David Crabb

  • 9859 Citations
  • 50 h-Index
1976 …2020

Research output per year

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Publications

1993
15 Scopus citations
1992

ADH1, 2 and 3: genes whose times have come

Crabb, D. W., Dec 1992, In : Hepatology. 16, 6, p. 1501-1503 3 p.

Research output: Contribution to journalArticle

CoA-dependent methylmalonate-semialdehyde dehydrogenase, a unique member of the aldehyde dehydrogenase superfamily. cDNA cloning, evolutionary relationships, and tissue distribution

Kedishvili, N. Y., Popov, K. M., Rougraff, P. M., Zhao, Y., Crabb, D. W. & Harris, R. A., Jan 1 1992, In : Journal of Biological Chemistry. 267, 27, p. 19724-19729 6 p.

Research output: Contribution to journalArticle

54 Scopus citations

Corticosterone Induces Rat Liver Alcohol Dehydrogenase mRNA But Not Enzyme Protein or Activity

Qulali, M. & Crabb, D. W., Jun 1992, In : Alcoholism: Clinical and Experimental Research. 16, 3, p. 427-431 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Erratum: 'Investigations of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol-related end- organ damage' (Hepatology (1991) 14 (798-801))

Day, C. P., Bashir, R., James, O. F. W., Bassendine, M. F., Crabb, D. W., Thomasson, H. R., Li, T. K. & Edenberg, H. J., Jan 1 1992, In : Hepatology. 15, 4, 1 p.

Research output: Contribution to journalComment/debate

19 Scopus citations

Highlights of the RSA Alcohol Symposium on Enzymes of Metabolism

Crabb, D. W. & Lands, W., Oct 1992, In : Alcoholism: Clinical and Experimental Research. 16, 5, p. 870-874 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

Molecular cloning of the E1β subunit of the rat branched chain α-ketoacid dehydrogenase

Zhao, Y., Kuntz, M. J., Harris, R. A. & Crabb, D. W., Sep 24 1992, In : BBA - Gene Structure and Expression. 1132, 2, p. 207-210 4 p.

Research output: Contribution to journalArticle

9 Scopus citations

The first 22 base pairs of the proximal promoter of the rat class I alcohol dehydrogenase gene is bipartite and interacts with multiple DNA-binding proteins

Potter, J. J., Mezey, E., Cornelius, P., Crabb, D. W. & Yang, V. W., Jun 1992, In : Archives of Biochemistry and Biophysics. 295, 2, p. 360-368 9 p.

Research output: Contribution to journalArticle

21 Scopus citations
1991

Alcohol and aldehyde dehydrogenase genotypes and alcoholism in chinese men

Thomasson, H. R., Edenberg, H. J., Crabb, D. W., Mai, X. L., Jerome, R. E., Li, T. K., Wang, S. P., Lin, Y. T., Lu, R. B. & Yin, S. J., Apr 1991, In : American Journal of Human Genetics. 48, 4, p. 677-681 5 p.

Research output: Contribution to journalArticle

534 Scopus citations

A polymorphism in the rat liver mitochondrial ALDH2 gene is associated with alcohol drinking behavior

Carr, L., Mellencamp, B., Crabb, D., Lumeng, L. & Li, T. K., Jun 11 1991, In : Advances in Experimental Medicine and Biology. 284, p. 61-65 5 p.

Research output: Contribution to journalArticle

6 Scopus citations

CCAAT/enhancer binding protein binds and activates the promoter of the rat class I alcohol dehydrogenase gene

Potter, J. J., Mezey, E., Christy, R. J., Crabb, D. W., Stein, P. M. & Yang, V. W., Mar 1991, In : Archives of Biochemistry and Biophysics. 285, 2, p. 246-251 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Endocrine regulation and methylation patterns of rat class I alcohol dehydrogenase in liver and kidney

Crabb, D. W., Qulali, M. & Dipple, K. M., Jun 11 1991, In : Advances in Experimental Medicine and Biology. 284, p. 277-284 8 p.

Research output: Contribution to journalArticle

8 Scopus citations

Estradiol induces class I alcohol dehydrogenase activity and mRNA in kidney of female rats

Qulali, M., Ross, R. A. & Crabb, D. W., Aug 1 1991, In : Archives of Biochemistry and Biophysics. 288, 2, p. 406-413 8 p.

Research output: Contribution to journalArticle

36 Scopus citations

Investigation of the role of polymorphisms at the alcohol and aldehyde dehydrogenase loci in genetic predisposition to alcohol‐related end‐organ damage

Day, C. P., Bashir, R., James, O. F. W., Bassendine, M. F., Crabb, D. W., Thomasson, H. R., Li, TK. K. & Edenberg, H. J., Nov 1991, In : Hepatology. 14, 5, p. 798-801 4 p.

Research output: Contribution to journalArticle

143 Scopus citations

Methylmalonic aciduria presenting in an adult

Gerhardt, M., Burke, E. M., Brandt, I. K. & Crabb, D. W., Jan 1 1991, In : Journal of Inherited Metabolic Disease. 14, 1, p. 113-114 2 p.

Research output: Contribution to journalArticle

7 Scopus citations
18 Scopus citations

Polymorphism of the Rat Liver Mitochondrial Aldehyde Dehydrogenase cDNA

Carr, L. G., Mellencamp, R. J., Crabb, D. W., Weiner, H., Lumeng, L. & Li, T. K., Oct 1991, In : Alcoholism: Clinical and Experimental Research. 15, 5, p. 753-756 4 p.

Research output: Contribution to journalArticle

14 Scopus citations
1990

Biological markers for increased risk of alcoholism and for quantitation of alcohol consumption

Crabb, D. W., Feb 1990, In : Journal of Clinical Investigation. 85, 2, p. 311-315 5 p.

Research output: Contribution to journalReview article

Open Access
42 Scopus citations
31 Scopus citations

Regulation of the branched-chain α-ketoacid dehydrogenase and elucidation of a molecular basis for maple syrup urine disease

Harris, R. A., Zhang, B., Goodwin, G. W., Kuntz, M. J., Shimomura, Y., Rougraff, P., Dexter, P., Zhao, Y., Gibson, R. & Crabb, D. W., 1990, In : Advances in Enzyme Regulation. 30, C, p. 245-256 12 p.

Research output: Contribution to journalArticle

59 Scopus citations

Sequence of the E1β subunit of branched-chain α-ketoacid dehydrogenase in two patients with thiamine-responsive maple syrup urine disease

Zhang, B., Wappner, R. S., Brandt, I. K., Harris, R. A. & Crabb, D. W., Apr 18 1990, In : American Journal of Human Genetics. 46, 4, p. 843-846 4 p.

Research output: Contribution to journalArticle

9 Scopus citations
1989

Assaying the reporter gene chloramphenicol acetyltransferase

Crabb, D. W., Minth, C. D. & Dixon, J. E., Jan 1 1989, In : Methods in Enzymology. 168, C, p. 690-701 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Assignment of the gene for the E1α subunit of branched chain α-ketoacid dehydrogenase to chromosome 19

Crabb, D. W., Deaven, L. L., Luedemann, M., Zhang, B. & Harris, R. A., Jan 1 1989, In : Cytogenetics and Cell Genetics. 50, 1, p. 40-41 2 p.

Research output: Contribution to journalArticle

7 Scopus citations
5 Scopus citations
21 Scopus citations

Comparison of Three Nonsurgical Comparison Treatments for Bleeding Esophageal Varices

O'Connor, K. W., Lehman, G., Yune, H., Brunelle, R., Christiansen, P., Hast, J., Compton, M., McHenry, R., Klatte, E., Cockerill, E., Holden, R., Becker, G., Kopecky, K., Hawes, R., Pound, D., Rex, D., Lui, A., Snodgrass, P., Weddle, R., Crabb, D. & 1 others, Lumeng, L., Jan 1 1989, In : Gastroenterology. 96, 2, p. 899-906 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Comparison of three nonsurgical treatments for bleeding esophageal varices

O'Connor, K. W., Lehman, G., Yune, H., Brunelle, R., Christiansen, P., Hast, J., Compton, M., McHenry, R., Klatte, E., Cockerill, E., Holden, R., Becker, G., Kopecky, K., Hawes, R., Pound, D., Rex, D., Lui, A., Snodgrass, P., Weddle, R., Crabb, D. & 1 others, Lumeng, L., Mar 1989, In : Gastroenterology. 96, 3, p. 899-906 8 p.

Research output: Contribution to journalArticle

2 Scopus citations
Open Access
35 Scopus citations

Genotypes for aldehyde dehydrogenase deficiency and alcohol sensitivity. The inactive ALDH22 allele is dominant

Crabb, D. W., Edenberg, H. J., Bosron, W. F. & Li, T. K., Jan 1 1989, In : Journal of Clinical Investigation. 83, 1, p. 314-316 3 p.

Research output: Contribution to journalArticle

Open Access
440 Scopus citations

Immunocytochemistry of Alcohol Dehydrogenase in the Rat Central Nervous System

Kerr, J. T., Maxwell, D. S. & Crabb, D. W., Dec 1989, In : Alcoholism: Clinical and Experimental Research. 13, 6, p. 730-735 6 p.

Research output: Contribution to journalArticle

32 Scopus citations

Localization of the human gene for the Elα subunit of branched chain keto acid dehydrogenase (BCKDHA) to chromosome 19q13.1 → q13.2

Fekete, G., Plattner, R., Crabb, D. W., Zhang, B., Harris, R. A., Heerema, N. & Palmer, C. G., Jan 1 1989, In : Cytogenetic and Genome Research. 50, 4, p. 236-237 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Regulation of the expression of the rat alcohol dehydrogenase gene by glucocorticoids.

Qulali, M., Wolfla, C. E., Ross, R. A. & Crabb, D. W., 1989, In : Progress in clinical and biological research. 290, p. 143-153 11 p.

Research output: Contribution to journalArticle

Structure and expression of the rat class I alcohol dehydrogenase gene

Crabb, D. W., Stein, P. M., Dipple, K. M., Hittle, J. B., Sidhu, R., Qulali, M., Zhang, K. & Edenberg, H. J., Nov 1989, In : Genomics. 5, 4, p. 906-914 9 p.

Research output: Contribution to journalArticle

32 Scopus citations

The heat-shock response in cultured cells exposed to ethanol and its metabolites

Walsh, K. H. & Crabb, D. W., Jan 1 1989, In : Journal of Laboratory and Clinical Medicine. 114, 5, p. 563-567 5 p.

Research output: Contribution to journalArticle

9 Scopus citations
1988

Induction of alcohol dehydrogenase activity and mRNA in hepatoma cells by dexamethasone

Wolfla, C. E., Ross, R. A. & Crabb, D. W., May 15 1988, In : Archives of Biochemistry and Biophysics. 263, 1, p. 69-76 8 p.

Research output: Contribution to journalArticle

42 Scopus citations

Nucleotide and deduced amino acid sequence of the E1α subunit of human liver branched-chain α-ketoacid dehydrogenase

Zhang, B., Crabb, D. W. & Harris, R. A., Sep 15 1988, In : Gene. 69, 1, p. 159-164 6 p.

Research output: Contribution to journalArticle

25 Scopus citations

Oral medications for upper gastrointestinal endoscopy using a small diameter endoscope

Pound, D. C., O’Connor, K. W., Brown, E. D., Weddle, R., McHenry, R., Crabb, D., Brunelle, R. & Lehman, G. A., Jan 1 1988, In : Gastrointestinal endoscopy. 34, 4, p. 327-331 5 p.

Research output: Contribution to journalArticle

12 Scopus citations

Purification and characterization of 3-hydroxyisobutyrate dehydrogenase from rabbit liver

Rougraff, P. M., Paxton, R., Kuntz, M. J., Crabb, D. W. & Harris, R. A., Jan 1 1988, In : Journal of Biological Chemistry. 263, 1, p. 327-331 5 p.

Research output: Contribution to journalArticle

34 Scopus citations

The molecular biology of alcohol dehydrogenase: Implications for the control of alcohol metabolism

Hittle, J. B. & Crabb, D. W., Jul 1988, In : The Journal of Laboratory and Clinical Medicine. 112, 1, p. 7-15 9 p.

Research output: Contribution to journalReview article

13 Scopus citations
1987

A method for increasing the sensitivity of chloramphenicol acetyltransferase assays in extracts of transfected cultured cells

Crabb, D. W. & Dixon, J. E., May 15 1987, In : Analytical biochemistry. 163, 1, p. 88-92 5 p.

Research output: Contribution to journalArticle

130 Scopus citations
1 Scopus citations

Ethanol metabolism

Crabb, D. W., Bosron, W. F. & Li, T. K., 1987, In : Pharmacology and Therapeutics. 34, 1, p. 59-73 15 p.

Research output: Contribution to journalArticle

92 Scopus citations

Loss of growth hormone-dependent characteristics of rat hepatocytes in culture

Crabb, D. W. & Roepke, J., Apr 1 1987, In : In Vitro Cellular & Developmental Biology. 23, 4, p. 303-307 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Loss of sexual differentiation of rat hepatocytes in short-term culture.

Roepke, J. E. & Crabb, D. W., 1987, In : Alcohol and alcoholism (Oxford, Oxfordshire). Supplement.. 1, p. 263-264 2 p.

Research output: Contribution to journalArticle

1 Scopus citations

Molecular cloning of a cDNA for the E1 alpha subunit of rat liver branched chain alpha-ketoacid dehydrogenase.

Zhang, B., Kuntz, M. J., Goodwin, G. W., Harris, R. A. & Crabb, D. W., Nov 5 1987, In : The Journal of biological chemistry. 262, 31, p. 15220-15224 5 p.

Research output: Contribution to journalArticle

32 Scopus citations

Studies on the hormonal regulation of rat liver alcohol dehydrogenase.

Crabb, D. W., Jan 1 1987, In : Progress in clinical and biological research. 232, p. 245-258 14 p.

Research output: Contribution to journalArticle

5 Scopus citations
1986

32-year-old man with nausea, vomiting and metastatic adenocarcinoma.

Crabb, D., Visscher, D. & Waller, B., Nov 1 1986, In : Indiana medicine : the journal of the Indiana State Medical Association. 79, 11, p. 981-988 8 p.

Research output: Contribution to journalArticle

Complete amino acid sequence of rat liver alcohol dehydrogenase deduced from the cDNA sequence

Crabb, D. W. & Edenberg, H. J., 1986, In : Gene. 48, 2-3, p. 287-291 5 p.

Research output: Contribution to journalArticle

39 Scopus citations

Role of the pituitary and neonatal androgenic imprinting in the hormonal regulation of liver alcohol dehydrogenase activity

Crabb, D. W., Bosron, W. F. & Ting-Kai Li, L., May 1 1986, In : Biochemical Pharmacology. 35, 9, p. 1527-1532 6 p.

Research output: Contribution to journalArticle

13 Scopus citations