G. David Roodman

  • 23995 Citations
  • 81 h-Index
1975 …2020

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

2001

Studies in Paget's disease and their relevance to oncology

Roodman, G. D., Jan 1 2001, In : Seminars in oncology. 28, 4 SUPPL. 11, p. 15-21 7 p.

Research output: Contribution to journalArticle

22 Scopus citations
2000

1,25-dihydroxyvitamin D3 hypersensitivity of osteoclast precursors from patients with Paget's disease

Menaa, C., Barsony, J., Reddy, S. V., Cornish, J., Cundy, T. & Roodman, G. D., Jan 1 2000, In : Journal of Bone and Mineral Research. 15, 2, p. 228-236 9 p.

Research output: Contribution to journalArticle

81 Scopus citations

A murine model of inflammatory bone disease

Hentunen, T. A., Choi, S. J., Boyce, B. F., Dallas, M. R., Dallas, S. L., Shen-Ong, G. L. & Roodman, G. D., Feb 1 2000, In : Bone. 26, 2, p. 183-188 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

A phase I-II clinical trial with a combination of gemcitabine (GEMZAR) and paclitaxel (TAXOL) for the treatment of refractory multiple myeloma (MM) patients

Gazitt, Y., Roodman, D., Freytes, C., Shaughnessy, P., Callander, N., Traynor, A. & Rothenberg, M., Dec 1 2000, In : Blood. 96, 11 PART II, p. 287b

Research output: Contribution to journalArticle

3 Scopus citations

Assignment of OSTF1 to human chromosome bands 12q24.1 → q24.2 by in situ hybridization

Schaub, R., Dupont, B., Roodman, G. D., Leach, R. J. & Reddy, S. V., Apr 11 2000, In : Cytogenetics and Cell Genetics. 88, 1-2, p. 87-88 2 p.

Research output: Contribution to journalArticle

3 Scopus citations

CFU-GM-derived cells form osteoclasts at a very high efficiency

Menaa, C., Kurihara, N. & Roodman, G. D., Jan 27 2000, In : Biochemical and Biophysical Research Communications. 267, 3, p. 943-946 4 p.

Research output: Contribution to journalArticle

49 Scopus citations

Clinical presentation of hispanic (H) patients (PTS) with multiple myeloma (MM) in bexar county (BC), Texas

Callander, N. S., Galvez, J., Cortes, R., Aisina, M. & Roodman, G. D., Dec 1 2000, In : Blood. 96, 11 PART II, p. 271b

Research output: Contribution to journalArticle

Effect of telomere and telomerase interactive agents on human tumor and normal cell lines

Rha, S. Y., Izbicka, E., Lawrence, R., Davidson, K., Sun, D., Moyer, M. P., Roodman, G. D., Hurley, L. & Von Hoff, D., Mar 1 2000, In : Clinical Cancer Research. 6, 3, p. 987-993 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

Enhanced RANK ligand expression and responsivity of bone marrow cells in Paget's disease of bone

Menaa, C., Reddy, S. V., Kurihara, N., Maeda, H., Anderson, D., Cundy, T., Cornish, J., Singer, F. R., Bruder, J. M. & Roodman, G. D., Jan 1 2000, In : Journal of Clinical Investigation. 105, 12, p. 1833-1838 6 p.

Research output: Contribution to journalArticle

Open Access
132 Scopus citations

Expansile skeletal hyperphosphatasia: A new familial metabolic bone disease

Whyte, M. P., Mills, B. G., Reinus, W. R., Podgornik, M. N., Roodman, G. D., Gannon, F. H., Eddy, M. C. & Mcalister, W. H., Jan 1 2000, In : Journal of Bone and Mineral Research. 15, 12, p. 2330-2344 15 p.

Research output: Contribution to journalArticle

57 Scopus citations

Macrophage inflammatory protein 1-alpha is a potential osteoclast stimulatory factor in multiple myeloma

Choi, S. J., Cruz, J. C., Craig, F., Chung, H., Devlin, R. D., Roodman, G. D. & Alsina, M., Jul 15 2000, In : Blood. 96, 2, p. 671-675 5 p.

Research output: Contribution to journalArticle

329 Scopus citations

Osteoclasts expressing the measles virus nucleocapsid gene display a pagetic phenotype

Kurihara, N., Reddy, S. V., Menaa, C., Anderson, D. & Roodman, G. D., Mar 2000, In : Journal of Clinical Investigation. 105, 5, p. 607-614 8 p.

Research output: Contribution to journalArticle

Open Access
106 Scopus citations

Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption

The American Society For Bone And Mineral Research President'S Committee On Nomenclature, Jan 1 2000, In : Bone. 27, 6, p. 761-764 4 p.

Research output: Contribution to journalArticle

17 Scopus citations
1999

Annexin II increases osteoclast formation by stimulating the proliferation of osteoclast precursors in human marrow cultures

Menaa, C., Devlin, R. D., Reddy, S. V., Gazitt, Y., Choi, S. J. & Roodman, G. D., Jun 1999, In : Journal of Clinical Investigation. 103, 11, p. 1605-1613 9 p.

Research output: Contribution to journalArticle

Open Access
82 Scopus citations

Cell biology of Paget's disease

Reddy, S. V., Menaa, C., Singer, F. R., Demulder, A. & Roodman, G. D., Oct 7 1999, In : Journal of Bone and Mineral Research. 14, SUPPL. 2, p. 3-8 6 p.

Research output: Contribution to journalArticle

48 Scopus citations

Cell biology of the osteoclast

Roodman, G. D., Aug 1 1999, In : Experimental Hematology. 27, 8, p. 1229-1241 13 p.

Research output: Contribution to journalReview article

412 Scopus citations

Characterization of immortalized osteoclast precursors developed from mice transgenic for both bcl-X(L) and simian virus 40 large T antigen

Hentunen, T. A., Jackson, S. H., Chung, H., Reddy, S. V., Lorenzo, J., Choi, S. J. & David Roodman, G., Jan 1 1999, In : Endocrinology. 140, 7, p. 2954-2961 8 p.

Research output: Contribution to journalArticle

Open Access
22 Scopus citations

Effects of alendronate on cytokine production and osteoclast formation induced by human marrow stromal cells

Moore, J., Anderson, J. A., Roodman, G. D. & Reddy, S. V., Feb 1999, In : Journal of Investigative Medicine. 47, 2, p. 132A

Research output: Contribution to journalArticle

Identification of human asparaginyl endopeptidase (legumain) as an inhibitor of osteoclast formation and bone resorption

Choi, S. J., Reddy, S. V., Devlin, R. D., Menaa, C., Chung, H., Boyce, B. F. & Roodman, G. D., Sep 24 1999, In : Journal of Biological Chemistry. 274, 39, p. 27747-27753 7 p.

Research output: Contribution to journalArticle

77 Scopus citations

Intracellular fragmentation of bone resorption products by reactive oxygen species generated by osteoclastic tartrate-resistant acid phosphatase

Halleen, J. M., Räisänen, S., Salo, J. J., Reddy, S. V., Roodman, G. D., Hentunen, T. A., Lehenkari, P. P., Kaija, H., Vihko, P. & Väänänen, H. K., Aug 13 1999, In : Journal of Biological Chemistry. 274, 33, p. 22907-22910 4 p.

Research output: Contribution to journalArticle

186 Scopus citations

Measles virus nucleocapsid transcript expression is not restricted to the osteoclast lineage in patients with Paget's disease of bone

Reddy, S. V., Menaa, C., Singer, F. R., Cundy, T., Cornish, J., Whyte, M. P. & Roodman, G. D., Oct 1 1999, In : Experimental Hematology. 27, 10, p. 1528-1532 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Mechanisms of abnormal bone turnover in Paget's disease

Roodman, G. D., May 1999, In : Bone. 24, 5 SUPPL., p. 39S-40S

Research output: Contribution to journalArticle

10 Scopus citations

Osteoclast function in healthy subjects and in patients with Paget's disease

Wirfel, K. L., Bruder, J. M., Vardag, A. & Roodman, G. D., Jan 1 1999, In : Endocrinologist. 9, 4, p. 263-269 7 p.

Research output: Contribution to journalReview article

1 Scopus citations

Variable disease severity associated with a Paget's disease predisposition gene

Leach, R. J., Singer, F. R., Cody, J. D. & Roodman, G. D., Jan 1 1999, In : Journal of Bone and Mineral Research. 14, SUPPL. 2, p. 17-20 4 p.

Research output: Contribution to journalArticle

18 Scopus citations
1998

Animal models of bone disease

David Roodman, G., Dec 1 1998, In : Cancer Research Therapy and Control. 6, 1-4, p. 89-90 2 p.

Research output: Contribution to journalArticle

Antibodies to Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in patients with multiple myeloma

Gao, S. J., Alsina, M., Deng, J. H., Harrison, C. R., Montalvo, E. A., Leach, C. T., David Roodman, G. & Jenson, H. B., Jan 1 1998, In : Journal of Infectious Diseases. 178, 3, p. 846-849 4 p.

Research output: Contribution to journalArticle

50 Scopus citations

Cadherin-6 mediates the heterotypic interactions between the hemopoietic osteoclast cell lineage and stromal cells in a murine model of osteoclast differentiation

Mbalaviele, G., Nishimura, R., Myoi, A., Niewolna, M., Reddy, S. V., Chen, D., Feng, J., Roodman, D., Mundy, G. R. & Yoneda, T., Jun 15 1998, In : Journal of Cell Biology. 141, 6, p. 1467-1476 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Cloning and identification of human Sca as a novel inhibitor of osteoclast formation and bone resorption

Choi, S. J., Devlin, R. D., Menaa, C., Chung, H., Roodman, G. D. & Reddy, S. V., Oct 1 1998, In : Journal of Clinical Investigation. 102, 7, p. 1360-1368 9 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Cloning and identification of human stem cell antigen as a novel inhibitor of osteoclast formation and bone resorption

Choi, S. J., Davlin, R., Baddy, S. V. & Roodman, G. D., Dec 1 1998, In : Experimental Hematology. 26, 8, 1 p.

Research output: Contribution to journalArticle

Control of osteoclast differentiation

Reddy, S. V. & Roodman, G. D., Jan 1 1998, In : Critical Reviews in Eukaryotic Gene Expression. 8, 1, p. 1-17 17 p.

Research output: Contribution to journalReview article

60 Scopus citations

Epitope mapping of recombinant human procathepsin D

Sachdev, D., Ohsaki, Y., Roodman, G. D. & Chirgwin, J. M., Dec 1 1998, In : Advances in experimental medicine and biology. 436, p. 185-189 5 p.

Research output: Contribution to journalArticle

Evidence for a novel osteosarcoma tumor-suppressor gene in the chromosome 18 region genetically linked with Paget disease of bone

Nellissery, M. J., Padalecki, S. S., Brkanac, Z., Singer, F. R., Roodman, G. D., Unni, K. K., Leach, R. J. & Hansen, M. F., Sep 1998, In : American Journal of Human Genetics. 63, 3, p. 817-824 8 p.

Research output: Contribution to journalArticle

80 Scopus citations

Further characterization of the murine collagenase (type IVB) gene promoter and analysis of mRNA expression in murine tissues

Roach, J., Jin Choi, S., L. Schaub, R., Leach, R. J., David Roodman, G. & Reddy, S. V., Feb 22 1998, In : Gene. 208, 2, p. 117-122 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

IL-6 mediates the effects of IL-1 or TNF, but not PTHrP or 1,25(OH)2D3, on osteoclast-like cell formation in normal human bone marrow cultures

Devlin, R. D., Reddy, S. V., Savino, R., Ciliberto, G. & Roodman, G. D., Apr 14 1998, In : Journal of Bone and Mineral Research. 13, 3, p. 393-399 7 p.

Research output: Contribution to journalArticle

78 Scopus citations

Immortalization of osteoclast precursors by targeting bcl-X(L) and Simian Virus 40 large T antigen to the osteoclast lineage in transgenic mice

Hentunen, T. A., Reddy, S. V., Boyce, B. F., Devlin, R., Park, H. R., Chung, H., Selander, K. S., Dallas, M., Kurihara, N., Galson, D. L., Goldring, S. R., Koop, B. A., Windle, J. J. & Roodman, G. D., Jul 1 1998, In : Journal of Clinical Investigation. 102, 1, p. 88-97 10 p.

Research output: Contribution to journalArticle

Open Access
44 Scopus citations

Isolation and characterization of a cDNA clone encoding a novel peptide (OSF) that enhances osteoclast formation and bone resorption

Reddy, S., Devlin, R., Menaa, C., Nishimura, R., Choi, S. J., Dallas, M., Yoneda, T. & Roodman, G. D., Dec 1998, In : Journal of cellular physiology. 177, 4, p. 636-645 10 p.

Research output: Contribution to journalArticle

41 Scopus citations

Osteoclast differentiation and activity

Roodman, G. D., Jan 1 1998, In : Biochemical Society transactions. 26, 1, p. 7-13 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

Pagetic osteoclasts formed in vitro: Absence of paracrystalline inclusions

Roodman, G. D., Ohsaki, Y., Miller, M. M., Demulder, A., Hosking, D., Singer, F. R. & McManus, L. M., Apr 1 1998, In : Journal of Submicroscopic Cytology and Pathology. 30, 2, p. 315-327 13 p.

Research output: Contribution to journalArticle

2 Scopus citations

Paget's Disease of Bone

Roodman, G. D., Dec 1 1998, In : Advances in Organ Biology. 5, C, p. 661-675 15 p.

Research output: Contribution to journalArticle

1 Scopus citations
1997

Cokeromyces recurvatus infection in a bone marrow transplant recipient

Tsai, T. W., Hammond, L. A., Rinaldi, M., Martin, K., Tio, F., Maples, J., Freytes, C. O. & Roodman, G. D., Feb 1 1997, In : Bone Marrow Transplantation. 19, 3, p. 301-302 2 p.

Research output: Contribution to journalArticle

Open Access
12 Scopus citations

Genetic linkage of Paget disease of the bone to chromosome 18q

Cody, J. D., Singer, F. R., Roodman, G. D., Otterund, B., Lewis, T. B., Leppert, M. & Leach, R. J., Nov 1997, In : American Journal of Human Genetics. 61, 5, p. 1117-1122 6 p.

Research output: Contribution to journalArticle

131 Scopus citations

Mechanisms of bone lesions in multiple myeloma and lymphoma

Roodman, G. D., Oct 15 1997, In : Cancer. 80, 8 SUPPL., p. 1557-1563 7 p.

Research output: Contribution to journalArticle

146 Scopus citations

Tumor necrosis factor enhances parathyroid hormone-related protein- induced hypercalcemia and bone resorption without inhibiting: Bone formation in vivo

Uy, H. L., Mundy, G. R., Boyce, B. F., Story, B. M., Dunstan, C. R., Yin, J. J., Roodman, G. D. & Guise, T. A., Sep 2 1997, In : Cancer Research. 57, 15, p. 3194-3199 6 p.

Research output: Contribution to journalArticle

46 Scopus citations
1996

Absence of paramyxo virus transcripts in juvenile Paget bone disease.

Whyte, M. P., Leelawattana, R., Reddy, S. V. & Roodman, G. D., Jul 1 1996, In : Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 11, 7, 1 p.

Research output: Contribution to journalComment/debate

8 Scopus citations

Advances in bone biology: The osteoclast

Roodman, G. D., Sep 3 1996, In : Endocrine Reviews. 17, 4, p. 308-332 25 p.

Research output: Contribution to journalReview article

445 Scopus citations

A new model for the regulation of bone resorption, with particular reference to the effects of bisphosphonates

Parfitt, A. M., Mundy, G. R., Roodman, G. D., Hughes, D. E. & Boyce, B. F., Feb 1 1996, In : Journal of Bone and Mineral Research. 11, 2, p. 150-159 10 p.

Research output: Contribution to journalReview article

267 Scopus citations

Assignment of matrix metalloproteinase 9 (Mmp9) to mouse Chromosome 2 bands H1-H2

DuPont, B. R., Linn, R., Knight, C. B., Roodman, G. D., Sakaguchi, A. Y., Lalley, P. A., Fournier, R. E. K. & Leach, R. J., Jan 1 1996, In : Cytogenetic and Genome Research. 74, 1-2, p. 118-119 2 p.

Research output: Contribution to journalArticle

2 Scopus citations

Cytokine Regulation of Bone Cell Differentiation

Alsina, M., Guise, T. A. & Roodman, G. D., 1996, Vitamins and Hormones. C ed. Academic Press Inc., p. 63-98 36 p. (Vitamins and Hormones; vol. 52, no. C).

Research output: Chapter in Book/Report/Conference proceedingChapter

29 Scopus citations

Detection of measles virus nucleocapsid transcripts in circulating blood cells from patients with paget disease

Reddy, S. V., Singer, F. R., Mallette, L. & Roodman, G. D., Nov 1996, In : Journal of Bone and Mineral Research. 11, 11, p. 1602-1607 6 p.

Research output: Contribution to journalArticle

79 Scopus citations

Development of an in vivo model of human multiple myeloma bone disease

Alsina, M., Boyce, B., Devlin, R. D., Anderson, J. L., Craig, F., Mundy, G. R. & Roodman, G. D., Feb 15 1996, In : Blood. 87, 4, p. 1495-1501 7 p.

Research output: Contribution to journalArticle

81 Scopus citations