G. David Roodman

  • 23227 Citations
  • 80 h-Index
1975 …2020
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Publications 1975 2019

2019

Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts

Delgado-Calle, J., Kurihara, N., Atkinson, E. G., Nelson, J., Miyagawa, K., Galmarini, C. M., Roodman, G. D. & Bellido, T., Apr 12 2019, In : Oncotarget. 10, 28, p. 2709-2721 13 p.

Research output: Contribution to journalArticle

Osteoclasts
Multiple Myeloma
Dexamethasone
Bone Development
Osteoblasts
2 Citations (Scopus)

The role of cement augmentation with percutaneous vertebroplasty and balloon kyphoplasty for the treatment of vertebral compression fractures in multiple myeloma: a consensus statement from the International Myeloma Working Group (IMWG)

Kyriakou, C., Molloy, S., Vrionis, F., Alberico, R., Bastian, L., Zonder, J. A., Giralt, S., Raje, N., Kyle, R. A., Roodman, G. D., Dimopoulos, M. A., Rajkumar, S. V., Durie, B. B. G. & Terpos, E., Mar 1 2019, In : Blood Cancer Journal. 9, 3, 27.

Research output: Contribution to journalArticle

Open Access
Kyphoplasty
Compression Fractures
Multiple Myeloma
Consensus
Pain
2018
3 Citations (Scopus)

A cost-effectiveness analysis of denosumab for the prevention of skeletal-related events in patients with multiple myeloma in the United States of America

Raje, N., Roodman, G. D., Willenbacher, W., Shimizu, K., García-Sanz, R., Terpos, E., Kennedy, L., Sabatelli, L., Intorcia, M. & Hechmati, G., Mar 6 2018, (Accepted/In press) In : Journal of Medical Economics. p. 1-12 12 p.

Research output: Contribution to journalArticle

zoledronic acid
Multiple Myeloma
Cost-Benefit Analysis
Costs and Cost Analysis
Disease-Free Survival
4 Citations (Scopus)

Bones in Multiple Myeloma: Imaging and Therapy

Zamagni, E., Cavo, M., Fakhri, B., Vij, R. & Roodman, G. D., May 23 2018, In : American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting. 38, p. 638-646 9 p.

Research output: Contribution to journalReview article

Bone Diseases
Multiple Myeloma
Disease Management
Bone and Bones
RANK Ligand

Cancer and bone

Guise, T. & Roodman, G. D., Jan 1 2018, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. wiley, p. 737-738 2 p.

Research output: Chapter in Book/Report/Conference proceedingForeword/postscript

Bone Neoplasms
Bone
56 Citations (Scopus)

Denosumab versus zoledronic acid in bone disease treatment of newly diagnosed multiple myeloma: An international, double-blind, double-dummy, randomised, controlled, phase 3 study

Raje, N., Terpos, E., Willenbacher, W., Shimizu, K., García-Sanz, R., Durie, B., Legieć, W., Krejčí, M., Laribi, K., Zhu, L., Cheng, P., Warner, D. & Roodman, G. D., Jan 1 2018, (Accepted/In press) In : The Lancet Oncology.

Research output: Contribution to journalArticle

zoledronic acid
Bone Diseases
Multiple Myeloma
Therapeutics
Safety
1 Citation (Scopus)

Growth factor independence 1 expression in myeloma cells enhances their growth, survival, and osteoclastogenesis

Petrusca, D., Toscani, D., Wang, F. M., Park, C., Crean, C. D., Anderson, J. L., Marino, S., Mohammad, K., Zhou, D., Silbermann, R., Sun, Q., Kurihara, N., Galson, D. L., Giuliani, N. & Roodman, G. D., Oct 4 2018, In : Journal of Hematology and Oncology. 11, 1, 123.

Research output: Contribution to journalArticle

Multiple Myeloma
Osteogenesis
Intercellular Signaling Peptides and Proteins
Survival
Growth

Mechanisms of osteolytic and osteoblastic skeletal lesions

Roodman, G. D. & Guise, T., Jan 1 2018, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. wiley, p. 739-742 4 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone
Tumors
Cells
Neoplasms
Neoplasm Metastasis
3 Citations (Scopus)

Multiple myeloma and bone: The fatal interaction

Marino, S. & Roodman, G. D., Aug 1 2018, In : Cold Spring Harbor perspectives in medicine. 8, 8, a031286.

Research output: Contribution to journalArticle

Multiple Myeloma
Bone
Bone and Bones
Bone Diseases
Spontaneous Fractures
2 Citations (Scopus)

Osteoblast suppression in multiple myeloma bone disease

Adamik, J., Galson, D. L. & Roodman, G. D., Nov 1 2018, In : Journal of Bone Oncology. 13, p. 62-70 9 p.

Research output: Contribution to journalReview article

Bone Diseases
Osteoblasts
Multiple Myeloma
Mesenchymal Stromal Cells
Bone Marrow
1 Citation (Scopus)

Paget disease of bone

Charles, J. F., Siris, E. S. & Roodman, G. D., Jan 1 2018, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. wiley, p. 713-720 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Osteitis Deformans
Bone
Osteoclasts
Diphosphonates
Medical History Taking

Primer on the metabolic bone diseases and disorders of mineral metabolism

Bilezikian, J. P., Bouillon, R., Clemens, T., Compston, J., Bauer, D. C., Ebeling, P. R., Engelke, K., Goltzman, D., Guise, T., Jan De Beur, S. M., Jüppner, H., Lyons, K., McCauley, L., McClung, M. R., Miller, P. D., Papapoulos, S. E., Roodman, G. D., Rosen, C. J., Seeman, E., Thakker, R. V. & 2 others, Whyte, M. P. & Zaidi, M., Jan 1 2018, wiley. 1105 p.

Research output: Book/ReportBook

Metabolic Bone Diseases
Metabolism
Minerals
Bone
Bone Diseases
27 Citations (Scopus)

Role of bone-modifying agents in multiple myeloma: American society of clinical oncology clinical practice guideline update

Anderson, K., Ismaila, N., Flynn, P. J., Halabi, S., Jagannath, S., Ogaily, M. S., Omel, J., Raje, N., Roodman, G. D., Yee, G. C. & Kyle, R. A., Mar 10 2018, In : Journal of Clinical Oncology. 36, 8, p. 812-818 7 p.

Research output: Contribution to journalArticle

zoledronic acid
pamidronate
Medical Oncology
Multiple Myeloma
Practice Guidelines

Supportive care in multiple myeloma

Doshi, S. M., Noff, T. T. & Roodman, G. D., Jan 1 2018, Neoplastic Diseases of the Blood. Springer International Publishing, p. 595-607 13 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Multiple Myeloma
Leukemia
Thrombosis
Bone Diseases
Kidney
2 Citations (Scopus)

XRK3F2 inhibition of p62-ZZ domain signaling rescues myeloma-induced GFI1-driven epigenetic repression of the Runx2 gene in pre-osteoblasts to overcome differentiation suppression

Adamik, J., Silbermann, R., Marino, S., Sun, Q., Anderson, J. L., Zhou, D., Xie, X. Q., Roodman, G. D. & Galson, D. L., Jun 29 2018, In : Frontiers in Endocrinology. 9, JUL, 344.

Research output: Contribution to journalArticle

Epigenetic Repression
Osteoblasts
Mesenchymal Stromal Cells
Histone Deacetylase 1
Tissue Donors
2017
19 Citations (Scopus)

Bone pain induced by multiple myeloma is reduced by targeting V-ATPase and ASIC3

Hiasa, M., Okui, T., Allette, Y. M., Ripsch, M. S., Sun-Wada, G. H., Wakabayashi, H., Roodman, G. D., White, F. & Yoneda, T., Mar 15 2017, In : Cancer Research. 77, 6, p. 1283-1295 13 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Adenosine Triphosphatases
zoledronic acid
Bone and Bones
Pain
21 Citations (Scopus)

EZH2 or HDAC1 inhibition reverses multiple myeloma-induced epigenetic suppression of osteoblast differentiation

Adamik, J., Jin, S., Sun, Q., Zhang, P., Weiss, K. R., Anderson, J. L., Silbermann, R., Roodman, G. D. & Galson, D. L., Apr 1 2017, In : Molecular Cancer Research. 15, 4, p. 405-417 13 p.

Research output: Contribution to journalArticle

Osteoblasts
Multiple Myeloma
Epigenomics
Chromatin
Histones
22 Citations (Scopus)

Genetic deletion of Sost or pharmacological inhibition of sclerostin prevent multiple myeloma-induced bone disease without affecting tumor growth

Delgado-Calle, J., Anderson, J., Cregor, M. D., Condon, K. W., Kuhstoss, S. A., Plotkin, L., Bellido, T. & Roodman, G. D., Dec 1 2017, In : Leukemia. 31, 12, p. 2686-2694 9 p.

Research output: Contribution to journalArticle

Bone Diseases
Multiple Myeloma
Pharmacology
Growth
Neoplasms
53 Citations (Scopus)

Management of Aromatase Inhibitor-Associated Bone Loss (AIBL) in postmenopausal women with hormone sensitive breast cancer: Joint position statement of the IOF, CABS, ECTS, IEG, ESCEO IMS, and SIOG

Hadji, P., Aapro, M. S., Body, J. J., Gnant, M., Brandi, M. L., Reginster, J. Y., Zillikens, M. C., Glüer, C. C., de Villiers, T., Baber, R., Roodman, G. D., Cooper, C., Langdahl, B., Palacios, S., Kanis, J., Al-Daghri, N., Nogues, X., Eriksen, E. F., Kurth, A., Rizzoli, R. & 1 others, Coleman, R. E., Jun 1 2017, In : Journal of Bone Oncology. 7, p. 1-12 12 p.

Research output: Contribution to journalReview article

Aromatase Inhibitors
Postmenopausal Osteoporosis
Joints
Hormones
Breast Neoplasms
5 Citations (Scopus)

NEK2 induces osteoclast differentiation and bone destruction via heparanase in multiple myeloma

Hao, M., Franqui-Machin, R., Xu, H., Shaughnessy, J., Barlogie, B., Roodman, G. D., Quelle, D. E., Janz, S., Tomasson, M. H., Sanderson, R. D., Qiu, L., Frech, I., Tricot, G. & Zhan, F., Jul 1 2017, In : Leukemia. 31, 7, p. 1648-1650 3 p.

Research output: Contribution to journalLetter

Vitamin D and Paget's Disease

Kurihara, N. & Roodman, G. D., Dec 14 2017, Health, Disease and Therapeutics. Elsevier Inc., Vol. 2. p. 571-579 9 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

osteoclasts
vitamin D
Vitamin D
Osteoclasts
Measles virus
2016
61 Citations (Scopus)
Osteocytes
Tumor Microenvironment
Multiple Myeloma
Bone Marrow
Cell Proliferation
16 Citations (Scopus)

Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo

Teramachi, J., Silbermann, R., Yang, P., Zhao, W., Mohammad, K., Guo, J., Anderson, J. L., Zhou, D., Feng, R., Myint, K. Z., Maertz, N., Beumer, J. H., Eiseman, J. L., Windle, J. J., Xie, X. Q., Roodman, G. D. & Kurihara, N., Feb 1 2016, In : Leukemia. 30, 2, p. 390-398 9 p.

Research output: Contribution to journalArticle

Osteoclasts
Multiple Myeloma
Osteogenesis
Bone and Bones
Growth
10 Citations (Scopus)

Bone disease in multiple myeloma

Eda, H., Santo, L., Roodman, G. D. & Raje, N., Jan 1 2016, Cancer Treatment and Research. Kluwer Academic Publishers, p. 251-270 20 p. (Cancer Treatment and Research; vol. 169).

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone Diseases
Multiple Myeloma
Osteoblasts
Osteoclasts
Bone Remodeling
13 Citations (Scopus)

Current Controversies in the Management of Myeloma Bone Disease

Silbermann, R. & Roodman, G. D., Nov 1 2016, In : Journal of Cellular Physiology. 231, 11, p. 2374-2379 6 p.

Research output: Contribution to journalReview article

Bone Diseases
Bone
Anabolic Agents
Diphosphonates
Proteasome Endopeptidase Complex

Developmental Aspects of Pagetic Osteoclasts

Galson, D. L., Sun, Q. & Roodman, G. D., May 9 2016, Advances in Pathobiology and Management of Paget's Disease of Bone. Elsevier Inc., p. 37-53 17 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Osteoclasts
Osteitis Deformans
Osteogenesis
RANK Ligand
Phenotype
30 Citations (Scopus)

Evaluating results from the multiple myeloma patient subset treated with denosumab or zoledronic acid in a randomized phase 3 trial

Raje, N., Vadhan-Raj, S., Willenbacher, W., Terpos, E., Hungria, V., Spencer, A., Alexeeva, Y., Facon, T., Stewart, A. K., Feng, A., Braun, A., Balakumaran, A. & Roodman, G. D., Jan 8 2016, In : Blood Cancer Journal. 6, e378.

Research output: Contribution to journalArticle

zoledronic acid
Multiple Myeloma
Confidence Intervals
Survival
Lost to Follow-Up
15 Citations (Scopus)

Galectin-1 suppression delineates a new strategy to inhibit myeloma-induced angiogenesis and tumoral growth in vivo

Storti, P., Marchica, V., Airoldi, I., Donofrio, G., Fiorini, E., Ferri, V., Guasco, D., Todoerti, K., Silbermann, R., Anderson, J. L., Zhao, W., Agnelli, L., Bolzoni, M., Martella, E., Mancini, C., Campanini, N., Noonan, D. M., Petronini, P. G., Neri, A., Aversa, F. & 2 others, Roodman, G. D. & Giuliani, N., Jun 17 2016, (Accepted/In press) In : Leukemia.

Research output: Contribution to journalArticle

Galectin 1
Multiple Myeloma
Growth
Small Interfering RNA
Down-Regulation
15 Citations (Scopus)

Measles virus nucleocapsid protein increases osteoblast differentiation in Paget's disease

Teramachi, J., Nagata, Y., Mohammad, K., Inagaki, Y., Ohata, Y., Guise, T., Michou, L., Brown, J. P., Windle, J. J., Kurihara, N. & Roodman, G. D., Mar 1 2016, In : Journal of Clinical Investigation. 126, 3, p. 1012-1022 11 p.

Research output: Contribution to journalArticle

Osteoclasts
Osteoblasts
Bone Resorption
Osteogenesis
Interleukin-6
25 Citations (Scopus)

Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease

Fu, J., Li, S., Feng, R., Ma, H., Sabeh, F., Roodman, G. D., Wang, J., Robinson, S., Guo, X. E., Lund, T., Normolle, D., Mapara, M. Y., Weiss, S. J. & Lentzsch, S., May 2 2016, In : Journal of Clinical Investigation. 126, 5, p. 1759-1772 14 p.

Research output: Contribution to journalArticle

Osteoclasts
Matrix Metalloproteinases
Multiple Myeloma
Bone Diseases
Matrix Metalloproteinase 13
2015
7 Citations (Scopus)

A Phase II trial of weekly bortezomib and dexamethasone in veterans with newly diagnosed multiple myeloma not eligible for or who deferred autologous stem cell transplantation

Girnius, S. K., Lee, S., Kambhampati, S., Rose, M. G., Mohiuddin, A., Houranieh, A., Zimelman, A., Grady, T., Mehta, P., Behler, C., Hayes, T. G., Efebera, Y. A., Prabhala, R. H., Han, A., Yellapragada, S. V., Klein, C. E., Roodman, G. D., Lichtenstein, A. & Munshi, N. C., Apr 1 2015, In : British Journal of Haematology. 169, 1, p. 36-43 8 p.

Research output: Contribution to journalArticle

Stem Cell Transplantation
Veterans
Multiple Myeloma
Dexamethasone
Peripheral Nervous System Diseases
10 Citations (Scopus)
Osteitis Deformans
Osteoclasts
Bone Marrow Cells
Cultured Cells
Interleukin-6
103 Citations (Scopus)

Excess TGF-β mediates muscle weakness associated with bone metastases in mice

Waning, D. L., Mohammad, K., Reiken, S., Xie, W., Andersson, D. C., John, S., Chiechi, A., Wright, L., Umanskaya, A., Niewolna, M., Trivedi, T., Charkhzarrin, S., Khatiwada, P., Wronska, A., Haynes, A., Benassi, M. S., Witzmann, F., Zhen, G., Wang, X., Cao, X. & 3 others, Roodman, G. D., Marks, A. R. & Guise, T., Nov 1 2015, In : Nature Medicine. 21, 11, p. 1262-1271 10 p.

Research output: Contribution to journalArticle

Muscle Weakness
Transforming Growth Factors
Ryanodine Receptor Calcium Release Channel
Muscle
Bone
154 Citations (Scopus)

Role of magnetic resonance imaging in the management of patients with multiple myeloma: A consensus statement

Dimopoulos, M. A., Hillengass, J., Usmani, S., Zamagni, E., Lentzsch, S., Davies, F. E., Raje, N., Sezer, O., Zweegman, S., Shah, J., Badros, A., Shimizu, K., Moreau, P., Chim, C. S., Lahuerta, J. J., Hou, J., Jurczyszyn, A., Goldschmidt, H., Sonneveld, P., Palumbo, A. & 8 others, Ludwig, H., Cavo, M., Barlogie, B., Anderson, K., Roodman, G. D., Rajkumar, S. V., Durie, B. G. M. & Terpos, E., Feb 20 2015, In : Journal of Clinical Oncology. 33, 6, p. 657-664 8 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Magnetic Resonance Imaging
Bone and Bones
Spinal Nerves
Osteoporotic Fractures
4 Citations (Scopus)

Targeting cannabinoid receptor-2 pathway by phenylacetylamide suppresses the proliferation of human myeloma cells through mitotic dysregulation and cytoskeleton disruption

Feng, R., Tong, Q., Xie, Z., Cheng, H., Wang, L., Lentzsch, S., Roodman, G. D. & Xie, X. Q., Dec 1 2015, In : Molecular Carcinogenesis. 54, 12, p. 1796-1806 11 p.

Research output: Contribution to journalArticle

Cannabinoid Receptors
Cytoskeleton
Multiple Myeloma
rimonabant
Transcription Factor CHOP

The Role of the Immune System in the Effects of Cancer on Bone

Silbermann, R. & Roodman, G. D., Oct 6 2015, Osteoimmunology: Interactions of the Immune and Skeletal Systems: Second Edition. Elsevier Inc., p. 311-324 14 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Bone Neoplasms
Immune System
Bone Development
Bone and Bones
Neoplasms
2014
11 Citations (Scopus)

Advances in supportive care for multiple myeloma

Raje, N. S., Yee, A. J. & Roodman, G. D., 2014, In : JNCCN Journal of the National Comprehensive Cancer Network. 12, 4, p. 502-511 10 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Bone Diseases
Diphosphonates
Peripheral Nervous System Diseases
Appointments and Schedules
6 Citations (Scopus)

Autoreactivity to glucose regulated protein 78 links emphysema and osteoporosis in smokers

Bon, J., Kahloon, R., Zhang, Y., Xue, J., Fuhrman, C. R., Tan, J., Burger, M., Kass, D. J., Csizmadia, E., Otterbein, L., Chandra, D., Bhargava, A., Pilewski, J. M., Roodman, G. D., Sciurba, F. C. & Duncan, S. R., 2014, In : PLoS One. 9, 9, p. e105066

Research output: Contribution to journalArticle

osteoporosis
Emphysema
Osteoporosis
glucose
autoantibodies
32 Citations (Scopus)

Bone marrow monocyte-/macrophage-derived activin A mediates the osteoclastogenic effect of IL-3 in multiple myeloma

Silbermann, R., Bolzoni, M., Storti, P., Guasco, D., Bonomini, S., Zhou, D., Wu, J., Anderson, J. L., Windle, J. J., Aversa, F., Roodman, G. D. & Giuliani, N., 2014, In : Leukemia. 28, 4, p. 951-954 4 p.

Research output: Contribution to journalArticle

RANK Ligand
Activins
Interleukin-3
Bone Diseases
Osteoclasts
2 Citations (Scopus)

CCN1: A sticky issue in myeloma

Roodman, G. D., Sep 25 2014, In : Blood. 124, 13, p. 2006-2008 3 p.

Research output: Contribution to journalArticle

Blood
Disease-Free Survival
Bone Marrow
Survival
Therapeutics
12 Citations (Scopus)

Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone

Teramachi, J., Zhou, H., Subler, M. A., Kitagawa, Y., Galson, D. L., Dempster, D. W., Windle, J. J., Kurihara, N. & Roodman, G. D., 2014, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 6, p. 1456-1465 10 p.

Research output: Contribution to journalArticle

Osteitis Deformans
Osteoclasts
Interleukin-6
Bone and Bones
Transgenic Mice
49 Citations (Scopus)

Management of bone disease in multiple myeloma

Terpos, E., Berenson, J., Raje, N. & Roodman, G. D., Feb 2014, In : Expert Review of Hematology. 7, 1, p. 113-125 13 p.

Research output: Contribution to journalArticle

zoledronic acid
Bone Diseases
Multiple Myeloma
pamidronate
Diphosphonates
150 Citations (Scopus)

New drugs and novel mechanisms of action in multiple myeloma in 2013: A report from the International Myeloma Working Group (IMWG)

Ocio, E. M., Richardson, P. G., Rajkumar, S. V., Palumbo, A., Mateos, M. V., Orlowski, R., Kumar, S., Usmani, S., Roodman, G. D., Niesvizky, R., Einsele, H., Anderson, K. C., Dimopoulos, M. A., Avet-Loiseau, H., Mellqvist, U. H., Turesson, I., Merlini, G., Schots, R., Mccarthy, P., Bergsagel, L. & 14 others, Chim, C. S., Lahuerta, J. J., Shah, J., Reiman, A., Mikhael, J., Zweegman, S., Lonial, S., Comenzo, R., Chng, W. J., Moreau, P., Sonneveld, P., Ludwig, H., Durie, B. G. M. & Miguel, J. F. S., 2014, In : Leukemia. 28, 3, p. 525-542 18 p.

Research output: Contribution to journalArticle

Multiple Myeloma
Pharmaceutical Preparations
Dexamethasone
Unfolded Protein Response
Kinesin

Pathophysiology of Bone Metastases

Chirgwin, J. & Roodman, G. D., 2014, Cancer Metastasis - Biology and Treatment. 1 ed. Vol. 21. p. 3-17 15 p. (Cancer Metastasis - Biology and Treatment; vol. 21, no. 1).

Research output: Chapter in Book/Report/Conference proceedingChapter

Neoplasm Metastasis
Bone and Bones
Neoplasms
Skeleton
Growth
19 Citations (Scopus)

Phase I trial of bortezomib (PS-341; NSC 681239) and "nonhybrid" (Bolus) infusion schedule of alvocidib (Flavopiridol; NSC 649890) in patients with recurrent or refractory indolent B-cell neoplasms

Holkova, B., Kmieciak, M., Perkins, E. B., Bose, P., Baz, R. C., Roodman, G. D., Stuart, R. K., Ramakrishnan, V., Wan, W., Peer, C. J., Dawson, J., Kang, L., Honeycutt, C., Tombes, M. B., Shrader, E., Weir-Wiggins, C., Wellons, M., Sankala, H., Hogan, K. T., Colevas, A. D. & 6 others, Doyle, L. A., Figg, W. D., Coppola, D., Roberts, J. D., Sullivan, D. & Grant, S., Nov 15 2014, In : Clinical Cancer Research. 20, 22, p. 5652-5662 11 p.

Research output: Contribution to journalArticle

alvocidib
Appointments and Schedules
B-Lymphocytes
Maximum Tolerated Dose
Neoplasms
30 Citations (Scopus)
Osteocytes
Bone Diseases
Multiple Myeloma
Osteogenesis
Bone and Bones
14 Citations (Scopus)
Osteoclasts
Phosphotransferases
Monocytes
Interleukin-6
Bone Marrow
34 Citations (Scopus)

Whole-body low-dose computed tomography and advanced imaging techniques for multiple myeloma bone disease

Pianko, M. J., Terpos, E., Roodman, G. D., Divgi, C. R., Zweegman, S., Hillengass, J. & Lentzsch, S., Dec 1 2014, In : Clinical Cancer Research. 20, 23, p. 5888-5897 10 p.

Research output: Contribution to journalArticle

Bone Diseases
Multiple Myeloma
Tomography
X-Rays
Radiography
2013
30 Citations (Scopus)

Critical role of AKT protein in myeloma-induced osteoclast formation and osteolysis

Cao, H., Zhu, K., Qiu, L., Li, S., Niu, H., Hao, M., Yang, S., Zhao, Z., Lai, Y., Anderson, J. L., Fan, J., Im, H. J., Chen, D., Roodman, G. D. & Xiao, G., Oct 18 2013, In : Journal of Biological Chemistry. 288, 42, p. 30399-30410 12 p.

Research output: Contribution to journalArticle

Myeloma Proteins
Osteolysis
Osteoclasts
Bone
Proteins
3 Citations (Scopus)

Hematologic Malignancies and Bone

Silbermann, R. & Roodman, G. D., Jul 19 2013, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism: Eighth Edition. Wiley Blackwell, p. 694-701 8 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Hematologic Neoplasms
Bone
Bone and Bones
Bone Diseases
Multiple Myeloma