Clark Wells

  • 1571 Citations
  • 22 h-Index
19972019
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Rho Guanine Nucleotide Exchange Factors Chemical Compounds
Proteins Medicine & Life Sciences
GTP-Binding Protein Regulators Chemical Compounds
Glycogen Medicine & Life Sciences
Starch Medicine & Life Sciences
14-3-3 Proteins Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Membranes Chemical Compounds

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NIH Grants 2011 2016

Breast
Cell Proliferation
Breast Neoplasms
Growth
Triple Negative Breast Neoplasms

Publications 1997 2019

  • 1571 Citations
  • 22 h-Index
  • 32 Article

Identification of specific lysines and arginines that mediate angiomotin membrane association

Hall, LC., Donovan, E., Araya, M., Idowa, E., Jiminez-Segovia, I., Folck, A., Wells, C. & Kimble-Hill, A. C., Apr 12 2019, In : ACS Omega. 4, 4, p. 6726-6736 11 p.

Research output: Contribution to journalArticle

Open Access
Arginine
Lysine
Proteins
Membranes
Lipids
2 Citations (Scopus)

Small-Molecule Covalent Modification of Conserved Cysteine Leads to Allosteric Inhibition of the TEAD⋅Yap Protein-Protein Interaction

Bum-Erdene, K., Zhou, D., Gonzalez-Gutierrez, G., Ghozayel, M. K., Si, Y., Xu, D., Shannon, H. E., Bailey, B. J., Corson, T., Pollok, K., Wells, C. & Meroueh, S., Mar 21 2019, In : Cell Chemical Biology. 26, 3, p. 378-389.e13

Research output: Contribution to journalArticle

Palmitates
Glioblastoma
Cysteine
Cell Survival
Cells
8 Citations (Scopus)

Combination therapy in a xenograft model of glioblastoma: Enhancement of the antitumor activity of temozolomide by an MDM2 antagonist

Wang, H., Cai, S., Bailey, B. J., Saadatzadeh, M. R., Ding, J., Tonsing-Carter, E., Georgiadis, T. M., Gunter, T. Z., Long, E. C., Minto, R. E., Gordon, K. R., Sen, S. E., Cai, W., Eitel, J. A., Waning, D. L., Bringman, L. R., Wells, C., Murray, M. E., Sarkaria, J. N., Gelbert, L. M. & 5 others, Jones, D. R., Cohen-Gadol, A., Mayo, L., Shannon, H. E. & Pollok, K., Feb 1 2017, In : Journal of Neurosurgery. 126, 2, p. 446-459 14 p.

Research output: Contribution to journalArticle

temozolomide
Glioblastoma
Heterografts
Therapeutics
Growth
1 Citation (Scopus)

regSNPs-splicing: a tool for prioritizing synonymous single-nucleotide substitution

Zhang, X., Li, M., Lin, H., Rao, X., Feng, W., Yang, Y., Mort, M., Cooper, D. N., Wang, Y., Wang, Y., Wells, C., Zhou, Y. & Liu, Y., Apr 8 2017, (Accepted/In press) In : Human Genetics. p. 1-11 11 p.

Research output: Contribution to journalArticle

Nucleotides
Proteins
Protein Splicing
RNA Splicing
Nucleic Acid Conformation
14 Citations (Scopus)

Exploring the Existing Drug Space for Novel pTyr Mimetic and SHP2 Inhibitors

He, R., Yu, Z. H., Zhang, R. Y., Wu, L., Gunawan, A. M., Lane, B. S., Shim, J. S., Zeng, L. F., He, Y., Chen, L., Wells, C., Liu, J. O. & Zhang, Z-Y., Jul 9 2015, In : ACS Medicinal Chemistry Letters. 6, 7, p. 782-786 5 p.

Research output: Contribution to journalArticle

Phosphotyrosine
Protein Tyrosine Phosphatases
Cefsulodin
Amides
Acetic Acid