M., Okusa, M. D., Warnock, D., Laghi, F., Goldstein, S. L., Prielipp, R., Parikh, C. R., Pannu, N., Lobo, S. M., Shah, S., D'Intini, V. & Kellum, J. A., Jul 2008, In : Clinical Journal of the American Society of Nephrology. 3, 4, p. 962-967 6 p.

Research output: Contribution to journalArticle

90 Scopus citations

Ischemic injury to kidney induces glomerular podocyte effacement and dissociation of slit diaphragm proteins Neph1 and ZO-1

Wagner, M. C., Rhodes, G., Wang, E., Pruthi, V., Arif, E., Saleem, M. A., Wean, S. E., Garg, P., Verma, R., Holzman, L. B., Gattone, V., Molitoris, B. A. & Nihalani, D., Dec 19 2008, In : Journal of Biological Chemistry. 283, 51, p. 35579-35589 11 p.

Research output: Contribution to journalArticle

52 Scopus citations
2007

Activated protein C ameliorates LPS-induced acute kidney injury and downregulates renal INOS and angiotensin 2

Gupta, A., Rhodes, G. J., Berg, D. T., Gerlitz, B., Molitoris, B. A. & Grinnell, B. W., Jul 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 1, p. F245-F254

Research output: Contribution to journalArticle

109 Scopus citations

Acute kidney injury network: Report of an initiative to improve outcomes in acute kidney injury

Mehta, R. L., Kellum, J. A., Shah, S. V., Molitoris, B. A., Ronco, C., Warnock, D. G., Levin, A., Bagga, A., Bakkaloglu, A., Bonventre, J. V., Burdmann, E. A., Chen, Y., Devarajan, P., D'Intini, V., Dobb, G., Durbin, C. G., Eckardt, K. U., Guerin, C., Herget-Rosenthal, S., Hoste, E. & 19 others, Joannidis, M., Kellum, J. A., Kirpalani, A., Lassnigg, A., Le Gall, J. R., Levin, A., Lombardi, R., Macias, W., Manthous, C., Mehta, R. L., Molitoris, B. A., Ronco, C., Schetz, M., Schortgen, F., Shah, S. V., Tan, P. S. K., Wang, H., Warnock, D. G. & Webb, S., Mar 1 2007, In : Critical Care. 11, R31.

Research output: Contribution to journalArticle

4250 Scopus citations

Improving outcomes from acute kidney injury (AKI): Report on an initiative

Ronco, C., Levin, A., Warnock, D. G., Metha, R. L., Kellum, J. A., Shah, S. & Molitoris, B. A., May 2007, In : International Journal of Artificial Organs. 30, 5, p. 373-376 4 p.

Research output: Contribution to journalArticle

42 Scopus citations

Organic cation transport in the rat kidney in vivo visualized by time-resolved two-photon microscopy

Hörbelt, M., Wotzlaw, C., Sutton, T. A., Molitoris, B. A., Philipp, T., Kribben, A., Fandrey, J. & Pietruck, F., Aug 1 2007, In : Kidney international. 72, 4, p. 422-429 8 p.

Research output: Contribution to journalArticle

14 Scopus citations

Rapid determination of renal filtration function using an optical ratiometric imaging approach

Yu, W., Sandoval, R. M. & Molitoris, B. A., Jun 1 2007, In : American Journal of Physiology - Renal Physiology. 292, 6, p. F1873-F1880

Research output: Contribution to journalArticle

77 Scopus citations

Real-time studies of the progression of bacterial infections and immediate tissue responses in live animals

Månsson, L. E., Melican, K., Boekel, J., Sandoval, R. M., Hautefort, I., Tanner, G. A., Molitoris, B. A. & Richter-dahlfors, A., Feb 1 2007, In : Cellular Microbiology. 9, 2, p. 413-424 12 p.

Research output: Contribution to journalArticle

69 Scopus citations

The normal kidney filters nephrotic levels of albumin retrieved by proximal tubule cells: Retrieval is disrupted in nephrotic states

Russo, L. M., Sandoval, R. M., McKee, M., Osicka, T. M., Collins, A. B., Brown, D., Molitoris, B. A. & Comper, W. D., Mar 13 2007, In : Kidney international. 71, 6, p. 504-513 10 p.

Research output: Contribution to journalArticle

286 Scopus citations
2006

A non-nephrotoxic gentamicin congener that retains antimicrobial efficacy

Sandoval, R. M., Reilly, J. P., Running, W., Campos, S. B., Santos, J. R., Phillips, C. L. & Molitoris, B. A., Oct 1 2006, In : Journal of the American Society of Nephrology. 17, 10, p. 2697-2705 9 p.

Research output: Contribution to journalArticle

29 Scopus citations

Cofilin mediates ATP depletion-induced endothelial cell actin alterations

Suurna, M. V., Ashworth, S. L., Hosford, M., Sandoval, R. M., Wean, S. E., Shah, B. M., Bamburg, J. R. & Molitoris, B. A., Jun 1 2006, In : American Journal of Physiology - Renal Physiology. 290, 6, p. F1398-F1407

Research output: Contribution to journalArticle

26 Scopus citations

Incidence and mortality of acute renal failure in Medicare beneficiaries, 1992 to 2001

Xue, J. L., Daniels, F., Star, R. A., Kimmel, P. L., Eggers, P. W., Molitoris, B. A., Himmelfarb, J. & Collins, A. J., Apr 1 2006, In : Journal of the American Society of Nephrology. 17, 4, p. 1135-1142 8 p.

Research output: Contribution to journalArticle

547 Scopus citations
11 Scopus citations

The role of statin therapy in patients with chronic kidney disease

Decker, B. S. & Molitoris, B. A., Jun 1 2006, In : Clinical Geriatrics. 14, 6, p. 29-34 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2005

Adenoviral vectors expressing human endostatin-angiostatin and soluble Tie2: Enhanced suppression of tumor growth and antiangiogenic effects in a prostate tumor model

Raikwar, S. P., Temm, C. J., Raikwar, N. S., Kao, C., Molitoris, B. A. & Gardner, T. A., Dec 2005, In : Molecular Therapy. 12, 6, p. 1091-1100 10 p.

Research output: Contribution to journalArticle

30 Scopus citations

Micropuncture gene delivery and intravital two-photon visualization of protein expression in rat kidney

Tanner, G. A., Sandoval, R. M., Molitoris, B. A., Bamburg, J. R. & Ashworth, S. L., Sep 1 2005, In : American Journal of Physiology - Renal Physiology. 289, 3 58-3, p. F638-F643

Research output: Contribution to journalArticle

36 Scopus citations

Quantitative intravital microscopy using a Generalized Polarity concept for kidney studies

Yu, W., Sandoval, R. M. & Molitoris, B. A., Nov 1 2005, In : American Journal of Physiology - Cell Physiology. 289, 5 58-5, p. C1197-C1208

Research output: Contribution to journalArticle

44 Scopus citations

Renal blood flow in sepsis: A complex issue

Molitoris, B. A., Aug 1 2005, In : Critical Care. 9, 4, p. 327-328 2 p.

Research output: Contribution to journalArticle

20 Scopus citations
2004

Actin cytoskeleton in ischemic acute renal failure

Molitoris, B. A., Harrington, J. T., Perrone, R., Jaber, B., Herman, I. M., Balakrishnan, V. S., Pahari, D. K. & Levey, A. S., Aug 2004, In : Kidney international. 66, 2, p. 871-883 13 p.

Research output: Contribution to journalArticle

53 Scopus citations

Endothelial injury and dysfunction: Role in the extension phase of acute renal failure

Molitoris, B. A. & Sutton, T. A., Aug 2004, In : Kidney international. 66, 2, p. 496-499 4 p.

Research output: Contribution to journalArticle

254 Scopus citations

Evolving basic concepts in ischemic injury

De Broe, M. E., Bonventre, J. V., Molitoris, B. A. & Haller, H., Aug 2004, In : Kidney international. 66, 2, 1 p.

Research output: Contribution to journalArticle

6 Scopus citations
73 Scopus citations

High pressure freezing and freeze substitution: Advances in renal research

Pennington, J. G., Miller, C. A., Sandoval, R., Gattone, V. H., Molitoris, B. & Bacallao, R. L., Sep 24 2004, In : Microscopy and Microanalysis. 10, SUPPL. 2, p. 1226-1227 2 p.

Research output: Contribution to journalArticle

Mechanism of Actin Polymerization in Cellular ATP Depletion

Atkinson, S. J., Hosford, M. A. & Molitoris, B. A., Feb 13 2004, In : Journal of Biological Chemistry. 279, 7, p. 5194-5199 6 p.

Research output: Contribution to journalArticle

87 Scopus citations

Renal ischemia induces tropomyosin dissociation-destabilizing microvilli microfilaments

Ashworth, S. L., Wean, S. E., Campos, S. B., Temm-Grove, C. J., Southgate, E. L., Vrhovski, B., Gunning, P., Weinberger, R. P. & Molitoris, B. A., May 1 2004, In : American Journal of Physiology - Renal Physiology. 286, 5 55-5, p. F988-F996

Research output: Contribution to journalArticle

18 Scopus citations

Uptake and trafficking of fluorescent conjugates of folic acid in intact kidney determined using intravital two-photon microscopy

Sandoval, R. M., Kennedy, M. D., Low, P. S. & Molitoris, B. A., Aug 1 2004, In : American Journal of Physiology - Cell Physiology. 287, 2 56-2, p. C517-C526

Research output: Contribution to journalArticle

114 Scopus citations
2003

ADF/cofilin mediates actin cytoskeletal alterations in LLC-PK cells during ATP depletion

Ashworth, S. L., Southgate, E. L., Sandoval, R. M., Meberg, P. J., Bamburg, J. R. & Molitoris, B. A., Apr 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 4 53-4, p. F852-F862

Research output: Contribution to journalArticle

45 Scopus citations
153 Scopus citations

Injury of the renal microvascular endothelium alters barrier function after ischemia

Sutton, T. A., Mang, H. E., Campos, S. B., Sandoval, R. M., Yoder, M. C. & Molitoris, B. A., Aug 1 2003, In : American Journal of Physiology - Renal Physiology. 285, 2 54-2, p. F191-F198

Research output: Contribution to journalArticle

239 Scopus citations

Urinary actin, interleukin-6, and interleukin-8 may predict sustained ARF after ischemic injury in renal allografts

Kwon, O., Molitoris, B. A., Pescovitz, M. & Kelly, K. J., May 1 2003, In : American Journal of Kidney Diseases. 41, 5, p. 1074-1087 14 p.

Research output: Contribution to journalArticle

91 Scopus citations
2002

Cardiovascular disease in patients with chronic kidney disease

Jaradat, M. I. & Molitoris, B. A., Nov 2002, In : Seminars in nephrology. 22, 6, p. 459-473 15 p.

Research output: Contribution to journalArticle

24 Scopus citations

Endothelial injury and dysfunction in ischemic acute renal failure

Molitoris, B. A., Sandoval, R. & Sutton, T. A., May 23 2002, In : Critical care medicine. 30, 5 SUPPL., p. S235-S240

Research output: Contribution to journalArticle

93 Scopus citations

Functional studies of the kidney of living animals using multicolor two-photon microscopy

Dunn, K. W., Sandoval, R. M., Kelly, K. J., Dagher, P. C., Tanner, G. A., Atkinson, S. J., Bacallao, R. L. & Molitoris, B. A., Sep 2002, In : American Journal of Physiology - Cell Physiology. 283, 3 52-3, p. C905-C916

Research output: Contribution to journalArticle

239 Scopus citations
56 Scopus citations

Microvascular endothelial injury and dysfunction during ischemic acute renal failure

Sutton, T. A., Fisher, C. J. & Molitoris, B. A., Nov 2002, In : Kidney international. 62, 5, p. 1539-1549 11 p.

Research output: Contribution to journalArticle

396 Scopus citations

Nucleotide depletion increases trafficking of gentamicin to the Golgi complex in LLC-PK1 cells

Sandoval, R. M., Bacallao, R. L., Dunn, K. W., Leiser, J. D. & Molitoris, B. A., Dec 1 2002, In : American Journal of Physiology - Renal Physiology. 283, 6 52-6, p. F1422-F1429

Research output: Contribution to journalArticle

7 Scopus citations
2001

Characteristics of EYFP-actin and visualization of actin dynamics during ATP depletion and repletion

Herget-Rosenthal, S., Hosford, M., Kribben, A., Atkinson, S. J., Sandoval, R. M. & Molitoris, B. A., Dec 1 2001, In : American Journal of Physiology - Cell Physiology. 281, 6 50-6, p. C1858-C1870

Research output: Contribution to journalArticle

19 Scopus citations

Erythropoietin requirements increase following hospitalization in end-stage renal disease patients

Yaqub, M. S., Leiser, J. & Molitoris, B. A., Dec 1 2001, In : American journal of nephrology. 21, 5, p. 390-396 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Gentamicin inhibits renal protein and phospholipid metabolism in rats: Implications involving intracellular trafficking

Sundin, D. P., Sandoval, R. & Molitoris, B. A., Jan 30 2001, In : Journal of the American Society of Nephrology. 12, 1, p. 114-123 10 p.

Research output: Contribution to journalArticle

65 Scopus citations

Ischemic injury induces ADF relocalization to the apical domain of rat proximal tubule cells

Ashworth, S. L., Sandoval, R. M., Hosford, M., Hamburg, J. R. & Molitoris, B. A., May 2001, In : American Journal of Physiology - Renal Physiology. 280, 5 49-5, p. F886-F894

Research output: Contribution to journalArticle

49 Scopus citations
2000

Gentamicin traffics rapidly and directly to the Golgi complex in LLC-PK1 cells

Sandoval, R. M., Dunn, K. W. & Molitoris, B. A., 2000, In : American Journal of Physiology - Renal Physiology. 279, 5 48-5, p. F884-F890

Research output: Contribution to journalArticle

30 Scopus citations
1999

Ischemia activates actin depolymerizing factor: Role in proximal tubule microvillar actin alterations

Schwartz, N., Hosford, M., Sandoval, R. M., Wagner, M. C., Atkinson, S. J., Bamburg, J. & Molitoris, B. A., Apr 1 1999, In : American Journal of Physiology - Renal Physiology. 276, 4 45-4, p. F544-F551

Research output: Contribution to journalArticle

79 Scopus citations

The role of cell adhesion molecules in ischemic acute renal failure

Molitoris, B. A. & Marrs, J., May 1999, In : American Journal of Medicine. 106, 5, p. 583-592 10 p.

Research output: Contribution to journalArticle

110 Scopus citations
1998

Aminoglycoside antibiotics traffic to the Golgi complex in LLC-PK1 cells

Sandoval, R., Leiser, J. & Molitoris, B. A., Feb 1 1998, In : Journal of the American Society of Nephrology. 9, 2, p. 167-174 8 p.

Research output: Contribution to journalArticle

69 Scopus citations
1997

Acute renal failure in the 21st century: Recommendations for management and outcomes assessment

DuBose, T. D., Warnock, D. G., Mehta, R. L., Bonventre, J. V., Hammerman, M. R., Molitoris, B. A., Paller, M. S., Siegel, N. J., Scherbenske, J. & Striker, G. E., May 1997, In : American Journal of Kidney Diseases. 29, 5, p. 793-799 7 p.

Research output: Contribution to journalArticle

89 Scopus citations

ATP depletion alters myosin Iβ cellular location in LLC-PK1 cells

Wagner, M. C. & Molitoris, B. A., Jan 1 1997, In : American Journal of Physiology - Cell Physiology. 272, 5 41-5, p. C1680-C1690

Research output: Contribution to journalArticle

29 Scopus citations