Bruce Molitoris

  • 15549 Citations
  • 62 h-Index
1974 …2019
If you made any changes in Pure, your changes will be visible here soon.

Publications 1974 2019

  • 15549 Citations
  • 62 h-Index
  • 223 Article
  • 20 Chapter
  • 2 Editorial
  • 1 Review article
Filter
Article
1998
137 Citations (Scopus)

Mechanisms of cellular injury in ischemic acute renal failure

Sutton, T. & Molitoris, B., 1998, In : Seminars in Nephrology. 18, 5, p. 490-497 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Actin Cytoskeleton
Cell Communication
Wounds and Injuries
Cell Polarity
1997
88 Citations (Scopus)

Acute renal failure in the 21st century: Recommendations for management and outcomes assessment

DuBose, T. D., Warnock, D. G., Mehta, R. L., Bonventre, J. V., Hammerman, M. R., Molitoris, B., Paller, M. S., Siegel, N. J., Scherbenske, J. & Striker, G. E., May 1997, In : American Journal of Kidney Diseases. 29, 5, p. 793-799 7 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Outcome Assessment (Health Care)
Renal Replacement Therapy
Mortality
National Institutes of Health (U.S.)
29 Citations (Scopus)
Myosin Type I
LLC-PK1 Cells
Adenosine Triphosphate
Actins
Microvilli
24 Citations (Scopus)

Cell biology of aminoglycoside nephrotoxicity: Newer aspects

Molitoris, B., 1997, In : Current Opinion in Nephrology and Hypertension. 6, 4, p. 384-388 5 p.

Research output: Contribution to journalArticle

Aminoglycosides
Endocytosis
Cell Biology
Low Density Lipoprotein Receptor-Related Protein-2
Golgi Apparatus
21 Citations (Scopus)

Cellular mechanism of aminoglycoside tolerance in long-term gentamicin treatment

Sundin, D. P., Meyer, C., Dahl, R., Geerdes, A., Sandoval, R. & Molitoris, B., 1997, In : American Journal of Physiology - Cell Physiology. 272, 4 41-4

Research output: Contribution to journalArticle

Aminoglycosides
Gentamicins
Membranes
Low Density Lipoprotein Receptor-Related Protein-2
Rats
74 Citations (Scopus)
Actin Cytoskeleton
Actins
Microfilament Proteins
Cell Polarity
Proteins
14 Citations (Scopus)
Actin Cytoskeleton
Actins
Cell Polarity
Proteins
Exocytosis
Actin Cytoskeleton
Actins
Cell Polarity
Proteins
Exocytosis
47 Citations (Scopus)

Role of the actin cytoskeleton in ischemia-induced cell injury and repair

Molitoris, B., Leiser, J. & Wagner, M., Dec 1997, In : Pediatric Nephrology. 11, 6, p. 761-767 7 p.

Research output: Contribution to journalArticle

Actin Cytoskeleton
Ischemia
Wounds and Injuries
Membranes
Adenosine Triphosphate
1996
54 Citations (Scopus)
Spectrin
Ankyrins
Adenosine Triphosphate
Octoxynol
LLC-PK1 Cells

Recovery of the actin cytoskeleton during cellular repair is independent of protein synthesis

Hosford, M., Sandoval, R. & Molitoris, B., 1996, In : Journal of Investigative Medicine. 44, 1

Research output: Contribution to journalArticle

Actin Cytoskeleton
Actins
Repair
Recovery
Proteins
31 Citations (Scopus)

Surface membrane polarity of proximal tubular cells: Alterations as a basis for malfunction

Molitoris, B. & Wagner, M., 1996, In : Kidney International. 49, 6, p. 1592-1597 6 p.

Research output: Contribution to journalArticle

Membranes
Actin Cytoskeleton
Membrane Proteins
Cell-Matrix Junctions
Membrane Lipids
Myosin Type I
Proximal Kidney Tubule
Myosins
Actins
Adenosine Triphosphate
1995
10 Citations (Scopus)
LLC-PK1 Cells
Gold
gold
proximal tubules
Molecular Weight
3 Citations (Scopus)

HWA-448 reduces gentamicin toxicity in LLC-PK1 cells

Ford, D. M., Thieme, R. E., Lamp, C. A., Covington, S. J. & Molitoris, B., 1995, In : Journal of Pharmacology and Experimental Therapeutics. 274, 1, p. 29-33 5 p.

Research output: Contribution to journalArticle

LLC-PK1 Cells
Gentamicins
Phospholipids
Cell Membrane
Enzymes
65 Citations (Scopus)

Plasma protein adsorption to highly permeable hemodialysis membranes

Clark, W. R., Macias, W. L., Molitoris, B. & Wang, N. H. L., 1995, In : Kidney International. 48, 2, p. 481-488 8 p.

Research output: Contribution to journalArticle

Adsorption
Renal Dialysis
Blood Proteins
Membranes
Bovine Serum Albumin
1994
180 Citations (Scopus)

Alterations in epithelial polarity and the pathogenesis of disease states

Fish, E. M. & Molitoris, B., 1994, In : New England Journal of Medicine. 330, 22, p. 1580-1588 9 p.

Research output: Contribution to journalArticle

Cell Polarity
Epithelial Cells
Disease Progression
Maintenance
23 Citations (Scopus)

Apically and basolaterally internalized aminoglycosides colocalize in LLC- PK1 lysosomes and alter cell function

Ford, D. M., Dahl, R. H., Lamp, C. A. & Molitoris, B., 1994, In : American Journal of Physiology - Cell Physiology. 266, 1 35-1

Research output: Contribution to journalArticle

Aminoglycosides
Lysosomes
Gentamicins
Membranes
LLC-PK1 Cells

Characterization of the beta2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B., 1994, In : The American journal of physiology. 267, 3 part 2

Research output: Contribution to journalArticle

proximal tubules
rats
cells
22 Citations (Scopus)

Characterization of the β2-microglobulin endocytic pathway in rat proximal tubule cells

Sundin, D. P., Cohen, M., Dahl, R., Falk, S. & Molitoris, B., Sep 1994, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 267, 3 36-3

Research output: Contribution to journalArticle

Microvilli
Gold
Membranes
Coated Vesicles
Proteins
30 Citations (Scopus)
Acidosis
Actin Cytoskeleton
Actins
Adenosine Triphosphate
Ischemia
20 Citations (Scopus)

Inherited diseases of the glomerular basement membrane

Bodziak, K. A., Hammond, W. S. & Molitoris, B., 1994, In : American Journal of Kidney Diseases. 23, 4, p. 605-618 14 p.

Research output: Contribution to journalArticle

Hereditary Nephritis
Glomerular Basement Membrane
Nail-Patella Syndrome
Hematuria
Kidney Transplantation
54 Citations (Scopus)

Membrane adsorption of β2-microglobulin: Equilibrium and kinetic characterization

Clark, W. R., Macias, W. L., Molitoris, B. & Wang, N. H. L., Oct 1994, In : Kidney International. 46, 4, p. 1140-1146 7 p.

Research output: Contribution to journalArticle

Adsorption
Membranes
Amyloidosis
Dialysis
Buffers
1993
39 Citations (Scopus)
Cell Polarity
Pathologic Processes
Actin Cytoskeleton
Cell Biology
Epithelium
32 Citations (Scopus)

Mechanism of ischemia-enhanced aminoglycoside binding and uptake by proximal tubule cells

Molitoris, B., Meyer, C., Dahl, R. & Geerdes, A., May 1993, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 264, 5 33-5

Research output: Contribution to journalArticle

Aminoglycosides
Gentamicins
Ischemia
Membranes
Phosphatidylinositols
61 Citations (Scopus)
Adenosine Triphosphatases
Adenosine Triphosphate
Ouabain
Membranes
LLC-PK1 Cells
1992
133 Citations (Scopus)
Cytoskeleton
Ischemia
Membranes
Octoxynol
Actin Cytoskeleton
5 Citations (Scopus)

Role of the actin cytoskeleton in ischemic injury

Molitoris, B., Dahl, R. & Geerdes, A., 1992, In : Chest. 101, 3 SUPPL.

Research output: Contribution to journalArticle

Cell Polarity
Intercellular Junctions
Actin Cytoskeleton
Actins
Ischemia
22 Citations (Scopus)

The potential role of ischemia in renal disease progression.

Molitoris, B., May 1992, In : Kidney international. Supplement. 36

Research output: Contribution to journalArticle

Sodium-Potassium-Exchanging ATPase
Membrane Lipids
Chronic Kidney Failure
Disease Progression
Membrane Proteins
1991
9 Citations (Scopus)
Microvilli
Membrane Proteins
Phospholipids
Membrane Fluidity
Gels
122 Citations (Scopus)

Dissociation and redistribution of Na+,K+-ATPase from its surface membrane actin cytoskeletal complex during cellular ATP depletion

Molitoris, B., Geerdes, A. & McIntosh, J. R., Aug 1991, In : Journal of Clinical Investigation. 88, 2, p. 462-469 8 p.

Research output: Contribution to journalArticle

Actins
Adenosine Triphosphate
Membranes
Actin Cytoskeleton
Detergents
112 Citations (Scopus)

Effect of reversible ATP depletion on tight-junction integrity in LLC-PK1 cells

Ellen Canfield, P., Geerdes, A. M. & Molitoris, B., 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 261, 6 30-6

Research output: Contribution to journalArticle

LLC-PK1 Cells
Tight Junctions
Adenosine Triphosphate
Mannitol
Antimycin A
138 Citations (Scopus)
Actin Cytoskeleton
Ischemia
Membranes
Membrane Proteins
Membrane Lipids
23 Citations (Scopus)

Myo-inositol uptake by rat cultured inner medullary collecting tubule cells: Effect of osmolality

Veis, J. H., Molitoris, B., Teitelbaum, I., Mansour, J. A. & Berl, T., 1991, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 260, 5 29-5

Research output: Contribution to journalArticle

Inositol
Osmolar Concentration
Cycloheximide
Nocodazole
Osmoregulation
58 Citations (Scopus)

New insights into the cell biology of ischemic acute renal failure

Molitoris, B., 1991, In : Journal of the American Society of Nephrology. 1, 12, p. 1263-1270 8 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Cell Biology
Membranes
Membrane Proteins
Membrane Lipids
1990
93 Citations (Scopus)

Alterations in the establishment and maintenance of epithelial cell polarity as a basis for disease processes

Molitoris, B. & Nelson, W. J., Jan 1990, In : Journal of Clinical Investigation. 85, 1, p. 3-9 7 p.

Research output: Contribution to journalArticle

19 Citations (Scopus)

Mild ischemia predisposes the S3 segment to gentamicin toxicity

Spiegel, D. M., Shanley, P. F. & Molitoris, B., Sep 1990, In : Kidney International. 38, 3, p. 459-464 6 p.

Research output: Contribution to journalArticle

Gentamicins
Ischemia
Kidney
Creatinine
Inulin
88 Citations (Scopus)

Role of microfilaments in maintenance of proximal tubule structural and functional integrity

Kellerman, P. S., Clark, R. A. F., Hoilien, C. A., Linas, S. L. & Molitoris, B., 1990, In : American Journal of Physiology - Renal Fluid and Electrolyte Physiology. 259, 2 28-2

Research output: Contribution to journalArticle

Actin Cytoskeleton
Maintenance
Cytochalasin D
Perfusion
Sodium
1989
41 Citations (Scopus)

Beta-2-Microglobulin-Associated amyloidosis in chronic hemodialysis patients with carpal tunnel syndrome

Ullian, M. E., Hammond, W. S., Alfrey, A. C., Schultz, A. & Molitoris, B., 1989, In : Medicine (United States). 68, 2, p. 107-115 9 p.

Research output: Contribution to journalArticle

beta 2-Microglobulin
Carpal Tunnel Syndrome
Synovial Membrane
Bone Diseases
Muscular Diseases
87 Citations (Scopus)

Citrate: A major factor in the toxicity of orally administered aluminum compounds

Molitoris, B., Froment, D. H., Mackenzie, T. A., Huffer, W. H. & Alfrey, A. C., 1989, In : Kidney International. 36, 6, p. 949-953 5 p.

Research output: Contribution to journalArticle

56 Citations (Scopus)
Ischemia
Membranes
Membrane Lipids
Glucose
Membrane Proteins
114 Citations (Scopus)

Ischemia-induced loss of epithelial polarity. Role of the tight junction

Molitoris, B., Falk, S. A. & Dahl, R. H., 1989, In : Journal of Clinical Investigation. 84, 4, p. 1334-1339 6 p.

Research output: Contribution to journalArticle

Tight Junctions
Ischemia
Membranes
Ruthenium Red
Lipids
56 Citations (Scopus)

Loss of epithelial polarity: A novel hypothesis for reduced proximal tubule Na+ transport following ischemic injury

Molitoris, B., Chan, L. K., Shapiro, J. I., Conger, J. D. & Falk, S. A., Feb 1989, In : Journal of Membrane Biology. 107, 2, p. 119-127 9 p.

Research output: Contribution to journalArticle

Membranes
Ischemia
Wounds and Injuries
Adenosine Triphosphatases
Proximal Kidney Tubule
65 Citations (Scopus)

Markedly increased clearance of vancomycin during hemodialysis using polysulfone dialyzers

Lanese, D. M., Alfrey, P. S. & Molitoris, B., 1989, In : Kidney International. 35, 6, p. 1409-1412 4 p.

Research output: Contribution to journalArticle

Vancomycin
Renal Dialysis
polysulfone P 1700
117 Citations (Scopus)

Site and mechanism of enhanced gastrointestinal absorption of aluminum by citrate

Froment Ph., D., Molitoris, B., Buddington, B., Miller, N. & Alfrey, A. C., 1989, In : Kidney International. 36, 6, p. 978-984 7 p.

Research output: Contribution to journalArticle

Aluminum
Tight Junctions
Ruthenium Red
aluminum citrate
Gastrointestinal Absorption
6 Citations (Scopus)

The role of aluminum in the pathogenesis of anemia in an outpatient hemodialysis population

Yuan, B., Klein, M. H., Contiguglia, R. S., Mishell, J. L., Seligman, P. A., Miller, N. L., Molitoris, B., Alfrey, A. C. & Shapiro, J. I., 1989, In : Renal Failure. 11, 2-3, p. 91-96 6 p.

Research output: Contribution to journalArticle

Aluminum
Renal Dialysis
Anemia
Outpatients
Population
1988
62 Citations (Scopus)

Characterization of ischemia-induced loss of epithelial polarity

Molitoris, B., Hoilien, C. A., Dahl, R., Ahnen, D. J., Wilson, P. D. & Kim, J., Dec 1988, In : Journal of Membrane Biology. 106, 3, p. 233-242 10 p.

Research output: Contribution to journalArticle

Ischemia
Proximal Kidney Tubule
Membranes
Membrane Lipids
Adenosine Triphosphatases
23 Citations (Scopus)

Rapid removal of DFO-chelated aluminum during hemodialysis using polysulfone dialyzers

Molitoris, B., Alfrey, A. C., Alfrey, P. S. & Miller, N. L., 1988, In : Kidney International. 34, 1, p. 98-101 4 p.

Research output: Contribution to journalArticle

Deferoxamine
Aluminum
Renal Dialysis
polysulfone P 1700
Dialysis
1987
15 Citations (Scopus)

Bilateral congenital renal arteriovenous fistulas

Ullian, M. E. & Molitoris, B., 1987, In : Clinical Nephrology. 27, 6, p. 293-297 5 p.

Research output: Contribution to journalArticle

Arteriovenous Fistula
Fistula
Kidney
Hypertension
Renin
27 Citations (Scopus)

Efficacy of intramuscular and intraperitoneal deferoxamine for aluminium chelation

Molitoris, B., Alfrey, P. S., Miller, N. L., Hasbargen, J. A., Kaehney, W. D. & Smith, B. J., 1987, In : Kidney International. 31, 4, p. 986-991 6 p.

Research output: Contribution to journalArticle

Deferoxamine
Aluminum
Renal Dialysis
Serum
Continuous Ambulatory Peritoneal Dialysis