David Crabb

  • 9859 Citations
  • 50 h-Index
1976 …2020

Research output per year

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Publications

Article

17β-Estradiol inhibits expression of human interleukin-6 promoter- reporter constructs by a receptor-dependent mechanism

Pottratz, S. T., Bellido, T., Mocharia, H., Crabb, D. & Manolagas, S. C., 1994, In : Journal of Clinical Investigation. 93, 3, p. 944-950 7 p.

Research output: Contribution to journalArticle

Open Access
239 Scopus citations

32-year-old man with nausea, vomiting and metastatic adenocarcinoma.

Crabb, D., Visscher, D. & Waller, B., Nov 1 1986, In : Indiana medicine : the journal of the Indiana State Medical Association. 79, 11, p. 981-988 8 p.

Research output: Contribution to journalArticle

Acetaldehyde Inhibits PPARγ via H2O2-Mediated c-Abl Activation in Human Hepatic Stellate Cells

Ceni, E., Crabb, D. W., Foschi, M., Mello, T., Tarocchi, M., Patussi, V., Moraldi, L., Moretti, R., Milani, S., Surrenti, C. & Galli, A., Oct 2006, In : Gastroenterology. 131, 4, p. 1235-1252 18 p.

Research output: Contribution to journalArticle

36 Scopus citations

Activated AMPK inhibits PPAR-α and PPAR-γ transcriptional activity in hepatoma cells

Sozio, M. S., Lu, C., Zeng, Y., Liangpunsakul, S. & Crabb, D. W., Oct 2011, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 301, 4, p. G739-G747

Research output: Contribution to journalArticle

66 Scopus citations

Activation of carbohydrate response element-binding protein by ethanol

Liangpunsakul, S., Ross, R. A. & Crabb, D. W., Feb 2013, In : Journal of Investigative Medicine. 61, 2, p. 270-277 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

ADH1, 2 and 3: genes whose times have come

Crabb, D. W., Dec 1992, In : Hepatology. 16, 6, p. 1501-1503 3 p.

Research output: Contribution to journalArticle

A direct repeat (DR-1) element in the first exon modulates transcription of the preproenkephalin A gene

Chan, R. M., Stewart, M. J. & Crabb, D. W., Apr 1 1997, In : Molecular Brain Research. 45, 1, p. 50-58 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Alcohol abstinence ameliorates the dysregulated immune profiles in patients with alcoholic hepatitis: A prospective observational study

Li, W., Amet, T., Xing, Y., Yang, D., Liangpunsakul, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Katz, B. P., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Aug 2017, In : Hepatology. 66, 2, p. 575-590 16 p.

Research output: Contribution to journalArticle

11 Scopus citations

Alcohol abstinence does not fully reverse abnormalities of mucosal-associated invariant T cells in the blood of patients with alcoholic hepatitis

Li, W., Lin, E. L., Liangpunsakul, S., Lan, J., Chalasani, S., Rane, S., Puri, P., Kamath, P. S., Sanyal, A. J., Shah, V. H., Radaeva, S., Crabb, D. W., Chalasani, N. & Yu, Q., Jun 1 2019, In : Clinical and translational gastroenterology. 10, 6, e-00052.

Research output: Contribution to journalArticle

Open Access
4 Scopus citations

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in chinese men

Thomasson, H. R., Edenberg, H. J., Crabb, D. W., Mai, X. L., Jerome, R. E., Li, T. K., Wang, S. P., Lin, Y. T., Lu, R. B. & Yin, S. J., Apr 1991, In : American Journal of Human Genetics. 48, 4, p. 677-681 5 p.

Research output: Contribution to journalArticle

534 Scopus citations

Alcohol and aldehyde dehydrogenase polymorphisms and alcoholism

Thomasson, H. R., Crabb, D. W., Edenberg, H. J. & Li, T. K., Mar 1 1993, In : Behavior Genetics. 23, 2, p. 131-136 6 p.

Research output: Contribution to journalArticle

135 Scopus citations

Alcohol and lipid metabolism

Crabb, D. W. & Liangpunsakul, S., Oct 2006, In : Journal of Gastroenterology and Hepatology (Australia). 21, SUPPL. 3, p. S56-S60

Research output: Contribution to journalArticle

81 Scopus citations

Alcohol and medication interactions

Weathermon, R. & Crabb, D. W., Dec 1 1999, In : Alcohol Research and Health. 23, 1, p. 40-54 15 p.

Research output: Contribution to journalArticle

206 Scopus citations

Alcohol and retinoids

Crabb, D. W., Pinairs, J., Hasanadka, R., Fang, M., Leo, M. A., Lieber, C. S., Tsukamoto, H., Motomura, K., Miyahara, T., Ohata, M., Bosron, W., Sanghani, S., Kedishvili, N., Shiraishi, H., Yokoyama, H., Miyagi, M., Ishii, H., Bergheim, I., Menzl, I., Parlesak, A. & 1 others, Bode, C., 2001, In : Alcoholism: Clinical and Experimental Research. 25, 5 SUPPL., p. 207S-217S

Research output: Contribution to journalArticle

26 Scopus citations
11 Scopus citations

Alcohol Exposure Rate Control Through Physiologically Based Pharmacokinetic Modeling

Plawecki, M. H., Zimmermann, U. S., Vitvitskiy, V., Doerschuk, P. C., Crabb, D. & O'Connor, S., Jun 2012, In : Alcoholism: Clinical and Experimental Research. 36, 6, p. 1042-1049 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Alcoholism research: recent developments.

McHenry, R. & Crabb, D. W., Aug 1985, In : Indiana medicine : the journal of the Indiana State Medical Association. 78, 8, p. 663-668 6 p.

Research output: Contribution to journalArticle

30 Scopus citations

Alcohol sensitivity, alcohol metabolism, risk of alcoholism, and the role of alcohol and aldehyde dehydrogenase genotypes

Crabb, D. W., Dipple, K. M. & Thomasson, H. R., Sep 1993, In : The Journal of Laboratory and Clinical Medicine. 122, 3, p. 234-240 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Alcohol's influences on various disease states

Weathermon, R. & Crabb, D. W., Dec 1 1999, In : Alcohol Research and Health. 23, 1, p. 52-53 2 p.

Research output: Contribution to journalArticle

13 Scopus citations

A method for increasing the sensitivity of chloramphenicol acetyltransferase assays in extracts of transfected cultured cells

Crabb, D. W. & Dixon, J. E., May 15 1987, In : Analytical biochemistry. 163, 1, p. 88-92 5 p.

Research output: Contribution to journalArticle

130 Scopus citations

A new family of protein kinases- The mitochondrial protein kinases

Harris, R. A., Popov, K. M., Zhao, Y., Kedishvili, N. Y., Shimomura, Y. & Crabb, D. W., 1995, In : Advances in Enzyme Regulation. 35, C, p. 147-158,IN17,159-162

Research output: Contribution to journalArticle

63 Scopus citations

A new instrument for measuring patient utilities for colorectal cancer outcome states

Ness, R., Crabb, D., Holmes, A., Klein, R., Rex, D. & Dittus, R., Jan 1 1997, In : Gastrointestinal endoscopy. 45, 4, p. AB113

Research output: Contribution to journalArticle

An exploratory genome-wide analysis of genetic risk for alcoholic hepatitis

for the TREAT Consortium, Nov 2 2017, In : Scandinavian Journal of Gastroenterology. 52, 11, p. 1263-1269 7 p.

Research output: Contribution to journalArticle

7 Scopus citations

An Initial Assessment of the Utility of Validated Alcohol and Drug Screening Tools in Predicting 30-Day Readmission to Adult General Medicine Wards

Gerke, S. P., Agley, J. D., Wilson, C., Gassman, R. A., Forys, P. & Crabb, D. W., Jul 1 2018, In : American Journal of Medical Quality. 33, 4, p. 397-404 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Antidiabetic thiazolidinediones induce ductal differentiation but not apoptosis in pancreatic cancer cells

Ceni, E., Mello, T., Tarocchi, M., Crabb, D. W., Caldini, A., Invernizzi, P., Surrenti, C., Milani, S. & Galli, A., Feb 28 2005, In : World Journal of Gastroenterology. 11, 8, p. 1122-1130 9 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Antidiabetic thiazolidinediones inhibit collagen synthesis and hepatic stellate cell activation in vivo and in vitro

Galli, A., Crabb, D. W., Ceni, E., Salzano, R., Mello, T., Svegliati-Baroni, G., Ridolfi, F., Trozzi, L., Surrenti, C. & Casini, A., Jan 1 2002, In : Gastroenterology. 122, 7, p. 1924-1940 17 p.

Research output: Contribution to journalArticle

361 Scopus citations

Antidiabetic thiazolidinediones inhibit invasiveness of pancreatic cancer cells via PPARγ independent mechanisms

Galli, A., Ceni, E., Crabb, D. W., Mello, T., Salzano, R., Grappone, C., Milani, S., Surrenti, E., Surrenti, C. & Casini, A., Nov 1 2004, In : Gut. 53, 11, p. 1688-1697 10 p.

Research output: Contribution to journalArticle

81 Scopus citations

A polymorphism in the rat liver mitochondrial ALDH2 gene is associated with alcohol drinking behavior

Carr, L., Mellencamp, B., Crabb, D., Lumeng, L. & Li, T. K., Jun 11 1991, In : Advances in Experimental Medicine and Biology. 284, p. 61-65 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

A proteomic workflow for discovery of serum carrier protein-bound biomarker candidates of alcohol abuse using LC-MS/MS

Lai, X., Liangpunsakul, S., Crabb, D. W., Ringham, H. N. & Witzmann, F. A., Jun 1 2009, In : ELECTROPHORESIS. 30, 12, p. 2207-2214 8 p.

Research output: Contribution to journalArticle

18 Scopus citations

Assaying the reporter gene chloramphenicol acetyltransferase

Crabb, D. W., Minth, C. D. & Dixon, J. E., Jan 1 1989, In : Methods in Enzymology. 168, C, p. 690-701 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Assessing the relationship between medical residents' perceived barriers to SBIRT implementation and their documentation of SBIRT in clinical practice

Agley, J., Gassman, R. A., Vannerson, J. & Crabb, D., Aug 2014, In : Public Health. 128, 8, p. 755-758 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Assignment of the gene for the E1α subunit of branched chain α-ketoacid dehydrogenase to chromosome 19

Crabb, D. W., Deaven, L. L., Luedemann, M., Zhang, B. & Harris, R. A., Jan 1 1989, In : Cytogenetics and Cell Genetics. 50, 1, p. 40-41 2 p.

Research output: Contribution to journalArticle

7 Scopus citations

Association Between Aldehyde Dehydrogenase 2 Glu504Lys Polymorphism and Alcoholic Liver Disease

Chang, B., Hao, S., Zhang, L., Gao, M., Sun, Y., Huang, A., Teng, G., Li, B., Crabb, D. W., Kusumanchi, P., Wang, L., Liangpunsakul, S. & Zou, Z., Jul 2018, In : American Journal of the Medical Sciences. 356, 1, p. 10-14 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Association of the aldehyde dehydrogenase 2 promoter polymorphism with alcohol consumption and reactions in an American Jewish population

Fischer, M., Wetherill, L. F., Carr, L. G., You, M. & Crabb, D. W., Oct 1 2007, In : Alcoholism: Clinical and Experimental Research. 31, 10, p. 1654-1659 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Binding and activation of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4

Stewart, M. J., Dipple, K. M., Estonius, M., Nakshatri, H., Everett, L. M. & Crabb, D. W., Aug 20 1998, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1399, 2-3, p. 181-186 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Catabolism of isobutyrate by colonocytes

Jaskiewicz, J., Zhao, Y., Hawes, J. W., Shimomura, Y., Crabb, D. W. & Harris, R. A., Mar 15 1996, In : Archives of Biochemistry and Biophysics. 327, 2, p. 265-270 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

CCAAT/enhancer binding protein binds and activates the promoter of the rat class I alcohol dehydrogenase gene

Potter, J. J., Mezey, E., Christy, R. J., Crabb, D. W., Stein, P. M. & Yang, V. W., Mar 1991, In : Archives of Biochemistry and Biophysics. 285, 2, p. 246-251 6 p.

Research output: Contribution to journalArticle

28 Scopus citations
5 Scopus citations

Central nervous system control of alcohol dehydrogenase activity in rats

Crabb, D. W., Morzorati, S. L., Simon, J. R. & Li, T. K., Dec 23 1985, In : Life Sciences. 37, 25, p. 2381-2387 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Characterization of the 5'-flanking sequence of rat class I alcohol dehydrogenase gene

Cortese, J. F., Majewski, J. L., Crabb, D. W., Edenberg, H. J. & Yang, V. W., Jan 1 1994, In : Journal of Biological Chemistry. 269, 34, p. 21898-21906 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Chemical Modification and Site-Directed Mutagenesis Studies of Rat 3-Hydroxyisobutyrate Dehydrogenase

Hawes, J. W., Crabb, D. W., Chan, R. M., Harris, R. A. & Rougraff, P. M., Sep 1 1995, In : Biochemistry. 34, 13, p. 4231-4237 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Chronic Free-Choice Drinking in Crossed High Alcohol Preferring Mice Leads to Sustained Blood Ethanol Levels and Metabolic Tolerance Without Evidence of Liver Damage

Matson, L., Liangpunsakul, S., Crabb, D., Buckingham, A., Ross, R. A., Halcomb, M. & Grahame, N., Feb 1 2013, In : Alcoholism: Clinical and Experimental Research. 37, 2, p. 194-201 8 p.

Research output: Contribution to journalArticle

13 Scopus citations
21 Scopus citations
1 Scopus citations

CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution

Kedishvili, N. Y., Popov, K. M., Rougraff, P. M., Zhao, Y., Crabb, D. W. & Harris, R. A., Jan 1 1992, In : Journal of Biological Chemistry. 267, 27, p. 19724-19729 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Comparison of Three Nonsurgical Comparison Treatments for Bleeding Esophageal Varices

O'Connor, K. W., Lehman, G., Yune, H., Brunelle, R., Christiansen, P., Hast, J., Compton, M., McHenry, R., Klatte, E., Cockerill, E., Holden, R., Becker, G., Kopecky, K., Hawes, R., Pound, D., Rex, D., Lui, A., Snodgrass, P., Weddle, R., Crabb, D. & 1 others, Lumeng, L., Jan 1 1989, In : Gastroenterology. 96, 2, p. 899-906 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Comparison of three nonsurgical treatments for bleeding esophageal varices

O'Connor, K. W., Lehman, G., Yune, H., Brunelle, R., Christiansen, P., Hast, J., Compton, M., McHenry, R., Klatte, E., Cockerill, E., Holden, R., Becker, G., Kopecky, K., Hawes, R., Pound, D., Rex, D., Lui, A., Snodgrass, P., Weddle, R., Crabb, D. & 1 others, Lumeng, L., Mar 1989, In : Gastroenterology. 96, 3, p. 899-906 8 p.

Research output: Contribution to journalArticle

2 Scopus citations