D. Clapp

  • 6723 Citations
  • 43 h-Index
1985 …2020
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  • 22 Similar Profiles
Neurofibromatosis 1 Medicine & Life Sciences
Fanconi Anemia Medicine & Life Sciences
Neurofibromin 1 Medicine & Life Sciences
Hematopoietic Stem Cells Medicine & Life Sciences
Mast Cells Medicine & Life Sciences
Neurofibroma Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Plexiform Neurofibroma Medicine & Life Sciences

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NIH Grants 1989 2020

Developmental and HyperActive Ras Tumor SPORE

Clapp, D., Shannon, K. M., Nakamura, J., Skapek, S. & Johnson, G. L.

National Institutes of Health

9/1/158/31/20

Project: Research project

Plexiform Neurofibroma
Neurofibromatosis 1
Neoplasms
Molecular Biology
Clinical Trials
Pediatrics
Medicine
Mentors
Research Personnel
Physicians

Genetic Therapy for Fanconi Anemia

Clapp, D., Hanenberg, H., Yang, F., Hanenberg, H. & Yang, F.

National Institutes of Health

2/1/1112/31/15

Project: Research project

Fanconi Anemia
Genetic Therapy
Stem Cells
Hematopoietic Stem Cells
Bone Marrow

Publications 1985 2019

  • 6723 Citations
  • 43 h-Index
  • 131 Article
  • 4 Chapter
  • 2 Review article
  • 1 Editorial
1 Citation (Scopus)

A proteasome-resistant fragment of NIK mediates oncogenic NF-κB signaling in schwannomas

Gehlhausen, J. R., Hawley, E., Wahle, B. M., He, Y., Edwards, D., Rhodes, S. D., Lajiness, J. D., Staser, K., Chen, S., Yang, X., Yuan, J., Li, X., Jiang, L., Smith, A., Bessler, W., Sandusky, G., Stemmer-Rachamimov, A., Stuhlmiller, T. J., Angus, S. P., Johnson, G. L. & 4 others, Nalepa, G., Yates, C., Clapp, D. & Park, S. J., Feb 15 2019, In : Human Molecular Genetics. 28, 4, p. 572-583 12 p.

Research output: Contribution to journalArticle

Neurilemmoma
Proteasome Endopeptidase Complex
Neurofibromin 2
Phosphotransferases
Schwann Cells
1 Citation (Scopus)

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation

Rhodes, S. D., He, Y., Smith, A., Jiang, L., Lu, Q., Mund, J., Li, X., Bessler, W., Qian, S., Dyer, W., Sandusky, G. E., Horvai, A. E., Armstrong, A. E. & Clapp, D. W., Aug 15 2019, In : Human molecular genetics. 28, 16, p. 2752-2762 11 p.

Research output: Contribution to journalArticle

Neurofibroma
Reading Frames
Neurofibromatosis 1
Plexiform Neurofibroma
Neoplasms
1 Citation (Scopus)

Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors

Bai, R. Y., Esposito, D., Tam, A. J., McCormick, F., Riggins, G. J., Clapp, D. & Staedtke, V., Jun 1 2019, In : Gene Therapy. 26, 6, p. 277-286 10 p.

Research output: Contribution to journalArticle

Neurofibromin 1
GTPase-Activating Proteins
Dependovirus
Genetic Therapy
Neurilemmoma

Ketotifen modulates mast cell chemotaxis to KIT-ligand, but does not impact mast cell numbers, degranulation, or tumor behavior in neurofibromas of NF1-deficient mice

Burks, C. A., Rhodes, S. D., Bessler, W. K., Chen, S., Smith, A., Gehlhausen, J. R., Hawley, E. T., Jiang, L., Li, X., Yuan, J., Lu, Q., Jacobsen, M., Sandusky, G. E., Jones, D. R., Clapp, D. W. & Blakeley, J. O., Jan 1 2019, In : Molecular cancer therapeutics. 18, 12, p. 2321-2330 10 p.

Research output: Contribution to journalArticle

Plexiform Neurofibroma
Ketotifen
Cell Degranulation
Neurofibroma
Neurofibromatosis 1

Multicenter, Prospective, Phase II and Biomarker Study of High-Dose Bevacizumab as Induction Therapy in Patients With Neurofibromatosis Type 2 and Progressive Vestibular Schwannoma

Plotkin, S. R., Duda, D. G., Muzikansky, A., Allen, J., Blakeley, J., Rosser, T., Campian, J. L., Clapp, D. W., Fisher, M. J., Tonsgard, J., Ullrich, N., Thomas, C., Cutter, G., Korf, B., Packer, R. & Karajannis, M. A., Dec 10 2019, In : Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 37, 35, p. 3446-3454 9 p.

Research output: Contribution to journalArticle

Neurofibromatosis 2
Acoustic Neuroma
Biomarkers
Hearing
Quality of Life