Daniela Matei

  • 7535 Citations
  • 44 h-Index
19952020

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2020

A Randomized Phase II Trial of Epigenetic Priming with Guadecitabine and Carboplatin in Platinum-resistant, Recurrent Ovarian Cancer

Oza, A. M., Matulonis, U. A., Secord, A. A., Nemunaitis, J., Roman, L. D., Blagden, S. P., Banerjee, S., McGuire, W. P., Ghamande, S., Birrer, M. J., Fleming, G. F., Markham, M. J., Hirte, H. W., Provencher, D. M., Basu, B., Kristeleit, R., Armstrong, D. K., Schwartz, B., Braly, P., Hall, G. D. & 8 others, Nephew, K. P., Jueliger, S., Oganesian, A., Naim, S., Hao, Y., Keer, H., Azab, M. & Matei, D., Mar 1 2020, In : Clinical Cancer Research. 26, 5, p. 1009-1016 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

Phase II Trial of Cabozantinib in Recurrent/Metastatic Endometrial Cancer: A Study of the Princess Margaret, Chicago, and California Consortia (NCI9322/PHL86)

Dhani, N. C., Hirte, H. W., Wang, L., Burnier, J. V., Jain, A., Butler, M. O., Welch, S., Fleming, G. F., Hurteau, J., Matsuo, K., Matei, D., Jimenez, W., Johnston, C., Cristea, M., Tonkin, K., Ghatage, P., Lheureux, S., Mehta, A., Quintos, J., Tan, Q. & 5 others, Kamel-Reid, S., Ludkovski, O., Tsao, M. S., Wright, J. J. & Oza, A. M., Jun 1 2020, In : Clinical Cancer Research. 26, 11, p. 2477-2486 10 p.

Research output: Contribution to journalArticle

1 Scopus citations

The Clinical Impact of Cancer Stem Cells

Lathia, J., Liu, H. & Matei, D., Feb 1 2020, In : Oncologist. 25, 2, p. 123-131 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
2019

Adjuvant chemotherapy plus radiation for locally advanced endometrial cancer

Matei, D., Filiaci, V., Randall, M. E., Mutch, D., Steinhoff, M. M., DiSilvestro, P. A., Moxley, K. M., Kim, Y. M., Powell, M. A., O’Malley, D. M., Spirtos, N. M., Small, W., Tewari, K. S., Richards, W. E., Nakayama, J., Matulonis, U. A., Huang, H. Q. & Miller, D. S., Jun 13 2019, In : New England Journal of Medicine. 380, 24, p. 2317-2326 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

A novel aldh1a1 inhibitor targets cells with stem cell characteristics in ovarian cancer

Nwani, N. G., Condello, S., Wang, Y., Swetzig, W. M., Barber, E., Hurley, T. & Matei, D., Apr 2019, In : Cancers. 11, 4, 502.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Association of chemotherapy and radiotherapy sequence with overall survival in locoregionally advanced endometrial cancer

Goodman, C. R., Hatoum, S., Seagle, B. L. L., Donnelly, E. D., Barber, E. L., Shahabi, S., Matei, D. & Strauss, J. B., Jan 1 2019, (Accepted/In press) In : Gynecologic Oncology.

Research output: Contribution to journalArticle

5 Scopus citations

Niraparib monotherapy for late-line treatment of ovarian cancer (QUADRA): a multicentre, open-label, single-arm, phase 2 trial

Moore, K. N., Secord, A. A., Geller, M. A., Miller, D. S., Cloven, N., Fleming, G. F., Wahner Hendrickson, A. E., Azodi, M., DiSilvestro, P., Oza, A. M., Cristea, M., Berek, J. S., Chan, J. K., Rimel, B. J., Matei, D. E., Li, Y., Sun, K., Luptakova, K., Matulonis, U. A. & Monk, B. J., May 2019, In : The lancet oncology. 20, 5, p. 636-648 13 p.

Research output: Contribution to journalArticle

39 Scopus citations

Pembrolizumab in patients with programmed death ligand 1–positive advanced ovarian cancer: Analysis of KEYNOTE-028

Varga, A., Piha-Paul, S., Ott, P. A., Mehnert, J. M., Berton-Rigaud, D., Morosky, A., Yang, P., Ruman, J. & Matei, D., Feb 2019, In : Gynecologic oncology. 152, 2, p. 243-250 8 p.

Research output: Contribution to journalArticle

30 Scopus citations

Significance of number of positive lymph nodes and size as prognostic factors of recurrence and overall survival in cervical cancer patients

Attiah, D. G., Helenowski, I., Refaat, T., Strauss, J. B., Shahabi, S., Lurain, J., Pineda, M., Nieves-Neira, W., Matei, D. & Donnelly, E. D., Jan 1 2019, In : European Journal of Gynaecological Oncology. 40, 4, p. 609-613 5 p.

Research output: Contribution to journalArticle

SiRNA Delivery Using Dithiocarbamate-Anchored Oligonucleotides on Gold Nanorods

Wang, J., Thomas, M., Lin, P., Cheng, J. X., Matei, D. E. & Wei, A., Feb 20 2019, In : Bioconjugate Chemistry. 30, 2, p. 443-453 11 p.

Research output: Contribution to journalArticle

5 Scopus citations

Small molecules target the interaction between tissue transglutaminase and fibronectin

Sima, L. E., Yakubov, B., Zhang, S., Condello, S., Grigorescu, A. A., Nwani, N. G., Chen, L., Schiltz, G. E., Arvanitis, C., Zhang, Z. Y. & Matei, D., Jan 1 2019, In : Molecular cancer therapeutics. 18, 6, p. 1057-1068 12 p.

Research output: Contribution to journalArticle

2018

An effective epigenetic-PARP inhibitor combination therapy for breast and ovarian cancers independent of BRCA mutations

Pulliam, N., Fang, F., Ozes, A. R., Tang, J., Adewuyi, A., Keer, H., Lyons, J., Baylin, S. B., Matei, D., Nakshatri, H., Rassool, F. V., Miller, K. D. & Nephew, K. P., Jul 1 2018, In : Clinical Cancer Research. 24, 13, p. 3163-3175 13 p.

Research output: Contribution to journalArticle

22 Scopus citations

A phase i clinical trial of guadecitabine and carboplatin in platinum-resistant, recurrent ovarian cancer: Clinical, pharmacokinetic, and pharmacodynamic analyses

Matei, D., Ghamande, S., Roman, L., Secord, A. A., Nemunaitis, J., Markham, M. J., Nephew, K. P., Jueliger, S., Oganesian, A., Naim, S., Su, X. Y., Keer, H., Azab, M. & Fleming, G. F., May 15 2018, In : Clinical Cancer Research. 24, 10, p. 2285-2293 9 p.

Research output: Contribution to journalArticle

22 Scopus citations

Genomic and epigenomic signatures in ovarian cancer associated with resensitization to platinum drugs

Fang, F., Cardenas, H., Huang, H., Jiang, G., Perkins, S. M., Zhang, C., Keer, H. N., Liu, Y., Nephew, K. P. & Matei, D., Feb 1 2018, In : Cancer Research. 78, 3, p. 631-644 14 p.

Research output: Contribution to journalArticle

21 Scopus citations

IL-6 mediates platinum-induced enrichment of ovarian cancer stem cells

Wang, Y., Zong, X., Mitra, S., Mitra, A. K., Matei, D. & Nephew, K. P., Dec 6 2018, In : JCI Insight. 3, 23

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Long-term efficacy, tolerability and overall survival in patients with platinum-sensitive, recurrent high-grade serous ovarian cancer treated with maintenance olaparib capsules following response to chemotherapy

Friedlander, M., Matulonis, U., Gourley, C., du Bois, A., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Shirinkin, V., Selle, F., Fielding, A., Lowe, E. S., McMurtry, E. L., Spencer, S., Rowe, P., Mann, H., Parry, D. & 1 others, Ledermann, J., Oct 30 2018, In : British Journal of Cancer. 119, 9, p. 1075-1085 11 p.

Research output: Contribution to journalArticle

31 Scopus citations

Protein kinase A-mediated phosphorylation regulates STAT3 activation and oncogenic EZH2 activity

Özeş, A. R., Pulliam, N., Ertosun, M. G., Yllmaz, Ö., Tang, J., Çopuroǧlu, E., Matei, D., Özeş, O. N. & Nephew, K. P., Jun 1 2018, In : Oncogene. 37, 26, p. 3589-3600 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Tissue tranglutaminase regulates interactions between ovarian cancer stem cells and the tumor niche

Condello, S., Sima, L., Ivan, C., Cardenas, H., Schiltz, G., Mishra, R. K. & Matei, D., Jun 1 2018, In : Cancer Research. 78, 11, p. 2990-3001 12 p.

Research output: Contribution to journalArticle

11 Scopus citations
2017

Biodynamic imaging for phenotypic profiling of three-dimensional tissue culture

Sun, H., Merrill, D., An, R., Turek, J., Matei, D. & Nolte, D. D., Jan 1 2017, In : Journal of Biomedical Optics. 22, 1, 016007.

Research output: Contribution to journalArticle

8 Scopus citations

Lipid Desaturation Is a Metabolic Marker and Therapeutic Target of Ovarian Cancer Stem Cells

Li, J., Condello, S., Thomes-Pepin, J., Ma, X., Xia, Y., Hurley, T. D., Matei, D. & Cheng, J. X., Mar 2 2017, In : Cell Stem Cell. 20, 3, p. 303-314.e5

Research output: Contribution to journalArticle

134 Scopus citations
2016

EZH2 inhibition promotes epithelial-to-mesenchymal transition in ovarian cancer cells

Cardenas, H., Zhao, J., Vieth, E., Nephew, K. P. & Matei, D., Jan 1 2016, In : Oncotarget. 7, 51, p. 84453-84467 15 p.

Research output: Contribution to journalArticle

18 Scopus citations

Intracellular Doppler Signatures of Platinum Sensitivity Captured by Biodynamic Profiling in Ovarian Xenografts

Merrill, D., An, R., Sun, H., Yakubov, B., Matei, D., Turek, J. & Nolte, D., Jan 6 2016, In : Scientific reports. 6, 18821.

Research output: Contribution to journalArticle

8 Scopus citations

NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer

Özeş, A. R., Miller, D. F., Özeş, O. N., Fang, F., Liu, Y., Matei, D., Huang, T. & Nephew, K. P., Oct 13 2016, In : Oncogene. 35, 41, p. 5350-5361 12 p.

Research output: Contribution to journalArticle

118 Scopus citations

Olaparib maintenance therapy in patients with platinum-sensitive, relapsed serous ovarian cancer and a BRCA mutation: Overall survival adjusted for postprogression poly(adenosine diphosphate ribose) polymerase inhibitor therapy

Matulonis, U. A., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Spencer, S., Parry, D., Grinsted, L. & Ledermann, J. A., Jun 15 2016, In : Cancer. 122, 12, p. 1844-1852 9 p.

Research output: Contribution to journalArticle

44 Scopus citations

Overall survival in patients with platinum-sensitive recurrent serous ovarian cancer receiving olaparib maintenance monotherapy: an updated analysis from a randomised, placebo-controlled, double-blind, phase 2 trial

Ledermann, J. A., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Spencer, S., Rowe, P., Lowe, E., Hodgson, D., Sovak, M. A. & Matulonis, U., Nov 1 2016, In : The lancet oncology. 17, 11, p. 1579-1589 11 p.

Research output: Contribution to journalArticle

198 Scopus citations

Quality of life during olaparib maintenance therapy in platinum-sensitive relapsed serous ovarian cancer

Ledermann, J. A., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Bennett, B., Parry, D., Spencer, S., Mann, H. & Matulonis, U., Nov 22 2016, In : British Journal of Cancer. 115, 11, p. 1313-1320 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Tissue Transglutaminase Activates Cancer-Associated Fibroblasts and Contributes to Gemcitabine Resistance in Pancreatic Cancer

Lee, J., Yakubov, B., Ivan, C., Jones, D. R., Caperell-Grant, A., Fishel, M., Cardenas, H. & Matei, D., Jan 1 2016, In : Neoplasia (United States). 18, 11, p. 689-698 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Transmembrane protein 88 (TMEM88) promoter hypomethylation is associated with platinum resistance in ovarian cancer

de Leon, M., Cardenas, H., Vieth, E., Emerson, R., Segar, M., Liu, Y., Nephew, K. & Matei, D., Sep 1 2016, In : Gynecologic oncology. 142, 3, p. 539-547 9 p.

Research output: Contribution to journalArticle

16 Scopus citations
2015
27 Scopus citations

Circulating tumor cell detection using a parallel flow micro-aperture chip system

Chang, C. L., Huang, W., Jalal, S. I., Chan, B. D., Mahmood, A., Shahda, S., O'Neil, B. H., Matei, D. E. & Savran, C. A., Apr 7 2015, In : Lab on a Chip. 15, 7, p. 1677-1688 12 p.

Research output: Contribution to journalArticle

54 Scopus citations

Concurrent Detection of Cellular and Molecular Cancer Markers Using an Immunomagnetic Flow System

Huang, W., Chang, C. L., Chan, B. D., Jalal, S. I., Matei, D. E., Low, P. S. & Savran, C. A., Jul 12 2015, In : Analytical Chemistry. 87, 20, p. 10205-10212 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Global DNA methylation profiling technologies and the ovarian cancer methylome

Tang, J., Fang, F., Miller, D. F., Pilrose, J. M., Matei, D., Huang, T. H. M. & Nephew, K. P., Jan 1 2015, In : Methods in Molecular Biology. 1238, p. 653-675 23 p.

Research output: Contribution to journalArticle

12 Scopus citations

In vivo tumor growth of high-grade serous ovarian cancer cell lines

Mitra, A. K., Davis, D. A., Tomar, S., Roy, L., Gurler, H., Xie, J., Lantvit, D. D., Cardenas, H., Fang, F., Liu, Y., Loughran, E., Yang, J., Sharon Stack, M., Emerson, R. E., Cowden Dahl, K. D., Barbolina, M. V., Nephew, K. P., Matei, D. & Burdette, J. E., Aug 1 2015, In : Gynecologic oncology. 138, 2, p. 372-377 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Postoperative radiation therapy for endometrial cancer: American society of clinical oncology clinical practice guideline endorsement of the American society for radiation oncology evidence-based guideline

Meyer, L. A., Bohlke, K., Powell, M. A., Fader, A. N., Franklin, G. E., Lee, L. J., Matei, D., Coallier, L. & Wright, A. A., Jan 1 2015, In : Journal of Clinical Oncology. 33, 26, p. 2908-2913 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Tissue transglutaminase mediated tumor-stroma interaction promotes pancreatic cancer progression

Lee, J., Condello, S., Yakubov, B., Emerson, R., Caperell-Grant, A., Hitomi, K., Xie, J. & Matei, D., Oct 1 2015, In : Clinical Cancer Research. 21, 19, p. 4482-4493 12 p.

Research output: Contribution to journalArticle

35 Scopus citations

β-Catenin-regulated ALDH1A1 is a target in ovarian cancer spheroids

Condello, S., Morgan, C. A., Nagdas, S., Cao, L., Turek, J., Hurley, T. D. & Matei, D., Apr 30 2015, In : Oncogene. 34, 18, p. 2297-2308 12 p.

Research output: Contribution to journalArticle

88 Scopus citations
2014

An open-label phase Ib dose-escalation study of TRC105 (anti-endoglin antibody) with bevacizumab in patients with advanced cancer

Gordon, M. S., Robert, F., Matei, D., Mendelson, D. S., Goldman, J. W., Chiorean, E. G., Strother, R. M., Seon, B. K., Figg, W. D., Peer, C. J., Alvarez, D., Adams, B. J., Theuer, C. P. & Rosen, L. S., Dec 1 2014, In : Clinical Cancer Research. 20, 23, p. 5918-5926 9 p.

Research output: Contribution to journalArticle

47 Scopus citations

Decitabine reactivated pathways in platinum resistant ovarian cancer

Fang, F., Zuo, Q., Pilrose, J., Wang, Y., Shen, C., Li, M., Wulfridge, P., Matei, D. & Nephew, K. P., 2014, In : Oncotarget. 5, 11, p. 3579-3589 11 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Endoglin for targeted cancer treatment.

Rosen, L. S., Gordon, M. S., Robert, F. & Matei, D. E., 2014, In : Current Oncology Reports. 16, 2, p. 365 1 p.

Research output: Contribution to journalArticle

Endoglin for targeted cancer treatment topical collection on evolving therapies

Rosen, L. S., Gordon, M. S., Robert, F. & Matei, D. E., Feb 2014, In : Current oncology reports. 16, 2, 365.

Research output: Contribution to journalArticle

46 Scopus citations

Epigenetic targeting of ovarian cancer stem cells

Wang, Y., Cardenas, H., Fang, F., Condello, S., Taverna, P., Segar, M., Liu, Y., Nephew, K. P. & Matei, D., Sep 1 2014, In : Cancer Research. 74, 17, p. 4922-4936 15 p.

Research output: Contribution to journalArticle

77 Scopus citations

High-throughput immunomagnetic cell detection using a microaperture chip system

Chang, C. L., Jalal, S. I., Huang, W., Mahmood, A., Matei, D. E. & Savran, C. A., Sep 2014, In : IEEE Sensors Journal. 14, 9, p. 3008-3013 6 p., 6808412.

Research output: Contribution to journalArticle

12 Scopus citations

Intravenous aflibercept in patients with platinum-resistant, advanced ovarian cancer: Results of a randomized, double-blind, phase 2, parallel-arm study

Tew, W. P., Colombo, N., Ray-Coquard, I., Del Campo, J. M., Oza, A., Pereira, D., Mammoliti, S., Matei, D., Scambia, G., Tonkin, K., Shun, Z., Sternas, L. & Spriggs, D. R., Feb 1 2014, In : Cancer. 120, 3, p. 335-343 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

MiR-378 as a biomarker for response to anti-angiogenic treatment in ovarian cancer

Chan, J. K., Kiet, T. K., Blansit, K., Ramasubbaiah, R., Hilton, J. F., Kapp, D. S. & Matei, D., Jun 2014, In : Gynecologic oncology. 133, 3, p. 568-574 7 p.

Research output: Contribution to journalArticle

46 Scopus citations

Olaparib maintenance therapy in patients with platinum-sensitive relapsed serous ovarian cancer: A preplanned retrospective analysis of outcomes by BRCA status in a randomised phase 2 trial

Ledermann, J., Harter, P., Gourley, C., Friedlander, M., Vergote, I., Rustin, G., Scott, C. L., Meier, W., Shapira-Frommer, R., Safra, T., Matei, D., Fielding, A., Spencer, S., Dougherty, B., Orr, M., Hodgson, D., Barrett, J. C. & Matulonis, U., Jul 2014, In : The Lancet Oncology. 15, 8, p. 852-861 10 p.

Research output: Contribution to journalArticle

770 Scopus citations

Small molecule inhibitors target the tissue transglutaminase and fibronectin interaction

Yakubov, B., Chen, L., Belkin, A. M., Zhang, S., Chelladurai, B., Zhang, Z. Y. & Matei, D., Feb 20 2014, In : PloS one. 9, 2, e89285.

Research output: Contribution to journalArticle

22 Scopus citations

TGF-β induces global changes in DNA methylation during the epithelial-to-mesenchymal transition in ovarian cancer cells

Cardenas, H., Vieth, E., Lee, J., Segar, M., Liu, Y., Nephew, K. P. & Matei, D., Dec 18 2014, In : Epigenetics. 9, 11, p. 1461-1472 12 p.

Research output: Contribution to journalArticle

71 Scopus citations

The novel, small-molecule DNA methylation inhibitor SGI-110 as an ovarian cancer chemosensitizer

Fang, F., Munck, J., Tang, J., Taverna, P., Wang, Y., Miller, D. F. B., Pilrose, J., Choy, G., Azab, M., Pawelczak, K. S., VanderVere-Carozza, P., Wagner, M., Lyons, J., Matei, D., Turchi, J. J. & Nephew, K. P., Dec 15 2014, In : Clinical Cancer Research. 20, 24, p. 6504-6516 13 p.

Research output: Contribution to journalArticle

58 Scopus citations
2013

ENMD-2076, an oral inhibitor of angiogenic and proliferation kinases, has activity in recurrent, platinum resistant ovarian cancer

Matulonis, U. A., Lee, J., Lasonde, B., Tew, W. P., Yehwalashet, A., Matei, D., Behbakht, K., Grothusen, J., Fleming, G., Lee, N. K., Arnott, J., Bray, M. R., Fletcher, G., Brokx, R. D., Castonguay, V., MacKay, H., Sidor, C. F. & Oza, A. M., Jan 1 2013, In : European Journal of Cancer. 49, 1, p. 121-131 11 p.

Research output: Contribution to journalArticle

28 Scopus citations

Extracellular tissue transglutaminase activates noncanonical NF-κB signaling and promotes metastasis in ovarian cancer

Yakubov, B., Chelladurai, B., Schmitt, J., Emerson, R., Turchi, J. J. & Matei, D., Jan 1 2013, In : Neoplasia (United States). 15, 6, p. 609-619 11 p.

Research output: Contribution to journalArticle

35 Scopus citations