Darron Brown

  • 10638 Citations
  • 41 h-Index
1988 …2019

Research output per year

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Publications

2009

Prevalence and persistence of cervical human papillomavirus infection in HIV-positive women initiating highly active antiretroviral therapy

Fife, K. H., Wu, J. W., Squires, K. E., Watts, D. H., Andersen, J. W. & Brown, D. R., Jul 1 2009, In : Journal of Acquired Immune Deficiency Syndromes. 51, 3, p. 274-282 9 p.

Research output: Contribution to journalArticle

41 Scopus citations

The impact of quadrivalent human papillomavirus (HPV; Types 6, 11, 16, and 18) L1 virus-like particle vaccine on infection and disease due to oncogenic nonvaccine HPV types in generally HPV-naive women aged 16-26 years

Brown, D. R., Kjaer, S. K., Sigurdsson, K., Iversen, O. E., Mauricio, H. A., Wheeler, C. M., Perez, G., Koutsky, L. A., Tay, E. H., Garcia, P., Ault, K. A., Garland, S. M., Leodolter, S., Olsson, S. E., Tang, G. W. K., Ferris, D. G., Paavonen, J., Steben, M., Bosch, F. X., Dillner, J. & 16 others, Joura, E. A., Kurman, R. J., Majewski, S., Muñoz, N., Myers, E. R., Villa, L. L., Taddeo, F. J., Roberts, C., Tadesse, A., Bryan, J., Lupinacci, L. C., Giacoletti, K. E. D., Sings, H. L., James, M., Hesley, T. M. & Barra, E., Apr 1 2009, In : Journal of Infectious Diseases. 199, 7, p. 926-935 10 p.

Research output: Contribution to journalArticle

435 Scopus citations

The impact of quadrivalent human papillomavirus (HPV; Types 6, 11, 16, and 18) L1 virus-like particle vaccine on infection and disease due to oncogenic nonvaccine hpv types in sexually active women aged 16-26 years

Wheeler, C. M., Kjaer, S. K., Sigurdsson, K., Iversen, O. E., Mauricio, H. A., Perez, G., Brown, D. R., Koutsky, L. A., Tay, E. H., García, P., Ault, K. A., Garland, S. M., Leodolter, S., Olsson, S. E., Tang, G. W. K., Ferris, D. G., Paavonen, J., Steben, M., Bosch, F. X., Dillner, J. & 16 others, Joura, E. A., Kurman, R. J., Majewski, S., Muñoz, N., Myers, E. R., Villa, L. L., Taddeo, F. J., Roberts, C., Tadesse, A., Bryan, J., Lupinacci, L. C., Giacoletti, K. E. D., James, M., Vuocolo, S., Hesley, T. M. & Barra, E., Apr 1 2009, In : Journal of Infectious Diseases. 199, 7, p. 936-944 9 p.

Research output: Contribution to journalArticle

207 Scopus citations
2008

Baseline demographic characteristics of subjects enrolled in international quadrivalent HPV (types 6/11/16/18) vaccine clinical trials

Paavonen, J., Villa, L., Munoz, N., Perez, G., Krüger Kjaer, S., Paavonen, J., Lehtinen, M., Sigurdsson, K., Hernandez-Avila, M., Iversen, O. E., Garcia, P., Majewski, S., Tay, E. H., Bosch, F. X., Dillner, J., Olsson, S. E., Ault, K., Brown, D., Ferris, D., Koutsky, L. & 2 others, Kurman, R. & Myers, E., Jun 1 2008, In : Current Medical Research and Opinion. 24, 6, p. 1623-1634 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

HPV antibody levels and clinical efficacy following administration of a prophylactic quadrivalent HPV vaccine

Joura, E. A., Kjaer, S. K., Wheeler, C. M., Sigurdsson, K., Iversen, O. E., Hernandez-Avila, M., Perez, G., Brown, D. R., Koutsky, L. A., Tay, E. H., García, P., Ault, K. A., Garland, S. M., Leodolter, S., Olsson, S. E., Tang, G. W. K., Ferris, D. G., Paavonen, J., Lehtinen, M., Steben, M. & 18 others, Bosch, X., Dillner, J., Kurman, R. J., Majewski, S., Muñoz, N., Myers, E. R., Villa, L. L., Taddeo, F. J., Roberts, C., Tadesse, A., Bryan, J., Lupinacci, L. C., Giacoletti, K. E. D., Lu, S., Vuocolo, S., Hesley, T. M., Haupt, R. M. & Barr, E., Dec 9 2008, In : Vaccine. 26, 52, p. 6844-6851 8 p.

Research output: Contribution to journalArticle

149 Scopus citations
2007

Antibodies from women immunized with Gardasil® cross-neutralize HPV 45 pseudovirions

Smith, J. F., Brownlow, M., Brown, M., Kowalski, R., Esser, M. T., Ruiz, W., Barr, E., Brown, D. R. & Bryan, J. T., Jan 1 2007, In : Human Vaccines. 3, 4, p. 109-115 7 p.

Research output: Contribution to journalArticle

111 Scopus citations

Human papillomavirus genotypes associated with cervical cytologic abnormalities and HIV infection in Ugandan women

Blossom, D. B., Beigi, R. H., Farrell, J. J., Mackay, W., Qadadri, B., Brown, D. R., Rwambuya, S., Walker, C. J., Kambugu, F. S., Abdul-Karim, F. W., Whalen, C. C. & Salata, R. A., Jun 2007, In : Journal of Medical Virology. 79, 6, p. 758-765 8 p.

Research output: Contribution to journalArticle

46 Scopus citations

Prophylactic efficacy of a quadrivalent human papillomavirus (HPV) vaccine in women with virological evidence of HPV Infection

Villa, L. L., Perez, G., Kjær, S. K., Paavonen, J., Lehtinen, M., Muñoz, N., Sigurdsson, K., Hernandez-Avila, M., Iversen, O. E., Thoresen, S., García, P. J., Majewski, S., Eng, H. T., Bosch, F. X., Dillner, J., Olsson, S. E., Ault, K. A., Brown, D. R., Ferris, D. G., Koutsky, L. A. & 14 others, Kurman, R. J., Myers, E. R., Barr, E., Boslego, J., Bryan, J., Esser, M. T., Hesley, T. M., Nelson, M., Railkar, R., James, M., Sattler, C., Taddeo, F. J., Thornton, A. R. & Vuocolo, S. C., Nov 15 2007, In : Journal of Infectious Diseases. 196, 10, p. 1438-1446 9 p.

Research output: Contribution to journalArticle

141 Scopus citations

Quadrivalent vaccine against human papillomavirus to prevent high-grade cervical lesions

Villa, L. L., Perez, G., Kjaer, S. K., Paavonen, J., Lehtinen, M., Muñoz, N., Sigurdsson, K., Hernandez-Avila, M., Skjeldestad, F. E., Thoresen, S., García, P., Majewski, S., Dillner, J., Olsson, S. E., Eng, H. T., Bosch, F. X., Ault, K. A., Brown, D. R., Ferris, D. G., Koutsky, L. A. & 12 others, Kurman, R. J., Myers, E. R., Barr, E., Boslego, J., Bryan, J., Esser, M. T., Gause, C. K., Hesley, T. M., Lupinacci, L. C., Sings, H. L., Taddeo, F. J. & Thornton, A. R., May 10 2007, In : New England Journal of Medicine. 356, 19, p. 1915-1927 13 p.

Research output: Contribution to journalArticle

1545 Scopus citations
2006
93 Scopus citations

Detection of specific human papillomavirus types in paraffin-embedded sections of cervical carcinomas

Bryan, J. T., Taddeo, F., Skulsky, D. M., Jansen, K. U., Frain, B. M., Qadadri, B. & Brown, D. R., Jan 1 2006, In : Journal of Medical Virology. 78, 1, p. 117-124 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Down-regulation of MHC class I is a property common to papillomavirus E5 proteins

Ashrafi, G. H., Brown, D. R., Fife, K. H. & Campo, M. S., Sep 1 2006, In : Virus Research. 120, 1-2, p. 208-211 4 p.

Research output: Contribution to journalArticle

46 Scopus citations

Efficacy of human papillomavirus-16 vaccine to prevent cervical intraepithelial neoplasia: A randomized controlled trial

Mao, C., Koutsky, L. A., Ault, K. A., Wheeler, C. M., Brown, D. R., Wiley, D. J., Alvarez, F. B., Bautista, O. M., Jansen, K. U. & Barr, E., Jan 2006, In : Obstetrics and gynecology. 107, 1, p. 18-27 10 p.

Research output: Contribution to journalArticle

415 Scopus citations

Immunologic responses following administration of a vaccine targeting human papillomavirus Types 6, 11, 16, and 18

Villa, L. L., Ault, K. A., Giuliano, A. R., Costa, R. L. R., Petta, C. A., Andrade, R. P., Brown, D. R., Ferenczy, A., Harper, D. M., Koutsky, L. A., Kurman, R. J., Lehtinen, M., Malm, C., Olsson, S. E., Ronnett, B. M., Skjeldestad, F. E., Steinwall, M., Stoler, M. H., Wheeler, C. M., Taddeo, F. J. & 11 others, Yu, J., Lupinacci, L., Railkar, R., Marchese, R., Esser, M. T., Bryan, J., Jansen, K. U., Sings, H. L., Tamms, G. M., Saah, A. J. & Barr, E., Jul 7 2006, In : Vaccine. 24, 27-28, p. 5571-5583 13 p.

Research output: Contribution to journalArticle

303 Scopus citations

The human papillomavirus type 11 E1∧E4 protein is a transglutaminase 3 substrate and induces abnormalities of the cornified cell envelope

Brown, D. R., Kitchin, D., Qadadri, B., Neptune, N., Batteiger, T. & Ermel, A., Feb 5 2006, In : Virology. 345, 1, p. 290-298 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
2005

A longitudinal study of genital human papillomavirus infection in a cohort of closely followed adolescent women

Brown, D. B., Shew, M. L., Qadadri, B., Neptune, N., Vargas, M., Tu, W., Juliar, B. E., Breen, T. E. & Fortenberry, J. D., Jan 15 2005, In : Journal of Infectious Diseases. 191, 2, p. 182-192 11 p.

Research output: Contribution to journalArticle

317 Scopus citations

A quadrivalent vaccine prevented persistent infection and disease associated with HPV types 6, 11, 16, and 18

Villa, L. L., Costa, R. L. R., Petta, C. A., Andrade, R. P., Ault, K. A., Giuliano, A. R., Wheeler, C. M., Koutsky, L. A., Malm, C., Lehtinen, M., Skjeldestad, F. E., Olsson, S. E., Steinwall, M., Brown, D. R., Kurman, R. J., Ronnett, B. M., Stoler, M. H., Ferenczy, A., Harper, D. M., Tamms, G. M. & 10 others, Yu, J., Lupinacci, L., Railkar, R., Taddeo, F. J., Jansen, K. U., Esser, M. T., Sings, H. L., Saah, A. J., Barr, E. & Bosch, F. X., Sep 1 2005, In : Evidence-based Obstetrics and Gynecology. 7, 3, p. 160-161 2 p.

Research output: Contribution to journalShort survey

Progression from productive infection to integration and oncogenic transformation in human papillomavirus type 59-immortalized foreskin keratinocytes

Spartz, H., Lehr, E., Zhang, B., Roman, A. & Brown, D. R., May 25 2005, In : Virology. 336, 1, p. 11-25 15 p.

Research output: Contribution to journalArticle

4 Scopus citations

Prophylactic quadrivalent human papillomavirus (types 6, 11, 16, and 18) L1 virus-like particle vaccine in young women: A randomised double-blind placebo-controlled multicentre phase II efficacy trial

Villa, L. L., Costa, R. L. R., Petta, C. A., Andrade, R. P., Ault, K. A., Giuliano, A. R., Wheeler, C. M., Koutsky, L. A., Malm, C., Lehtinen, M., Skjeldestad, F. E., Olsson, S. E., Steinwall, M., Brown, D. R., Kurman, R. J., Ronnett, B. M., Stoler, M. H., Ferenczy, A., Harper, D. M., Tamms, G. M. & 9 others, Yu, J., Lupinacci, L., Railkar, R., Taddeo, F. J., Jansen, K. U., Esser, M. T., Sings, H. L., Saah, A. J. & Barr, E., May 1 2005, In : Lancet Oncology. 6, 5, p. 271-278 8 p.

Research output: Contribution to journalArticle

1052 Scopus citations
2004
10 Scopus citations

Dose-ranging studies of the safety and immunogenicity of human papillomavirus Type 11 and Type 16 virus-like particle candidate vaccines in young healthy women

Fife, K. H., Wheeler, C. M., Koutsky, L. A., Barr, E., Brown, D. R., Schiff, M. A., Kiviat, N. B., Jansen, K. U., Barber, H., Smith, J. F., Tadesse, A., Giacoletti, K., Smith, P. R., Suhr, G. & Johnson, D. A., Jul 29 2004, In : Vaccine. 22, 21-22, p. 2943-2952 10 p.

Research output: Contribution to journalArticle

104 Scopus citations

Early assessment of the efficacy of a human papillomavirus type 16 L1 virus-like particle vaccine

Brown, D. R., Fife, K. H., Wheeler, C. M., Koutsky, L. A., Lupinacci, L. M., Railkar, R., Suhr, G., Barr, E., Dicello, A., Li, W., Smith, J. F., Tadesse, A. & Jansen, K. U., Jul 29 2004, In : Vaccine. 22, 21-22, p. 2936-2942 7 p.

Research output: Contribution to journalArticle

82 Scopus citations

Infection with Human Papillomavirus Alters Expression of the Small Proline Rich Proteins 2 and 3

Lehr, E., Hohl, D., Huber, M. & Brown, D., Mar 1 2004, In : Journal of Medical Virology. 72, 3, p. 478-483 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Intracellular expression patterns of the human papillomavirus type 59 E1^E4 protein in COS cells, keratinocytes, and genital epithelium

Brown, D. R., Brown, C. R. & Lehr, E. E., Dec 3 2004, In : Intervirology. 47, 6, p. 321-327 7 p.

Research output: Contribution to journalArticle

4 Scopus citations
2003

HPV-16 vaccine prevented persistent HPV-16 infection and the development of HPV-16 related cervical neoplasia

Koutsky, L. A., Ault, K. A., Wheeler, C. M., Brown, D. R., Barr, E., Alvarez, F. B., Chiacchierini, L. M., Jansen, K. U., Wu, T. C. & Boyd, D., Mar 2003, In : Evidence-based Obstetrics and Gynecology. 5, 1, p. 42-43 2 p.

Research output: Contribution to journalShort survey

Human papillomavirus type 59 immortalized keratinocytes express late viral proteins and infectious virus after calcium stimulation

Lehr, E. E., Qadadri, B., Brown, C. R. & Brown, D. R., Sep 30 2003, In : Virology. 314, 2, p. 562-571 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

Infection with the oncogenic human papillomavirus type 59 alters protein components of the cornified cell envelope

Lehr, E. & Brown, D. R., Apr 25 2003, In : Virology. 309, 1, p. 53-60 8 p.

Research output: Contribution to journalArticle

10 Scopus citations

Poor sensitivity of polymerase chain reaction assays of genital skin swabs and urine to detect HPV 6 and 11 DNA in men

Fife, K. H., Coplan, P. M., Jansen, K. U., DiCello, A. C., Brown, D. R., Rojas, C. & Su, L., Mar 1 2003, In : Sexually transmitted diseases. 30, 3, p. 246-248 3 p.

Research output: Contribution to journalArticle

26 Scopus citations
2002

A controlled trial of a human papillomavirus type 16 vaccine

Koutsky, L. A., Ault, K. A., Wheeler, C. M., Brown, D. R., Barr, E., Alvarez, F. B., Chiacchierini, L. M. & Jansen, K. U., Nov 21 2002, In : New England Journal of Medicine. 347, 21, p. 1645-1651 7 p.

Research output: Contribution to journalArticle

1505 Scopus citations

Distribution of human papillomavirus types in cervicovaginal washings from women evaluated in a sexually transmitted diseases clinic

Brown, D. R., Legge, D. & Qadadri, B., Dec 1 2002, In : Sexually transmitted diseases. 29, 12, p. 763-768 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Expression of cytokeratin 16 in human papillomavirus type 11-infected genital epithelium

McClowry, T. L., Shors, T. & Brown, D. R., Mar 11 2002, In : Journal of Medical Virology. 66, 1, p. 96-101 6 p.

Research output: Contribution to journalArticle

6 Scopus citations

How do human papillomaviruses escape the infected keratinocyte?

Lehr, E. E. & Brown, D. R., Dec 1 2002, In : Papillomavirus Report. 13, 6, p. 181-189 9 p.

Research output: Contribution to journalReview article

2 Scopus citations

Human papillomavirus type 11 alters the transcription and expression of loricrin, the major cell envelope protein

Lehr, E., Jarnik, M. & Brown, D. R., Jan 1 2002, In : Virology. 298, 2, p. 240-247 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Low oncogenic risk anogenital HPV infection

Lacey, C. J. N., Roman, A. & Brown, D. R., Jan 1 2002, In : Papillomavirus Report. 13, 4, p. 103-109 7 p.

Research output: Contribution to journalReview article

2 Scopus citations
2001

Detection of multiple human papillomavirus types in the lower genital tract correlates with cervical dysplasia

Fife, K. H., Cramer, H. M., Schroeder, J. M. & Brown, D. R., Jul 16 2001, In : Journal of Medical Virology. 64, 4, p. 550-559 10 p.

Research output: Contribution to journalArticle

86 Scopus citations

Neutralization of human papillomavirus type 11 (HPV-11) by serum from women vaccinated with yeast-derived HPV-11 L1 virus-like particles: Correlation with competitive radioimmunoassay titer

Brown, D. R., Bryan, J. T., Schroeder, J. M., Robinson, T. S., Fife, K. H., Wheeler, C. M., Barr, E., Smith, P. R., Chiacchierini, L., DiCello, A. & Jansen, K. U., Nov 1 2001, In : Journal of Infectious Diseases. 184, 9, p. 1183-1186 4 p.

Research output: Contribution to journalArticle

89 Scopus citations

Transmission of human papillomavirus type 11 infection by desquamated cornified cells

Bryan, J. T. & Brown, D. R., Mar 1 2001, In : Virology. 281, 1, p. 35-42 8 p.

Research output: Contribution to journalArticle

33 Scopus citations

Treatment of external genital warts in men using 5% imiquimod cream applied three times a week, once daily, twice daily, or three times a day

Fife, K. H., Ferenczy, A., Douglas, J. M., Brown, D. R., Smith, M., Owens, M. L., Beutner, K., Poretz, D., Reichman, R., Sperling, M. & Spruance, S., Jan 1 2001, In : Sexually transmitted diseases. 28, 4, p. 226-231 6 p.

Research output: Contribution to journalArticle

62 Scopus citations
2000

Abnormalities of cornified cell envelopes isolated from human papillomavirus type 11-infected genital epithelium

Brown, D. R. & Bryan, J. T., May 25 2000, In : Virology. 271, 1, p. 65-70 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Association of the human papillomavirus type 11 E1/\E4 protein with cornified cell envelopes derived from infected genital epithelium

Bryan, J. T. & Brown, D. R., Nov 25 2000, In : Virology. 277, 2, p. 262-269 8 p.

Research output: Contribution to journalArticle

34 Scopus citations

Neutralization of human papillomavirus (HPV) pseudovirions: A novel and efficient approach to detect and characterize HPV neutralizing antibodies

Yeager, M. D., Aste-Amezaga, M., Brown, D. R., Martin, M. M., Shah, M. J., Cook, J. C., Christensen, N. D., Ackerson, C., Lowe, R. S., Smith, J. F., Keller, P. & Jansen, K. U., 2000, In : Virology. 278, 2, p. 570-577 8 p.

Research output: Contribution to journalArticle

49 Scopus citations

Propagation of human papillomavirus type 59 in the athymic mouse xenograft system

Bryan, J. T., Tekchandani, J., Schroeder, J. M. & Brown, D. R., Aug 2000, In : Intervirology. 43, 2, p. 112-118 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

The human papillomavirus type 11 E1/\E4 protein is phosphorylated in genital epithelium

Bryan, J. T., Han, A., Fife, K. H. & Brown, D. R., Mar 15 2000, In : Virology. 268, 2, p. 430-439 10 p.

Research output: Contribution to journalArticle

11 Scopus citations
1999

Cervical human papillomavirus deoxyribonucleic acid persists throughout pregnancy and decreases in the postpartum period

Fife, K. H., Katz, B. P., Brizendine, E. J. & Brown, D. R., Jan 1 1999, In : American Journal of Obstetrics and Gynecology. 180, 5, p. 1110-1114 5 p.

Research output: Contribution to journalArticle

46 Scopus citations

Detection of multiple human papillomavirus types in condylomata acuminata lesions from otherwise healthy and immunosuppressed patients

Brown, D. R., Schroeder, J. M., Bryan, J. T., Stoler, M. H. & Fife, K. H., Oct 7 1999, In : Journal of clinical microbiology. 37, 10, p. 3316-3322 7 p.

Research output: Contribution to journalArticle

241 Scopus citations

Human papillomavirus type 6: Classification of clinical isolates and functional analysis of E2 proteins

Kovelman, R., Bilter, G. K., Roman, A., Brown, D. R. & Barbosa, M. S., Jan 1 1999, In : Journal of General Virology. 80, 9, p. 2445-2451 7 p.

Research output: Contribution to journalArticle

Open Access
13 Scopus citations

Nucleotide sequence and characterization of human papillomavirus type 83, a novel genital papillomavirus

Brown, D. R., McClowry, T. L., Woods, K. & Fife, K. H., Jul 20 1999, In : Virology. 260, 1, p. 165-172 8 p.

Research output: Contribution to journalArticle

22 Scopus citations
1998

A human papillomavirus related to human papillomavirus MM7/LVX82 produces distinct histological abnormalities in human foreskin implants grown as athymic mouse xenografts

Brown, D. R., McClowry, T. L., Bryan, J. T., Stoler, M., Schroeder-Diedrich, J. M. & Fife, K. H., Sep 15 1998, In : Virology. 249, 1, p. 150-159 10 p.

Research output: Contribution to journalArticle

17 Scopus citations

Expression of the human papillomavirus type 11 E5A protein from the E1@?E4,E5 transcript

Brown, D. R., McClowry, T. L., Sidner, R. A., Fife, K. H. & Bryan, J. T., Aug 1 1998, In : Intervirology. 41, 1, p. 47-54 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

High-grade dysplasia in genital warts from two patients infected with the human immunodeficiency virus

Bryan, J. T., Stoler, M. H., Tyring, S. K., McClowry, T., Fife, K. H. & Brown, D. R., Jan 1 1998, In : Journal of Medical Virology. 54, 1, p. 69-73 5 p.

Research output: Contribution to journalArticle

13 Scopus citations