Carmella Evans-Molina

  • 2734 Citations
  • 26 h-Index
20062020

Research output per year

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Publications

  • 2734 Citations
  • 26 h-Index
  • 62 Article
  • 17 Review article
  • 16 Comment/debate
  • 5 Letter

Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling

Ogihara, T., Chuang, J. C., Vestermark, G. L., Garmey, J. C., Ketchum, R. J., Huang, X., Brayman, K. L., Thorner, M. O., Repa, J. J., Mirmira, R. G. & Evans-Molina, C., Feb 19 2010, In : Journal of Biological Chemistry. 285, 8, p. 5392-5404 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Loss of diurnal oscillatory rhythms in gut microbiota correlates with changes in circulating metabolites in type 2 diabetic db/db mice

Beli, E., Prabakaran, S., Krishnan, P., Evans-Molina, C. & Grant, M. B., Oct 2019, In : Nutrients. 11, 10, 2310.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Lost in translation: Endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus

Evans-Molina, C., Hatanaka, M. & Mirmira, R. G., Sep 2013, In : Diabetes, Obesity and Metabolism. 15, S3, p. 159-169 11 p.

Research output: Contribution to journalReview article

28 Scopus citations

Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation

Hylek, E. M., Evans-Molina, C., Shea, C., Henault, L. E. & Regan, S., May 1 2007, In : Circulation. 115, 21, p. 2689-2696 8 p.

Research output: Contribution to journalArticle

823 Scopus citations

MicroRNA 21 targets BCL2 mRNA to increase apoptosis in rat and human beta cells

Sims, E. K., Lakhter, A. J., Anderson-Baucum, E., Kono, T., Tong, X. & Evans-Molina, C., Jun 1 2017, In : Diabetologia. 60, 6, p. 1057-1065 9 p.

Research output: Contribution to journalArticle

23 Scopus citations
13 Scopus citations

Nucleic acid biomarkers of β cell stress and death in type 1 diabetes

Syed, F. & Evans-Molina, C., Aug 1 2016, In : Current Opinion in Endocrinology, Diabetes and Obesity. 23, 4, p. 312-317 6 p.

Research output: Contribution to journalReview article

4 Scopus citations

Obesity. Yo-yo dieting: Biology or behavior?

Evans-Molina, C., Nov 9 2011, In : Science translational medicine. 3, 108, 108ec180.

Research output: Contribution to journalComment/debate

Palmitate induces mRNA translation and increases ER protein load in islet ß-cells via activation of the mammalian target of rapamycin pathway

Hatanaka, M., Maier, B., Sims, E. K., Templin, A. T., Kulkarni, R. N., Evans-Molina, C. & Mirmira, R. G., Oct 1 2014, In : Diabetes. 63, 10, p. 3404-3415 12 p.

Research output: Contribution to journalArticle

28 Scopus citations

Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell

Johnson, J. S., Kono, T., Tong, X., Yamamoto, W. R., Zarain-Herzberg, A., Merrins, M. J., Satin, L. S., Gilon, P. & Evans-Molina, C., Nov 21 2014, In : Journal of Biological Chemistry. 289, 47, p. 32798-32810 13 p.

Research output: Contribution to journalArticle

21 Scopus citations

Peroxisome proliferator-activated receptor γ activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

Evans-Molina, C., Robbins, R. D., Kono, T., Tersey, S. A., Vestermark, G. L., Nunemaker, C. S., Garmey, J. C., Deering, T. G., Keller, S. R., Maier, B. & Mirmira, R. G., Apr 1 2009, In : Molecular and cellular biology. 29, 8, p. 2053-2067 15 p.

Research output: Contribution to journalArticle

96 Scopus citations

Persistent elevations in circulating INS DNA among subjects with longstanding type 1 diabetes

Neyman, A., Nelson, J., Tersey, S. A., Mirmira, R. G., Evans-Molina, C. & Sims, E. K., Jan 2019, In : Diabetes, Obesity and Metabolism. 21, 1, p. 95-102 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress

Kono, T., Ahn, G., Moss, D. R., Gann, L., Zarain-Herzberg, A., Nishiki, Y., Fueger, P. T., Ogihara, T. & Evans-Molina, C., Jan 1 2012, In : Molecular Endocrinology. 26, 2, p. 257-271 15 p.

Research output: Contribution to journalArticle

Open Access
67 Scopus citations

Profiling of RNAs from human islet-derived exosomes in a model of type 1 diabetes

Krishnan, P., Syed, F., Kang, N. J., Mirmira, R. G. & Evans-Molina, C., Dec 1 2019, In : International journal of molecular sciences. 20, 23, 5903.

Research output: Contribution to journalArticle

Open Access

Proinsulin and heat shock protein 90 as biomarkers of beta-cell stress in the early period after onset of type 1 diabetes

Watkins, R. A., Evans-Molina, C., Terrell, J. K., Day, K. H., Guindon, L., Restrepo, I. A., Mirmira, R., Blum, J. & DiMeglio, L., Feb 1 2016, In : Translational Research. 168, p. 96-106.e1

Research output: Contribution to journalArticle

28 Scopus citations

Proinsulin secretion is a persistent feature of type 1 diabetes

Sims, E. K., Bahnson, H. T., Nyalwidhe, J., Haataja, L., Davis, A. K., Speake, C., DiMeglio, L. A., Blum, J., Morris, M. A., Mirmira, R. G., Nadler, J., Mastracci, T. L., Marcovina, S., Qian, W. J., Yi, L., Swensen, A. C., Yip-Schneider, M., Schmidt, C. M., Considine, R. V., Arvan, P. & 2 others, Greenbaum, C. J. & Evans-Molina, C., Feb 1 2019, In : Diabetes care. 42, 2, p. 258-264 7 p.

Research output: Contribution to journalArticle

16 Scopus citations

Proinsulin secretion is a persistent feature of type 1 diabetes. Diabetes care 2019;42:258–264

Sims, E. K., Bahnson, H. T., Nyalwidhe, J., Haataja, L., Davis, A. K., Speake, C., DiMeglio, L. A., Blum, J., Morris, M. A., Mirmira, R. G., Nadler, J., Mastracci, T. L., Marcovina, S., Qian, W. J., Yi, L., Swensen, A. C., Yip-Schneider, M., Max Schmidt, C., Considine, R. V., Arvan, P. & 2 others, Greenbaum, C. J. & Evans-Molina, C., May 1 2019, In : Diabetes care. 42, 5, p. E85-E86

Research output: Contribution to journalLetter

Open Access
2 Scopus citations

Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy

Rajashekhar, G., Ramadan, A., Abburi, C., Callaghan, B., Traktuev, D. O., Evans-Molina, C., Maturi, R., Harris, A., Kern, T. S. & March, K. L., Jan 9 2014, In : PLoS ONE. 9, 1, e84671.

Research output: Contribution to journalArticle

48 Scopus citations

Response to letter by Testa et al [2]

Hylek, E. M., Henault, L. E., Evans-Molina, C., Shea, C. & Regan, S., Dec 1 2006, In : Stroke. 37, 12, 1 p.

Research output: Contribution to journalLetter

1 Scopus citations

Restructuring of the gut microbiome by intermittent fasting prevents retinopathy and prolongs survival in db/db mice

Beli, E., Yan, Y., Moldovan, L., Vieira, C. P., Gao, R., Duan, Y., Prasad, R., Bhatwadekar, A., White, F. A., Townsend, S. D., Chan, L., Ryan, C. N., Morton, D., Moldovan, E. G., Chu, F. I., Oudit, G. Y., Derendorf, H., Adorini, L., Wang, X. X., Evans-Molina, C. & 7 others, Mirmira, R. G., Boulton, M. E., Yoder, M. C., Li, Q., Levi, M., Busik, J. V. & Grant, M. B., Sep 1 2018, In : Diabetes. 67, 9, p. 1867-1879 13 p.

Research output: Contribution to journalArticle

33 Scopus citations

Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1

Francis, J., Babu, D. A., Deering, T. G., Chakrabarti, S. K., Garmey, J. C., Evans-Molina, C., Taylor, D. G. & Mirmira, R. G., Dec 1 2006, In : Molecular Endocrinology. 20, 12, p. 3133-3145 13 p.

Research output: Contribution to journalArticle

13 Scopus citations

SERCA2 deficiency impairs pancreatic β-cell function in response to diet-induced obesity

Tong, X., Kono, T., Anderson-Baucum, E. K., Yamamoto, W., Gilon, P., Lebeche, D., Day, R. N., Shull, G. E. & Evans-Molina, C., Oct 1 2016, In : Diabetes. 65, 10, p. 3039-3052 14 p.

Research output: Contribution to journalArticle

27 Scopus citations

Serum miR-204 is an early biomarker of type 1 diabetes-associated pancreatic beta-cell loss

Xu, G., Thielen, L. A., Chen, J., Grayson, T. B., Grimes, T., Bridges, S. L., Tse, H. M., Smith, B., Patel, R., Li, P., Evans-Molina, C., Ovalle, F. & Shalev, A., Oct 1 2019, In : American journal of physiology. Endocrinology and metabolism. 317, 4, p. E723-E730

Research output: Contribution to journalArticle

1 Scopus citations

SET7/9 enzyme regulates cytokine-induced expression of inducible nitric-oxide synthase through methylation of Lysine 4 at histone 3 in the islet β cell

Fujimaki, K., Ogihara, T., Morris, D. L., Oda, H., Iida, H., Fujitani, Y., Mirmira, R. G., Evans-Molina, C. & Watada, H., Jul 3 2015, In : Journal of Biological Chemistry. 290, 27, p. 16607-16618 12 p.

Research output: Contribution to journalArticle

14 Scopus citations

Shock wave lithotripsy targeting of the kidney and pancreas does not increase the severity of metabolic syndrome in a porcine model

Handa, R. K., Evan, A. P., Connors, B. A., Johnson, C. D., Liu, Z., Alloosh, M., Sturek, M., Evans-Molina, C., Mandeville, J. A., Gnessin, E. & Lingeman, J. E., Oct 1 2014, In : Journal of Urology. 192, 4, p. 1257-1265 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Sirtuin 6 regulates glucose-stimulated insulin secretion in mouse pancreatic beta cells

Xiong, X., Wang, G., Tao, R., Wu, P., Kono, T., Li, K., Ding, W. X., Tong, X., Tersey, S. A., Harris, R. A., Mirmira, R. G., Evans-Molina, C. & Dong, X. C., Jan 1 2016, In : Diabetologia. 59, 1, p. 151-160 10 p.

Research output: Contribution to journalArticle

25 Scopus citations

Smoking and the risk of type 2 diabetes

Maddatu, J., Anderson-Baucum, E. & Evans-Molina, C., Jun 1 2017, In : Translational Research. 184, p. 101-107 7 p.

Research output: Contribution to journalReview article

25 Scopus citations

Sperm find culture

Evans-Molina, C., Apr 27 2011, In : Science translational medicine. 3, 80, 80ec60.

Research output: Contribution to journalComment/debate

Spotlight on the silent lady killer

Evans-Molina, C., Oct 12 2011, In : Science translational medicine. 3, 104

Research output: Contribution to journalComment/debate

STEAP4 expression in human islets is associated with differences in body mass index, sex, HbA1c, and inflammation

Gordon, H. M., Majithia, N., MacDonald, P. E., Fox, J. E. M., Sharma, P. R., Byrne, F. L., Hoehn, K. L., Evans-Molina, C., Langman, L., Brayman, K. L. & Nunemaker, C. S., Jun 1 2017, In : Endocrine. 56, 3, p. 528-537 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

Streptozotocin is equally diabetogenic whether administered to fed or fasted mice

Chaudhry, Z. Z., Morris, D. L., Moss, D. R., Sims, E. K., Chiong, Y., Kono, T. & Evans-Molina, C., Dec 17 2013, In : Laboratory Animals. 47, 4, p. 257-265 9 p.

Research output: Contribution to journalArticle

25 Scopus citations

The Effect of Age on the Progression and Severity of Type 1 Diabetes: Potential Effects on Disease Mechanisms

Leete, P., Mallone, R., Richardson, S. J., Sosenko, J. M., Redondo, M. J. & Evans-Molina, C., Nov 1 2018, In : Current Diabetes Reports. 18, 11, 115.

Research output: Contribution to journalReview article

7 Scopus citations

The influence of body mass index and age on C-peptide at the diagnosis of type 1 diabetes in children who participated in the diabetes prevention trial-type 1

Sosenko, J. M., Geyer, S., Skyler, J. S., Rafkin, L. E., Ismail, H. M., Libman, I. M., Liu, Y. F., DiMeglio, L. A., Evans-Molina, C. & Palmer, J. P., May 2018, In : Pediatric Diabetes. 19, 3, p. 403-409 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

The influence of type 2 diabetes-associated factors on type 1 diabetes

Redondo, M. J., Evans-Molina, C., Steck, A. K., Atkinson, M. A. & Sosenko, J., Aug 1 2019, In : Diabetes care. 42, 8, p. 1357-1364 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

The integrated islet distribution program answers the call for improved human islet phenotyping and reporting of human islet characteristics in research articles

Brissova, M., Niland, J. C., Cravens, J., Olack, B., Sowinski, J. & Evans-Molina, C., Jan 1 2019, In : Diabetes. 68, 7, p. 1363-1365 3 p.

Research output: Contribution to journalLetter

Open Access
2 Scopus citations

The Integrated Islet Distribution Program answers the call for improved human islet phenotyping and reporting of human islet characteristics in research articles

Brissova, M., Niland, J. C., Cravens, J., Olack, B., Sowinski, J. & Evans-Molina, C., Jan 1 2019, In : Diabetologia.

Research output: Contribution to journalLetter

2 Scopus citations

The new medicare part D prescription drug benefit: An estimation of its effect on prescription drug costs in a medicare population with atrial fibrillation

Evans-Molina, C., Regan, S., Henault, L. E., Hylek, E. M. & Schwartz, G. R., Jul 1 2007, In : Journal of the American Geriatrics Society. 55, 7, p. 1038-1043 6 p.

Research output: Contribution to journalArticle

9 Scopus citations

The relationship between BMI and insulin resistance and progression from single to multiple autoantibody positivity and type 1 diabetes among TrialNet Pathway to Prevention participants

Meah, F. A., DiMeglio, L. A., Greenbaum, C. J., Blum, J. S., Sosenko, J. M., Pugliese, A., Geyer, S., Xu, P. & Evans-Molina, C., Jun 1 2016, In : Diabetologia. 59, 6, p. 1186-1195 10 p.

Research output: Contribution to journalArticle

16 Scopus citations

The risk of progression to type 1 diabetes is highly variable in individuals with multiple autoantibodies following screening

Jacobsen, L. M., Bocchino, L., Evans-Molina, C., DiMeglio, L., Goland, R., Wilson, D. M., Atkinson, M. A., Aye, T., Russell, W. E., Wentworth, J. M., Boulware, D., Geyer, S. & Sosenko, J. M., Mar 1 2020, In : Diabetologia. 63, 3, p. 588-596 9 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Role of Age and Excess Body Mass Index in Progression to Type 1 Diabetes in At-Risk Adults

Type 1 Diabetes TrialNet Study Group, Dec 1 2017, In : The Journal of clinical endocrinology and metabolism. 102, 12, p. 4596-4603 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
38 Scopus citations

The role of proteomics in assessing beta-cell dysfunction and death in type 1 diabetes

Nakayasu, E. S., Qian, W. J., Evans-Molina, C., Mirmira, R. G., Eizirik, D. L. & Metz, T. O., Jul 3 2019, In : Expert Review of Proteomics. 16, 7, p. 569-582 14 p.

Research output: Contribution to journalReview article

Thyroid hormone analogues for the treatment of metabolic disorders: New potential for unmet clinical needs?

Shoemaker, T. J., Kono, T., Mariash, C. N. & Evans-Molina, C., Nov 1 2012, In : Endocrine Practice. 18, 6, p. 954-964 11 p.

Research output: Contribution to journalReview article

27 Scopus citations

Translating the results of randomized trials into clinical practice: The challenge of warfarin candidacy among hospitalized elderly patients with atrial fibrillation

Hylek, E. M., D'Antonio, J., Evans-Molina, C., Shea, C., Henault, L. E. & Regan, S., Apr 1 2006, In : Stroke. 37, 4, p. 1075-1080 6 p.

Research output: Contribution to journalArticle

227 Scopus citations

Translational implications of the β-cell epigenome in diabetes mellitus

Johnson, J. S. & Evans-Molina, C., Jan 1 2015, In : Translational Research. 165, 1, p. 91-101 11 p.

Research output: Contribution to journalReview article

9 Scopus citations

Type 1 diabetes

DiMeglio, L. A., Evans-Molina, C. & Oram, R. A., Jun 16 2018, In : The Lancet. 391, 10138, p. 2449-2462 14 p.

Research output: Contribution to journalReview article

80 Scopus citations

Understanding PPAR-γ action - Just use your brain!

Evans-Molina, C., May 25 2011, In : Science translational medicine. 3, 84, 84ec77.

Research output: Contribution to journalComment/debate

1 Scopus citations
2 Scopus citations

β Cell dysfunction exists more than 5 years before type 1 diabetes diagnosis

Type 1 Diabetes TrialNet Study Group, Aug 9 2018, In : JCI Insight. 3, 15

Research output: Contribution to journalArticle

8 Scopus citations