Carmella Evans-Molina

  • 2632 Citations
  • 25 h-Index
20062020

Research output per year

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Publications

  • 2632 Citations
  • 25 h-Index
  • 57 Article
  • 16 Comment/debate
  • 16 Review article
  • 4 Letter

Abnormalities in proinsulin processing in islets from individuals with longstanding T1D

Sims, E. K., Syed, F., Nyalwidhe, J., Bahnson, H. T., Haataja, L., Speake, C., Morris, M. A., Balamurugan, A. N., Mirmira, R. G., Nadler, J., Mastracci, T. L., Arvan, P., Greenbaum, C. J. & Evans-Molina, C., Nov 2019, In : Translational Research. 213, p. 90-99 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

A case of calciphylaxis in a patient with hypoparathyroidism and normal renal function

Erdel, B. L., Juneja, R. & Evans-Molina, C., Jun 1 2014, In : Endocrine Practice. 20, 6, p. e102-e105

Research output: Contribution to journalArticle

6 Scopus citations

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: A unique presentation of a rare tumor

Saeed, Z., Taleb, S. & Evans-Molina, C., Dec 1 2016, In : BMC Cancer. 16, 1, 930.

Research output: Contribution to journalArticle

2 Scopus citations

Achieving "PeaK-A" insulin secretion

Evans-Molina, C. & Mirmira, R. G., May 1 2013, In : Diabetes. 62, 5, p. 1389-1390 2 p.

Research output: Contribution to journalComment/debate

Adenosine and seizures - What's the big fat deal?

Evans-Molina, C., Jul 20 2011, In : Science translational medicine. 3, 92, 92ec113.

Research output: Contribution to journalComment/debate

1 Scopus citations

A hepatitis C mouse model that isn't chopped liver

Evans-Molina, C., Jun 22 2011, In : Science translational medicine. 3, 88, 88ec94.

Research output: Contribution to journalComment/debate

Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes

Ocaña, G. J., Sims, E. K., Watkins, R. A., Ragg, S., Mather, K. J., Oram, R. A., Mirmira, R. G., DiMeglio, L. A., Blum, J. S. & Evans-Molina, C., Jan 2019, In : PloS one. 14, 1, e0208456.

Research output: Contribution to journalArticle

2 Scopus citations

A new FIX for hemophilia B

Evans-Molina, C., Jan 11 2012, In : Science translational medicine. 4, 116, 116ec5.

Research output: Contribution to journalComment/debate

An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic β cells

Sturek, J. M., Castle, J. D., Trace, A. P., Page, L. C., Castle, A. M., Evans-Molina, C., Parks, J. S., Mirmira, R. G. & Hedrick, C. C., Jul 1 2010, In : Journal of Clinical Investigation. 120, 7, p. 2575-2589 15 p.

Research output: Contribution to journalArticle

91 Scopus citations

A snooze button for the biological clock

Evans-Molina, C., Aug 17 2011, In : Science translational medicine. 3, 96, 96ec131.

Research output: Contribution to journalComment/debate

Associations of HbA1c with the timing of C-peptide responses during the oral glucose tolerance test at the diagnosis of type 1 diabetes

Type 1 Diabetes Trial Net and Diabetes Prevention Trial-Type-1 (DPT-1) Study Groups, Jun 2019, In : Pediatric Diabetes. 20, 4, p. 408-413 6 p.

Research output: Contribution to journalArticle

A sweet spot for kallikrein in intracerebral hemorrhage

Evans-Molina, C., Mar 2 2011, In : Science translational medicine. 3, 72, 72ec27.

Research output: Contribution to journalComment/debate

A sweet success for diabetes research

Evans-Molina, C., Sep 21 2011, In : Science translational medicine. 3, 101, 101ec153.

Research output: Contribution to journalComment/debate

Beta cell function in type 1 diabetes determined from clinical and fasting biochemical variables

the Type 1 Diabetes TrialNet Study Group & the Immune Tolerance Network Study Group, Jan 1 2019, In : Diabetologia. 62, 1, p. 33-40 8 p.

Research output: Contribution to journalArticle

4 Scopus citations

Beta cells in type 1 diabetes: mass and function; sleeping or dead?

Oram, R. A., Sims, E. K. & Evans-Molina, C., Apr 1 2019, In : Diabetologia. 62, 4, p. 567-577 11 p.

Research output: Contribution to journalReview article

14 Scopus citations

Biomarkers of islet beta cell stress and death in type 1 diabetes

Sims, E. K., Evans-Molina, C., Tersey, S. A., Eizirik, D. L. & Mirmira, R. G., Nov 1 2018, In : Diabetologia. 61, 11, p. 2259-2265 7 p.

Research output: Contribution to journalReview article

6 Scopus citations

Biomarkers of β-Cell Stress and Death in Type 1 Diabetes

Mirmira, R. G., Sims, E. K., Syed, F. & Evans-Molina, C., Oct 1 2016, In : Current Diabetes Reports. 16, 10, 95.

Research output: Contribution to journalReview article

13 Scopus citations

Bisphenol A, obesity, and type 2 diabetes mellitus: Genuine concern or unnecessary preoccupation?

Mirmira, P. & Evans-Molina, C., Jul 2014, In : Translational Research. 164, 1, p. 13-21 9 p.

Research output: Contribution to journalReview article

37 Scopus citations

CD40 promotes mhc class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity

Morris, D. L., Oatmen, K. E., Mergian, T. A., Cho, K. W., Delproposto, J. L., Singer, K., Evans-Molina, C., O’Rourke, R. W. & Lumeng, C. N., Jun 2016, In : Journal of Leukocyte Biology. 99, 6, p. 1107-1119 13 p.

Research output: Contribution to journalArticle

16 Scopus citations

Chronic high fat feeding restricts islet mRNA translation initiation independently of ER stress via DNA damage and p53 activation

Hatanaka, M., Anderson-Baucum, E., Lakhter, A., Kono, T., Maier, B., Tersey, S. A., Tanizawa, Y., Evans-Molina, C., Mirmira, R. G. & Sims, E. K., Dec 1 2017, In : Scientific reports. 7, 1, 3758.

Research output: Contribution to journalArticle

5 Scopus citations

Chronic pain. Epigenetic modulation of CNS pathways: What a pain!

Evans-Molina, C., Dec 7 2011, In : Science translational medicine. 3, 112, 112ec198.

Research output: Contribution to journalComment/debate

Combination Immunotherapy for Type 1 Diabetes

Bone, R. N. & Evans-Molina, C., Jul 1 2017, In : Current Diabetes Reports. 17, 7, 50.

Research output: Contribution to journalReview article

7 Scopus citations

Development of insulin-producing cells from primitive biologic precursors

Evans-Molina, C., Vestermark, G. L. & Mirmira, R. G., Feb 1 2009, In : Current Opinion in Organ Transplantation. 14, 1, p. 56-63 8 p.

Research output: Contribution to journalReview article

13 Scopus citations

Diabetes: Mayday, mayday, mayday! Answering the distress call of the β cell

Evans-Molina, C., Feb 8 2012, In : Science translational medicine. 4, 120

Research output: Contribution to journalComment/debate

Divergent compensatory responses to high-fat diet between C57Bl6/J and c57BlKS/J inbred mouse strains

Sims, E. K., Hatanaka, M., Morris, D. L., Tersey, S. A., Kono, T., Chaudry, Z. Z., Day, K. H., Moss, D. R., Stull, N. D., Mirmira, R. G. & Evans-Molina, C., Dec 15 2013, In : American Journal of Physiology - Endocrinology and Metabolism. 305, 12, p. E1495-E1511

Research output: Contribution to journalArticle

21 Scopus citations

Dysglycemia and Index60 as prediagnostic end points for type 1 diabetes prevention trials

Nathan, B. M., Boulware, D., Geyer, S., Atkinson, M. A., Colman, P., Goland, R., Russell, W., Wentworth, J. M., Wilson, D. M., Evans-Molina, C., Wherrett, D., Skyler, J. S., Moran, A. & Sosenko, J. M., Nov 1 2017, In : Diabetes care. 40, 11, p. 1494-1499 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

Effect of oral insulin on prevention of diabetes in relatives of patients with type 1 diabetes: A randomized clinical trial

Writing Committee for the Type 1 Diabetes TrialNet Oral Insulin Study Group, Nov 21 2017, In : JAMA - Journal of the American Medical Association. 318, 19, p. 1891-1902 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

Elevations in circulating methylated and unmethylated preproinsulin DNA in new-onset type 1 diabetes

Fisher, M. M., Watkins, R. A., Blum, J., Evans-Molina, C., Chalasani, N., Dimeglio, L. A., Mather, K. J., Tersey, S. A. & Mirmira, R. G., Nov 2015, In : Diabetes. 64, 11, p. 3867-3872 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Elevations in the fasting serum Proinsulin-to-C-peptide ratio precede the onset of type 1 diabetes

Sims, E. K., Chaudhry, Z., Watkins, R., Syed, F., Blum, J., Ouyang, F., Perkins, S. M., Mirmira, R. G., Sosenko, J., DiMeglio, L. A. & Evans-Molina, C., Sep 1 2016, In : Diabetes care. 39, 9, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

35 Scopus citations

Endoplasmic reticulum stress alters ryanodine receptor function in the murine pancreatic cell

Yamamoto, W. R., Bone, R. N., Sohn, P., Syed, F., Reissaus, C. A., Mosley, A. L., Wijeratne, A. B., True, J. D., Tong, X., Kono, T. & Evans-Molina, C., Jan 4 2019, In : Journal of Biological Chemistry. 294, 1, p. 168-181 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

Established and emerging biomarkers for the prediction of type 1 diabetes: A systematic review

Watkins, R. A., Evans-Molina, C., Blum, J. S. & Dimeglio, L. A., Aug 2014, In : Translational Research. 164, 2, p. 110-121 12 p.

Research output: Contribution to journalReview article

36 Scopus citations

Excess BMI in childhood: A modifiable risk factor for type 1 diabetes development?

Ferrara, C. T., Geyer, S. M., Liu, Y. F., Evans-Molina, C., Libman, I. M., Besser, R., Becker, D. J., Rodriguez, H., Moran, A., Gitelman, S. E. & Redondo, M. J., May 1 2017, In : Diabetes care. 40, 5, p. 698-701 4 p.

Research output: Contribution to journalArticle

24 Scopus citations

Fetal DNA: A needle in the haystack

Evans-Molina, C., Mar 30 2011, In : Science translational medicine. 3, 76, 76ec43.

Research output: Contribution to journalComment/debate

Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats

Blue, E. K., Ballman, K., Boyle, F., Oh, E., Kono, T., Quinney, S. K., Thurmond, D. C., Evans-Molina, C. & Haneline, L. S., Feb 11 2015, In : Pediatric Research. 77, 2, p. 316-325 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

From immunobiology to β-cell biology: The changing perspective on type 1 diabetes

Maganti, A., Evans-Molina, C. & Mirmira, R. G., Jan 1 2014, In : Islets. 6, 2, p. e28778-1-e28778-5 e28778.

Research output: Contribution to journalArticle

20 Scopus citations

Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets

Evans-Molina, C., Garmey, J. C., Ketchum, R., Brayman, K. L., Deng, S. & Mirmira, R. G., Mar 1 2007, In : Diabetes. 56, 3, p. 827-835 9 p.

Research output: Contribution to journalArticle

49 Scopus citations

High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: Involvement of peroxisome proliferator-activated receptor γ signaling

So, W. Y., Cheng, Q., Chen, L., Evans-Molina, C., Xu, A., Lam, K. S. L. & Leung, P. S., Nov 1 2013, In : Diabetes. 62, 11, p. 3751-3759 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

HLA-DRB115:01-DQA101:02-DQB106:02 haplotype protects autoantibody-positive relatives from type 1 diabetes throughout the stages of disease progression

Pugliese, A., Boulware, D., Yu, L., Babu, S., Steck, A. K., Becker, D., Rodriguez, H., Di Meglio, L., Evans-Molina, C., Harrison, L. C., Schatz, D., Palmer, J. P., Greenbaum, C., Eisenbarth, G. S. & Sosenko, J. M., Apr 2016, In : Diabetes. 65, 4, p. 1109-1119 11 p.

Research output: Contribution to journalArticle

18 Scopus citations

Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: Analysis of hASC-derived paracrine effectors

Kono, T. M., Sims, E. K., Moss, D. R., Yamamoto, W., Ahn, G., Diamond, J., Tong, X., Day, K. H., Territo, P. R., Hanenberg, H., Traktuev, D. O., March, K. L. & Evans-Molina, C., Jul 2014, In : STEM CELLS. 32, 7, p. 1831-1842 12 p.

Research output: Contribution to journalArticle

34 Scopus citations

Impaired store-operated calcium entry and STIM1 loss lead to reduced insulin secretion and increased endoplasmic reticulum stress in the diabetic B-cell

Gilon, P., Roe, M. W., Evans-Molina, C., Kono, T., Tong, X., Taleb, S., Bone, R. N., Iida, H., Lee, C. C. & Sohn, P., Nov 1 2018, In : Diabetes. 67, 11, p. 2293-2304 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Inflammatory stress of pancreatic beta cells drives release of extracellular heat-shock protein 90α

Ocaña, G. J., Pérez, L., Guindon, L., Deffit, S. N., Evans-Molina, C., Thurmond, D. C. & Blum, J. S., Jun 2017, In : Immunology. 151, 2, p. 198-210 13 p.

Research output: Contribution to journalArticle

5 Scopus citations

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model

Tersey, S. A., Nishiki, Y., Templin, A. T., Cabrera, S. M., Stull, N. D., Colvin, S. C., Evans-Molina, C., Rickus, J. L., Maier, B. & Mirmira, R. G., Apr 1 2012, In : Diabetes. 61, 4, p. 818-827 10 p.

Research output: Contribution to journalArticle

174 Scopus citations

Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of Type 1 diabetes

Filgueiras, L. R., Brandt, S. L., Wang, S., Wang, Z., Morris, D. L., Evans-Molina, C., Mirmira, R. G., Jancar, S. & Serezani, C. H., Jan 27 2015, In : Science Signaling. 8, 361

Research output: Contribution to journalArticle

31 Scopus citations

Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling

Ogihara, T., Chuang, J. C., Vestermark, G. L., Garmey, J. C., Ketchum, R. J., Huang, X., Brayman, K. L., Thorner, M. O., Repa, J. J., Mirmira, R. G. & Evans-Molina, C., Feb 19 2010, In : Journal of Biological Chemistry. 285, 8, p. 5392-5404 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Loss of diurnal oscillatory rhythms in gut microbiota correlates with changes in circulating metabolites in type 2 diabetic db/db mice

Beli, E., Prabakaran, S., Krishnan, P., Evans-Molina, C. & Grant, M. B., Oct 2019, In : Nutrients. 11, 10, 2310.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Lost in translation: Endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus

Evans-Molina, C., Hatanaka, M. & Mirmira, R. G., Sep 2013, In : Diabetes, Obesity and Metabolism. 15, S3, p. 159-169 11 p.

Research output: Contribution to journalReview article

27 Scopus citations

Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation

Hylek, E. M., Evans-Molina, C., Shea, C., Henault, L. E. & Regan, S., May 1 2007, In : Circulation. 115, 21, p. 2689-2696 8 p.

Research output: Contribution to journalArticle

813 Scopus citations

MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells

Sims, E. K., Lakhter, A. J., Anderson-Baucum, E., Kono, T., Tong, X. & Evans-Molina, C., Jun 1 2017, In : Diabetologia. 60, 6, p. 1057-1065 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
13 Scopus citations