Chadi Hage

  • 2993 Citations
  • 31 h-Index
20022019
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Publications 2002 2019

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2002
4 Citations (Scopus)

Evaluation of Tc-99m tetrofosmin scan for coronary artery disease diagnosis

Chammas, E., Yatim, A., Hage, C., Sokhn, K., Tarcha, W. & Ghanem, G., Sep 2002, In : Asian Cardiovascular and Thoracic Annals. 10, 3, p. 244-247 4 p.

Research output: Contribution to journalArticle

Exercise Test
Coronary Artery Disease
Arteries
Myocardial Perfusion Imaging
Coronary Angiography
26 Citations (Scopus)

Mucosal and invasive fungal infections in HIV/AIDS.

Hage, C., Goldman, M. & Wheat, L. J., May 31 2002, In : European Journal of Medical Research. 7, 5, p. 236-241 6 p.

Research output: Contribution to journalArticle

Acquired Immunodeficiency Syndrome
HIV
Mycoses
Therapeutics
Immune Reconstitution Inflammatory Syndrome
2003
186 Citations (Scopus)

Histoplasmosis after treatment with anti-tumor necrosis factor-α therapy

Wood, K. L., Hage, C., Knox, K. S., Kleiman, M. B., Sannuti, A., Day, R. B., Wheat, L. J. & Twigg, H., May 1 2003, In : American Journal of Respiratory and Critical Care Medicine. 167, 9, p. 1279-1282 4 p.

Research output: Contribution to journalArticle

Histoplasmosis
Histoplasma
Alveolar Macrophages
Tumor Necrosis Factor-alpha
Monocytes
13 Citations (Scopus)

Pleural Mesothelial Cell (PMC) Defense Mechanisms Against Malignancy

Nasreen, N., Mohammed, K. A., Sanders, K., Hardwick, J., Van Horn, R. D., Sriram, P. S., Ramirez-Icaza, C., Hage, C. & Antony, V. B., 2003, In : Oncology Research. 14, 3, p. 155-161 7 p.

Research output: Contribution to journalArticle

Endostatins
Neoplasms
Ovarian Neoplasms
Pleura
Heart Failure
88 Citations (Scopus)

Pulmonary Cryptococcosis after Initiation of Anti-Tumor Necrosis Factor-α Therapy

Hage, C., Wood, K. L., Winer-Muram, H. T., Wilson, S. J., Sarosi, G. & Knox, K. S., Dec 2003, In : Chest. 124, 6, p. 2395-2397 3 p.

Research output: Contribution to journalArticle

Cryptococcosis
Tumor Necrosis Factor-alpha
Lung
Mycoses
Therapeutics
2004
3 Citations (Scopus)

Macrophages exposed to lymphotropic and monocytotropic HIV induce similar CTL responses despite differences in productive infection

Knox, K. S., Day, R. B., Wood, K. L., Kohli, L. L., Hage, C., Foresman, B. H., Schnizlein-Bick, C. T. & Twigg, H., Jun 2004, In : Cellular Immunology. 229, 2, p. 130-138 9 p.

Research output: Contribution to journalArticle

Cytotoxic T-Lymphocytes
Macrophages
HIV
Infection
HIV Infections
20 Citations (Scopus)

Pathogenesis of pleural infection

Hage, C., Mohammed, K. A. & Antony, V. B., Mar 2004, In : Respirology. 9, 1, p. 12-15 4 p.

Research output: Contribution to journalArticle

Pleura
Innate Immunity
Adaptive Immunity
Infection
Viscera
2005
27 Citations (Scopus)

Human immunodeficiency virus gp120 downregulates CD1d cell surface expression

Hage, C., Kohli, L. L., Cho, S., Brutkiewicz, R., Twigg, H. & Knox, K. S., Apr 15 2005, In : Immunology Letters. 98, 1, p. 131-135 5 p.

Research output: Contribution to journalArticle

Down-Regulation
HIV
HIV Infections
HIV Envelope Protein gp120
Highly Active Antiretroviral Therapy
3 Citations (Scopus)

Infliximab does not affect dendritic cells' mediated lymphoproliferative response to Histoplasma capsulatum [3] (multiple letters)

Hage, C., Wheat, L. J., Twigg, H., Knox, K. S. & Deepe, G. S., Dec 1 2005, In : Clinical Infectious Diseases. 41, 11, p. 1685-1687 3 p.

Research output: Contribution to journalArticle

Histoplasma
Dendritic Cells
Cultured Cells
Monoclonal Antibodies
Cell Proliferation
2006
15 Citations (Scopus)

Cytometric analysis of BAL T cells labeled with a standardized antibody cocktail correlates with immunohistochemical staining

Smith, P. A., Kohli, L. M., Wood, K. L., Hage, C., Twigg, H. & Knox, K. S., May 2006, In : Cytometry Part B - Clinical Cytometry. 70, 3, p. 170-178 9 p.

Research output: Contribution to journalArticle

Bronchoalveolar Lavage
Staining and Labeling
T-Lymphocytes
Antibodies
CD4-CD8 Ratio
3 Citations (Scopus)

Functional impairment of CD4 T cells despite normalization of T cell number in HIV

Knox, K. S., Day, R. B., Kohli, L. M., Hage, C. & Twigg, H., Jul 2006, In : Cellular Immunology. 242, 1, p. 46-51 6 p.

Research output: Contribution to journalArticle

Cell Count
HIV
T-Lymphocytes
CD4 Lymphocyte Count
Histocompatibility Antigens Class II
2007

A 30-year-old man with HIV infection and fever with cough 2 months after starting antiretroviral therapy

Xhani, D., Hage, C. & Knox, K. S., Jul 2007, In : Chest. 132, 1, p. 354-357 4 p.

Research output: Contribution to journalArticle

Cough
HIV Infections
Fever
Therapeutics
43 Citations (Scopus)

Diagnosis of pulmonary histoplasmosis and blastomycosis by detection of antigen in bronchoalveolar lavage fluid using an improved second-generation enzyme-linked immunoassay

Hage, C., Davis, T., Egan, L., Parker, M., Fuller, D., LeMonte, A. M., Durkin, M., Connelly, P., Joseph Wheat, L., Blue-Hnidy, D. & Knox, K. S., Jan 2007, In : Respiratory Medicine. 101, 1, p. 43-47 5 p.

Research output: Contribution to journalArticle

Blastomycosis
Histoplasmosis
Bronchoalveolar Lavage Fluid
Immunoenzyme Techniques
Antigens
106 Citations (Scopus)

Histoplasmosis-associated cross-reactivity in the biorad platelia Aspergillus enzyme immunoassay

Wheat, L. J., Hackett, E., Durkin, M., Connolly, P., Petraitiene, R., Walsh, T. J., Knox, K. & Hage, C., May 2007, In : Clinical and Vaccine Immunology. 14, 5, p. 638-640 3 p.

Research output: Contribution to journalArticle

Histoplasmosis
Aspergillus
Immunoenzyme Techniques
Enzymes
Histoplasma
56 Citations (Scopus)

Plasmalyte as a cause of false-positive results for Aspergillus galactomannan in bronchoalveolar lavage fluid [2]

Hage, C., Reynolds, J. M., Durkin, M., Wheat, L. J. & Knox, K. S., Feb 2007, In : Journal of Clinical Microbiology. 45, 2, p. 676-677 2 p.

Research output: Contribution to journalArticle

Fungal Antigens
Plasma Substitutes
False Positive Reactions
Mannans
Aspergillosis
2008

A 24-year-old man with mediastinal mass, dyspnea, and a pleural effusion

Rose, A. S., Knox, K. S. & Hage, C., Jul 2008, In : Chest. 134, 1, p. 200-203 4 p.

Research output: Contribution to journalArticle

Pleural Effusion
Dyspnea
6 Citations (Scopus)

An 81-year-old man with lactic acidosis, refractory hypoglycemia, and lymphocytosis

Diab, K., Knox, K. S. & Hage, C., Jan 2008, In : Chest. 133, 1, p. 306-310 5 p.

Research output: Contribution to journalArticle

Lymphocytosis
Lactic Acidosis
Hypoglycemia
31 Citations (Scopus)

Corticosteroids for blastomycosis-induced ARDS: A report of two patients and review of the literature

Lahm, T., Neese, S., Thomburg, A. T., Ober, M. D., Sarosi, G. A. & Hage, C., Jun 2008, In : Chest. 133, 6, p. 1478-1480 3 p.

Research output: Contribution to journalArticle

Blastomycosis
Adrenal Cortex Hormones
Amphotericin B
Blastomyces
Histoplasma
13 Citations (Scopus)

Cryptococcal glucoxylomannan does not exhibit cross-reactivity in the MVista Histoplasma antigen enzyme immunoassay

Zhuang, D., Hage, C., Jesus, M. D., Hackett, E., Durkin, M., Davis, T., Casadevall, A. & Wheat, L. J., Feb 2008, In : Clinical and Vaccine Immunology. 15, 2, p. 392-393 2 p.

Research output: Contribution to journalArticle

Histoplasma
Immunoenzyme Techniques
Antigens
Enzymes
Cryptococcus neoformans
14 Citations (Scopus)

Detection of Histoplasma capsulatum antigenuria by ultrafiltration of samples with false-negative results

Egan, L., Connolly, P. A., Fuller, D., Davis, T., Witt, J., Knox, K. S., Hage, C. & Wheat, L. J., Apr 2008, In : Clinical and Vaccine Immunology. 15, 4, p. 726-728 3 p.

Research output: Contribution to journalArticle

Histoplasma
Ultrafiltration
Antigens
Histoplasmosis
Limit of Detection
443 Citations (Scopus)

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

Brenchley, J. M., Paiardini, M., Knox, K. S., Asher, A. I., Cervasi, B., Asher, T. E., Scheinberg, P., Price, D. A., Hage, C., Kholi, L. M., Khoruts, A., Frank, I., Else, J., Schacker, T., Silvestri, G. & Douek, D. C., Oct 1 2008, In : Blood. 112, 7, p. 2826-2835 10 p.

Research output: Contribution to journalArticle

Th17 Cells
T-cells
Blood
Cercocebus atys
T-Lymphocytes
58 Citations (Scopus)

High frequencies of polyfunctional HIV-specific T cells are associated with preservation of mucosal CD4 T cells in bronchoalveolar lavage

Brenchley, J. M., Knox, K. S., Asher, A. I., Price, D. A., Kohli, L. M., Gostick, E., Hill, B. J., Hage, C., Brahmi, Z., Khoruts, A., Twigg, H., Schacker, T. W. & Douek, D. C., Jan 2008, In : Mucosal Immunology. 1, 1, p. 49-58 10 p.

Research output: Contribution to journalArticle

Bronchoalveolar Lavage
HIV
T-Lymphocytes
Virus Diseases
Gastrointestinal Tract
19 Citations (Scopus)

Histoplasmosis as a cause for a positive Fungitell™ (I → 3)-β-D-glucan test

Egan, L., Connolly, P., Wheat, L. J., Fuller, D., Davis, T., Knox, K. S. & Hage, C., Feb 2008, In : Medical Mycology. 46, 1, p. 93-95 3 p.

Research output: Contribution to journalArticle

histoplasmosis
Histoplasmosis
glucans
testing
Glucans
1 Citation (Scopus)

Lung primary primitive neuroectodermal tumor in an adult patient

Najm, S., Vakili, S. T., Singh, R. S., Hammoud, Z., Knox, K. S. & Hage, C., 2008, In : Respiratory Medicine CME. 1, 2, p. 161-163 3 p.

Research output: Contribution to journalArticle

Primitive Neuroectodermal Tumors
Sarcoma
Lung Neoplasms
Lung
75 Citations (Scopus)

Performance characteristics of the platelia Aspergillus enzyme immunoassay for detection of Aspergillus galactomannan antigen in bronchoalveolar lavage fluid

Husain, S., Clancy, C. J., Nguyen, M. H., Swartzentruber, S., Leather, H., LeMonte, A. M., Durkin, M. M., Knox, K. S., Hage, C., Bentsen, C., Singh, N., Wingard, J. R. & Wheat, L. J., Dec 2008, In : Clinical and Vaccine Immunology. 15, 12, p. 1760-1763 4 p.

Research output: Contribution to journalArticle

Transplants
Aspergillus
Bronchoalveolar Lavage Fluid
Immunoenzyme Techniques
Bronchoalveolar Lavage
38 Citations (Scopus)

Pulmonary histoplasmosis

Hage, C., Wheat, L. J., Loyd, J., Allen, S. D., Blue, D. & Knox, K. S., Apr 2008, In : Seminars in Respiratory and Critical Care Medicine. 29, 2, p. 151-165 15 p.

Research output: Contribution to journalArticle

Histoplasmosis
Antigens
Lung
Bronchoalveolar Lavage Fluid
Guidelines
2009

Acute respiratory failure and diffuse pulmonary infiltrates four weeks after rituximab therapy

Hatoum, H. H., Sarosi, G. A., Knox, K. S. & Hage, C. A., 2009, In : Respiratory Medicine CME. 2, 3, p. 134-136 3 p.

Research output: Contribution to journalArticle

Prednisone
Respiratory Insufficiency
Pneumocystis
Lung
Pneumocystis Pneumonia
1 Citation (Scopus)

Broncholithiasis causing acute respiratory failure: Successfully treated by flexible bronchoscopy

Melendez, A. G., Hosein, M., Sheski, F., Knox, K. S. & Hage, C., 2009, In : Respiratory Medicine CME. 2, 1, p. 27-30 4 p.

Research output: Contribution to journalArticle

Bronchoscopy
Respiratory Insufficiency
36 Citations (Scopus)

Improved detection of Histoplasma antigenemia following dissociation of immune complexes

Swartzentruber, S., LeMonte, A., Witt, J., Fuller, D., Davis, T., Hage, C., Connolly, P., Durkin, M. & Wheat, L. J., Mar 2009, In : Clinical and Vaccine Immunology. 16, 3, p. 320-322 3 p.

Research output: Contribution to journalArticle

Histoplasma
Antigen-Antibody Complex
Edetic Acid
Histoplasmosis
Hot Temperature
22 Citations (Scopus)

Invasive Fungal Infections in the Era of Biologics

Arnold, T. M., Sears, C. & Hage, C., Jun 2009, In : Clinics in Chest Medicine. 30, 2, p. 279-286 8 p.

Research output: Contribution to journalArticle

Mycoses
Biological Products
Tumor Necrosis Factor-alpha
Infection
Biological Factors
21 Citations (Scopus)

Surgical Management of Pulmonary and Mediastinal Sequelae of Histoplasmosis: A Challenging Spectrum

Hammoud, Z. T., Rose, A. S., Hage, C., Knox, K. S., Rieger, K. & Kesler, K., Aug 2009, In : Annals of Thoracic Surgery. 88, 2, p. 399-403 5 p.

Research output: Contribution to journalArticle

Histoplasmosis
Lung
Thorax
Superior Vena Cava Syndrome
Hemoptysis
2010

51 year-old male with dyspnea and hypoxia

Sears, C., Bosslet, G. & Hage, C., 2010, In : Respiratory Medicine CME. 3, 3, p. 135-137 3 p.

Research output: Contribution to journalArticle

Atrial Heart Septal Defects
Dyspnea
Obstructive Sleep Apnea
Pulmonary Hypertension
Heart Diseases
28 Citations (Scopus)

Aspergillus infections in the critically ill

Dutkiewicz, R. & Hage, C., May 15 2010, In : Proceedings of the American Thoracic Society. 7, 3, p. 204-209 6 p.

Research output: Contribution to journalArticle

Aspergillosis
Aspergillus
Critical Illness
Infection
Hematologic Neoplasms
33 Citations (Scopus)

Blastomycosis in Indiana: Digging up more cases

Carlos, W., Rose, A. S., Wheat, L. J., Norris, S., Sarosi, G. A., Knox, K. S. & Hage, C., Dec 1 2010, In : Chest. 138, 6, p. 1377-1382 6 p.

Research output: Contribution to journalArticle

Blastomycosis
Fungal Antigens
Histoplasmosis
Disease Outbreaks
Comorbidity
59 Citations (Scopus)

Diagnosis of histoplasmosis by antigen detection in BAL fluid

Hage, C., Davis, T., Fuller, D., Egan, L., Witt, J. R., Wheat, L. J. & Knox, K. S., Mar 1 2010, In : Chest. 137, 3, p. 623-628 6 p.

Research output: Contribution to journalArticle

Dimercaprol
Histoplasmosis
Antigens
Blastomycosis
Histoplasma
11 Citations (Scopus)

Editorial: Diagnosis of pulmonary histoplasmosis using antigen detection in the bronchoalveolar lavage

Hage, C. & Wheat, L. J., Aug 2010, In : Expert Review of Respiratory Medicine. 4, 4, p. 427-429 3 p.

Research output: Contribution to journalArticle

Fungal Lung Diseases
Fungal Antigens
Blastomycosis
Predictive Value of Tests
Coccidioidomycosis
61 Citations (Scopus)

Histoplasmosis

Knox, K. S. & Hage, C., May 15 2010, In : Proceedings of the American Thoracic Society. 7, 3, p. 169-172 4 p.

Research output: Contribution to journalArticle

Histoplasmosis
Mycoses
North America
Therapeutics
Lung
9 Citations (Scopus)

Histoplasmosis in solid organ transplant recipients

Hage, C., Kleiman, M. B. & Wheat, L. J., Jan 2010, In : Clinical Infectious Diseases. 50, 1, p. 122-123 2 p.

Research output: Contribution to journalArticle

Histoplasmosis
Organ Transplantation
Transplants
Transplant Recipients
94 Citations (Scopus)

Recognition, diagnosis, and treatment of histoplasmosis complicating tumor necrosis factor blocker therapy

Hage, C., Bowyer, S., Tarvin, S. E., Helper, D., Kleiman, M. B. & Wheat, L. J., Jan 2010, In : Clinical Infectious Diseases. 50, 1, p. 85-92 8 p.

Research output: Contribution to journalArticle

Histoplasmosis
Tumor Necrosis Factor-alpha
Immune Reconstitution Inflammatory Syndrome
Opportunistic Infections
Bronchoalveolar Lavage
20 Citations (Scopus)

Reconstitution of CD4 T cells in bronchoalveolar lavage fluid after initiation of highly active antiretroviral therapy

Knox, K. S., Vinton, C., Hage, C., Kohli, L. M., Twigg, H., Klatt, N. R., Zwickl, B., Waltz, J., Goldman, M., Douek, D. C. & Brenchley, J. M., 2010, In : Journal of Virology. 84, 18, p. 9010-9018 9 p.

Research output: Contribution to journalArticle

Highly Active Antiretroviral Therapy
Bronchoalveolar Lavage Fluid
T-lymphocytes
T-Lymphocytes
therapeutics
19 Citations (Scopus)

Traditional and emerging antifungal therapies

Arnold, T. M., Dotson, E., Sarosi, G. A. & Hage, C., May 15 2010, In : Proceedings of the American Thoracic Society. 7, 3, p. 222-228 7 p.

Research output: Contribution to journalArticle

Antifungal Agents
Echinocandins
Triazoles
Drug-Related Side Effects and Adverse Reactions
Drug Interactions
2011
167 Citations (Scopus)

A multicenter evaluation of tests for diagnosis of histoplasmosis

Hage, C., Ribes, J. A., Wengenack, N. L., Baddour, L. M., Assi, M., McKinsey, D. S., Hammoud, K., Alapat, D., Esther Babady, N., Parker, M., Fuller, D., Noor, A., Davis, T., Rodgers, M., Connolly, P. A., El Haddad, B. & Joseph Wheat, L., Sep 1 2011, In : Clinical Infectious Diseases. 53, 5, p. 448-454 7 p.

Research output: Contribution to journalArticle

Histoplasmosis
Blastomycosis
Antigens
Histoplasma
Immunocompromised Host
290 Citations (Scopus)

An official American Thoracic Society statement: Treatment of fungal infections in adult pulmonary and critical care patients

Limper, A. H., Knox, K. S., Sarosi, G. A., Ampel, N. M., Bennett, J. E., Catanzaro, A., Davies, S. F., Dismukes, W. E., Hage, C., Marr, K. A., Mody, C. H., Perfect, J. R. & Stevens, D. A., Jan 1 2011, In : American Journal of Respiratory and Critical Care Medicine. 183, 1, p. 96-128 33 p.

Research output: Contribution to journalArticle

Mycoses
Critical Care
Lung
Fungal Lung Diseases
Azoles
36 Citations (Scopus)

Antigen detection in bronchoalveolar lavage fluid for diagnosis of fungal pneumonia

Hage, C., Knox, K. S., Davis, T. & Wheat, L. J., May 2011, In : Current Opinion in Pulmonary Medicine. 17, 3, p. 167-171 5 p.

Research output: Contribution to journalArticle

Bronchoalveolar Lavage Fluid
Pneumonia
Bronchoalveolar Lavage
Antigens
Aspergillosis
4 Citations (Scopus)

Defective nitric oxide production by alveolar macrophages during Pneumocystis pneumonia

Lasbury, M. E., Liao, C. P., Hage, C., Durant, P. J., Tschang, D., Wang, S. H., Zhang, C. & Lee, C-H., Apr 1 2011, In : American Journal of Respiratory Cell and Molecular Biology. 44, 4, p. 540-547 8 p.

Research output: Contribution to journalArticle

Pneumocystis Pneumonia
Alveolar Macrophages
Nitric Oxide
Nitric Oxide Synthase Type II
Pneumocystis
38 Citations (Scopus)

Detection of Blastomyces dermatitidis antigen in patients with newly diagnosed blastomycosis

Bariola, J. R., Hage, C., Durkin, M., Bensadoun, E., Gubbins, P. O., Wheat, L. J. & Bradsher, R. W., Feb 2011, In : Diagnostic Microbiology and Infectious Disease. 69, 2, p. 187-191 5 p.

Research output: Contribution to journalArticle

Blastomyces
Blastomycosis
Antigens
Edetic Acid
Histoplasmosis
28 Citations (Scopus)

Histoplasma antigen clearance during treatment of histoplasmosis in patients with AIDS determined by a quantitative antigen enzyme immunoassay

Hage, C., Kirsch, E. J., Stump, T. E., Kauffman, C. A., Goldman, M., Connolly, P., Johnson, P. C., Wheat, L. J. & Baddley, J. W., Apr 2011, In : Clinical and Vaccine Immunology. 18, 4, p. 661-666 6 p.

Research output: Contribution to journalArticle

Histoplasma
Histoplasmosis
Immunoenzyme Techniques
Acquired Immunodeficiency Syndrome
Antigens
13 Citations (Scopus)

Investigation of the efficacy of micafungin in the treatment of histoplasmosis using two North American strains of Histoplasma capsulatum

Hage, C., Connolly, P., Horan, D., Durkin, M., Smedema, M., Zarnowski, R., Smith, P. & Wheat, L. J., Sep 2011, In : Antimicrobial Agents and Chemotherapy. 55, 9, p. 4447-4450 4 p.

Research output: Contribution to journalArticle

Histoplasma
Histoplasmosis
Fungi
Yeasts
micafungin
45 Citations (Scopus)

The human metapneumovirus: A case series and review of the literature

Shahda, S., Carlos, W., Kiel, P. J., Khan, B. & Hage, C., Jun 2011, In : Transplant Infectious Disease. 13, 3, p. 324-328 5 p.

Research output: Contribution to journalArticle

Metapneumovirus
Immunocompromised Host
Ribavirin
Intravenous Immunoglobulins
Respiratory Syncytial Viruses
2012
1 Citation (Scopus)
Cryptococcus
Clinical Laboratory Techniques
Fungi
Fungal Antigens
Serology