David Basile

  • 3640 Citations
  • 28 h-Index
1993 …2019
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Publications 1993 2019

5 Citations (Scopus)
ADAM Proteins
Tissue Inhibitor of Metalloproteinase-3
Pericytes
Kidney Diseases
Blood Vessels

A GAP in our knowledge of vascular signaling in acute kidney injury

Basile, D. P., Aug 1 2011, In : Kidney international. 80, 3, p. 233-235 3 p.

Research output: Contribution to journalComment/debate

GTP Phosphohydrolases
Reperfusion Injury
Acute Kidney Injury
Blood Vessels
G-Protein-Coupled Receptors
31 Citations (Scopus)

AKI: A path forward

Bonventre, J. V., Basile, D., Liu, K. D., McKay, D., Molitoris, B. A., Nath, K. A., Nickolas, T. L., Okusa, M. D., Palevsky, P. M., Schnellmann, R., Rys-Sikora, K., Kimmel, P. L. & Star, R. A., Sep 16 2013, In : Clinical Journal of the American Society of Nephrology. 8, 9, p. 1606-1608 3 p.

Research output: Contribution to journalArticle

Research
National Institute of Diabetes and Digestive and Kidney Diseases (U.S.)
Kidney
Kidney Diseases
Animal Models
21 Citations (Scopus)

A method to facilitate and monitor expression of exogenous genes in the rat kidney using plasmid and viral vectors

Corridon, P. R., Rhodes, G. J., Leonard, E. C., Basile, D. P., Gattone, V. H., Bacallao, R. L. & Atkinson, S. J., Jun 10 2013, In : American Journal of Physiology - Renal Physiology. 304, 9, p. F1217-F1229

Research output: Contribution to journalArticle

Plasmids
Kidney
Gene Expression
Transgenes
Adenoviridae
4 Citations (Scopus)
Receptor Cross-Talk
Cecum
Toll-Like Receptors
Acute Kidney Injury
Sepsis
101 Citations (Scopus)

Angiostatin and matrix metalloprotease expression following ischemic acute renal failure

Basile, D. P., Fredrich, K., Weihrauch, D., Hattan, N. & Chilian, W. M., May 1 2004, In : American Journal of Physiology - Renal Physiology. 286, 5 55-5, p. F893-F902

Research output: Contribution to journalArticle

Angiostatins
Metalloproteases
Acute Kidney Injury
Kidney
Plasminogen
6 Citations (Scopus)

Angiostatin does not contribute to skeletal muscle microvascular rarefaction with low nitric oxide bioavailability

Frisbee, J. C., Samora, J. B. & Basile, D. P., Feb 1 2007, In : Microcirculation. 14, 2, p. 145-153 9 p.

Research output: Contribution to journalArticle

Angiostatins
NG-Nitroarginine Methyl Ester
Biological Availability
Nitric Oxide
Skeletal Muscle
30 Citations (Scopus)
Fibroblast Growth Factor 2
Suramin
Growth
Fibroblast Growth Factor Receptors
DNA
fibroblast growth factor 2
Fibroblast Growth Factor 2
Growth
25 Citations (Scopus)

Basic fibroblast growth factor receptor in the rat adrenal cortex: Effects of suramin and unilateral adrenalectomy on receptor numbers

Basile, D. P. & Holzwarth, M. A., Jun 1994, In : Endocrinology. 134, 6, p. 2482-2489 8 p.

Research output: Contribution to journalArticle

Suramin
Fibroblast Growth Factor Receptors
Adrenal Cortex
Adrenalectomy
Fibroblast Growth Factor 2
1 Citation (Scopus)

Calcium channel Orai1 promotes lymphocyte IL-17 expression and progressive kidney injury

Mehrotra, P., Sturek, M., Neyra, J. A. & Basile, D. P., Nov 1 2019, In : Journal of Clinical Investigation. 129, 11, p. 4951-4961 11 p.

Research output: Contribution to journalArticle

Open Access
Interleukin-17
Calcium Channels
Lymphocytes
Kidney
Wounds and Injuries
7 Citations (Scopus)

Challenges of targeting vascular stability in acute kidney injury

Basile, D. P., Aug 2008, In : Kidney international. 74, 3, p. 257-258 2 p.

Research output: Contribution to journalComment/debate

Acute Kidney Injury
Blood Vessels
Folic Acid
Angiopoietin-1
Kidney
9 Citations (Scopus)

Chromosome substitution modulates resistance to ischemia reperfusion injury in Brown Norway rats

Basile, D. P., Dwinell, M. R., Wang, S. J., Shames, B. D., Donohoe, D. L., Chen, S., Sreedharan, R. & Van Why, S. K., Feb 2013, In : Kidney international. 83, 2, p. 242-250 9 p.

Research output: Contribution to journalArticle

Reperfusion Injury
Acute Kidney Injury
Chromosomes
Alleles
Reperfusion
110 Citations (Scopus)

Chronic renal hypoxia after acute ischemic injury: Effects of L-arginine on hypoxia and secondary damage

Basile, D. P., Donohoe, D. L., Roethe, K. & Mattson, D. L., Feb 1 2003, In : American Journal of Physiology - Renal Physiology. 284, 2 53-2, p. F338-F348

Research output: Contribution to journalArticle

Acute Kidney Injury
Arginine
Kidney
Wounds and Injuries
Reperfusion Injury
121 Citations (Scopus)

Circulating and Tissue Resident Endothelial Progenitor Cells

Basile, D. P. & Yoder, M. C., Jan 1 2014, In : Journal of cellular physiology. 229, 1, p. 10-16 7 p.

Research output: Contribution to journalArticle

Endothelial cells
Tissue
Terminology
Tunica Intima
Repair
28 Citations (Scopus)

Distinct effects on long-term function of injured and contralateral kidneys following unilateral renal ischemia-reperfusion

Basile, D. P., Leonard, E. C., Tonade, D., Friedrich, J. L. & Goenka, S., Mar 1 2012, In : American Journal of Physiology - Renal Physiology. 302, 5, p. F625-F635

Research output: Contribution to journalArticle

Reperfusion
Ischemia
Kidney
Acute Kidney Injury
Chronic Renal Insufficiency
4 Citations (Scopus)

Effect of renal shock wave lithotripsy on the development of metabolic syndrome in a juvenile swine model: A pilot study

Handa, R. K., Liu, Z., Connors, B. A., Alloosh, M., Basile, D. P., Tune, J. D., Sturek, M., Evan, A. P. & Lingeman, J. E., Apr 1 2015, In : Journal of Urology. 193, 4, p. 1409-1416 8 p.

Research output: Contribution to journalArticle

Lithotripsy
Swine
Kidney
Atherogenic Diet
Glucose Tolerance Test
14 Citations (Scopus)

Endothelial colony-forming cells ameliorate endothelial dysfunction via secreted factors following ischemia-reperfusion injury

Collett, J. A., Mehrotra, P., Crone, A., Christopher, W. S., Yoder, M. & Basile, D., May 15 2017, In : American Journal of Physiology - Renal Physiology. 312, 5, p. F897-F907

Research output: Contribution to journalArticle

Reperfusion Injury
Endothelial Cells
Kidney
Lung
Ischemia
9 Citations (Scopus)
Acute Kidney Injury
Blood Vessels
Chronic Renal Insufficiency
Perfusion
Kidney
14 Citations (Scopus)

Enhanced skeletal muscle arteriolar reactivity to ANG II after recovery from ischemic acute renal failure

Basile, D. P., Donohoe, D. L., Phillips, S. A. & Frisbee, J. C., Dec 1 2005, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 289, 6 58-6, p. R1770-R1776

Research output: Contribution to journalArticle

Acute Kidney Injury
Skeletal Muscle
Kidney
Arterioles
Norepinephrine
1 Citation (Scopus)

Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection

Kolb, A. L., Corridon, P. R., Zhang, S., Xu, W., Witzmann, F., Collett, J. A., Rhodes, G. J., Winfree, S., Bready, D., Pfeffenberger, Z. J., Pomerantz, J. M., Hato, T., Nagami, G. T., Molitoris, B., Basile, D., Atkinson, S. J. & Bacallao, R., Apr 1 2018, In : Journal of the American Society of Nephrology. 29, 4, p. 1154-1164 11 p.

Research output: Contribution to journalArticle

Isocitrate Dehydrogenase
Ischemic Preconditioning
Mitochondria
Cytoprotection
Wounds and Injuries
118 Citations (Scopus)

Expression of bcl-2 and bax in regenerating rat renal tubules following ischemic injury

Basile, D. P., Liapis, H. & Hammerman, M. R., May 1 1997, In : American Journal of Physiology - Renal Physiology. 272, 5 41-5, p. F640-F647

Research output: Contribution to journalArticle

Kidney
Wounds and Injuries
Messenger RNA
bcl-2-Associated X Protein
Nephrons
22 Citations (Scopus)

Expression of the RNA-stabilizing protein HuR in ischemia-reperfusion injury of rat kidney

Ayupova, D. A., Singh, M., Leonard, E. C., Basile, D. P. & Lee, B. S., Jul 1 2009, In : American Journal of Physiology - Renal Physiology. 297, 1, p. F95-F105

Research output: Contribution to journalArticle

Reperfusion Injury
RNA
Kidney
Antigens
Proteins
77 Citations (Scopus)

Extracellular matrix-related genes in kidney after ischemic injury: Potential role for TGF-β in repair

Basile, D. P., Martin, D. R. & Hammerman, M. R., Dec 1 1998, In : American Journal of Physiology - Renal Physiology. 275, 6 44-6, p. F894-F903

Research output: Contribution to journalArticle

Extracellular Matrix
Plasminogen Activator Inhibitor 1
Kidney
Metalloproteases
Collagen
217 Citations (Scopus)
Respiratory Physiological Phenomena
Students
Kidney
Curriculum
Physiological Phenomena
1 Citation (Scopus)
EphB4 Receptor
Ephrin-B2
Pericytes
Acute Kidney Injury
Kidney
8 Citations (Scopus)

Human adipose stromal cell therapy improves survival and reduces renal inflammation and capillary rarefaction in acute kidney injury

Collett, J. A., Traktuev, D., Mehrotra, P., Crone, A., Merfeld-Clauss, S., March, K. L. & Basile, D., 2017, (Accepted/In press) In : Journal of Cellular and Molecular Medicine.

Research output: Contribution to journalArticle

Stromal Cells
Cell- and Tissue-Based Therapy
Acute Kidney Injury
Inflammation
Kidney
7 Citations (Scopus)

Hydrodynamic isotonic fluid delivery ameliorates moderate-to-severe ischemia-reperfusion injury in rat kidneys

Collett, J. A., Corridon, P. R., Mehrotra, P., Kolb, A. L., Rhodes, G. J., Miller, C. A., Molitoris, B. A., Pennington, J. G., Sandoval, R. M., Atkinson, S. J., Campos-Bilderback, S. B., Basile, D. P. & Bacallao, R. L., Jul 2017, In : Journal of the American Society of Nephrology. 28, 7, p. 2081-2092 12 p.

Research output: Contribution to journalArticle

Hydrodynamics
Reperfusion Injury
Kidney
Renal Veins
Wounds and Injuries
76 Citations (Scopus)

Identification of persistently altered gene expression in the kidney after functional recovery from ischemic acute renal failure

Basile, D. P., Fredrich, K., Alausa, M., Vio, C. P., Liang, M., Rieder, M. R., Greene, A. S. & Cowley, A. W., May 1 2005, In : American Journal of Physiology - Renal Physiology. 288, 5 57-5, p. F953-F963

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Gene Expression
Genes
Reperfusion Injury
20 Citations (Scopus)

IL-17 mediates neutrophil infiltration and renal fibrosis following recovery from ischemia reperfusion: Compensatory role of natural killer cells in athymic rats

Mehrotra, P., Collett, J. A., McKinney, S. D., Stevens, J., Ivancic, C. M. & Basile, D., Mar 1 2017, In : American Journal of Physiology - Renal Physiology. 312, 3, p. F385-F397

Research output: Contribution to journalArticle

Nude Rats
Interleukin-17
Neutrophil Infiltration
Natural Killer Cells
Reperfusion
51 Citations (Scopus)

Immune suppression blocks sodium-sensitive hypertension following recovery from ischemic acute renal failure

Pechman, K. R., Basile, D. P., Lund, H. & Mattson, D. L., Apr 1 2008, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 294, 4, p. R1234-R1239

Research output: Contribution to journalArticle

Acute Kidney Injury
Mycophenolic Acid
Sodium
Reperfusion
Hypertension
177 Citations (Scopus)

Impaired endothelial proliferation and mesenchymal transition contribute to vascular rarefaction following acute kidney injury

Basile, D. P., Friedrich, J. L., Spahic, J., Knipe, N., Mang, H., Leonard, E. C., Changizi-Ashtiyani, S., Bacallao, R. L., Molitoris, B. A. & Sutton, T. A., Mar 1 2011, In : American Journal of Physiology - Renal Physiology. 300, 3, p. F721-F733

Research output: Contribution to journalArticle

Acute Kidney Injury
Blood Vessels
Endothelial Cells
Vascular Endothelial Growth Factor A
Bromodeoxyuridine
13 Citations (Scopus)

Increased ANG II sensitivity following recovery from acute kidney injury: Role of oxidant stress in skeletal muscle resistance arteries

Phillips, S. A., Pechman, K. R., Leonard, E. C., Friedrich, J. L., Bian, J. T., Beal, A. G. & Basile, D. P., Jun 1 2010, In : American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 298, 6, p. R1682-R1691

Research output: Contribution to journalArticle

Acute Kidney Injury
Oxidants
Skeletal Muscle
Arteries
Blood Vessels
110 Citations (Scopus)

Increased transforming growth factor-ßl expression in regenerating rat renal tubules following ischémie injury

Basile, D. P., Rovak, J. M., Martin, D. R. & Hammerman, M. R., Dec 1 1996, In : American Journal of Physiology. 270, 3 PART 2, p. F500-F509

Research output: Contribution to journalArticle

Transforming Growth Factors
Kidney
Wounds and Injuries
Ischemia
Messenger RNA
22 Citations (Scopus)

Involvement of the ubiquitin pathway in decreasing Ku70 levels in response to drug-induced apoptosis

Gama, V., Yoshida, T., Gomez, J. A., Basile, D. P., Mayo, L. D., Haas, A. L. & Matsuyama, S., Feb 15 2006, In : Experimental Cell Research. 312, 4, p. 488-499 12 p.

Research output: Contribution to journalArticle

Ubiquitin
Apoptosis
Pharmaceutical Preparations
DNA Repair
Ubiquitinated Proteins
3 Citations (Scopus)

Is angiotensin II's role in fibrosis as easy as PAI(-1)?

Basile, D. P., Jan 1 2000, In : Kidney international. 58, 1, p. 460-461 2 p.

Research output: Contribution to journalEditorial

Plasminogen Activator Inhibitor 1
Renin-Angiotensin System
Chronic Renal Insufficiency
Angiotensin II
Fibrosis
19 Citations (Scopus)

Leptin regulates gallbladder genes related to absorption and secretion

Swartz-Basile, D. A., Lu, D., Basile, D. P., Graewin, S. J., Al-Azzawi, H., Kiely, J. M., Mathur, A., Yancey, K. & Pitt, H. A., Jul 1 2007, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 293, 1, p. G84-G90

Research output: Contribution to journalArticle

Leptin
Gallbladder
Genes
Bile
Sodium
15 Citations (Scopus)

Low Proliferative Potential and Impaired Angiogenesis of Cultured Rat Kidney Endothelial Cells

Basile, D. P., Zeng, P., Friedrich, J. L., Leonard, E. C. & Yoder, M. C., Oct 1 2012, In : Microcirculation. 19, 7, p. 598-609 12 p.

Research output: Contribution to journalArticle

Endothelial Cells
Kidney
Growth
Vascular Endothelial Growth Factor Receptor
Human Umbilical Vein Endothelial Cells
7 Citations (Scopus)

Novel approaches in the investigation of acute kidney injury

Basile, D. P., Jan 1 2007, In : Journal of the American Society of Nephrology. 18, 1, p. 7-9 3 p.

Research output: Contribution to journalEditorial

Acute Disease
Genomics
Reperfusion Injury
Bone Marrow Transplantation
Acute Kidney Injury

Pathogenesis of acute kidney injury

Basile, D., Sreedharan, R. & van Why, S. K., Jan 1 2015, Pediatric Nephrology, Seventh Edition. Springer Berlin Heidelberg, p. 2101-2138 38 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Acute Kidney Injury
Kidney
Terminology
Perfusion
Urine
314 Citations (Scopus)

Pathophysiology of acute kidney injury

Basile, D. P., Anderson, M. D. & Sutton, T. A., Apr 1 2012, In : Comprehensive Physiology. 2, 2, p. 1303-1353 51 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Renal Circulation
Wounds and Injuries
Glomerular Filtration Rate
Chronic Renal Insufficiency
46 Citations (Scopus)

Persistent oxidative stress following renal ischemia-reperfusion injury increases ANG II hemodynamic and fibrotic activity

Basile, D. P., Leonard, E. C., Beal, A. G., Schleuter, D. & Friedrich, J., Jun 1 2012, In : American Journal of Physiology - Renal Physiology. 302, 11, p. F1494-F1502

Research output: Contribution to journalArticle

Reperfusion Injury
Oxidative Stress
Acute Kidney Injury
Hemodynamics
Kidney
126 Citations (Scopus)

Progression after AKI: UnderstanDing maladaptive repair processes to predict and identify therapeutic treatments

Basile, D., Bonventre, J. V., Mehta, R., Nangaku, M., Unwin, R., Rosner, M. H., Kellum, J. A. & Ronco, C., Mar 1 2016, In : Journal of the American Society of Nephrology. 27, 3, p. 687-697 11 p.

Research output: Contribution to journalArticle

Acute Kidney Injury
Nephrology
Focus Groups
Terminology
Dialysis
144 Citations (Scopus)
Acute Kidney Injury
Causality
Kidney
Transplants
Wounds and Injuries
73 Citations (Scopus)

Recovery from acute renal failure predisposes hypertension and secondary renal disease in response to elevated sodium

Spurgeon-Pechman, K. R., Donohoe, D. L., Mattson, D. L., Lund, H., James, L. & Basile, D. P., Jul 1 2007, In : American Journal of Physiology - Renal Physiology. 293, 1, p. F269-F278

Research output: Contribution to journalArticle

Renal Hypertension
Acute Kidney Injury
Sodium
Diet
Reperfusion Injury
55 Citations (Scopus)
Natriuresis
Reperfusion Injury
Hemodynamics
Sodium
Hypertension
56 Citations (Scopus)
Reperfusion Injury
Blood Vessels
Renal Circulation
Kidney
Acute Kidney Injury
109 Citations (Scopus)

Renal ischemia reperfusion inhibits VEGF expression and induces ADAMTS-1, a novel VEGF inhibitor

Basile, D. P., Fredrich, K., Chelladurai, B., Leonard, E. C. & Parrish, A. R., Apr 1 2008, In : American Journal of Physiology - Renal Physiology. 294, 4, p. F928-F936

Research output: Contribution to journalArticle

Thrombospondin 1
Disintegrins
Metalloproteases
Vascular Endothelial Growth Factor A
Reperfusion
475 Citations (Scopus)

Renal ischemic injury results in permanent damage to peritubular capillaries and influences long-term function

Basile, D. P., Donohoe, D., Roethe, K. & Osborn, J. L., Dec 19 2001, In : American Journal of Physiology - Renal Physiology. 281, 5 50-5, p. F887-F899

Research output: Contribution to journalArticle

Acute Kidney Injury
Kidney
Wounds and Injuries
Fibrosis
Ischemia
39 Citations (Scopus)

Resistance to ischemic acute renal failure in the Brown Norway rat: A new model to study cytoprotection

Basile, D. P., Donohoe, D., Cao, X. & Van Why, S. K., Jun 2004, In : Kidney international. 65, 6, p. 2201-2211 11 p.

Research output: Contribution to journalArticle

Cytoprotection
Acute Kidney Injury
Sprague Dawley Rats
Kidney
Ischemia