Carmella Evans-Molina

  • 2433 Citations
  • 23 h-Index
20062019
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Publications 2006 2019

  • 2433 Citations
  • 23 h-Index
  • 81 Article
  • 7 Review article
  • 3 Letter
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Article
2006
1 Citation (Scopus)

Response to letter by Testa et al [2]

Hylek, E. M., Henault, L. E., Evans-Molina, C., Shea, C. & Regan, S., Dec 2006, In : Stroke. 37, 12, p. 2868 1 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Role of chromatin accessibility in the occupancy and transcription of the insulin gene by the pancreatic and duodenal homeobox factor 1

Francis, J., Babu, D. A., Deering, T. G., Chakrabarti, S. K., Garmey, J. C., Evans-Molina, C., Taylor, D. G. & Mirmira, R., Dec 2006, In : Molecular Endocrinology. 20, 12, p. 3133-3145 13 p.

Research output: Contribution to journalArticle

Chromatin
Insulin
Genes
Nucleosomes
DNA
224 Citations (Scopus)

Translating the results of randomized trials into clinical practice: The challenge of warfarin candidacy among hospitalized elderly patients with atrial fibrillation

Hylek, E. M., D'Antonio, J., Evans-Molina, C., Shea, C., Henault, L. E. & Regan, S., Apr 2006, In : Stroke. 37, 4, p. 1075-1080 6 p.

Research output: Contribution to journalArticle

Warfarin
Atrial Fibrillation
Randomized Controlled Trials
Stroke
Physicians
2007
48 Citations (Scopus)

Glucose regulation of insulin gene transcription and pre-mRNA processing in human islets

Evans-Molina, C., Garmey, J. C., Ketchum, R., Brayman, K. L., Deng, S. & Mirmira, R., Mar 2007, In : Diabetes. 56, 3, p. 827-835 9 p.

Research output: Contribution to journalArticle

RNA Precursors
Insulin
Glucose
Genes
Messenger RNA
803 Citations (Scopus)

Major hemorrhage and tolerability of warfarin in the first year of therapy among elderly patients with atrial fibrillation

Hylek, E. M., Evans-Molina, C., Shea, C., Henault, L. E. & Regan, S., May 2007, In : Circulation. 115, 21, p. 2689-2696 8 p.

Research output: Contribution to journalArticle

Warfarin
Atrial Fibrillation
Hemorrhage
Therapeutics
Stroke
9 Citations (Scopus)

The new medicare part D prescription drug benefit: An estimation of its effect on prescription drug costs in a medicare population with atrial fibrillation

Evans-Molina, C., Regan, S., Henault, L. E., Hylek, E. M. & Schwartz, G. R., Jul 2007, In : Journal of the American Geriatrics Society. 55, 7, p. 1038-1043 6 p.

Research output: Contribution to journalArticle

Medicare Part D
Drug Costs
Prescription Drugs
Medicare
Atrial Fibrillation
2009
12 Citations (Scopus)

Development of insulin-producing cells from primitive biologic precursors

Evans-Molina, C., Vestermark, G. L. & Mirmira, R., Feb 2009, In : Current Opinion in Organ Transplantation. 14, 1, p. 56-63 8 p.

Research output: Contribution to journalArticle

Insulin
Stem Cells
Multipotent Stem Cells
Pluripotent Stem Cells
Hormones
90 Citations (Scopus)

Peroxisome proliferator-activated receptor γ activation restores islet function in diabetic mice through reduction of endoplasmic reticulum stress and maintenance of euchromatin structure

Evans-Molina, C., Robbins, R. D., Kono, T., Tersey, S. A., Vestermark, G. L., Nunemaker, C. S., Garmey, J. C., Deering, T. G., Keller, S. R., Maier, B. & Mirmira, R., Apr 2009, In : Molecular and Cellular Biology. 29, 8, p. 2053-2067 15 p.

Research output: Contribution to journalArticle

Euchromatin
Peroxisome Proliferator-Activated Receptors
Endoplasmic Reticulum Stress
Maintenance
pioglitazone
2010
86 Citations (Scopus)

An intracellular role for ABCG1-mediated cholesterol transport in the regulated secretory pathway of mouse pancreatic β cells

Sturek, J. M., Castle, J. D., Trace, A. P., Page, L. C., Castle, A. M., Evans-Molina, C., Parks, J. S., Mirmira, R. & Hedrick, C. C., Jul 1 2010, In : Journal of Clinical Investigation. 120, 7, p. 2575-2589 15 p.

Research output: Contribution to journalArticle

ATP-Binding Cassette Transporters
Secretory Pathway
Cholesterol
Thiazolidinediones
Insulin
32 Citations (Scopus)

Liver X receptor agonists augment human islet function through activation of anaplerotic pathways and glycerolipid/free fatty acid cycling

Ogihara, T., Chuang, J. C., Vestermark, G. L., Garmey, J. C., Ketchum, R. J., Huang, X., Brayman, K. L., Thorner, M. O., Repa, J. J., Mirmira, R. & Evans-Molina, C., Feb 19 2010, In : Journal of Biological Chemistry. 285, 8, p. 5392-5404 13 p.

Research output: Contribution to journalArticle

Nonesterified Fatty Acids
Liver
Chemical activation
Insulin
Gene Expression
31 Citations (Scopus)
Peroxisome Proliferator-Activated Receptors
Type 2 Diabetes Mellitus
Cell Survival
Insulin
Insulin Resistance
2011
1 Citation (Scopus)

Adenosine and seizures - What's the big fat deal?

Evans-Molina, C., Jul 20 2011, In : Science Translational Medicine. 3, 92, 92ec113.

Research output: Contribution to journalArticle

Adenosine
Seizures
Fats

A hepatitis C mouse model that isn't chopped liver

Evans-Molina, C., Jun 22 2011, In : Science Translational Medicine. 3, 88, 88ec94.

Research output: Contribution to journalArticle

Hepatitis C
Liver

A snooze button for the biological clock

Evans-Molina, C., Aug 17 2011, In : Science Translational Medicine. 3, 96, 96ec131.

Research output: Contribution to journalArticle

Biological Clocks

A sweet spot for kallikrein in intracerebral hemorrhage

Evans-Molina, C., Mar 2 2011, In : Science Translational Medicine. 3, 72, 72ec27.

Research output: Contribution to journalArticle

Kallikreins
Cerebral Hemorrhage

A sweet success for diabetes research

Evans-Molina, C., Sep 21 2011, In : Science Translational Medicine. 3, 101, 101ec153.

Research output: Contribution to journalArticle

Research

Chronic pain. Epigenetic modulation of CNS pathways: What a pain!

Evans-Molina, C., Dec 7 2011, In : Science Translational Medicine. 3, 112, 112ec198.

Research output: Contribution to journalArticle

Epigenomics
Chronic Pain
Pain

Fetal DNA: A needle in the haystack

Evans-Molina, C., Mar 30 2011, In : Science Translational Medicine. 3, 76, 76ec43.

Research output: Contribution to journalArticle

Needles
DNA

Obesity. Yo-yo dieting: Biology or behavior?

Evans-Molina, C., Nov 9 2011, In : Science Translational Medicine. 3, 108, 108ec180.

Research output: Contribution to journalArticle

Obesity

Sperm find culture

Evans-Molina, C., Apr 27 2011, In : Science Translational Medicine. 3, 80, 80ec60.

Research output: Contribution to journalArticle

Spermatozoa

Spotlight on the silent lady killer

Evans-Molina, C., Oct 12 2011, In : Science Translational Medicine. 3, 104

Research output: Contribution to journalArticle

Understanding PPAR-γ action - Just use your brain!

Evans-Molina, C., May 25 2011, In : Science Translational Medicine. 3, 84, 84ec77.

Research output: Contribution to journalArticle

PPAR gamma
Brain
2012

A new FIX for hemophilia B

Evans-Molina, C., Jan 11 2012, In : Science Translational Medicine. 4, 116, 116ec5.

Research output: Contribution to journalArticle

Hemophilia B
167 Citations (Scopus)

Islet β-cell endoplasmic reticulum stress precedes the onset of type 1 diabetes in the nonobese diabetic mouse model

Tersey, S. A., Nishiki, Y., Templin, A. T., Cabrera, S. M., Stull, N. D., Colvin, S. C., Evans-Molina, C., Rickus, J. L., Maier, B. & Mirmira, R., Apr 2012, In : Diabetes. 61, 4, p. 818-827 10 p.

Research output: Contribution to journalArticle

Inbred NOD Mouse
Endoplasmic Reticulum Stress
Type 1 Diabetes Mellitus
Islets of Langerhans
Insulin
61 Citations (Scopus)

PPAR-γ activation restores pancreatic islet SERCA2 levels and prevents β-cell dysfunction under conditions of hyperglycemic and cytokine stress

Kono, T., Ahn, G., Moss, D. R., Gann, L., Zarain-Herzberg, A., Nishiki, Y., Fueger, P. T., Ogihara, T. & Evans-Molina, C., Feb 1 2012, In : Molecular Endocrinology. 26, 2, p. 257-271 15 p.

Research output: Contribution to journalArticle

pioglitazone
Peroxisome Proliferator-Activated Receptors
Islets of Langerhans
Cytokines
Cyclin-Dependent Kinase 5
27 Citations (Scopus)

Thyroid hormone analogues for the treatment of metabolic disorders: New potential for unmet clinical needs?

Shoemaker, T. J., Kono, T., Mariash, C. N. & Evans-Molina, C., Nov 1 2012, In : Endocrine Practice. 18, 6, p. 954-964 11 p.

Research output: Contribution to journalArticle

Thyroid Hormone Receptors
Thyroid Hormones
Hormones
Type 2 Diabetes Mellitus
Obesity
2013

Achieving "PeaK-A" insulin secretion

Evans-Molina, C. & Mirmira, R., May 2013, In : Diabetes. 62, 5, p. 1389-1390 2 p.

Research output: Contribution to journalArticle

Insulin-Secreting Cells
Second Messenger Systems
Cyclic AMP-Dependent Protein Kinases
Hyperglycemia
Cyclic AMP
19 Citations (Scopus)

Divergent compensatory responses to high-fat diet between C57Bl6/J and c57BlKS/J inbred mouse strains

Sims, E. K., Hatanaka, M., Morris, D. L., Tersey, S. A., Kono, T., Chaudry, Z. Z., Day, K. H., Moss, D. R., Stull, N. D., Mirmira, R. & Evans-Molina, C., Dec 15 2013, In : American Journal of Physiology - Endocrinology and Metabolism. 305, 12

Research output: Contribution to journalArticle

Inbred Strains Mice
High Fat Diet
Glucose Intolerance
Intra-Abdominal Fat
pioglitazone
58 Citations (Scopus)

High glucose represses β-klotho expression and impairs fibroblast growth factor 21 action in mouse pancreatic islets: Involvement of peroxisome proliferator-activated receptor γ signaling

So, W. Y., Cheng, Q., Chen, L., Evans-Molina, C., Xu, A., Lam, K. S. L. & Leung, P. S., Nov 2013, In : Diabetes. 62, 11, p. 3751-3759 9 p.

Research output: Contribution to journalArticle

Peroxisome Proliferator-Activated Receptors
Islets of Langerhans
Glucose
rosiglitazone
Hyperglycemia
24 Citations (Scopus)

Lost in translation: Endoplasmic reticulum stress and the decline of β-cell health in diabetes mellitus

Evans-Molina, C., Hatanaka, M. & Mirmira, R., Sep 2013, In : Diabetes, Obesity and Metabolism. 15, S3, p. 159-169 11 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Diabetes Mellitus
Health
Type 1 Diabetes Mellitus
Type 2 Diabetes Mellitus
23 Citations (Scopus)

Streptozotocin is equally diabetogenic whether administered to fed or fasted mice

Chaudhry, Z. Z., Morris, D. L., Moss, D. R., Sims, E. K., Chiong, Y., Kono, T. & Evans-Molina, C., 2013, In : Laboratory Animals. 47, 4, p. 257-265 9 p.

Research output: Contribution to journalArticle

streptozotocin
Streptozocin
mice
fasting
Fasting
2014
6 Citations (Scopus)

A case of calciphylaxis in a patient with hypoparathyroidism and normal renal function

Erdel, B. L., Juneja, R. & Evans-Molina, C., Jun 1 2014, In : Endocrine Practice. 20, 6

Research output: Contribution to journalArticle

Calciphylaxis
Hypoparathyroidism
Calcitriol
Kidney
Calcium
31 Citations (Scopus)

Bisphenol A, obesity, and type 2 diabetes mellitus: Genuine concern or unnecessary preoccupation?

Mirmira, P. & Evans-Molina, C., 2014, In : Translational Research. 164, 1, p. 13-21 9 p.

Research output: Contribution to journalArticle

Medical problems
Type 2 Diabetes Mellitus
Obesity
Food storage
Food Storage
35 Citations (Scopus)

Established and emerging biomarkers for the prediction of type 1 diabetes: A systematic review

Watkins, R. A., Evans-Molina, C., Blum, J. & DiMeglio, L., 2014, In : Translational Research. 164, 2, p. 110-121 12 p.

Research output: Contribution to journalArticle

Biomarkers
Medical problems
Type 1 Diabetes Mellitus
Autoantibodies
Autoimmune Diseases
18 Citations (Scopus)

From immunobiology to β-cell biology: The changing perspective on type 1 diabetes

Maganti, A., Evans-Molina, C. & Mirmira, R., 2014, In : Islets. 6, 2, p. e28778-1-e28778-5 e28778.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
Cell Biology
Autoimmunity
Inbred NOD Mouse
Protein Folding
34 Citations (Scopus)

Human adipose-derived stromal/stem cells protect against STZ-induced hyperglycemia: Analysis of hASC-derived paracrine effectors

Kono, T., Sims, E. K., Moss, D. R., Yamamoto, W., Ahn, G., Diamond, J., Tong, X., Day, K. H., Territo, P., Hanenberg, H., Traktuev, D., March, K. L. & Evans-Molina, C., 2014, In : Stem Cells. 32, 7, p. 1831-1842 12 p.

Research output: Contribution to journalArticle

Tissue Inhibitor of Metalloproteinase-1
Stromal Cells
Hyperglycemia
Stem Cells
Type 1 Diabetes Mellitus
25 Citations (Scopus)

Palmitate induces mRNA translation and increases ER protein load in islet ß-cells via activation of the mammalian target of rapamycin pathway

Hatanaka, M., Maier, B., Sims, E. K., Templin, A. T., Kulkarni, R. N., Evans-Molina, C. & Mirmira, R., Oct 1 2014, In : Diabetes. 63, 10, p. 3404-3415 12 p.

Research output: Contribution to journalArticle

Palmitates
Protein Biosynthesis
Sirolimus
Islets of Langerhans
Unfolded Protein Response
20 Citations (Scopus)

Pancreatic and duodenal homeobox protein 1 (Pdx-1) maintains endoplasmic reticulum calcium levels through transcriptional regulation of sarco-endoplasmic reticulum calcium ATPase 2b (SERCA2b) in the islet β cell

Johnson, J. S., Kono, T., Tong, X., Yamamoto, W. R., Zarain-Herzberg, A., Merrins, M. J., Satin, L. S., Gilon, P. & Evans-Molina, C., Nov 21 2014, In : Journal of Biological Chemistry. 289, 47, p. 32798-32810 13 p.

Research output: Contribution to journalArticle

Calcium-Transporting ATPases
Homeobox Genes
Islets of Langerhans
Endoplasmic Reticulum
Calcium
40 Citations (Scopus)

Regenerative therapeutic potential of adipose stromal cells in early stage diabetic retinopathy

Rajashekhar, G., Ramadan, A., Abburi, C., Callaghan, B., Traktuev, D., Evans-Molina, C., Maturi, R., Harris, A., Kern, T. S. & March, K. L., Jan 9 2014, In : PLoS One. 9, 1, e84671.

Research output: Contribution to journalArticle

diabetic retinopathy
stromal cells
Diabetic Retinopathy
Stromal Cells
eyes
5 Citations (Scopus)

Shock wave lithotripsy targeting of the kidney and pancreas does not increase the severity of metabolic syndrome in a porcine model

Handa, R., Evan, A., Connors, B. A., Johnson, C. D., Liu, Z., Alloosh, M., Sturek, M., Evans-Molina, C., Mandeville, J. A., Gnessin, E. & Lingeman, J. E., Oct 1 2014, In : Journal of Urology. 192, 4, p. 1257-1265 9 p.

Research output: Contribution to journalArticle

Lithotripsy
Pancreas
Swine
Kidney
Glucose
2 Citations (Scopus)
Biomarkers
Medical problems
Proteomics
2015
45 Citations (Scopus)

Elevations in circulating methylated and unmethylated preproinsulin DNA in new-onset type 1 diabetes

Fisher, M. M., Watkins, R. A., Blum, J., Evans-Molina, C., Chalasani, N., DiMeglio, L., Mather, K., Tersey, S. A. & Mirmira, R., Nov 1 2015, In : Diabetes. 64, 11, p. 3867-3872 6 p.

Research output: Contribution to journalArticle

Type 1 Diabetes Mellitus
DNA
preproinsulin
Autoimmune Hepatitis
Type 2 Diabetes Mellitus
3 Citations (Scopus)

Fetal hyperglycemia and a high-fat diet contribute to aberrant glucose tolerance and hematopoiesis in adult rats

Blue, E. K., Ballman, K., Boyle, F., Oh, E., Kono, T., Quinney, S., Thurmond, D. C., Evans-Molina, C. & Haneline, L., Feb 11 2015, In : Pediatric Research. 77, 2, p. 316-325 10 p.

Research output: Contribution to journalArticle

Hematopoiesis
High Fat Diet
Hyperglycemia
Mothers
Glucose
29 Citations (Scopus)

Leukotriene B4-mediated sterile inflammation promotes susceptibility to sepsis in a mouse model of type 1 diabetes

Filgueiras, L. R., Brandt, S. L., Wang, S., Wang, Z., Morris, D. L., Evans-Molina, C., Mirmira, R., Jancar, S. & Serezani, C. H., Jan 27 2015, In : Science Signaling. 8, 361, p. ra10

Research output: Contribution to journalArticle

Leukotriene B4
Medical problems
Type 1 Diabetes Mellitus
Sepsis
Inflammation
13 Citations (Scopus)
Reticulum
AMP-Activated Protein Kinases
Calcium-Transporting ATPases
Protein Stability
Nitric Oxide
13 Citations (Scopus)

SET7/9 enzyme regulates cytokine-induced expression of inducible nitric-oxide synthase through methylation of Lysine 4 at histone 3 in the islet β cell

Fujimaki, K., Ogihara, T., Morris, D. L., Oda, H., Iida, H., Fujitani, Y., Mirmira, R., Evans-Molina, C. & Watada, H., Jul 3 2015, In : Journal of Biological Chemistry. 290, 27, p. 16607-16618 12 p.

Research output: Contribution to journalArticle

Methylation
Nitric Oxide Synthase Type II
Islets of Langerhans
Histones
Lysine
9 Citations (Scopus)

Translational implications of the β-cell epigenome in diabetes mellitus

Johnson, J. S. & Evans-Molina, C., Jan 1 2015, In : Translational Research. 165, 1, p. 91-101 11 p.

Research output: Contribution to journalArticle

Medical problems
Diabetes Mellitus
DNA
Transcription
Chromatin
2016
2 Citations (Scopus)

A case of extragastrointestinal stromal tumor complicated by severe hypoglycemia: A unique presentation of a rare tumor

Saeed, Z., Taleb, S. & Evans-Molina, C., Dec 1 2016, In : BMC Cancer. 16, 1, 930.

Research output: Contribution to journalArticle

Hypoglycemia
Insulin-Like Growth Factor II
Neoplasms
Insulin-Like Growth Factor I
Insulin
14 Citations (Scopus)

CD40 promotes mhc class II expression on adipose tissue macrophages and regulates adipose tissue CD4+ T cells with obesity

Morris, D. L., Oatmen, K. E., Mergian, T. A., Cho, K. W., Delproposto, J. L., Singer, K., Evans-Molina, C., O’Rourke, R. W. & Lumeng, C. N., Jun 1 2016, In : Journal of Leukocyte Biology. 99, 6, p. 1107-1119 13 p.

Research output: Contribution to journalArticle

Adipose Tissue
Obesity
Macrophages
T-Lymphocytes
CD40 Ligand