D. Clapp

  • 7068 Citations
  • 45 h-Index
1985 …2021

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2021
2020

A molecular basis for neurofibroma-associated skeletal manifestations in NF1

Ma, Y., Gross, A. M., Dombi, E., Pemov, A., Choi, K., Chaney, K., Rhodes, S. D., Angus, S. P., Sciaky, N., Clapp, D. W., Ratner, N., Widemann, B. C., Rios, J. J. & Elefteriou, F., 2020, (Accepted/In press) In : Genetics in Medicine.

Research output: Contribution to journalArticle

Early administration of imatinib mesylate reduces plexiform neurofibroma tumor burden with durable results after drug discontinuation in a mouse model of neurofibromatosis type 1

Armstrong, A. E., Rhodes, S. D., Smith, A., Chen, S., Bessler, W., Ferguson, M. J., Jiang, L., Li, X., Yuan, J., Yang, X., Yang, F. C., Robertson, K. A., Ingram, D. A., Blakeley, J. O. & Clapp, D. W., Aug 1 2020, In : Pediatric Blood and Cancer. 67, 8, e28372.

Research output: Contribution to journalArticle

Genetic disruption of the small GTPase RAC1 prevents plexiform neurofibroma formation in mice with neurofibromatosis type 17

Mund, J. A., Park, S. J., Smith, A. E., He, Y., Jiang, L., Hawley, E., Roberson, M. J., Mitchell, D. K., Abu-Sultanah, M., Yuan, J., Bessler, W. K., Sandusky, G., Chen, S., Zhang, C., Rhodes, S. D. & Clapp, D. W., Jul 17 2020, In : The Journal of biological chemistry. 295, 29, p. 9948-9958 11 p.

Research output: Contribution to journalArticle

Guanfacine treatment improves ADHD phenotypes of impulsivity and hyperactivity in a neurofibromatosis type 1 mouse model

Lukkes, J. L., Drozd, H. P., Fitz, S. D., Molosh, A. I., Clapp, D. W. & Shekhar, A., Jan 15 2020, In : Journal of Neurodevelopmental Disorders. 12, 1, 2.

Research output: Contribution to journalArticle

Open Access

Selumetinib in children with inoperable plexiform neurofibromas

Gross, A. M., Wolters, P. L., Dombi, E., Baldwin, A., Whitcomb, P., Fisher, M. J., Weiss, B., Kim, A. R., Bornhorst, M., Shah, A. C., Martin, S., Roderick, M. C., Pichard, D. C., Carbonell, A., Paul, S. M., Therrien, J., Kapustina, O., Heisey, K., Wade Clapp, D., Zhang, C. & 9 others, Peer, C. J., Figg, W. D., Smith, M., Glod, J., Blakeley, J. O., Steinberg, S. M., Venzon, D. J., Austin Doyle, L. & Widemann, B. C., Apr 9 2020, In : New England Journal of Medicine. 382, 15, p. 1430-1442 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
2019

A proteasome-resistant fragment of NIK mediates oncogenic NF-κ B signaling in schwannomas

Gehlhausen, J. R., Hawley, E., Wahle, B. M., He, Y., Edwards, D., Rhodes, S. D., Lajiness, J. D., Staser, K., Chen, S., Yang, X., Yuan, J., Li, X., Jiang, L., Smith, A., Bessler, W., Sandusky, G., Stemmer-Rachamimov, A., Stuhlmiller, T. J., Angus, S. P., Johnson, G. L. & 4 others, Nalepa, G., Yates, C. W., Wade Clapp, D. & Park, S. J., 2019, In : Human molecular genetics. 28, 4, p. 572-583 12 p.

Research output: Contribution to journalArticle

1 Scopus citations

Cdkn2a (Arf) loss drives NF1-associated atypical neurofibroma and malignant transformation

Rhodes, S. D., He, Y., Smith, A., Jiang, L., Lu, Q., Mund, J., Li, X., Bessler, W., Qian, S., Dyer, W., Sandusky, G. E., Horvai, A. E., Armstrong, A. E. & Clapp, D. W., Aug 15 2019, In : Human molecular genetics. 28, 16, p. 2752-2762 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Feasibility of using NF1-GRD and AAV for gene replacement therapy in NF1-associated tumors

Bai, R. Y., Esposito, D., Tam, A. J., McCormick, F., Riggins, G. J., Wade Clapp, D. & Staedtke, V., Jun 1 2019, In : Gene Therapy. 26, 6, p. 277-286 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Ketotifen modulates mast cell chemotaxis to KIT-ligand, but does not impact mast cell numbers, degranulation, or tumor behavior in neurofibromas of NF1-deficient mice

Burks, C. A., Rhodes, S. D., Bessler, W. K., Chen, S., Smith, A., Gehlhausen, J. R., Hawley, E. T., Jiang, L., Li, X., Yuan, J., Lu, Q., Jacobsen, M., Sandusky, G. E., Jones, D. R., Clapp, D. W. & Blakeley, J. O., 2019, In : Molecular cancer therapeutics. 18, 12, p. 2321-2330 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Multicenter, prospective, phase II and biomarker study of high-dose bevacizumab as induction therapy in patients with neurofibromatosis type 2 and progressive vestibular schwannoma

Plotkin, S. R., Duda, D. G., Muzikansky, A., Allen, J., Blakeley, J., Rosser, T., Campian, J. L., Wade Clapp, D., Fisher, M. J., Tonsgard, J., Ullrich, N., Thomas, C., Cutter, G., Korf, B., Packer, R. & Karajannis, M. A., 2019, In : Journal of Clinical Oncology. 37, 35, p. 3446-3454 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Subsequent neoplasms after a primary tumor in individuals with neurofibromatosis type 1

Bhatia, S., Chen, Y., Wong, F. L., Hageman, L., Smith, K., Korf, B., Cannon, A., Leidy, D. J., Paz, A., Andress, J. E., Friedman, G. K., Metrock, K., Neglia, J. P., Arnold, M., Turcotte, L. M., De Blank, P., Leisenring, W., Armstrong, G. T., Robison, L. L., Clapp, D. W. & 3 others, Shannon, K., Nakamura, J. L. & Fisher, M. J., 2019, In : Journal of Clinical Oncology. 37, 32, p. 3050-3058 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
2018

Chemopreventative celecoxib fails to prevent schwannoma formation or sensorineural hearing loss in genetically engineered murine model of neurofibromatosis type 2

Wahle, B. M., Hawley, E. T., He, Y., Smith, A. E., Yuan, J., Masters, A. R., Jones, D. R., Gehlhausen, J. R., Park, S. J., Conway, S. J., Clapp, D. W. & Yates, C. W., 2018, In : Oncotarget. 9, 1, p. 718-725 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis

Liao, C. P., Booker, R. C., Brosseau, J. P., Chen, Z., Mo, J., Tchegnon, E., Wang, Y., Clapp, D. W. & Le, L. Q., Jul 2 2018, In : Journal of Clinical Investigation. 128, 7, p. 2848-2861 14 p.

Research output: Contribution to journalArticle

25 Scopus citations

Traditional and systems biology based drug discovery for the rare tumor syndrome neurofibromatosis type 2

Allaway, R., Angus, S. P., Beauchamp, R. L., Blakeley, J. O., Bott, M., Burns, S. S., Carlstedt, A., Chang, L. S., Chen, X., Clapp, D. W., DeSouza, P. A., Erdin, S., Fernandez-Valle, C., Guinney, J., Gusella, J. F., Haggarty, S. J., Johnson, G. L., La Rosa, S., Morrison, H., Petrilli, A. M. & 11 others, Plotkin, S. R., Pratap, A., Ramesh, V., Sciaky, N., Stemmer-Rachamimov, A., Stuhlmiller, T. J., Talkowski, M. E., Welling, D. B., Yates, C. W., Zawistowski, J. S. & Zhao, W. N., Jun 2018, In : PloS one. 13, 6, e0197350.

Research output: Contribution to journalArticle

5 Scopus citations
2017

An abnormal bone marrow microenvironment contributes to hematopoietic dysfunction in fanconi anemia

Zhou, Y., He, Y., Xing, W., Zhang, P., Shi, H., Chen, S., Shi, J., Bai, J., Rhodes, S. D., Zhang, F., Yuan, J., Yang, X., Zhu, X., Li, Y., Hanenberg, H., Xu, M., Robertson, K. A., Yuan, W., Nalepa, G., Cheng, T. & 2 others, Clapp, D. W. & Yang, F-C., 2017, In : Haematologica. 102, 6, p. 1017-1027 11 p.

Research output: Contribution to journalArticle

15 Scopus citations

The path forward: 2015 International Children's Tumor Foundation conference on neurofibromatosis type 1, type 2, and schwannomatosis

Blakeley, J. O., Bakker, A., Barker, A., Clapp, W., Ferner, R., Fisher, M. J., Giovannini, M., Gutmann, D. H., Karajannis, M. A., Kissil, J. L., Legius, E., Lloyd, A. C., Packer, R. J., Ramesh, V., Riccardi, V. M., Stevenson, D. A., Ullrich, N. J., Upadhyaya, M. & Stemmer-Rachamimov, A., Jun 2017, In : American Journal of Medical Genetics, Part A. 173, 6, p. 1714-1721 8 p.

Research output: Contribution to journalArticle

5 Scopus citations
2016

Fanconi Anemia Proteins Function in Mitophagy and Immunity

Sumpter, R., Sirasanagandla, S., Fernández, Á. F., Wei, Y., Dong, X., Franco, L., Zou, Z., Marchal, C., Lee, M. Y., Clapp, D. W., Hanenberg, H. & Levine, B., May 5 2016, In : Cell. 165, 4, p. 867-881 15 p.

Research output: Contribution to journalArticle

100 Scopus citations

Preclinical Evidence for the Use of Sunitinib Malate in the Treatment of Plexiform Neurofibromas

Ferguson, M. J., Rhodes, S. D., Jiang, L., Li, X., Yuan, J., Yang, X., Zhang, S., Vakili, S. T., Territo, P., Hutchins, G., Yang, F. C., Ingram, D. A., Clapp, D. W. & Chen, S., Feb 1 2016, In : Pediatric Blood and Cancer. 63, 2, p. 206-213 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Spatially- and temporally-controlled postnatal p53 knockdown cooperates with embryonic Schwann cell precursor Nf1 gene loss to promote malignant peripheral nerve sheath tumor formation

Hirbe, A. C., Dahiya, S., Friedmann-Morvinski, D., Verma, I. M., Wade Clapp, D. & Gutmann, D. H., 2016, In : Oncotarget. 7, 7, p. 7403-7414 12 p.

Research output: Contribution to journalArticle

10 Scopus citations

The importance of nerve microenvironment for schwannoma development

Schulz, A., Büttner, R., Hagel, C., Baader, S. L., Kluwe, L., Salamon, J., Mautner, V. F., Mindos, T., Parkinson, D. B., Gehlhausen, J. R., Clapp, D. W. & Morrison, H., Aug 1 2016, In : Acta Neuropathologica. 132, 2, p. 289-307 19 p.

Research output: Contribution to journalArticle

29 Scopus citations
2015

A murine model of neurofibromatosis type 2 that accurately phenocopies human schwannoma formation

Gehlhausen, J. R., Park, S. J., Hickox, A. E., Shew, M., Staser, K., Rhodes, S. D., Menon, K., Lajiness, J. D., Mwanthi, M., Yang, X., Yuan, J., Territo, P., Hutchins, G., Nalepa, G., Yang, F-C., Conway, S. J., Heinz, M. G., Stemmer-Rachamimov, A., Yates, C. W. & Clapp, D. W., Jan 1 2015, In : Human molecular genetics. 24, 1, p. 1-8 8 p., ddu414.

Research output: Contribution to journalArticle

31 Scopus citations

Nf1+/- monocytes/macrophages induce neointima formation via CCR2 activation

Bessler, W. K., Kim, G., Hudson, F. Z., Mund, J. A., Mali, R., Menon, K., Kapur, R., Clapp, D. W., Ingram, D. A. & Stansfield, B. K., Aug 17 2015, In : Human molecular genetics. 25, 6, p. 1129-1139 11 p.

Research output: Contribution to journalArticle

8 Scopus citations

Pak2 regulates hematopoietic progenitor cell proliferation, survival, and differentiation

Zeng, Y., Broxmeyer, H. E., Staser, K., Chitteti, B. R., Park, S. J., Hahn, S., Cooper, S., Sun, Z., Jiang, L., Yang, X., Yuan, J., Kosoff, R., Sandusky, G., Srour, E. F., Chernoff, J. & Clapp, D. W., May 1 2015, In : STEM CELLS. 33, 5, p. 1630-1641 12 p.

Research output: Contribution to journalArticle

16 Scopus citations
2014

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies

Widemann, B. C., Acosta, M. T., Ammoun, S., Belzberg, A. J., Bernards, A., Blakeley, J., Bretscher, A., Cichowski, K., Clapp, D. W., Dombi, E., Evans, G. D., Ferner, R., Fernandez-Valle, C., Fisher, M. J., Giovannini, M., Gutmann, D. H., Hanemann, C. O., Hennigan, R., Huson, S., Ingram, D. & 19 others, Kissil, J., Korf, B. R., Legius, E., Packer, R. J., Mcclatchey, A. I., Mccormick, F., North, K., Pehrsson, M., Plotkin, S. R., Ramesh, V., Ratner, N., Schirmer, S., Sherman, L., Schorry, E., Stevenson, D., Stewart, D. R., Ullrich, N., Bakker, A. C. & Morrison, H., Mar 2014, In : American Journal of Medical Genetics, Part A. 164, 3, p. 563-578 16 p.

Research output: Contribution to journalArticle

17 Scopus citations

Fanconi anemia and the cell cycle: New perspectives on aneuploidy

Nalepa, G. & Wade Clapp, D., Apr 1 2014, In : F1000Prime Reports. 6

Research output: Contribution to journalArticle

18 Scopus citations

Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo

Li, F., Downing, B. D., Smiley, L. C., Mund, J. A., DiStasi, M. R., Bessler, W. K., Sarchet, K. N., Hinds, D. M., Kamendulis, L. M., Hingtgen, C. M., Case, J., Clapp, D. W., Conway, S. J., Stansfield, B. K. & Ingram, D. A., Jan 1 2014, In : Circulation. 129, 11, p. 1213-1224 12 p.

Research output: Contribution to journalArticle

15 Scopus citations

PRC2 loss amplifies Ras-driven transcription and confers sensitivity to BRD4-based therapies

De Raedt, T., Beert, E., Pasmant, E., Luscan, A., Brems, H., Ortonne, N., Helin, K., Hornick, J. L., Mautner, V., Kehrer-Sawatzki, H., Clapp, W., Bradner, J., Vidaud, M., Upadhyaya, M., Legius, E. & Cichowski, K., Oct 9 2014, In : Nature. 514, 7521, p. 247-251 5 p.

Research output: Contribution to journalArticle

222 Scopus citations

Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase

Molosh, A. I., Johnson, P. L., Spence, J. P., Arendt, D., Federici, L. M., Bernabe, C., Janasik, S. P., Segu, Z. M., Khanna, R., Goswami, C., Zhu, W., Park, S. J., Li, L., Mechref, Y. S., Clapp, D. W. & Shekhar, A., Oct 28 2014, In : Nature Neuroscience. 17, 11, p. 1583-1590 8 p.

Research output: Contribution to journalArticle

66 Scopus citations
2013

A Pak1-PP2A-ERM signaling axis mediates F-actin rearrangement and degranulation in mast cells

Staser, K., Shew, M. A., Michels, E. G., Mwanthi, M. M., Yang, F. C., Clapp, D. W. & Park, S. J., Jan 2013, In : Experimental Hematology. 41, 1, p. 56-66.e2

Research output: Contribution to journalArticle

19 Scopus citations

Fanconi anemia signaling network regulates the spindle assembly checkpoint

Nalepa, G., Enzor, R., Sun, Z., Marchal, C., Park, S. J., Yang, Y., Tedeschi, L., Kelich, S., Hanenberg, H. & Clapp, D. W., Sep 3 2013, In : Journal of Clinical Investigation. 123, 9, p. 3839-3847 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk

Staser, K., Park, S. J., Rhodes, S. D., Zeng, Y., He, Y. Z., Shew, M. A., Gehlhausen, J. R., Cerabona, D., Menon, K., Chen, S., Sun, Z., Yuan, J., Ingram, D. A., Nalepa, G., Yang, F. C. & Clapp, D. W., Jan 2 2013, In : Journal of Clinical Investigation. 123, 1, p. 329-334 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Periostin downregulation is an early marker of inhibited neonatal murine lung alveolar septation

Ahlfeld, S. K., Gao, Y., Wang, J., Horgusluoglu, E., Bolanis, E., Clapp, D. W. & Conway, S. J., Jun 2013, In : Birth Defects Research Part A - Clinical and Molecular Teratology. 97, 6, p. 373-385 13 p.

Research output: Contribution to journalArticle

18 Scopus citations

The tumor suppressor CDKN3 controls mitosis

Nalepa, G., Barnholtz-Sloan, J., Enzor, R., Dey, D., He, Y., Gehlhausen, J. R., Lehmann, A. S., Park, S. J., Yang, Y., Yang, X., Chen, S., Guan, X., Chen, Y., Renbarger, J., Yang, F. C., Parada, L. F. & Clapp, W., Jun 2013, In : Journal of Cell Biology. 201, 7, p. 997-1012 16 p.

Research output: Contribution to journalArticle

49 Scopus citations
2012

Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: A phase 2 trial

Robertson, K. A., Nalepa, G., Yang, F-C., Bowers, D. C., Ho, C. Y., Hutchins, G. D., Croop, J. M., Vik, T. A., Denne, S. C., Parada, L. F., Hingtgen, C. M., Walsh, L. E., Yu, M., Pradhan, K. R., Edwards-Brown, M. K., Cohen, M. D., Fletcher, J. W., Travers, J. B., Staser, K. W., Lee, M. W. & 5 others, Sherman, M. R., Davis, C. J., Miller, L. C., Ingram, D. A. & Clapp, D. W., Dec 1 2012, In : The Lancet Oncology. 13, 12, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

113 Scopus citations

Inhibition of p21 activated kinase (PAK) reduces airway responsiveness in vivo and in vitro in murine and human airways

Hoover, W. C., Zhang, W., Xue, Z., Gao, H., Chernoff, J., Clapp, D. W., Gunst, S. J. & Tepper, R. S., Aug 10 2012, In : PloS one. 7, 8, e42601.

Research output: Contribution to journalArticle

15 Scopus citations
2011

Fanconi anemia D2 protein is an apoptotic target mediated by caspases

Park, S. J., Beck, B. D., Saadatzadeh, M. R., Haneline, L. S., Clapp, D. W. & Lee, S. H., Sep 2011, In : Journal of Cellular Biochemistry. 112, 9, p. 2383-2391 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibition or ablation of p21-activated kinase (PAK1) disrupts glucose homeostatic mechanisms in vivo

Wang, Z., Oh, E., Clapp, D. W., Chernoff, J. & Thurmond, D. C., Dec 2 2011, In : Journal of Biological Chemistry. 286, 48, p. 41359-41367 9 p.

Research output: Contribution to journalArticle

78 Scopus citations

Kinase suppressor of ras (ksr1) modulates multiple kit-ligand-dependent mast cell functions

Chen, M., Burgin, S., Staser, K., He, Y., Li, X., Robinson, M., Jiang, L., Chan, R. J., Ingram, D. & Clapp, D. W., Oct 1 2011, In : Experimental Hematology. 39, 10, p. 969-976 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Stem cell gene therapy for fanconi anemia: Report from the 1st international fanconi anemia gene therapy working group meeting

Tolar, J., Adair, J. E., Antoniou, M., Bartholomae, C. C., Becker, P. S., Blazar, B. R., Bueren, J., Carroll, T., Cavazzana-Calvo, M., Clapp, D. W., Dalgleish, R., Galy, A., Gaspar, H. B., Hanenberg, H., Von Kalle, C., Kiem, H. P., Lindeman, D., Naldini, L., Navarro, S., Renella, R. & 7 others, Rio, P., Sevilla, J., Schmidt, M., Verhoeyen, E., Wagner, J. E., Williams, D. A. & Thrasher, A. J., Jul 2011, In : Molecular Therapy. 19, 7, p. 1193-1198 6 p.

Research output: Contribution to journalArticle

37 Scopus citations

The haploinsufficient hematopoietic microenvironment is critical to the pathological fracture repair in murine models of neurofibromatosis type 1

Wu, X., Chen, S., He, Y., Rhodes, S. D., Mohammad, K. S., Li, X., Yang, X., Jiang, L., Nalepa, G., Snider, P., Robling, A. G., Clapp, D. W., Conway, S. J., Guise, T. A. & Yang, F-C., Sep 29 2011, In : PloS one. 6, 9, e24917.

Research output: Contribution to journalArticle

22 Scopus citations
2010

Genetic disruption of both Fancc and Fancg in mice recapitulates the hematopoietic manifestations of Fanconi anemia

Pulliam-Leath, A. C., Ciccone, S. L., Nalepa, G., Li, X., Si, Y., Miravalle, L., Smith, D., Yuan, J., Li, J., Anur, P., Orazi, A., Vance, G. H., Yang, F-C., Hanenberg, H., Bagby, G. C. & Clapp, D. W., Oct 21 2010, In : Blood. 116, 16, p. 2915-2920 6 p.

Research output: Contribution to journalArticle

31 Scopus citations

Human FANCC is hypomorphic in murine Fancc-deficient cells

Hays, L. E., Keeble, W. W., Yates, J. E., Rathbun, R. K., Koretsky, T., Olson, S. B., Sun, Z., Clapp, D. W. & Bagby, G. C., Sep 23 2010, In : Blood. 116, 12, p. 2057-2060 4 p.

Research output: Contribution to journalArticle

7 Scopus citations

Loss of SIMPL compromises TNF-α-dependent survival of hematopoietic progenitors

Benson, E. A., Goebl, M. G., Yang, F-C., Kapur, R., McClintick, J., Sanghani, S., Clapp, D. W. & Harrington, M. A., Feb 1 2010, In : Experimental Hematology. 38, 2, p. 71-81 11 p.

Research output: Contribution to journalArticle

4 Scopus citations

Nf1-/- Schwann cell-conditioned medium modulates mast cell degranulation by c-Kit-mediated hyperactivation of phosphatidylinositol 3-kinase

Chen, S., Burgin, S., McDaniel, A., Li, X., Yuan, J., Chen, M., Khalaf, W., Clapp, D. W. & Yang, F. C., Dec 2010, In : American Journal of Pathology. 177, 6, p. 3125-3132 8 p.

Research output: Contribution to journalArticle

23 Scopus citations
2009

P21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

Allen, J. D., Jaffer, Z. M., Park, S. J., Burgin, S., Hofmann, C., Sells, M. A., Chen, S., Derr-Yellin, E., Michels, E. G., McDaniel, A., Bessler, W. K., Ingram, D. A., Atkinson, S. J., Travers, J. B., Chernoff, J. & Clapp, D. W., Mar 19 2009, In : Blood. 113, 12, p. 2695-2705 11 p.

Research output: Contribution to journalArticle

87 Scopus citations

Ral overactivation in malignant peripheral nerve sheath tumors

Bodempudi, V., Yamoutpoor, F., Pan, W., Dudek, A. Z., Esfandyari, T., Piedra, M., Babovick-Vuksanovic, D., Woo, R. A., Mautner, V. F., Kluwe, L., Clapp, D. W., DeVries, G. H., Thomas, S. L., Kurtz, A., Parada, L. F. & Farassati, F., Jul 2009, In : Molecular and cellular biology. 29, 14, p. 3964-3974 11 p.

Research output: Contribution to journalArticle

43 Scopus citations
2008

AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice

Pulliam, A. C., Hobson, M. J., Ciccone, S. L., Li, Y., Chen, S., Srour, E. F., Yang, F. C., Broxmeyer, H. E. & Clapp, D. W., Sep 1 2008, In : Experimental Hematology. 36, 9, p. 1084-1090 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway

Lasater, E. A., Bessler, W. K., Mead, L. E., Horn, W. E., Clapp, D. W., Conway, S. J., Ingram, D. A. & Li, F., Aug 2008, In : Human molecular genetics. 17, 15, p. 2336-2344 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/-- and c-kit-Dependent Bone Marrow

Yang, F. C., Ingram, D. A., Chen, S., Zhu, Y., Yuan, J., Li, X., Yang, X., Knowles, S., Horn, W., Li, Y., Zhang, S., Yang, Y., Vakili, S. T., Yu, M., Burns, D., Robertson, K., Hutchins, G., Parada, L. F. & Clapp, D. W., Oct 31 2008, In : Cell. 135, 3, p. 437-448 12 p.

Research output: Contribution to journalArticle

243 Scopus citations