D. Clapp

  • 6522 Citations
  • 43 h-Index
1985 …2020
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  • 19 Similar Profiles
Neurofibromatosis 1 Medicine & Life Sciences
Fanconi Anemia Medicine & Life Sciences
Neurofibromin 1 Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Mast Cells Medicine & Life Sciences
Bone Marrow Medicine & Life Sciences
Neurofibroma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences

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NIH Grants 1989 2020

Developmental and HyperActive Ras Tumor SPORE

Clapp, D., Shannon, K. M., Nakamura, J., Skapek, S. & Johnson, G. L.

National Institutes of Health

9/1/158/31/20

Project: Research project

Plexiform Neurofibroma
Neurofibromatosis 1
Neoplasms
Molecular Biology
Clinical Trials

MOLECULAR CHARACTERIZATION OF PLATELET-ENDOTHELIAL ADHES

Clapp, D., Broxmeyer, H., McGraw, D., Srivastava, A. & Clapp, D.

National Institutes of Health

2/25/8911/30/19

Project: Research project

Hematologic Diseases
Genetic Therapy
Students
Research Personnel
Advisory Committees
Pediatrics
Medicine
Mentors
Research Personnel
Physicians

Publications 1985 2019

  • 6522 Citations
  • 43 h-Index
  • 128 Article
  • 4 Chapter
  • 2 Review article
  • 1 Editorial
1 Citation (Scopus)

A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas

Gehlhausen, J. R., Hawley, E., Wahle, B. M., He, Y., Edwards, D., Rhodes, S. D., Lajiness, J. D., Staser, K., Chen, S., Yang, X., Yuan, J., Li, X., Jiang, L., Smith, A., Bessler, W., Sandusky, G., Stemmer-Rachamimov, A., Stuhlmiller, T. J., Angus, S. P., Johnson, G. L. & 4 others, Nalepa, G., Yates, C., Clapp, D. & Park, S. J., Feb 15 2019, In : Human Molecular Genetics. 28, 4, p. 572-583 12 p.

Research output: Contribution to journalArticle

Neurilemmoma
Proteasome Endopeptidase Complex
Neurofibromin 2
Phosphotransferases
Schwann Cells
1 Citation (Scopus)

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation

Rhodes, S. D., He, Y., Smith, A., Jiang, L., Lu, Q., Mund, J., Li, X., Bessler, W., Qian, S., Dyer, W., Sandusky, G. E., Horvai, A. E., Armstrong, A. E. & Clapp, D., Aug 15 2019, In : Human molecular genetics. 28, 16, p. 2752-2762 11 p.

Research output: Contribution to journalArticle

Neurofibroma
Reading Frames
Neurofibromatosis 1
Plexiform Neurofibroma
Neoplasms

Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors

Bai, R. Y., Esposito, D., Tam, A. J., McCormick, F., Riggins, G. J., Clapp, D. & Staedtke, V., Jun 1 2019, In : Gene Therapy. 26, 6, p. 277-286 10 p.

Research output: Contribution to journalArticle

Neurofibromin 1
GTPase-Activating Proteins
Dependovirus
Genetic Therapy
Neurilemmoma
2 Citations (Scopus)

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

Wahle, B. M., Hawley, E. T., He, Y., Smith, A. E., Yuan, J., Masters, A. R., Jones, D. R., Gehlhausen, J. R., Park, S. J., Conway, S., Clapp, D. & Yates, C., Jan 1 2018, In : Oncotarget. 9, 1, p. 718-725 8 p.

Research output: Contribution to journalArticle

Celecoxib
Neurofibromatosis 2
Sensorineural Hearing Loss
Neurilemmoma
Neoplasms
6 Citations (Scopus)

Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis

Liao, C. P., Booker, R. C., Brosseau, J. P., Chen, Z., Mo, J., Tchegnon, E., Wang, Y., Clapp, D. & Le, L. Q., Jul 2 2018, In : Journal of Clinical Investigation. 128, 7, p. 2848-2861 14 p.

Research output: Contribution to journalArticle

Neurofibroma
Tumor Microenvironment
Carcinogenesis
Inflammation
Mast Cells