Elliot Rosen

  • 3040 Citations
  • 27 h-Index
1979 …2013

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

2013

Fibrin Networks Regulate Protein Transport during Thrombus Development

Kim, O. V., Xu, Z., Rosen, E. D. & Alber, M. S., Jun 1 2013, In : PLoS computational biology. 9, 6, e1003095.

Research output: Contribution to journalArticle

27 Scopus citations
2012

Automatic segmentation and analysis of fibrin networks in 3D confocal microscopy images

Liu, X., Mu, J., Machlus, K. R., Wolberg, A. S., Rosen, E. D., Xu, Z., Alber, M. S. & Chen, D. Z., May 14 2012, Medical Imaging 2012: Image Processing. 831439. (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; vol. 8314).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Scopus citations

Mechano-rheological properties of the murine thrombus determined via nanoindentation and finite element modeling

Slaboch, C. L., Alber, M. S., Rosen, E. D. & Ovaert, T. C., Jun 1 2012, In : Journal of the Mechanical Behavior of Biomedical Materials. 10, p. 75-86 12 p.

Research output: Contribution to journalArticle

17 Scopus citations

Multiscale Model of Fibrin Accumulation on the Blood Clot Surface and Platelet Dynamics

Xu, Z., Christley, S., Lioi, J., Kim, O., Harvey, C., Sun, W., Rosen, E. D. & Alber, M., 2012, Methods in Cell Biology. Academic Press Inc., p. 367-388 22 p. (Methods in Cell Biology; vol. 110).

Research output: Chapter in Book/Report/Conference proceedingChapter

23 Scopus citations

Multiscale models of thrombogenesis

Xu, Z., Kim, O., Kamocka, M., Rosen, E. D. & Alber, M., Apr 23 2012, In : Wiley Interdisciplinary Reviews: Systems Biology and Medicine. 4, 3, p. 237-246 10 p.

Research output: Contribution to journalArticle

24 Scopus citations
2011

Computational approaches to studying thrombus development

Xu, Z., Kamocka, M., Alber, M. & Rosen, E. D., Mar 1 2011, In : Arteriosclerosis, thrombosis, and vascular biology. 31, 3, p. 500-505 6 p.

Research output: Contribution to journalArticle

47 Scopus citations

Correlation between fibrin network structure and mechanical properties: An experimental and computational analysis

Kim, E., Kim, O. V., MacHlus, K. R., Liu, X., Kupaev, T., Lioi, J., Wolberg, A. S., Chen, D. Z., Rosen, E. D., Xu, Z. & Alber, M., May 21 2011, In : Soft Matter. 7, 10, p. 4983-4992 10 p.

Research output: Contribution to journalArticle

31 Scopus citations

Modelling platelet-blood flow interaction using the subcellular element Langevin method

Sweet, C. R., Chatterjee, S., Xu, Z., Bisordi, K., Rosen, E. D. & Alber, M., Dec 7 2011, In : Journal of the Royal Society Interface. 8, 65, p. 1760-1771 12 p.

Research output: Contribution to journalArticle

27 Scopus citations

Pro-inflammatory angiogenesis is mediated by p38 MAP kinase.

Rajashekhar, G., Kamocka, M., Marin, A., Suckow, M. A., Wolter, W. R., Badve, S., Sanjeevaiah, A. R., Pumiglia, K., Rosen, E. & Clauss, M., Mar 2011, In : Journal of cellular physiology. 226, 3, p. 800-808 9 p.

Research output: Contribution to journalArticle

32 Scopus citations
2010

A multiscale model of venous thrombus formation with surface-mediated control of blood coagulation cascade

Xu, Z., Lioi, J., Mu, J., Kamocka, M. M., Liu, X., Chen, D. Z., Rosen, E. D. & Alber, M., May 5 2010, In : Biophysical journal. 98, 9, p. 1723-1732 10 p.

Research output: Contribution to journalArticle

88 Scopus citations

Erratum: A multiscale model of venous thrombus formation with surface-mediated control of blood coagulation cascade (Biophysical Journal (2010) 98 (1723-1732))

Xu, Z., Lioi, J., Mu, J., Kamocka, M. M., Liu, X., Chen, D. Z., Rosen, E. D. & Alber, M., Oct 6 2010, In : Biophysical Journal. 99, 7, p. 2384-2385 2 p.

Research output: Contribution to journalComment/debate

1 Scopus citations

Segmentation, reconstruction, and analysis of blood thrombus formation in 3D 2-photon microscopy images

Mu, J., Liu, X., Kamocka, M. M., Xu, Z., Alber, M. S., Rosen, E. D. & Chen, D. Z., Dec 1 2010, In : Eurasip Journal on Advances in Signal Processing. 2010, 147216.

Research output: Contribution to journalArticle

10 Scopus citations

Two-photon intravital imaging of thrombus development

Kamocka, M. M., Mu, J., Liu, X., Chen, N., Zollman, A., Sturonas-Brown, B., Dunn, K., Xu, Z., Chen, D. Z., Alber, M. S. & Rosen, E. D., Dec 1 2010, In : Journal of Biomedical Optics. 15, 1, 016020.

Research output: Contribution to journalArticle

42 Scopus citations
2009

Combined experimental and simulation study of blood clot formation

Xu, Z., Lioi, J., Alber, M., Mu, J., Liu, X., Chen, D. Z., Kamocka, M. M. & Rosen, E. D., Dec 1 2009, TIC-STH'09: 2009 IEEE Toronto International Conference - Science and Technology for Humanity. p. 357-362 6 p. 5444476. (TIC-STH'09: 2009 IEEE Toronto International Conference - Science and Technology for Humanity).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

8 Scopus citations

Segmentation, reconstruction, and analysis of blood thrombi in 2-photon microscopy images

Mu, J., Liu, X., Kamocka, M. M., Xu, Z., Alber, M. S., Rosen, E. D. & Chen, D. Z., Nov 23 2009, 2009 22nd IEEE International Symposium on Computer-Based Medical Systems, CBMS 2009. 5255347. (Proceedings - IEEE Symposium on Computer-Based Medical Systems).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

6 Scopus citations

Study of blood flow impact on growth of thrombi using a multiscale model

Xu, Z., Chen, N., Shadden, S. C., Marsden, J. E., Kamocka, M. M., Rosen, E. D. & Alber, M., Feb 18 2009, In : Soft Matter. 5, 4, p. 769-779 11 p.

Research output: Contribution to journalArticle

81 Scopus citations
2008

A multiscale model of thrombus development

Xu, Z., Chen, N., Kamocka, M. M., Rosen, E. D. & Alber, M., Jul 6 2008, In : Journal of the Royal Society Interface. 5, 24, p. 705-722 18 p.

Research output: Contribution to journalArticle

121 Scopus citations

Identifying and genotyping transgene integration loci

Liang, Z., Breman, A. M., Grimes, B. R. & Rosen, E. D., Oct 1 2008, In : Transgenic Research. 17, 5, p. 979-983 5 p.

Research output: Contribution to journalArticle

15 Scopus citations

IFATS collection: Adipose stromal cell differentiation is reduced by endothelial cell contact and paracrine communication: Role of canonical Wnt signaling

Rajashekhar, G., Traktuev, D. O., Roell, W. C., Johnstone, B. H., Merfeld-Clauss, S., Van Natta, B., Rosen, E. D., March, K. L. & Clauss, M., Oct 1 2008, In : STEM CELLS. 26, 10, p. 2674-2681 8 p.

Research output: Contribution to journalArticle

77 Scopus citations

Rat prostate tumors express cancer procoagulant, an activator of coagulation factor X

Kamocka, M., Pollard, M., Suckow, M., Mielicki, W. P. & Rosen, E. D., Jun 1 2008, In : Comparative medicine. 58, 3, p. 282-286 5 p.

Research output: Contribution to journalArticle

1 Scopus citations
2007
1 Scopus citations

In utero as a potential location for cell transplantation

Suckow, M. A. & Rosen, E. D., Oct 3 2007, In : Journal of Organ Dysfunction. 3, 3, p. 143-149 7 p.

Research output: Contribution to journalArticle

Prevention of human PC-346C prostate cancer growth in mice by a xenogeneic tissue vaccine

Suckow, M. A., Rosen, E. D., Wolter, W. R., Sailes, V., Jeffrey, R. & Tenniswood, M., Aug 1 2007, In : Cancer Immunology, Immunotherapy. 56, 8, p. 1275-1283 9 p.

Research output: Contribution to journalArticle

15 Scopus citations

Suppression of hepatocyte growth factor production impairs the ability of adipose-derived stem cells to promote ischemic tissue revascularization

Cai, L., Johnstone, B. H., Cook, T. G., Liang, Z., Traktuev, D., Cornetta, K., Ingram, D. A., Rosen, E. D. & March, K. L., Dec 1 2007, In : STEM CELLS. 25, 12, p. 3234-3243 10 p.

Research output: Contribution to journalArticle

158 Scopus citations

Tissue vaccines for cancer

Suckow, M. A., Heinrich, J. & Rosen, E. D., Dec 1 2007, In : Expert Review of Vaccines. 6, 6, p. 925-937 13 p.

Research output: Contribution to journalReview article

5 Scopus citations

Vaccination against prostate cancer using a live tissue factor deficient cell line in Lobund-Wistar rats

Heinrich, J. E., Pollard, M., Wolter, W. A., Liang, Z., Song, H., Rosen, E. D. & Suckow, M. A., May 1 2007, In : Cancer Immunology, Immunotherapy. 56, 5, p. 725-730 6 p.

Research output: Contribution to journalArticle

2 Scopus citations
2006
5 Scopus citations
2005

Generation of genetically-altered mice producing very low levels of coagulation factor VII

Rosen, E. D., Xu, H., Liang, Z., Martin, A. J., Suckow, M. & Castellino, F. J., Sep 1 2005, In : Thrombosis and Haemostasis. 94, 3, p. 493-497 5 p.

Research output: Contribution to journalArticle

34 Scopus citations

Mice with a severe deficiency in protein C display prothrombotic and proinflammatory phenotypes and compromised maternal reproductive capabilities

Lay, A. J., Liang, Z., Rosen, E. D. & Castellino, F. J., Jun 1 2005, In : Journal of Clinical Investigation. 115, 6, p. 1552-1561 10 p.

Research output: Contribution to journalArticle

60 Scopus citations

Tissue distribution of fetal liver cells following in utero transplantation in mice

Suckow, M. A., Zollman, A., Cornelissen, I., Casad, M., Roahrig, J., Castellino, F. J. & Rosen, E. D., Dec 2005, In : Experimental Biology and Medicine. 230, 11, p. 860-864 5 p.

Research output: Contribution to journalArticle

2 Scopus citations
2003

Activated protein C blocks p53-mediated apoptosis in ischemic human brain endothelium and is neuroprotective

Cheng, T., Liu, D., Griffin, J. H., Fernández, J. A., Castellino, F., Rosen, E. D., Fukudome, K. & Zlokovic, B. V., Mar 1 2003, In : Nature Medicine. 9, 3, p. 338-342 5 p.

Research output: Contribution to journalArticle

486 Scopus citations

In utero transplantation of wild-type fetal liver cells rescues factor X-deficient mice from fatal neonatal bleeding diatheses

Rosen, E. D., Cornelissen, I., Liang, Z., Zollman, A., Casad, M., Roahrig, J., Suckow, M. & Castellino, F. J., Jan 1 2003, In : Journal of Thrombosis and Haemostasis. 1, 1, p. 19-27 9 p.

Research output: Contribution to journalArticle

17 Scopus citations
2002

FXI is essential for thrombus formation following FeCl3-induced injury of the carotid artery in the mouse

Rosen, E. D., Gailani, D. & Castellino, F. J., Apr 23 2002, In : Thrombosis and Haemostasis. 87, 4, p. 774-776 3 p.

Research output: Contribution to journalLetter

107 Scopus citations

Gene targeting in hemostasis. Factor X.

Rosen, E. D., Sep 1 2002, In : Frontiers in bioscience : a journal and virtual library. 7, p. d1915-1925

Research output: Contribution to journalReview article

12 Scopus citations

Mice with a severe deficiency of the endothelial Protein C receptor gene develop, survive, and reproduce normally, and do not present with enhanced arterial thrombosis after challenge

Castellino, F. J., Liang, Z., Volkir, S. P., Haalboom, E., Martin, J. A., Sandoval-Cooper, M. J. & Rosen, E. D., Sep 1 2002, In : Thrombosis and Haemostasis. 88, 3, p. 462-472 11 p.

Research output: Contribution to journalArticle

44 Scopus citations

Tissue factor deficiency causes cardiac fibrosis and left ventricular dysfunction

Pawlinski, R., Fernandes, A., Kehrle, B., Pedersen, B., Parry, G., Erlich, J., Pyo, R., Gutstein, D., Zhang, J., Castellino, F., Melis, E., Carmeliet, P., Baretton, G., Luther, T., Taubman, M., Rosen, E. & Mackman, N., Nov 26 2002, In : Proceedings of the National Academy of Sciences of the United States of America. 99, 24, p. 15333-15338 6 p.

Research output: Contribution to journalArticle

86 Scopus citations
2001

Development of pulmonary fibrosis in fibrinogen-deficient mice

Wilberding, J. A., Ploplis, V. A., McLennan, L., Liang, Z., Cornelissen, I., Feldman, M., Deford, M. E., Rosen, E. D. & Castellino, F. J., Jan 1 2001, In : Annals of the New York Academy of Sciences. 936, p. 542-548 7 p.

Research output: Contribution to journalArticle

35 Scopus citations

Laser-induced noninvasive vascular injury models in mice generate platelet- and coagulationdependent thrombi

Rosen, E. D., Raymond, S., Zollman, A., Noria, F., Sandoval-Cooper, M., Shulman, A., Merz, J. L. & Castellino, F. J., Jan 1 2001, In : American Journal of Pathology. 158, 5, p. 1613-1622 10 p.

Research output: Contribution to journalArticle

114 Scopus citations

The characterization of mice with a targeted combined deficiency of protein C and factor XI

Chan, J. C. Y., Ganopolsky, J. G., Cornelissen, I., Suckow, M. A., Sandoval-Cooper, M. J., Brown, E. C., Noria, F., Gailani, D., Rosen, E. D., Ploplis, V. A. & Castellino, F. J., Feb 2001, In : American Journal of Pathology. 158, 2, p. 469-479 11 p.

Research output: Contribution to journalArticle

31 Scopus citations
2000

A total fibrinogen deficiency is compatible with the development of bleomycininduced pulmonary fibrosis in mice

Ploplis, V. A., Wilberding, J., Cornelissen, I., Defokdm, E., Uang, Z., Rosen, E. D. & Castellino, F. J., Dec 1 2000, In : Fibrinolysis and Proteolysis. 14, SUPPL. 1, 1 p.

Research output: Contribution to journalArticle

A total fibrinogen deficiency is compatible with the development of pulmonary fibrosis in mice

Ploplis, V. A., Wilberding, J., McLennan, L., Liang, Z., Cornelissen, I., Deford, M. E., Rosen, E. D. & Castellino, F. J., Jan 1 2000, In : American Journal of Pathology. 157, 3, p. 703-708 6 p.

Research output: Contribution to journalArticle

69 Scopus citations

Blood coagulation factor X deficiency causes partial embryonic lethality and fatal neonatal bleeding in mice

Dewerchin, M., Liang, Z., Moons, L., Carmeliet, P., Castellino, F. J., Collen, D. & Rosen, E. D., Feb 23 2000, In : Thrombosis and Haemostasis. 83, 2, p. 185-190 6 p.

Research output: Contribution to journalArticle

123 Scopus citations

Cloning and characterization of the murine coagulation factor X gene

Cooper, A., Liang, Z., Castellino, F. J. & Rosen, E. D., May 19 2000, In : Thrombosis and Haemostasis. 83, 5, p. 732-735 4 p.

Research output: Contribution to journalArticle

4 Scopus citations

Conditional rescue of fvti deficiency using gene targeted insertion of the tta-tetracycline genetic switch

Rosen, E. D., Dec 1 2000, In : Blood. 96, 11 PART I, p. 258a

Research output: Contribution to journalArticle

1999

Factor VII deficiency rescues the intrauterine lethality in mice associated with a tissue factor pathway inhibitor deficit

Chan, J. C. Y., Carmeliet, P., Moons, L., Rosen, E. D., Huang, Z. F., Broze, G. J., Collen, D. & Castellino, F. J., Feb 1999, In : Journal of Clinical Investigation. 103, 4, p. 475-482 8 p.

Research output: Contribution to journalArticle

Open Access
39 Scopus citations

Nucleotide structure and characterization of the murine gene encoding the endothelial cell protein C receptor

Liang, Z., Rosen, E. D. & Castellino, F. J., Jan 1 1999, In : Thrombosis and Haemostasis. 81, 4, p. 585-588 4 p.

Research output: Contribution to journalArticle

12 Scopus citations
1998

Characterization of transcriptional regulatory elements in the promoter region of the murine blood coagulation factor VII gene

Stauffer, D. R., Chukwumezie, B. N., Wilberding, J. A., Rosen, E. D. & Castellino, F. J., Jan 23 1998, In : Journal of Biological Chemistry. 273, 4, p. 2277-2287 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Chromosomal arrangement of the murine coagulation factor VII and factor X genes [6]

Liang, Z., Cooper, A., Rosen, E. D. & Castellino, F. J., Oct 7 1998, In : Thrombosis and Haemostasis. 80, 3, p. 524-525 2 p.

Research output: Contribution to journalLetter

5 Scopus citations

Cloning and characterization of a cDNA encoding murine coagulation factor X

Liang, Z., Cooper, A., DeFord, M. E., Carmeliet, P., Collen, D., Castellino, F. J. & Rosen, E. D., Jul 1 1998, In : Thrombosis and Haemostasis. 80, 1, p. 87-91 5 p.

Research output: Contribution to journalArticle

9 Scopus citations

Inactivation of the gene for anticoagulant protein C causes lethal perinatal consumptive coagulopathy in mice

Jalbert, L. R., Rosen, E. D., Moons, L., Chan, J. C. Y., Carmeliet, P., Collen, D. & Castellino, F. J., Oct 15 1998, In : Journal of Clinical Investigation. 102, 8, p. 1481-1488 8 p.

Research output: Contribution to journalArticle

Open Access
133 Scopus citations