David Basile

  • 3640 Citations
  • 28 h-Index
1993 …2019
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Publications 1993 2019

1993
30 Citations (Scopus)
Fibroblast Growth Factor 2
Suramin
Growth
Fibroblast Growth Factor Receptors
DNA
fibroblast growth factor 2
Fibroblast Growth Factor 2
Growth
1994
25 Citations (Scopus)

Basic fibroblast growth factor receptor in the rat adrenal cortex: Effects of suramin and unilateral adrenalectomy on receptor numbers

Basile, D. P. & Holzwarth, M. A., Jun 1994, In : Endocrinology. 134, 6, p. 2482-2489 8 p.

Research output: Contribution to journalArticle

Suramin
Fibroblast Growth Factor Receptors
Adrenal Cortex
Adrenalectomy
Fibroblast Growth Factor 2
1996
110 Citations (Scopus)

Increased transforming growth factor-ßl expression in regenerating rat renal tubules following ischémie injury

Basile, D. P., Rovak, J. M., Martin, D. R. & Hammerman, M. R., Dec 1 1996, In : American Journal of Physiology. 270, 3 PART 2, p. F500-F509

Research output: Contribution to journalArticle

Transforming Growth Factors
Kidney
Wounds and Injuries
Ischemia
Messenger RNA
1997
118 Citations (Scopus)

Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury

Basile, D. P., Liapis, H. & Hammerman, M. R., May 1 1997, In : American Journal of Physiology - Renal Physiology. 272, 5 41-5, p. F640-F647

Research output: Contribution to journalArticle

Kidney
Wounds and Injuries
Messenger RNA
bcl-2-Associated X Protein
Nephrons
1998
77 Citations (Scopus)

Extracellular matrix-related genes in kidney after ischemic injury: Potential role for TGF-β in repair

Basile, D. P., Martin, D. R. & Hammerman, M. R., Dec 1 1998, In : American Journal of Physiology - Renal Physiology. 275, 6 44-6, p. F894-F903

Research output: Contribution to journalArticle

Extracellular Matrix
Plasminogen Activator Inhibitor 1
Kidney
Metalloproteases
Collagen
14 Citations (Scopus)

TGF-β in renal development and renal growth

Basile, D. P. & Hammerman, M. R., Mar 1 1998, In : Mineral and Electrolyte Metabolism. 24, 2-3, p. 144-148 5 p.

Research output: Contribution to journalShort survey

Growth and Development
Intercellular Signaling Peptides and Proteins
Kidney
Regeneration
Repair
6 Citations (Scopus)

The human plasminogen activator inhibitor type I gene promoter targets to kidney

Emert, M. P., Sorenson, C. M., Basile, D. P., Rogers, J. G., Hammerman, M. R. & Billadello, J. J., Feb 1 1998, In : American Journal of Physiology - Renal Physiology. 274, 2 43-2, p. F405-F412

Research output: Contribution to journalArticle

Plasminogen Inactivators
Plasminogen Activator Inhibitor 1
Transforming Growth Factors
Transgenes
Kidney
1999
89 Citations (Scopus)
Kidney Diseases
Transforming Growth Factor beta
Kidney
Thrombospondin 1
Wounds and Injuries
1 Citation (Scopus)

Toward an effective gene therapy in renal disease

Basile, D. P., Jan 1 1999, In : Kidney international. 55, 2, p. 740-741 2 p.

Research output: Contribution to journalEditorial

Transforming Growth Factor beta
Genetic Therapy
Kidney
2000
3 Citations (Scopus)

Is angiotensin II's role in fibrosis as easy as PAI(-1)?

Basile, D. P., Jan 1 2000, In : Kidney international. 58, 1, p. 460-461 2 p.

Research output: Contribution to journalEditorial

Plasminogen Activator Inhibitor 1
Renin-Angiotensin System
Chronic Renal Insufficiency
Angiotensin II
Fibrosis
2001
475 Citations (Scopus)

Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function

Basile, D. P., Donohoe, D., Roethe, K. & Osborn, J. L., Dec 19 2001, In : American Journal of Physiology - Renal Physiology. 281, 5 50-5, p. F887-F899

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Wounds and Injuries
Fibrosis
Ischemia
15 Citations (Scopus)

Transforming growth factor-β as a target for treatment in diabetic nephropathy

Basile, D. P., Jan 1 2001, In : American Journal of Kidney Diseases. 38, 4, p. 887-890 4 p.

Research output: Contribution to journalShort survey

Diabetic Nephropathies
Transforming Growth Factor beta
Type 2 Diabetes Mellitus
Signal Transduction
Fibrosis
2003
110 Citations (Scopus)

Chronic renal hypoxia after acute ischemic injury: Effects of L-arginine on hypoxia and secondary damage

Basile, D. P., Donohoe, D. L., Roethe, K. & Mattson, D. L., Feb 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 2 53-2, p. F338-F348

Research output: Contribution to journalArticle

Acute Kidney Injury
Arginine
Kidney
Wounds and Injuries
Reperfusion Injury
2004
101 Citations (Scopus)

Angiostatin and matrix metalloprotease expression following ischemic acute renal failure

Basile, D. P., Fredrich, K., Weihrauch, D., Hattan, N. & Chilian, W. M., May 1 2004, In : American Journal of Physiology - Renal Physiology. 286, 5 55-5, p. F893-F902

Research output: Contribution to journalArticle

Angiostatins
Metalloproteases
Acute Kidney Injury
Kidney
Plasminogen
144 Citations (Scopus)
Acute Kidney Injury
Causality
Kidney
Transplants
Wounds and Injuries
39 Citations (Scopus)

Resistance to ischemic acute renal failure in the Brown Norway rat: A new model to study cytoprotection

Basile, D. P., Donohoe, D., Cao, X. & Van Why, S. K., Jun 2004, In : Kidney international. 65, 6, p. 2201-2211 11 p.

Research output: Contribution to journalArticle

Cytoprotection
Acute Kidney Injury
Sprague Dawley Rats
Kidney
Ischemia
2005
14 Citations (Scopus)

Enhanced skeletal muscle arteriolar reactivity to ANG II after recovery from ischemic acute renal failure

Basile, D. P., Donohoe, D. L., Phillips, S. A. & Frisbee, J. C., Dec 1 2005, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 289, 6 58-6, p. R1770-R1776

Research output: Contribution to journalArticle

Acute Kidney Injury
Skeletal Muscle
Kidney
Arterioles
Norepinephrine
76 Citations (Scopus)

Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure

Basile, D. P., Fredrich, K., Alausa, M., Vio, C. P., Liang, M., Rieder, M. R., Greene, A. S. & Cowley, A. W., May 1 2005, In : American Journal of Physiology - Renal Physiology. 288, 5 57-5, p. F953-F963

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Gene Expression
Genes
Reperfusion Injury
20 Citations (Scopus)

Transcriptome analysis and kidney research: Toward systems biology

Liang, M., Cowley, A. W., Hessner, M. J., Lazar, J., Basile, D. P. & Pietrusz, J. L., Jun 2005, In : Kidney international. 67, 6, p. 2114-2122 9 p.

Research output: Contribution to journalArticle

Systems Biology
Gene Expression Profiling
Kidney
Research
Oligonucleotide Array Sequence Analysis
74 Citations (Scopus)
Transforming Growth Factors
Acute Kidney Injury
Kidney
Wounds and Injuries
Growth Factor Receptors
2006
22 Citations (Scopus)

Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis

Gama, V., Yoshida, T., Gomez, J. A., Basile, D. P., Mayo, L. D., Haas, A. L. & Matsuyama, S., Feb 15 2006, In : Experimental Cell Research. 312, 4, p. 488-499 12 p.

Research output: Contribution to journalArticle

Ubiquitin
Apoptosis
Pharmaceutical Preparations
DNA Repair
Ubiquitinated Proteins
2007
6 Citations (Scopus)

Angiostatin does not contribute to skeletal muscle microvascular rarefaction with low nitric oxide bioavailability

Frisbee, J. C., Samora, J. B. & Basile, D. P., Feb 1 2007, In : Microcirculation. 14, 2, p. 145-153 9 p.

Research output: Contribution to journalArticle

Angiostatins
NG-Nitroarginine Methyl Ester
Biological Availability
Nitric Oxide
Skeletal Muscle
19 Citations (Scopus)

Leptin regulates gallbladder genes related to absorption and secretion

Swartz-Basile, D. A., Lu, D., Basile, D. P., Graewin, S. J., Al-Azzawi, H., Kiely, J. M., Mathur, A., Yancey, K. & Pitt, H. A., Jul 1 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 293, 1, p. G84-G90

Research output: Contribution to journalArticle

Leptin
Gallbladder
Genes
Bile
Sodium
7 Citations (Scopus)

Novel approaches in the investigation of acute kidney injury

Basile, D. P., Jan 1 2007, In : Journal of the American Society of Nephrology. 18, 1, p. 7-9 3 p.

Research output: Contribution to journalEditorial

Acute Disease
Genomics
Reperfusion Injury
Bone Marrow Transplantation
Acute Kidney Injury
73 Citations (Scopus)

Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium

Spurgeon-Pechman, K. R., Donohoe, D. L., Mattson, D. L., Lund, H., James, L. & Basile, D. P., Jul 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 1, p. F269-F278

Research output: Contribution to journalArticle

Renal Hypertension
Acute Kidney Injury
Sodium
Diet
Reperfusion Injury
285 Citations (Scopus)

The endothelial cell in ischemic acute kidney injury: Implications for acute and chronic function

Basile, D. P., Jul 1 2007, In : Kidney international. 72, 2, p. 151-156 6 p.

Research output: Contribution to journalShort survey

Acute Kidney Injury
Blood Vessels
Endothelial Cells
Kidney
Reperfusion
2008
4 Citations (Scopus)
Receptor Cross-Talk
Cecum
Toll-Like Receptors
Acute Kidney Injury
Sepsis
7 Citations (Scopus)

Challenges of targeting vascular stability in acute kidney injury

Basile, D. P., Aug 2008, In : Kidney international. 74, 3, p. 257-258 2 p.

Research output: Contribution to journalComment/debate

Acute Kidney Injury
Blood Vessels
Folic Acid
Angiopoietin-1
Kidney
51 Citations (Scopus)

Immune suppression blocks sodium-sensitive hypertension following recovery from ischemic acute renal failure

Pechman, K. R., Basile, D. P., Lund, H. & Mattson, D. L., Apr 1 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 4, p. R1234-R1239

Research output: Contribution to journalArticle

Acute Kidney Injury
Mycophenolic Acid
Sodium
Reperfusion
Hypertension
109 Citations (Scopus)

Renal ischemia reperfusion inhibits VEGF expression and induces ADAMTS-1, a novel VEGF inhibitor

Basile, D. P., Fredrich, K., Chelladurai, B., Leonard, E. C. & Parrish, A. R., Apr 1 2008, In : American Journal of Physiology - Renal Physiology. 294, 4, p. F928-F936

Research output: Contribution to journalArticle

Thrombospondin 1
Disintegrins
Metalloproteases
Vascular Endothelial Growth Factor A
Reperfusion
99 Citations (Scopus)

VEGF-121 preserves renal microvessel structure and ameliorates secondary renal disease following acute kidney injury

Leonard, E. C., Friedrich, J. L. & Basile, D. P., Dec 1 2008, In : American Journal of Physiology - Renal Physiology. 295, 6, p. F1648-F1657

Research output: Contribution to journalArticle

Microvessels
Acute Kidney Injury
Vascular Endothelial Growth Factor A
Sodium
Kidney
2009
22 Citations (Scopus)

Expression of the RNA-stabilizing protein HuR in ischemia-reperfusion injury of rat kidney

Ayupova, D. A., Singh, M., Leonard, E. C., Basile, D. P. & Lee, B. S., Jul 1 2009, In : American Journal of Physiology - Renal Physiology. 297, 1, p. F95-F105

Research output: Contribution to journalArticle

Reperfusion Injury
RNA
Kidney
Antigens
Proteins
55 Citations (Scopus)
Natriuresis
Reperfusion Injury
Hemodynamics
Sodium
Hypertension
2010
13 Citations (Scopus)

Increased ANG II sensitivity following recovery from acute kidney injury: Role of oxidant stress in skeletal muscle resistance arteries

Phillips, S. A., Pechman, K. R., Leonard, E. C., Friedrich, J. L., Bian, J. T., Beal, A. G. & Basile, D. P., Jun 1 2010, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 298, 6, p. R1682-R1691

Research output: Contribution to journalArticle

Acute Kidney Injury
Oxidants
Skeletal Muscle
Arteries
Blood Vessels
2011

A GAP in our knowledge of vascular signaling in acute kidney injury

Basile, D. P., Aug 1 2011, In : Kidney international. 80, 3, p. 233-235 3 p.

Research output: Contribution to journalComment/debate

GTP Phosphohydrolases
Reperfusion Injury
Acute Kidney Injury
Blood Vessels
G-Protein-Coupled Receptors
177 Citations (Scopus)

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury

Basile, D. P., Friedrich, J. L., Spahic, J., Knipe, N., Mang, H., Leonard, E. C., Changizi-Ashtiyani, S., Bacallao, R. L., Molitoris, B. A. & Sutton, T. A., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3, p. F721-F733

Research output: Contribution to journalArticle

Acute Kidney Injury
Blood Vessels
Endothelial Cells
Vascular Endothelial Growth Factor A
Bromodeoxyuridine
13 Citations (Scopus)

Sodium reabsorption in the thick ascending limb in relation to blood pressure: A clinical perspective

Jung, J., Basile, D. P. & Pratt, J. H., May 1 2011, In : Hypertension. 57, 5, p. 873-879 7 p.

Research output: Contribution to journalReview article

Loop of Henle
Extremities
Sodium
Blood Pressure
Hypertension
18 Citations (Scopus)

Vasodilatation in the rat dorsal hindpaw induced by activation of sensory neurons is reduced by paclitaxel

Gracias, N. G., Cummins, T. R., Kelley, M. R., Basile, D. P., Iqbal, T. & Vasko, M. R., Jan 1 2011, In : NeuroToxicology. 32, 1, p. 140-149 10 p.

Research output: Contribution to journalArticle

Sensory Receptor Cells
Paclitaxel
Vasodilation
Neurons
Rats
2012
5 Citations (Scopus)
ADAM Proteins
Tissue Inhibitor of Metalloproteinase-3
Pericytes
Kidney Diseases
Blood Vessels
28 Citations (Scopus)

Distinct effects on long-term function of injured and contralateral kidneys following unilateral renal ischemia-reperfusion

Basile, D. P., Leonard, E. C., Tonade, D., Friedrich, J. L. & Goenka, S., Mar 1 2012, In : American Journal of Physiology - Renal Physiology. 302, 5, p. F625-F635

Research output: Contribution to journalArticle

Reperfusion
Ischemia
Kidney
Acute Kidney Injury
Chronic Renal Insufficiency
15 Citations (Scopus)

Low Proliferative Potential and Impaired Angiogenesis of Cultured Rat Kidney Endothelial Cells

Basile, D. P., Zeng, P., Friedrich, J. L., Leonard, E. C. & Yoder, M. C., Oct 1 2012, In : Microcirculation. 19, 7, p. 598-609 12 p.

Research output: Contribution to journalArticle

Endothelial Cells
Kidney
Growth
Vascular Endothelial Growth Factor Receptor
Human Umbilical Vein Endothelial Cells
314 Citations (Scopus)

Pathophysiology of acute kidney injury

Basile, D. P., Anderson, M. D. & Sutton, T. A., Apr 1 2012, In : Comprehensive Physiology. 2, 2, p. 1303-1353 51 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Renal Circulation
Wounds and Injuries
Glomerular Filtration Rate
Chronic Renal Insufficiency
46 Citations (Scopus)

Persistent oxidative stress following renal ischemia-reperfusion injury increases ANG II hemodynamic and fibrotic activity

Basile, D. P., Leonard, E. C., Beal, A. G., Schleuter, D. & Friedrich, J., Jun 1 2012, In : American Journal of Physiology - Renal Physiology. 302, 11, p. F1494-F1502

Research output: Contribution to journalArticle

Reperfusion Injury
Oxidative Stress
Acute Kidney Injury
Hemodynamics
Kidney
13 Citations (Scopus)

Soluble thrombomodulin reduces inflammation and prevents microalbuminuria induced by chronic endothelial activation in transgenic mice

Rajashekhar, G., Gupta, A., Marin, A., Friedrich, J., Willuweit, A., Berg, D. T., Cramer, M. S., Sandusky, G. E., Sutton, T. A., Basile, D. P., Grinnell, B. W. & Clauss, M., Mar 1 2012, In : American Journal of Physiology - Renal Physiology. 302, 6, p. F703-F712

Research output: Contribution to journalArticle

Thrombomodulin
Transgenic Mice
Inflammation
Chronic Renal Insufficiency
Chemokines
2013
31 Citations (Scopus)

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

Research
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Kidney
Kidney Diseases
Animal Models
21 Citations (Scopus)

A method to facilitate and monitor expression of exogenous genes in the rat kidney using plasmid and viral vectors

Corridon, P. R., Rhodes, G. J., Leonard, E. C., Basile, D. P., Gattone, V. H., Bacallao, R. L. & Atkinson, S. J., Jun 10 2013, In : American Journal of Physiology - Renal Physiology. 304, 9, p. F1217-F1229

Research output: Contribution to journalArticle

Plasmids
Kidney
Gene Expression
Transgenes
Adenoviridae
9 Citations (Scopus)

Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats

Basile, D. P., Dwinell, M. R., Wang, S. J., Shames, B. D., Donohoe, D. L., Chen, S., Sreedharan, R. & Van Why, S. K., Feb 2013, In : Kidney international. 83, 2, p. 242-250 9 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Acute Kidney Injury
Chromosomes
Alleles
Reperfusion
217 Citations (Scopus)
Respiratory Physiological Phenomena
Students
Kidney
Curriculum
Physiological Phenomena
1 Citation (Scopus)
EphB4 Receptor
Ephrin-B2
Pericytes
Acute Kidney Injury
Kidney