Diane Janowicz

  • 525 Citations
  • 15 h-Index
20042019

Research output per year

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Publications

  • 525 Citations
  • 15 h-Index
  • 28 Article
  • 2 Chapter
  • 1 Letter
  • 1 Review article
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Article

A (p)ppGpp-null mutant of Haemophilus ducreyi is partially attenuated in humans due to multiple conflicting phenotypes

Holley, C., Gangaiah, D., Li, W., Fortney, K. R., Janowicz, D. M., Ellinger, S., Zwickl, B., Katz, B. P. & Spinola, S. M., 2014, In : Infection and immunity. 82, 8, p. 3492-3502 11 p.

Research output: Contribution to journalArticle

6 Scopus citations

A Class I Haemophilus ducreyi Strain Containing a Class II hgbA Allele Is Partially Attenuated in Humans: Implications for HGBA vaccine efficacy trials

Leduc, I., Fortney, K. R., Janowicz, D. M., Zwickl, B., Ellinger, S., Katz, B. P., Lin, H., Dong, Q. & Spinola, S. M., Jan 1 2019, In : Infection and immunity. 87, 7, e00112.

Research output: Contribution to journalArticle

Activation of the CpxRA system by deletion of cpxA impairs the ability of Haemophilus ducreyi to infect humans

Spinola, S. M., Fortney, K. R., Baker, B., Janowicz, D. M., Zwickl, B., Katz, B. P., Blick, R. J. & Munson, R. S., Sep 1 2010, In : Infection and immunity. 78, 9, p. 3898-3904 7 p.

Research output: Contribution to journalArticle

38 Scopus citations

A DltA mutant of Haemophilus ducreyi is partially attenuated in its ability to cause pustules in human volunteers

Janowicz, D., Leduc, I., Fortney, K. R., Katz, B. P., Elkins, C. & Spinola, S. M., Feb 1 2006, In : Infection and immunity. 74, 2, p. 1394-1397 4 p.

Research output: Contribution to journalArticle

19 Scopus citations

A fibrinogen-binding lipoprotein contributes to the virulence of Haemophilus ducreyi in humans

Bauer, M. E., Townsend, C. A., Doster, R. S., Fortney, K. R., Zwickl, B. W., Katz, B. P., Spinola, S. M. & Janowicz, D. M., Mar 1 2009, In : Journal of Infectious Diseases. 199, 5, p. 684-692 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

A Haemophilus ducreyi CpxR deletion mutant is virulent in human volunteers

Labandeira-Rey, M., Dodd, D., Fortney, K. R., Zwickl, B., Katz, B. P., Janowicz, D. M., Spinola, S. M. & Hansen, E. J., Jun 15 2011, In : Journal of Infectious Diseases. 203, 12, p. 1859-1865 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Carbon storage regulator a contributes to the virulence of haemophilus ducreyi in humans by multiple mechanisms

Gangaiah, D., Li, W., Fortney, K. R., Janowicz, D. M., Ellinger, S., Zwickl, B., Katz, B. P. & Spinola, S. M., Feb 1 2013, In : Infection and immunity. 81, 2, p. 608-617 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Determination of an interaction network between an extracellular bacterial pathogen and the human host

Griesenauer, B., Tran, T. M., Fortney, K. R., Janowicz, D. M., Johnson, P., Gao, H., Barnes, S., Wilson, L. S., Liu, Y. & Spinola, S. M., May 1 2019, In : mBio. 10, 3, e01193-19.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

DksA and (p)ppGpp have unique and overlapping contributions to Haemophilus ducreyi pathogenesis in humans

Holley, C. L., Zhang, X., Fortney, K. R., Ellinger, S., Johnson, P., Baker, B., Liu, Y., Janowicz, D. M., Katz, B. P., Munson, R. S. & Spinola, S. M., Jan 1 2015, In : Infection and immunity. 83, 8, p. 3281-3292 12 p.

Research output: Contribution to journalArticle

12 Scopus citations

Dysregulated immune profiles for skin and dendritic cells are associated with increased host susceptibility to Haemophilus ducreyi infection in human volunteers

Humphreys, T. L., Li, L., Li, X., Janowicz, D. M., Fortney, K. R., Zhao, Q., Li, W., McClintick, J., Katz, B. P., Wilkes, D. S., Edenberg, H. J. & Spinola, S. M., Dec 1 2007, In : Infection and immunity. 75, 12, p. 5686-5697 12 p.

Research output: Contribution to journalArticle

20 Scopus citations
56 Scopus citations

Experimental infection with Haemophilus ducreyi in persons who are infected with HIV does not cause local or augment systemic viral replication

Janowicz, D. M., Tenner-Racz, K., Racz, P., Humphreys, T. L., Schnizlein-Bick, C., Fortney, K. R., Zwickl, B., Katz, B. P., Campbell, J. J., Ho, D. D. & Spinola, S. M., May 15 2007, In : Journal of Infectious Diseases. 195, 10, p. 1443-1451 9 p.

Research output: Contribution to journalArticle

11 Scopus citations

Expression of Haemophilus ducreyi collagen binding outer membrane protein NcaA is required for virulence in swine and human challenge models of chancroid

Fulcher, R. A., Cole, L. E., Janowicz, D. M., Toffer, K. L., Fortney, K. R., Katz, B. P., Orndorff, P. E., Spinola, S. M. & Kawula, T. H., May 1 2006, In : Infection and immunity. 74, 5, p. 2651-2658 8 p.

Research output: Contribution to journalArticle

28 Scopus citations

Expression of OmpP2A and OmpP2B is not required for pustule formation by Haemophilus ducreyi in human volunteers

Janowicz, D., Luke, N. R., Fortney, K. R., Katz, B. P., Campagnari, A. A. & Spinola, S. M., Mar 1 2006, In : Microbial Pathogenesis. 40, 3, p. 110-115 6 p.

Research output: Contribution to journalArticle

13 Scopus citations

Expression of the Flp proteins by Haemophilus ducreyi is necessary for virulence in human volunteers

Janowicz, D. M., Cooney, S. A., Walsh, J., Baker, B., Katz, B. P., Fortney, K. R., Zwickl, B. W., Ellinger, S. & Munson, R. S., Oct 3 2011, In : BMC Microbiology. 11, 208.

Research output: Contribution to journalArticle

15 Scopus citations

Expression of the LspA1 and LspA2 proteins by Haemophilus ducreyi is required for virulence in human volunteers

Janowicz, D. M., Fortney, K. R., Katz, B. P., Latimer, J. L., Deng, K., Hansen, E. J. & Spinola, S. M., Aug 1 2004, In : Infection and immunity. 72, 8, p. 4528-4533 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Haemophilus ducreyi Hfq contributes to virulence gene regulation as cells enter stationary phase

Gangaiah, D., Labandeira-Rey, M., Zhang, X., Fortney, K. R., Ellinger, S., Zwickl, B., Baker, B., Liu, Y., Janowicz, D. M., Katz, B. P., Brautigam, C. A., Munson, R. S., Hansen, E. J. & Spinola, S. M., Feb 11 2014, In : mBio. 5, 1, e01081-13.

Research output: Contribution to journalArticle

8 Scopus citations

Haemophilus ducreyi SapA contributes to cathelicidin resistance and virulence in humans

Mount, K. L. B., Townsend, C. A., Rinker, S. D., Gu, X., Fortney, K. R., Zwickl, B. W., Janowicz, D. M., Spinola, S. M., Katz, B. P. & Bauer, M. E., Mar 1 2010, In : Infection and immunity. 78, 3, p. 1176-1184 9 p.

Research output: Contribution to journalArticle

23 Scopus citations

HIV transmission and injection drug use: Lessons from the Indiana outbreak

Janowicz, D. M., Jul 1 2016, In : Topics in antiviral medicine. 24, 2, p. 90-92 3 p.

Research output: Contribution to journalArticle

9 Scopus citations

Identification of Haemophilus ducreyi genes expressed during human infection

Bauer, M. E., Fortney, K. R., Harrison, A., Janowicz, D. M., Munson, R. S. & Spinola, S. M., Apr 1 2008, In : Microbiology. 154, 4, p. 1152-1160 9 p.

Research output: Contribution to journalArticle

24 Scopus citations

Inactivation of the haemophilus ducreyi luxS gene affects the virulence of this pathogen in human subjects

Labandeira-Rey, M., Janowicz, D. M., Blick, R. J., Fortney, K. R., Zwickl, B., Katz, B. P., Spinola, S. M. & Hansen, E. J., Aug 1 2009, In : Journal of Infectious Diseases. 200, 3, p. 409-416 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Mechanism of human natural killer cell activation by haemophilus ducreyi

Li, W., Janowicz, D. M., Fortney, K. R., Katz, B. P. & Spinola, S. M., Aug 15 2009, In : Journal of Infectious Diseases. 200, 4, p. 590-598 9 p.

Research output: Contribution to journalArticle

17 Scopus citations

Outer membrane protein P4 is not required for virulence in the human challenge model of Haemophilus ducreyi infection

Janowicz, D. M., Zwickl, B. W., Fortney, K. R., Katz, B. P. & Bauer, M. E., Jun 24 2014, In : BMC Microbiology. 14, 1, 166.

Research output: Contribution to journalArticle

1 Scopus citations

Permeases of the sap transporter are required for cathelicidin resistance and virulence of haemophilus ducreyi in humans

Rinker, S. D., Gu, X., Fortney, K. R., Zwickl, B. W., Katz, B. P., Janowicz, D. M., Spinola, S. M. & Bauer, M. E., Nov 1 2012, In : Journal of Infectious Diseases. 206, 9, p. 1407-1414 8 p.

Research output: Contribution to journalArticle

12 Scopus citations

Phosphoethanolamine transferase LptA in haemophilus ducreyi modifies lipid a and contributes to human defensin resistance in vitro

Trombley, M. P., Post, D. M. B., Rinker, S. D., Reinders, L. M., Fortney, K. R., Zwickl, B. W., Janowicz, D. M., Baye, F. M., Katz, B. P., Spinola, S. M. & Bauer, M. E., Apr 22 2015, In : PLoS ONE. 10, 4, e0124373.

Research output: Contribution to journalArticle

8 Scopus citations

Role played by CD4+FOXP3+ regulatory T cells in suppression of host responses to Haemophilus ducreyi during experimental infection of human volunteers

Li, W., Tenner-Racz, K., Racz, P., Janowicz, D. M., Fortney, K. R., Katz, B. P. & Spinola, S. M., Jun 15 2010, In : Journal of Infectious Diseases. 201, 12, p. 1839-1848 10 p.

Research output: Contribution to journalArticle

11 Scopus citations

Sialylation of lipooligosaccharides is dispensable for the virulence of haemophilus ducreyi in humans

Spinola, S. M., Li, W., Fortney, K. R., Janowicz, D. M., Zwickl, B., Katz, B. P. & Munson, R. S., Feb 1 2012, In : Infection and immunity. 80, 2, p. 679-687 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

The human skin microbiome associates with the outcome of and is influenced by bacterial infection

Van Rensburg, J. J., Lin, H., Gao, X., Toh, E., Fortney, K. R., Ellinger, S., Zwickl, B., Janowicz, D., Katz, B., Nelson, D. E., Dong, Q. & Spinolaa, S. M., 2015, In : mBio. 6, 5, e01315-15.

Research output: Contribution to journalArticle

47 Scopus citations