David Ingram

  • 9730 Citations
  • 48 h-Index
1991 …2018

Research output per year

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Publications

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Article
2018

Neurofibromin deficiency induces endothelial cell proliferation and retinal neovascularization

Zhang, H., Hudson, F. Z., Xu, Z., Tritz, R., Rojas, M., Patel, C., Haigh, S. B., Bordán, Z., Ingram, D. A., Fulton, D. J., Weintraub, N. L., Caldwell, R. B. & Stansfield, B. K., May 2018, In : Investigative Ophthalmology and Visual Science. 59, 6, p. 2520-2528 9 p.

Research output: Contribution to journalArticle

1 Scopus citations
2017

Adult venous endothelium is a niche for highly proliferative and vasculogenic endothelial colony-forming cells

Green, L., Ofstein, R. H., Rapp, B., Saadatzadeh, M. R., Bhavsar, J. R., Fajardo, A., Dalsing, M. C., Ingram, D. A. & Murphy, M. P., Dec 2017, In : Journal of vascular surgery. 66, 6, p. 1854-1863 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Antenatal determinants of bronchopulmonary dysplasia and late respiratory disease in preterm infants

Morrow, L. A., Wagner, B. D., Ingram, D., Poindexter, B. B., Schibler, K., Cotten, C. M., Dagle, J., Sontag, M. K., Mourani, P. M. & Abman, S. H., Aug 1 2017, In : American Journal of Respiratory and Critical Care Medicine. 196, 3, p. 364-374 11 p.

Research output: Contribution to journalArticle

34 Scopus citations
2016

Neurofibromin is a novel regulator of Ras-induced reactive oxygen species production in mice and humans

Bessler, W. K., Hudson, F. Z., Zhang, H., Harris, V., Wang, Y., Mund, J. A., Downing, B., Ingram, D. A., Case, J., Fulton, D. J. & Stansfield, B. K., Aug 1 2016, In : Free Radical Biology and Medicine. 97, p. 212-222 11 p.

Research output: Contribution to journalArticle

11 Scopus citations

Preclinical Evidence for the Use of Sunitinib Malate in the Treatment of Plexiform Neurofibromas

Ferguson, M. J., Rhodes, S. D., Jiang, L., Li, X., Yuan, J., Yang, X., Zhang, S., Vakili, S. T., Territo, P., Hutchins, G., Yang, F. C., Ingram, D. A., Clapp, D. W. & Chen, S., Feb 1 2016, In : Pediatric Blood and Cancer. 63, 2, p. 206-213 8 p.

Research output: Contribution to journalArticle

7 Scopus citations
2015

Brief report: Endothelial colony-forming cells and inflammatory monocytes in HIV

Hays, T. R., Mund, J. A., Liu, Z., Case, J., Ingram, D. A. & Gupta, S. K., Apr 15 2015, In : Journal of Acquired Immune Deficiency Syndromes. 68, 5, p. 550-553 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Early pulmonary vascular disease in preterm infants at risk for bronchopulmonary dysplasia

Mourani, P. M., Sontag, M. K., Younoszai, A., Miller, J. I., Kinsella, J. P., Baker, C. D., Poindexter, B. B., Ingram, D. A. & Abman, S. H., Jan 1 2015, In : American journal of respiratory and critical care medicine. 191, 1, p. 87-95 9 p.

Research output: Contribution to journalArticle

150 Scopus citations
5 Scopus citations

Lung parenchymal development in premature infants without bronchopulmonary dysplasia

Assaf, S. J., Chang, D. V., Tiller, C. J., Kisling, J. A., Case, J., Mund, J. A., Slaven, J. E., Yu, Z., Ahlfeld, S. K., Poindexter, B., Haneline, L. S., Ingram, D. A. & Tepper, R. S., Dec 1 2015, In : Pediatric pulmonology. 50, 12, p. 1313-1319 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Maturational Changes in Diastolic Longitudinal Myocardial Velocity in Preterm Infants

Di Maria, M. V., Younoszai, A. K., Sontag, M. K., Miller, J. I., Poindexter, B. B., Ingram, D. A., Abman, S. H. & Mourani, P. M., Sep 1 2015, In : Journal of the American Society of Echocardiography. 28, 9, p. 1045-1052 8 p., 3421.

Research output: Contribution to journalArticle

14 Scopus citations

Nf1+/- monocytes/macrophages induce neointima formation via CCR2 activation

Bessler, W. K., Kim, G., Hudson, F. Z., Mund, J. A., Mali, R., Menon, K., Kapur, R., Clapp, D. W., Ingram, D. A. & Stansfield, B. K., Aug 17 2015, In : Human molecular genetics. 25, 6, p. 1129-1139 11 p.

Research output: Contribution to journalArticle

7 Scopus citations
2014

CTF meeting 2012: Translation of the basic understanding of the biology and genetics of NF1, NF2, and schwannomatosis toward the development of effective therapies

Widemann, B. C., Acosta, M. T., Ammoun, S., Belzberg, A. J., Bernards, A., Blakeley, J., Bretscher, A., Cichowski, K., Clapp, D. W., Dombi, E., Evans, G. D., Ferner, R., Fernandez-Valle, C., Fisher, M. J., Giovannini, M., Gutmann, D. H., Hanemann, C. O., Hennigan, R., Huson, S., Ingram, D. & 19 others, Kissil, J., Korf, B. R., Legius, E., Packer, R. J., Mcclatchey, A. I., Mccormick, F., North, K., Pehrsson, M., Plotkin, S. R., Ramesh, V., Ratner, N., Schirmer, S., Sherman, L., Schorry, E., Stevenson, D., Stewart, D. R., Ullrich, N., Bakker, A. C. & Morrison, H., Mar 2014, In : American Journal of Medical Genetics, Part A. 164, 3, p. 563-578 16 p.

Research output: Contribution to journalArticle

17 Scopus citations

Membrane and capillary components of lung diffusion and pro-angiogenic cells in infants

Chang, D. V., Tiller, C. J., Kisling, J. A., Case, J., Mund, J. A., Haneline, L. S., Ingram, D. A. & Tepper, R. S., Feb 1 2014, In : European Respiratory Journal. 43, 2, p. 497-504 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Neurofibromin-deficient myeloid cells are critical mediators of aneurysm formation in vivo

Li, F., Downing, B. D., Smiley, L. C., Mund, J. A., DiStasi, M. R., Bessler, W. K., Sarchet, K. N., Hinds, D. M., Kamendulis, L. M., Hingtgen, C. M., Case, J., Clapp, D. W., Conway, S. J., Stansfield, B. K. & Ingram, D. A., Jan 1 2014, In : Circulation. 129, 11, p. 1213-1224 12 p.

Research output: Contribution to journalArticle

13 Scopus citations

Ras-mek-erk signaling regulates Nf1 heterozygous neointima formation

Stansfield, B. K., Bessler, W. K., Mali, R., Mund, J. A., Downing, B. D., Kapur, R. & Ingram, D. A., Jan 1 2014, In : American Journal of Pathology. 184, 1, p. 79-85 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2013

Heterozygous inactivation of the NF1 gene in myeloid cells enhances neointima formation via a rosuvastatin-sensitive cellular pathway

Stansfield, B. K., Bessler, W. K., Mali, R., Mund, J. A., Downing, B., Li, F., Sarchet, K. N., DiStasi, M. R., Conway, S. J., Kapur, R. & Ingram, D. A., Mar 1 2013, In : Human molecular genetics. 22, 5, p. 977-988 12 p., dds502.

Research output: Contribution to journalArticle

11 Scopus citations

Normal hematopoiesis and neurofibromin-deficient myeloproliferative disease require Erk

Staser, K., Park, S. J., Rhodes, S. D., Zeng, Y., He, Y. Z., Shew, M. A., Gehlhausen, J. R., Cerabona, D., Menon, K., Chen, S., Sun, Z., Yuan, J., Ingram, D. A., Nalepa, G., Yang, F. C. & Clapp, D. W., Jan 2 2013, In : Journal of Clinical Investigation. 123, 1, p. 329-334 6 p.

Research output: Contribution to journalArticle

29 Scopus citations
2012

Changes in the frequency and in vivo vessel-forming ability of rhesus monkey circulating endothelial colony-forming cells across the lifespan (birth to aged)

Shelley, W. C., Leapley, A. C., Huang, L., Critser, P. J., Zeng, P., Prater, D., Ingram, D. A., Tarantal, A. F. & Yoder, M. C., Feb 1 2012, In : Pediatric Research. 71, 2, p. 156-161 6 p.

Research output: Contribution to journalArticle

21 Scopus citations

Distinct contribution of human cord blood-derived endothelial colony forming cells to liver and gut in a fetal sheep model

Wood, J. A., Colletti, E., Mead, L. E., Ingram, D., Porada, C. D., Zanjani, E. D., Yoder, M. C. & Almeida-Porada, G., Sep 1 2012, In : Hepatology. 56, 3, p. 1086-1096 11 p.

Research output: Contribution to journalArticle

18 Scopus citations
88 Scopus citations

Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: A phase 2 trial

Robertson, K. A., Nalepa, G., Yang, F. C., Bowers, D. C., Ho, C. Y., Hutchins, G. D., Croop, J. M., Vik, T. A., Denne, S. C., Parada, L. F., Hingtgen, C. M., Walsh, L. E., Yu, M., Pradhan, K. R., Edwards-Brown, M. K., Cohen, M. D., Fletcher, J. W., Travers, J. B., Staser, K. W., Lee, M. W. & 5 others, Sherman, M. R., Davis, C. J., Miller, L. C., Ingram, D. A. & Clapp, D. W., Dec 1 2012, In : The Lancet Oncology. 13, 12, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

98 Scopus citations

Neurofibromatosis 2011: A report of the Children's Tumor Foundation Annual Meeting

Kalamarides, M., Acosta, M. T., Babovic-Vuksanovic, D., Carpen, O., Cichowski, K., Gareth Evans, D., Giancotti, F., Oliver Hanemann, C., Ingram, D., Lloyd, A. C., Mayes, D. A., Messiaen, L., Morrison, H., North, K., Packer, R., Pan, D., Stemmer-Rachamimov, A., Upadhyaya, M., Viskochil, D., Wallace, M. R. & 2 others, Hunter-Schaedle, K. & Ratner, N., Mar 1 2012, In : Acta Neuropathologica. 123, 3, p. 369-380 12 p.

Research output: Contribution to journalArticle

28 Scopus citations
2011

Differential mechanisms of X-ray-induced cell death in human endothelial progenitor cells Isolated from cord blood and adults

Mendonca, M. S., Chin-Sinex, H., Dhaemers, R., Mead, L. E., Yoder, M. C. & Ingram, D. A., Aug 1 2011, In : Radiation research. 176, 2, p. 208-216 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Expression of human papillomavirus type 16 E7 is sufficient to significantly increase expression of angiogenic factors but is not sufficient to induce endothelial cell migration

Walker, J., Smiley, L. C., Ingram, D. & Roman, A., Feb 20 2011, In : Virology. 410, 2, p. 283-290 8 p.

Research output: Contribution to journalArticle

15 Scopus citations
20 Scopus citations

Human endothelial colony forming cells undergo vasculogenesis within biphasic calcium phosphate bone tissue engineering constructs

Lan Levengood, S. K., Poellmann, M. J., Clark, S. G., Ingram, D. A., Yoder, M. C. & Wagoner Johnson, A. J., Dec 1 2011, In : Acta Biomaterialia. 7, 12, p. 4222-4228 7 p.

Research output: Contribution to journalArticle

21 Scopus citations

Kinase suppressor of ras (ksr1) modulates multiple kit-ligand-dependent mast cell functions

Chen, M., Burgin, S., Staser, K., He, Y., Li, X., Robinson, M., Jiang, L., Chan, R. J., Ingram, D. & Clapp, D. W., Oct 1 2011, In : Experimental Hematology. 39, 10, p. 969-976 8 p.

Research output: Contribution to journalArticle

5 Scopus citations

Polychromatic flow cytometry identifies novel subsets of circulating cells with angiogenic potential in pediatric solid tumors

Pradhan, K. R., Mund, J. A., Johnson, C., Vik, T. A., Ingram, D. A. & Case, J., Sep 1 2011, In : Cytometry Part B - Clinical Cytometry. 80 B, 5, p. 335-338 4 p.

Research output: Contribution to journalArticle

16 Scopus citations
2010

A hierarchy of endothelial colony-forming cell activity displayed by bovine corneal endothelial cells

Huang, L., Harkenrider, M., Thompson, M., Zeng, P., Tanaka, H., Gilley, D., Ingram, D. A., Bonanno, J. A. & Yoder, M. C., Aug 1 2010, In : Investigative Ophthalmology and Visual Science. 51, 8, p. 3943-3949 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

Application of polychromatic flow cytometry to identify novel subsets of circulating cells with angiogenic potential

Estes, M. L., Mund, J. A., Mead, L. E., Prater, D. N., Cai, S., Wang, H., Pollok, K. E., Murphy, M. P., An, C. S. T., Srour, E. F., Ingram, D. A. & Case, J., Sep 1 2010, In : Cytometry Part A. 77, 9, p. 831-839 9 p.

Research output: Contribution to journalArticle

59 Scopus citations

Bone marrow-derived angiogenic cells restore lung alveolar and vascular structure after neonatal hyperoxia in infant mice

Balasubramaniam, V., Ryan, S. L., Seedorf, G. J., Roth, E. V., Heumann, T. R., Yoder, M. C., Ingram, D. A., Hogan, C. J., Markham, N. E. & Abman, S. H., Mar 1 2010, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 298, 3, p. L315-L323

Research output: Contribution to journalArticle

79 Scopus citations

Endothelial abnormalities in adolescents with type 1 diabetes: A biomarker for vascular sequelae?

Dimeglio, L. A., Tosh, A., Saha, C., Estes, M., Mund, J., Mead, L. E., Lien, I., Ingram, D. A. & Haneline, L. S., Oct 1 2010, In : Journal of Pediatrics. 157, 4, p. 540-546 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Endothelial colony-forming cells and mesenchymal stem cells from ECMO circuits of term infants

Hoesli, S. J., Mead, L. E., Prater, D., Javed, M. J., Ingram, D. A. & Denne, S. C., Nov 1 2010, In : Journal of Perinatology. 30, 11, p. 724-730 7 p.

Research output: Contribution to journalArticle

8 Scopus citations

Genetic and cellular evidence of vascular inflammation in neurofibromin-deficient mice and humans

Lasater, E. A., Li, F., Bessler, W. K., Estes, M. L., Vemula, S., Hingtgen, C. M., Dinauer, M. C., Kapur, R., Conway, S. J. & Ingram, D. A., Mar 1 2010, In : Journal of Clinical Investigation. 120, 3, p. 859-870 12 p.

Research output: Contribution to journalArticle

48 Scopus citations
2009

Endothelial colony-forming cells from preterm infants are increased and more susceptible to hyperoxia

Baker, C. D., Ryan, S. L., Ingram, D. A., Seedorf, G. J., Abman, S. H. & Balasubramaniam, V., Sep 1 2009, In : American journal of respiratory and critical care medicine. 180, 5, p. 454-461 8 p.

Research output: Contribution to journalArticle

78 Scopus citations

P21-activated kinase regulates mast cell degranulation via effects on calcium mobilization and cytoskeletal dynamics

Allen, J. D., Jaffer, Z. M., Park, S. J., Burgin, S., Hofmann, C., Sells, M. A., Chen, S., Derr-Yellin, E., Michels, E. G., McDaniel, A., Bessler, W. K., Ingram, D. A., Atkinson, S. J., Travers, J. B., Chernoff, J. & Clapp, D. W., Mar 19 2009, In : Blood. 113, 12, p. 2695-2705 11 p.

Research output: Contribution to journalArticle

84 Scopus citations
101 Scopus citations

Ras dependent paracrine secretion of osteopontin by nf1 +/- osteoblasts promote osteodast activation in a neurofibromatosis type i murine model

Li, H., Liu, Y., Zhang, Q., Jing, Y., Chen, S., Song, Z., Yan, J., Li, Y., Wu, X., Zhang, X., Zhang, Y., Case, J., Yu, M., Ingram, D. A. & Yang, F. C., Jun 1 2009, In : Pediatric Research. 65, 6, p. 613-618 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Release of proinflammatory mediators and expression of proinflammatory adhesion molecules by endothelial progenitor cells

Zhang, Y., Ingram, D. A., Murphy, M. P., Saadatzadeh, M. R., Mead, L. E., Prater, D. N. & Rehman, J., May 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 5, p. H1675-H1682

Research output: Contribution to journalArticle

88 Scopus citations

Robust functional vascular network formation in vivo by cooperation of adipose progenitor and endothelial cells

Traktuev, D. O., Prater, D. N., Merfeld-Clauss, S., Sanjeevaiah, A. R., Saadatzadeh, M. R., Murphy, M., Johnstone, B. H., Ingram, D. A. & March, K. L., Jun 19 2009, In : Circulation research. 104, 12, p. 1410-1420 11 p.

Research output: Contribution to journalArticle

240 Scopus citations

Suppressed hindlimb perfusion in Rac2 -/-and Nox2 -/- mice does not result from impaired collateral growth

Distasi, M. R., Case, J., Ziegler, M. A., Dinauer, M. C., Yoder, M. C., Haneline, L. S., Dalsing, M. C., Miller, S. J., Labarrere, C. A., Murphy, M. P., Ingram, D. A. & Unthank, J. L., Mar 1 2009, In : American Journal of Physiology - Heart and Circulatory Physiology. 296, 3, p. H877-H886

Research output: Contribution to journalArticle

22 Scopus citations
2008

Endothelial colony forming cells and mesenchymal stem cells are enriched at different gestational ages in human umbilical cord blood

Javed, M. J., Mead, L. E., Prater, D., Bessler, W. K., Foster, D., Case, J., Goebel, W. S., Yoder, M. C., Haneline, L. S. & Ingram, D. A., Jul 1 2008, In : Pediatric Research. 64, 1, p. 68-73 6 p.

Research output: Contribution to journalArticle

77 Scopus citations

Generation and characterization of Csrp1 enhancer-driven tissue-restricted Cre-recombinase mice

Snider, P., Fix, J. L., Rogers, R., Peabody-Dowling, G., Ingram, D., Lilly, B. & Conway, S. J., Mar 1 2008, In : Genesis. 46, 3, p. 167-176 10 p.

Research output: Contribution to journalArticle

6 Scopus citations

In vitro hyperglycemia or a diabetic intrauterine environment reduces neonatal endothelial colony-forming cell numbers and function

Ingram, D. A., Lien, I. Z., Mead, L. E., Estes, M., Prater, D. N., Derr-Yellin, E., Dimeglio, L. A. & Haneline, L. S., Mar 1 2008, In : Diabetes. 57, 3, p. 724-731 8 p.

Research output: Contribution to journalArticle

109 Scopus citations

Nf1+/- mice have increased neointima formation via hyperactivation of a Gleevec sensitive molecular pathway

Lasater, E. A., Bessler, W. K., Mead, L. E., Horn, W. E., Clapp, D. W., Conway, S. J., Ingram, D. A. & Li, F., Aug 1 2008, In : Human molecular genetics. 17, 15, p. 2336-2344 9 p.

Research output: Contribution to journalArticle

52 Scopus citations

Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/-- and c-kit-Dependent Bone Marrow

Yang, F. C., Ingram, D. A., Chen, S., Zhu, Y., Yuan, J., Li, X., Yang, X., Knowles, S., Horn, W., Li, Y., Zhang, S., Yang, Y., Vakili, S. T., Yu, M., Burns, D., Robertson, K., Hutchins, G., Parada, L. F. & Clapp, D. W., Oct 31 2008, In : Cell. 135, 3, p. 437-448 12 p.

Research output: Contribution to journalArticle

232 Scopus citations

Pak1 regulates multiple c-Kit mediated Ras-MAPK gain-in-function phenotypes in Nf1+/ mast cells

McDaniel, A. S., Allen, J. D., Park, S. J., Jaffer, Z. M., Michels, E. G., Burgin, S. J., Chen, S., Bessler, W. K., Hofmann, C., Ingram, D. A., Chernoff, J. & Clapp, D. W., Dec 1 2008, In : Blood. 112, 12, p. 4646-4654 9 p.

Research output: Contribution to journalArticle

61 Scopus citations

Periostin is required for maturation and extracellular matrix stabilization of noncardiomyocyte lineages of the heart

Snider, P., Hinton, R. B., Moreno-Rodriguez, R. A., Wang, J., Rogers, R., Lindsley, A., Li, F., Ingram, D. A., Menick, D., Field, L., Firulli, A. B., Molkentin, J. D., Markwald, R. & Conway, S. J., Apr 1 2008, In : Circulation research. 102, 7, p. 752-760 9 p.

Research output: Contribution to journalArticle

213 Scopus citations
63 Scopus citations
2007

Acute myocardial infarction in swine rapidly and selectively releases highly proliferative endothelial colony forming cells (ECFCs) into circulation

Huang, L., Hou, D., Thompson, M. A., Baysden, S. E., Shelley, W. C., Ingram, D. A., March, K. L. & Yoder, M. C., Dec 1 2007, In : Cell Transplantation. 16, 9, p. 887-897 11 p.

Research output: Contribution to journalArticle

35 Scopus citations