David Crabb

  • 9859 Citations
  • 50 h-Index
1976 …2020

Research output per year

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Publications

17β-Estradiol inhibits expression of human interleukin-6 promoter- reporter constructs by a receptor-dependent mechanism

Pottratz, S. T., Bellido, T., Mocharia, H., Crabb, D. & Manolagas, S. C., 1994, In : Journal of Clinical Investigation. 93, 3, p. 944-950 7 p.

Research output: Contribution to journalArticle

Open Access
239 Scopus citations

32-year-old man with nausea, vomiting and metastatic adenocarcinoma.

Crabb, D., Visscher, D. & Waller, B., Nov 1 1986, In : Indiana medicine : the journal of the Indiana State Medical Association. 79, 11, p. 981-988 8 p.

Research output: Contribution to journalArticle

Acetaldehyde generating enzyme systems: Roles of alcohol dehydrogenase, CYP2E1 and catalase, and speculations on the role of other enzymes and processes

Crabb, D. W. & Liangpunsakul, S., Dec 1 2007, Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide. p. 4-16 13 p. (Novartis Foundation Symposium; vol. 285).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

31 Scopus citations

Acetaldehyde Inhibits PPARγ via H2O2-Mediated c-Abl Activation in Human Hepatic Stellate Cells

Ceni, E., Crabb, D. W., Foschi, M., Mello, T., Tarocchi, M., Patussi, V., Moraldi, L., Moretti, R., Milani, S., Surrenti, C. & Galli, A., Oct 2006, In : Gastroenterology. 131, 4, p. 1235-1252 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

Activated AMPK inhibits PPAR-α and PPAR-γ transcriptional activity in hepatoma cells

Sozio, M. S., Lu, C., Zeng, Y., Liangpunsakul, S. & Crabb, D. W., Oct 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 301, 4, p. G739-G747

Research output: Contribution to journalArticle

66 Scopus citations

Activation of carbohydrate response element-binding protein by ethanol

Liangpunsakul, S., Ross, R. A. & Crabb, D. W., Feb 2013, In : Journal of Investigative Medicine. 61, 2, p. 270-277 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

ADH1, 2 and 3: genes whose times have come

Crabb, D. W., Dec 1992, In : Hepatology. 16, 6, p. 1501-1503 3 p.

Research output: Contribution to journalArticle

A direct repeat (DR-1) element in the first exon modulates transcription of the preproenkephalin A gene

Chan, R. M., Stewart, M. J. & Crabb, D. W., Apr 1 1997, In : Molecular Brain Research. 45, 1, p. 50-58 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Alcohol abstinence ameliorates the dysregulated immune profiles in patients with alcoholic hepatitis: A prospective observational study

Li, W., Amet, T., Xing, Y., Yang, D., Liangpunsakul, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Katz, B. P., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Aug 2017, In : Hepatology. 66, 2, p. 575-590 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Alcohol abstinence does not fully reverse abnormalities of mucosal-associated invariant T cells in the blood of patients with alcoholic hepatitis

Li, W., Lin, E. L., Liangpunsakul, S., Lan, J., Chalasani, S., Rane, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00052.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in chinese men

Thomasson, H. R., Edenberg, H. J., Crabb, D. W., Mai, X. L., Jerome, R. E., Li, T. K., Wang, S. P., Lin, Y. T., Lu, R. B. & Yin, S. J., Apr 1991, In : American Journal of Human Genetics. 48, 4, p. 677-681 5 p.

Research output: Contribution to journalArticle

534 Scopus citations

Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism

Thomasson, H. R., Crabb, D. W., Edenberg, H. J. & Li, T. K., Mar 1 1993, In : Behavior Genetics. 23, 2, p. 131-136 6 p.

Research output: Contribution to journalArticle

135 Scopus citations

Alcohol and lipid metabolism

Sozio, M. & Crabb, D. W., Jul 2008, In : American Journal of Physiology - Endocrinology and Metabolism. 295, 1, p. E10-E16

Research output: Contribution to journalReview article

143 Scopus citations

Alcohol and lipid metabolism

Crabb, D. W. & Liangpunsakul, S., Oct 2006, In : Journal of Gastroenterology and Hepatology (Australia). 21, SUPPL. 3, p. S56-S60

Research output: Contribution to journalArticle

81 Scopus citations

Alcohol and medication interactions

Weathermon, R. & Crabb, D. W., Dec 1 1999, In : Alcohol Research and Health. 23, 1, p. 40-54 15 p.

Research output: Contribution to journalArticle

206 Scopus citations

Alcohol and retinoids

Crabb, D. W., Pinairs, J., Hasanadka, R., Fang, M., Leo, M. A., Lieber, C. S., Tsukamoto, H., Motomura, K., Miyahara, T., Ohata, M., Bosron, W., Sanghani, S., Kedishvili, N., Shiraishi, H., Yokoyama, H., Miyagi, M., Ishii, H., Bergheim, I., Menzl, I., Parlesak, A. & 1 others, Bode, C., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 5 SUPPL., p. 207S-217S

Research output: Contribution to journalArticle

26 Scopus citations

Alcohol consumption and ethyl carbamate

Allen, N., Anderson, L. M., Beland, F. A., Bénichou, J., Beral, V., Bloomfield, K., Brooks, P. J., Cai, L., Cho, S. I., Crabb, D. W., Eriksson, P., Gapstur, S. M., Gmel, G., Griciute, L. L., Kono, S., Lachenmeier, D. W., La Vecchia, C., Marques, M. M., Miller, A. B., Rehm, J. & 41 others, Rehn-Mendoza, N., Rusyn, I., Seitz, H. K., Weiderpass, E., Willett, W. C., Yokoyama, A., Zhang, Z. F., Huici-Montagud, A., Altieri, A., Baan, R., Balbo, S., Berthiller, J., Bouvard, V., Brennan, P., Cogliano, V. J., El Ghissassi, F., Ferrari, P., Franceschi, S., Gaudin, N., Grosse, Y., Hashibe, M., Islami, F., Lee, Y. C. A., Marron, M., Mitchell, J., Napalkov, N., Secretan, B., Straif, K., Tong, W. M., Egraz, S., Javin, M., Kajo, B., Lézère, M., Lorenzen-Augros, H., Benbrahim-Tallaa, L., Freeman, C., Guha, N., Galichet, L., Hameau, A. S., Moutinho, S. & Russell, D., 2010, In : IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. 96, p. 1-1379 1379 p.

Research output: Contribution to journalReview article

106 Scopus citations

Alcohol dehydrogenase polymorphisms and predisposition to alcoholic cirrhosis

Day, C. P., James, O. F. W., Bassendine, M. F., Crabb, D. W., Li, TK. K., Poupon, R. E., Ward, P. & Balkau, B., Jul 1993, In : Hepatology. 18, 1, p. 230-232 3 p.

Research output: Contribution to journalLetter

25 Scopus citations
11 Scopus citations

Alcohol Exposure Rate Control Through Physiologically Based Pharmacokinetic Modeling

Plawecki, M. H., Zimmermann, U. S., Vitvitskiy, V., Doerschuk, P. C., Crabb, D. & O'Connor, S., Jun 2012, In : Alcoholism: Clinical and Experimental Research. 36, 6, p. 1042-1049 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Alcoholic liver disease

Lumeng, L. & Crabb, D. W., May 5 2001, In : Current Opinion in Gastroenterology. 17, 3, p. 211-220 10 p.

Research output: Contribution to journalReview article

25 Scopus citations

Alcoholic liver disease

Lumeng, L. & Crabb, D. W., Dec 1 2000, In : Current Opinion in Gastroenterology. 16, 3, p. 208-218 11 p.

Research output: Contribution to journalReview article

29 Scopus citations

Alcoholic Liver Diseases

Liangpunsakul, S. & Crabb, D. W., Feb 17 2009, Textbook of Gastroenterology, Fifth Edition. Blackwell Publishing Ltd, Vol. 2. p. 2247-2273 27 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Alcoholic myopathy and acetaldehyde

Preedy, V. R., Crabb, D. W., Farrés, J. & Emery, P. W., Dec 1 2007, Acetaldehyde-Related Pathology: Bridging the Trans-Disciplinary Divide. p. 158-177 20 p. (Novartis Foundation Symposium; vol. 285).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

15 Scopus citations

Alcoholism research: recent developments.

McHenry, R. & Crabb, D. W., Aug 1985, In : Indiana medicine : the journal of the Indiana State Medical Association. 78, 8, p. 663-668 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Alcohol sensitivity, alcohol metabolism, risk of alcoholism, and the role of alcohol and aldehyde dehydrogenase genotypes

Crabb, D. W., Dipple, K. M. & Thomasson, H. R., Sep 1993, In : The Journal of Laboratory and Clinical Medicine. 122, 3, p. 234-240 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Alcohol's influences on various disease states

Weathermon, R. & Crabb, D. W., Dec 1 1999, In : Alcohol Research and Health. 23, 1, p. 52-53 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

A method for increasing the sensitivity of chloramphenicol acetyltransferase assays in extracts of transfected cultured cells

Crabb, D. W. & Dixon, J. E., May 15 1987, In : Analytical biochemistry. 163, 1, p. 88-92 5 p.

Research output: Contribution to journalArticle

130 Scopus citations

An A/G polymorphism in the promoter of mitochondrial aldehyde dehydrogenase (ALDH2): Effects of the sequence variant on transcription factor binding and promoter strength

Chou, W. Y., Stewart, M. J., Carr, L. G., Zheng, D., Stewart, T. R., Williams, A., Pinaire, J. & Crabb, D. W., Jun 1 1999, In : Alcoholism: Clinical and Experimental Research. 23, 6, p. 963-968 6 p.

Research output: Contribution to journalReview article

49 Scopus citations

A new family of protein kinases- The mitochondrial protein kinases

Harris, R. A., Popov, K. M., Zhao, Y., Kedishvili, N. Y., Shimomura, Y. & Crabb, D. W., 1995, In : Advances in Enzyme Regulation. 35, C, p. 147-158,IN17,159-162

Research output: Contribution to journalArticle

63 Scopus citations

A new instrument for measuring patient utilities for colorectal cancer outcome states

Ness, R., Crabb, D., Holmes, A., Klein, R., Rex, D. & Dittus, R., Jan 1 1997, In : Gastrointestinal endoscopy. 45, 4, p. AB113

Research output: Contribution to journalArticle

An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis

for the TREAT Consortium, Nov 2 2017, In : Scandinavian Journal of Gastroenterology. 52, 11, p. 1263-1269 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

An Initial Assessment of the Utility of Validated Alcohol and Drug Screening Tools in Predicting 30-Day Readmission to Adult General Medicine Wards

Gerke, S. P., Agley, J. D., Wilson, C., Gassman, R. A., Forys, P. & Crabb, D. W., Jul 1 2018, In : American Journal of Medical Quality. 33, 4, p. 397-404 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Antidiabetic thiazolidinediones induce ductal differentiation but not apoptosis in pancreatic cancer cells

Ceni, E., Mello, T., Tarocchi, M., Crabb, D. W., Caldini, A., Invernizzi, P., Surrenti, C., Milani, S. & Galli, A., Feb 28 2005, In : World Journal of Gastroenterology. 11, 8, p. 1122-1130 9 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro

Galli, A., Crabb, D. W., Ceni, E., Salzano, R., Mello, T., Svegliati-Baroni, G., Ridolfi, F., Trozzi, L., Surrenti, C. & Casini, A., Jan 1 2002, In : Gastroenterology. 122, 7, p. 1924-1940 17 p.

Research output: Contribution to journalArticle

361 Scopus citations

Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARγ independent mechanisms

Galli, A., Ceni, E., Crabb, D. W., Mello, T., Salzano, R., Grappone, C., Milani, S., Surrenti, E., Surrenti, C. & Casini, A., Nov 1 2004, In : Gut. 53, 11, p. 1688-1697 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

A polymorphism in the rat liver mitochondrial ALDH2 gene is associated with alcohol drinking behavior

Carr, L., Mellencamp, B., Crabb, D., Lumeng, L. & Li, T. K., Jun 11 1991, In : Advances in Experimental Medicine and Biology. 284, p. 61-65 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

A proteomic workflow for discovery of serum carrier protein-bound biomarker candidates of alcohol abuse using LC-MS/MS

Lai, X., Liangpunsakul, S., Crabb, D. W., Ringham, H. N. & Witzmann, F. A., Jun 1 2009, In : ELECTROPHORESIS. 30, 12, p. 2207-2214 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Assaying the reporter gene chloramphenicol acetyltransferase

Crabb, D. W., Minth, C. D. & Dixon, J. E., Jan 1 1989, In : Methods in Enzymology. 168, C, p. 690-701 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Assessing the relationship between medical residents' perceived barriers to SBIRT implementation and their documentation of SBIRT in clinical practice

Agley, J., Gassman, R. A., Vannerson, J. & Crabb, D., Aug 2014, In : Public Health. 128, 8, p. 755-758 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Assignment of the gene for the E1α subunit of branched chain α-ketoacid dehydrogenase to chromosome 19

Crabb, D. W., Deaven, L. L., Luedemann, M., Zhang, B. & Harris, R. A., Jan 1 1989, In : Cytogenetics and Cell Genetics. 50, 1, p. 40-41 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Association Between Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism and Alcoholic Liver Disease

Chang, B., Hao, S., Zhang, L., Gao, M., Sun, Y., Huang, A., Teng, G., Li, B., Crabb, D. W., Kusumanchi, P., Wang, L., Liangpunsakul, S. & Zou, Z., Jul 2018, In : American Journal of the Medical Sciences. 356, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Association of the aldehyde dehydrogenase 2 promoter polymorphism with alcohol consumption and reactions in an American Jewish population

Fischer, M., Wetherill, L. F., Carr, L. G., You, M. & Crabb, D. W., Oct 1 2007, In : Alcoholism: Clinical and Experimental Research. 31, 10, p. 1654-1659 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Binding and activation of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4

Stewart, M. J., Dipple, K. M., Estonius, M., Nakshatri, H., Everett, L. M. & Crabb, D. W., Aug 20 1998, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1399, 2-3, p. 181-186 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Biological markers for increased risk of alcoholism and for quantitation of alcohol consumption

Crabb, D. W., Feb 1990, In : Journal of Clinical Investigation. 85, 2, p. 311-315 5 p.

Research output: Contribution to journalReview article

Open Access
42 Scopus citations

Catabolism of isobutyrate by colonocytes

Jaskiewicz, J., Zhao, Y., Hawes, J. W., Shimomura, Y., Crabb, D. W. & Harris, R. A., Mar 15 1996, In : Archives of Biochemistry and Biophysics. 327, 2, p. 265-270 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

CCAAT/enhancer binding protein binds and activates the promoter of the rat class I alcohol dehydrogenase gene

Potter, J. J., Mezey, E., Christy, R. J., Crabb, D. W., Stein, P. M. & Yang, V. W., Mar 1991, In : Archives of Biochemistry and Biophysics. 285, 2, p. 246-251 6 p.

Research output: Contribution to journalArticle

28 Scopus citations