Daniela Matei

  • 6923 Citations
  • 41 h-Index
19952019
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Publications 1995 2019

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2019
19 Citations (Scopus)

Adjuvant chemotherapy plus radiation for locally advanced endometrial cancer

Matei, D., Filiaci, V., Randall, M. E., Mutch, D., Steinhoff, M. M., DiSilvestro, P. A., Moxley, K. M., Kim, Y. M., Powell, M. A., O’Malley, D. M., Spirtos, N. M., Small, W., Tewari, K. S., Richards, W. E., Nakayama, J., Matulonis, U. A., Huang, H. Q. & Miller, D. S., Jun 13 2019, In : New England Journal of Medicine. 380, 24, p. 2317-2326 10 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Endometrial Neoplasms
Radiation
Drug Therapy
Confidence Intervals
1 Citation (Scopus)

A novel aldh1a1 inhibitor targets cells with stem cell characteristics in ovarian cancer

Nwani, N. G., Condello, S., Wang, Y., Swetzig, W. M., Barber, E., Hurley, T. & Matei, D., Apr 1 2019, In : Cancers. 11, 4, 502.

Research output: Contribution to journalArticle

Open Access
Ovarian Neoplasms
Stem Cells
Aldehyde Dehydrogenase
DNA Damage
Cell Proliferation
3 Citations (Scopus)

Association of chemotherapy and radiotherapy sequence with overall survival in locoregionally advanced endometrial cancer

Goodman, C. R., Hatoum, S., Seagle, B. L. L., Donnelly, E. D., Barber, E. L., Shahabi, S., Matei, D. & Strauss, J. B., Jan 1 2019, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Radiotherapy
Drug Therapy
Survival
Therapeutics
2 Citations (Scopus)

Epithelial Mutations in Endometriosis: Link to Ovarian Cancer

Bulun, S. E., Wan, Y. & Matei, D., Mar 1 2019, In : Endocrinology. 160, 3, p. 626-638 13 p.

Research output: Contribution to journalArticle

Endometriosis
Ovarian Neoplasms
Mutation
Epithelial Cells
Estrogens
10 Citations (Scopus)

Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial

Moore, K. N., Secord, A. A., Geller, M. A., Miller, D. S., Cloven, N., Fleming, G. F., Wahner Hendrickson, A. E., Azodi, M., DiSilvestro, P., Oza, A. M., Cristea, M., Berek, J. S., Chan, J. K., Rimel, B. J., Matei, D., Li, Y., Sun, K., Luptakova, K., Matulonis, U. A. & Monk, B. J., May 1 2019, In : The Lancet Oncology. 20, 5, p. 636-648 13 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Therapeutics
niraparib
Homologous Recombination
Platinum

Significance of number of positive lymph nodes and size as prognostic factors of recurrence and overall survival in cervical cancer patients

Attiah, D. G., Helenowski, I., Refaat, T., Strauss, J. B., Shahabi, S., Lurain, J., Pineda, M., Nieves-Neira, W., Matei, D. & Donnelly, E. D., Jan 1 2019, In : European Journal of Gynaecological Oncology. 40, 4, p. 609-613 5 p.

Research output: Contribution to journalArticle

Uterine Cervical Neoplasms
Lymph Nodes
Recurrence
Survival
Radiotherapy
5 Citations (Scopus)

SiRNA Delivery Using Dithiocarbamate-Anchored Oligonucleotides on Gold Nanorods

Wang, J., Thomas, M., Lin, P., Cheng, J. X., Matei, D. & Wei, A., Feb 20 2019, In : Bioconjugate Chemistry. 30, 2, p. 443-453 11 p.

Research output: Contribution to journalArticle

Nanotubes
Oligonucleotides
RNA
Nanorods
Gold

Small Molecules Target the Interaction between Tissue Transglutaminase and Fibronectin

Sima, L. E., Yakubov, B., Zhang, S., Condello, S., Grigorescu, A. A., Nwani, N. G., Chen, L., Schiltz, G. E., Arvanitis, C., Zhang, Z. Y. & Matei, D., Jun 1 2019, In : Molecular cancer therapeutics. 18, 6, p. 1057-1068 12 p.

Research output: Contribution to journalArticle

Fibronectins
Ovarian Neoplasms
Cell-Matrix Junctions
Interferometry
Focal Adhesion Protein-Tyrosine Kinases
2 Citations (Scopus)

Updates on adjuvant chemotherapy and radiation therapy for endometrial cancer

Cowan, M., Strauss, J. B., Barber, E. L. & Matei, D., Feb 1 2019, In : Current opinion in obstetrics & gynecology. 31, 1, p. 31-37 7 p.

Research output: Contribution to journalArticle

Adjuvant Chemotherapy
Endometrial Neoplasms
Radiotherapy
Drug Therapy
Recurrence
2018
17 Citations (Scopus)

An effective epigenetic-PARP inhibitor combination therapy for breast and ovarian cancers independent of BRCA mutations

Pulliam, N., Fang, F., Ozes, A. R., Tang, J., Adewuyi, A., Keer, H., Lyons, J., Baylin, S. B., Matei, D., Nakshatri, H., Rassool, F. V., Miller, K. & Nephew, K., Jul 1 2018, In : Clinical Cancer Research. 24, 13, p. 3163-3175 13 p.

Research output: Contribution to journalArticle

Epigenomics
Ovarian Neoplasms
Breast Neoplasms
Mutation
Methyltransferases
15 Citations (Scopus)

A phase i clinical trial of guadecitabine and carboplatin in platinum-resistant, recurrent ovarian cancer: Clinical, pharmacokinetic, and pharmacodynamic analyses

Matei, D., Ghamande, S., Roman, L., Secord, A. A., Nemunaitis, J., Markham, M. J., Nephew, K., Jueliger, S., Oganesian, A., Naim, S., Su, X. Y., Keer, H., Azab, M. & Fleming, G. F., May 15 2018, In : Clinical Cancer Research. 24, 10, p. 2285-2293 9 p.

Research output: Contribution to journalArticle

Carboplatin
Platinum
Ovarian Neoplasms
Pharmacokinetics
Clinical Trials
13 Citations (Scopus)

Genomic and epigenomic signatures in ovarian cancer associated with resensitization to platinum drugs

Fang, F., Cardenas, H., Huang, H., Jiang, G., Perkins, S., Zhang, C., Keer, H. N., Liu, Y., Nephew, K. & Matei, D., Feb 1 2018, In : Cancer Research. 78, 3, p. 631-644 14 p.

Research output: Contribution to journalArticle

Platinum
Epigenomics
Ovarian Neoplasms
Pharmaceutical Preparations
DNA Repair
2 Citations (Scopus)

Hormonal strategies in gynecologic cancer: Bridging biology and therapy

Nieves-Neira, W., Kim, J. J. & Matei, D., Jan 1 2018, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Neoplasms
Therapeutics
5 Citations (Scopus)

IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells

Wang, Y., Zong, X., Mitra, S., Mitra, A. K., Matei, D. & Nephew, K. P., Dec 6 2018, In : JCI insight. 3, 23

Research output: Contribution to journalArticle

Open Access
Neoplastic Stem Cells
Platinum
Ovarian Neoplasms
Interleukin-6
Stem Cells
18 Citations (Scopus)

Long-term efficacy, tolerability and overall survival in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer treated with maintenance olaparib capsules following response to chemotherapy

Friedlander, M., Matulonis, U., Gourley, C., du Bois, A., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Shirinkin, V., Selle, F., Fielding, A., Lowe, E. S., McMurtry, E. L., Spencer, S., Rowe, P., Mann, H., Parry, D. & 1 others, Ledermann, J., Oct 30 2018, In : British Journal of Cancer. 119, 9, p. 1075-1085 11 p.

Research output: Contribution to journalArticle

Platinum
Ovarian Neoplasms
Capsules
Maintenance
Drug Therapy
14 Citations (Scopus)

Pembrolizumab in patients with programmed death ligand 1–positive advanced ovarian cancer: Analysis of KEYNOTE-028

Varga, A., Piha-Paul, S., Ott, P. A., Mehnert, J. M., Berton-Rigaud, D., Morosky, A., Yang, P., Ruman, J. & Matei, D., Jan 1 2018, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Ligands
Therapeutics
Research Personnel
Safety
3 Citations (Scopus)

Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity

Özeş, A. R., Pulliam, N., Ertosun, M. G., Yılmaz, Ö., Tang, J., Çopuroğlu, E., Matei, D., Özeş, O. N. & Nephew, K., Mar 26 2018, (Accepted/In press) In : Oncogene. p. 1-12 12 p.

Research output: Contribution to journalArticle

STAT3 Transcription Factor
Cyclic AMP-Dependent Protein Kinases
Transcriptional Activation
Phosphorylation
Ovarian Neoplasms
9 Citations (Scopus)

Tissue tranglutaminase regulates interactions between ovarian cancer stem cells and the tumor niche

Condello, S., Sima, L., Ivan, C., Cardenas, H., Schiltz, G., Mishra, R. K. & Matei, D., Jun 1 2018, In : Cancer Research. 78, 11, p. 2990-3001 12 p.

Research output: Contribution to journalArticle

Stem Cell Niche
Neoplastic Stem Cells
Ovarian Neoplasms
Fibronectins
Neoplasms
2017
7 Citations (Scopus)

Biodynamic imaging for phenotypic profiling of three-dimensional tissue culture

Sun, H., Merrill, D., An, R., Turek, J., Matei, D. & Nolte, D. D., Jan 1 2017, In : Journal of Biomedical Optics. 22, 1, 016007.

Research output: Contribution to journalArticle

biodynamics
Tissue culture
spheroids
Paclitaxel
Bioreactors
2016
15 Citations (Scopus)

EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cells

Cardenas, H., Zhao, J., Vieth, E., Nephew, K. & Matei, D., 2016, In : Oncotarget. 7, 51, p. 84453-84467 15 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Ovarian Neoplasms
Small Interfering RNA
Polycomb Repressive Complex 2
Chromatin Assembly and Disassembly
7 Citations (Scopus)

Intracellular Doppler Signatures of Platinum Sensitivity Captured by Biodynamic Profiling in Ovarian Xenografts

Merrill, D., An, R., Sun, H., Yakubov, B., Matei, D., Turek, J. & Nolte, D., Jan 6 2016, In : Scientific Reports. 6, 18821.

Research output: Contribution to journalArticle

Platinum
Heterografts
Cellular Spheroids
Nude Mice
Cell Line
119 Citations (Scopus)

Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells

Li, J., Condello, S., Thomes-Pepin, J., Ma, X., Xia, Y., Hurley, T., Matei, D. & Cheng, J. X., Jan 4 2016, (Accepted/In press) In : Cell Stem Cell.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Ovarian Neoplasms
Lipids
Therapeutics
Cell- and Tissue-Based Therapy
98 Citations (Scopus)

NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

Özeş, A. R., Miller, D. F., Özeş, O. N., Fang, F., Liu, Y., Matei, D., Huang, T. & Nephew, K., Apr 4 2016, (Accepted/In press) In : Oncogene.

Research output: Contribution to journalArticle

Antisense RNA
NF-kappa B
Cell Aging
Ovarian Neoplasms
DNA Damage
39 Citations (Scopus)

Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serous ovarian cancer and a BRCA mutation: Overall survival adjusted for postprogression poly(adenosine diphosphate ribose) polymerase inhibitor therapy

Matulonis, U. A., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Spencer, S., Parry, D., Grinsted, L. & Ledermann, J. A., 2016, (Accepted/In press) In : Cancer.

Research output: Contribution to journalArticle

Poly Adenosine Diphosphate Ribose
Platinum
Ovarian Neoplasms
Mutation
Survival
178 Citations (Scopus)

Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib maintenance monotherapy: an updated analysis from a randomised, placebo-controlled, double-blind, phase 2 trial

Ledermann, J. A., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Spencer, S., Rowe, P., Lowe, E., Hodgson, D., Sovak, M. A. & Matulonis, U., Nov 1 2016, In : The Lancet Oncology. 17, 11, p. 1579-1589 11 p.

Research output: Contribution to journalArticle

Platinum
Ovarian Neoplasms
Placebos
Maintenance
Survival
25 Citations (Scopus)

Quality of life during olaparib maintenance therapy in platinum-sensitive relapsed serous ovarian cancer

Ledermann, J. A., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Bennett, B., Parry, D., Spencer, S., Mann, H. & Matulonis, U., Nov 22 2016, In : British Journal of Cancer. 115, 11, p. 1313-1320 8 p.

Research output: Contribution to journalArticle

Platinum
Ovarian Neoplasms
Quality of Life
Placebos
Therapeutics
11 Citations (Scopus)

Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer

Lee, J., Yakubov, B., Ivan, C., Jones, D. R., Caperell-Grant, A., Fishel, M., Cardenas, H. & Matei, D., 2016, In : Neoplasia (United States). 18, 11, p. 689-698 10 p.

Research output: Contribution to journalArticle

gemcitabine
Pancreatic Neoplasms
Adenocarcinoma
Neoplasms
Tumor Microenvironment
12 Citations (Scopus)

Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer

de Leon, M., Cardenas, H., Vieth, E., Emerson, R., Segar, M., Liu, Y., Nephew, K. & Matei, D., Mar 23 2016, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

Platinum
Ovarian Neoplasms
DNA Methylation
Heterografts
Proteins
2015
25 Citations (Scopus)
decitabine
platinum
ovarian neoplasms
Carboplatin
Platinum
50 Citations (Scopus)

Circulating tumor cell detection using a parallel flow micro-aperture chip system

Chang, C. L., Huang, W., Jalal, S., Chan, B. D., Mahmood, A., Shahda, S., O'Neil, B. H., Matei, D. & Savran, C. A., Apr 7 2015, In : Lab on a Chip - Miniaturisation for Chemistry and Biology. 15, 7, p. 1677-1688 12 p.

Research output: Contribution to journalArticle

Circulating Neoplastic Cells
Parallel flow
Tumors
Cells
Fluidics
5 Citations (Scopus)

Concurrent Detection of Cellular and Molecular Cancer Markers Using an Immunomagnetic Flow System

Huang, W., Chang, C. L., Chan, B. D., Jalal, S., Matei, D., Low, P. S. & Savran, C. A., Jul 12 2015, In : Analytical Chemistry. 87, 20, p. 10205-10212 8 p.

Research output: Contribution to journalArticle

Folic Acid
Blood
Throughput
Antigens
Molecules
12 Citations (Scopus)

High-Dose Chemotherapy for Recurrent Ovarian Germ Cell Tumors

Ammakkanavar, N. R., Matei, D., Abonour, R. & Einhorn, L., Oct 10 2015, In : Journal of Clinical Oncology. 33, 2, p. 226-227 2 p.

Research output: Contribution to journalArticle

Drug Administration Schedule
Antineoplastic Combined Chemotherapy Protocols
Salvage Therapy
Ifosfamide
Vinblastine
58 Citations (Scopus)

In vivo tumor growth of high-grade serous ovarian cancer cell lines

Mitra, A., Davis, D. A., Tomar, S., Roy, L., Gurler, H., Xie, J., Lantvit, D. D., Cardenas, H., Fang, F., Liu, Y., Loughran, E., Yang, J., Sharon Stack, M., Emerson, R., Cowden Dahl, K., Barbolina, M. V., Nephew, K., Matei, D. & Burdette, J. E., Aug 1 2015, In : Gynecologic Oncology. 138, 2, p. 372-377 6 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Cell Line
Growth
Neoplasms
Nude Mice
1 Citation (Scopus)

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial

Ledermann, J., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C. L., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Spencer, S., Dougherty, B., Orr, M., Hodgson, D., Barrett, J. C. & Matulonis, U., 2015, In : Obstetrical and Gynecological Survey. 69, 10, p. 594-596 3 p.

Research output: Contribution to journalArticle

Platinum
Ovarian Neoplasms
Therapeutics
olaparib
44 Citations (Scopus)

Postoperative Radiation Therapy for Endometrial Cancer: American Society of Clinical Oncology Clinical Practice Guideline Endorsement of the American Society for Radiation Oncology Evidence-Based Guideline

Meyer, L. A., Bohlke, K., Powell, M. A., Fader, A. N., Franklin, G. E., Lee, L. J., Matei, D., Coallier, L. & Wright, A. A., Sep 10 2015, In : Journal of Clinical Oncology. 33, 26, p. 2908-2913 6 p.

Research output: Contribution to journalArticle

Radiation Oncology
Endometrial Neoplasms
Practice Guidelines
Radiotherapy
Guidelines
30 Citations (Scopus)

Tissue transglutaminase mediated tumor-stroma interaction promotes pancreatic cancer progression

Lee, J., Condello, S., Yakubov, B., Emerson, R., Caperell-Grant, A., Hitomi, K., Xie, J. & Matei, D., Oct 1 2015, In : Clinical Cancer Research. 21, 19, p. 4482-4493 12 p.

Research output: Contribution to journalArticle

Pancreatic Neoplasms
Neoplasms
Heterografts
Tumor Microenvironment
Enzymes
79 Citations (Scopus)

β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroids

Condello, S., Morgan, C. A., Nagdas, S., Cao, L., Turek, J., Hurley, T. & Matei, D., Apr 30 2015, In : Oncogene. 34, 18, p. 2297-2308 12 p.

Research output: Contribution to journalArticle

Catenins
Ovarian Neoplasms
Anoikis
Neoplasms
Neoplastic Stem Cells
2014
14 Citations (Scopus)

Adjuvant therapy for endometrial cancer

DeLeon, M. C., Ammakkanavar, N. R. & Matei, D., 2014, In : Journal of Gynecologic Oncology. 25, 2, p. 136-147 12 p.

Research output: Contribution to journalArticle

Endometrial Neoplasms
Uterine Neoplasms
Gynecology
Obstetrics
Therapeutics
42 Citations (Scopus)

An open-label phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) with bevacizumab in patients with advanced cancer

Gordon, M. S., Robert, F., Matei, D., Mendelson, D. S., Goldman, J. W., Chiorean, E. G., Strother, R. M., Seon, B. K., Figg, W. D., Peer, C. J., Alvarez, D., Adams, B. J., Theuer, C. P. & Rosen, L. S., Dec 1 2014, In : Clinical Cancer Research. 20, 23, p. 5918-5926 9 p.

Research output: Contribution to journalArticle

Anti-Idiotypic Antibodies
Neoplasms
Vascular Endothelial Growth Factor A
Endoglin
TRC105
19 Citations (Scopus)

Decitabine reactivated pathways in platinum resistant ovarian cancer

Fang, F., Zuo, Q., Pilrose, J., Wang, Y., Shen, C., Li, M., Wulfridge, P., Matei, D. & Nephew, K., 2014, In : Oncotarget. 5, 11, p. 3579-3589 11 p.

Research output: Contribution to journalArticle

decitabine
Platinum
Ovarian Neoplasms
Gene Expression Profiling
Neoplasms

Endoglin for targeted cancer treatment.

Rosen, L. S., Gordon, M. S., Robert, F. & Matei, D. E., 2014, In : Current Oncology Reports. 16, 2, p. 365 1 p.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Neoplasms
Sarcoma
Endothelial Cells
Therapeutics
42 Citations (Scopus)

Endoglin for targeted cancer treatment topical collection on evolving therapies

Rosen, L. S., Gordon, M. S., Robert, F. & Matei, D., 2014, In : Current Oncology Reports. 16, 2, 365.

Research output: Contribution to journalArticle

Vascular Endothelial Growth Factor A
Neoplasms
Sarcoma
Endothelial Cells
Therapeutics
72 Citations (Scopus)

Epigenetic targeting of ovarian cancer stem cells

Wang, Y., Cardenas, H., Fang, F., Condello, S., Taverna, P., Segar, M., Liu, Y., Nephew, K. & Matei, D., Sep 1 2014, In : Cancer Research. 74, 17, p. 4922-4936 15 p.

Research output: Contribution to journalArticle

Neoplastic Stem Cells
Epigenomics
Ovarian Neoplasms
Aldehyde Dehydrogenase
Platinum
92 Citations (Scopus)

Epithelial ovarian cancer experimental models

Lengyel, E., Burdette, J. E., Kenny, H. A., Matei, D., Pilrose, J., Haluska, P., Nephew, K., Hales, D. B. & Stack, M. S., Jul 10 2014, In : Oncogene. 33, 28, p. 3619-3633 15 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Theoretical Models
Neoplasm Metastasis
Tumor Microenvironment
Genetic Models
10 Citations (Scopus)

High-throughput immunomagnetic cell detection using a microaperture chip system

Chang, C. L., Jalal, S., Huang, W., Mahmood, A., Matei, D. & Savran, C. A., 2014, In : IEEE Sensors Journal. 14, 9, p. 3008-3013 6 p., 6808412.

Research output: Contribution to journalArticle

Blood
chips
Cells
Throughput
Parallel flow
34 Citations (Scopus)

Intravenous aflibercept in patients with platinum-resistant, advanced ovarian cancer: Results of a randomized, double-blind, phase 2, parallel-arm study

Tew, W. P., Colombo, N., Ray-Coquard, I., Del Campo, J. M., Oza, A., Pereira, D., Mammoliti, S., Matei, D., Scambia, G., Tonkin, K., Shun, Z., Sternas, L. & Spriggs, D. R., Feb 1 2014, In : Cancer. 120, 3, p. 335-343 9 p.

Research output: Contribution to journalArticle

Platinum
Ovarian Neoplasms
Advisory Committees
Disease Progression
Fallopian Tube Neoplasms
41 Citations (Scopus)

MiR-378 as a biomarker for response to anti-angiogenic treatment in ovarian cancer

Chan, J. K., Kiet, T. K., Blansit, K., Ramasubbaiah, R., Hilton, J. F., Kapp, D. S. & Matei, D., 2014, In : Gynecologic Oncology. 133, 3, p. 568-574 7 p.

Research output: Contribution to journalArticle

Ovarian Neoplasms
Activated-Leukocyte Cell Adhesion Molecule
Biomarkers
Disease-Free Survival
Atlases
697 Citations (Scopus)

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial

Ledermann, J., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C. L., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Spencer, S., Dougherty, B., Orr, M., Hodgson, D., Barrett, J. C. & Matulonis, U., 2014, In : The Lancet Oncology. 15, 8, p. 852-861 10 p.

Research output: Contribution to journalArticle

Platinum
Ovarian Neoplasms
Placebos
Therapeutics
Mutation
21 Citations (Scopus)

Small molecule inhibitors target the tissue transglutaminase and fibronectin interaction

Yakubov, B., Chen, L., Belkin, A. M., Zhang, S., Chelladurai, B., Zhang, Z-Y. & Matei, D., Feb 20 2014, In : PLoS One. 9, 2, e89285.

Research output: Contribution to journalArticle

protein-glutamine gamma-glutamyltransferase
fibronectins
Fibronectins
Cell adhesion
cell adhesion
67 Citations (Scopus)

TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

Cardenas, H., Vieth, E., Lee, J., Segar, M., Liu, Y., Nephew, K. & Matei, D., Dec 18 2014, In : Epigenetics : official journal of the DNA Methylation Society. 9, 11, p. 1461-1472 12 p.

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
DNA Methylation
Ovarian Neoplasms
Methylation
Epigenomics