G. David Roodman

  • 23995 Citations
  • 81 h-Index
1975 …2020

Research output per year

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Publications

1990

Induction of differentiation of the human promyelocytic HL-60 cells into cells with the osteoclastic phenotype

Yoneda, T., Mundy, G. R. & Roodman, G. D., Jan 1 1990, Calcium regulation and bone metabolism. Basic and clinical aspects: proceedings of the 10th International Conference on calcium regulating hormones and bone metabolism. ICS886. Cohn, D. V., Glorieux, F. H., Martin, T. J., Cohn, D. V., Glorieux, F. H. & Martin, T. J. (eds.). Elsevier Science Publishers B.V., p. 425-429 5 p. (Calcium regulation and bone metabolism. Basic and clinical aspects: proceedings of the 10th International Conference on calcium regulating hormones and bone metabolism. ICS886).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

40 Scopus citations

Mixed lymphocyte culture reactivity of fetal baboons: Application for in utero bone marrow transplantation

Muirhead, D. Y., Kuehl, T. J., Vandeberg, J. L., Menchaca, E. M., Downs, M. P. & Roodman, G. D., Jan 1 1990, In : Bone Marrow Transplantation. 6, 4, p. 263-267 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Osteoinductive factor inhibits formation of human osteoclast-like cells

Kukita, A., Bonewald, L., Rosen, D., Seyedin, S., Mundy, G. R. & Roodman, G. D., Jan 1 1990, In : Proceedings of the National Academy of Sciences of the United States of America. 87, 8, p. 3023-3026 4 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations
38 Scopus citations
46 Scopus citations

Tumor necrosis factor α and the anemia of chronic disease: Effects of chronic exposure to TNF on erythropoiesis in vivo

Roodman, G. D., Johnson, R. A. & Clibon, U., Oct 2 1990, Advances in Experimental Medicine and Biology. Vol. 271. p. 185-196 12 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

20 Scopus citations
1989

Chronic exposure to tumor necrosis factor in vivo preferentially inhibits erythropoiesis in nude mice

Johnson, R. A., Waddelow, T. A., Caro, J., Oliff, A. & Roodman, G. D., Jan 1 1989, In : Blood. 74, 1, p. 130-138 9 p.

Research output: Contribution to journalArticle

141 Scopus citations
17 Scopus citations

Hematologic manifestations of malignancy

Johnson, R. A. & Roodman, G. D., Nov 1989, In : Disease-a-Month. 35, 11, p. 726-768 43 p.

Research output: Contribution to journalArticle

35 Scopus citations

Hemin-induced erythroid differentiation changes the sensitivity of K562 cells to tumor necrosis factor-α

Li, X. F., Anderson, J., Hutzler, D. & Roodman, G. D., Dec 1 1989, In : Experimental Hematology. 17, 11, p. 1059-1062 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Interleukin‐1 and tumor necrosis factor stimulate the formation of human osteoclastlike cells in vitro

Pfeilschifter, J., Chenu, C., Bird, A., Mundy, G. R. & Roodman, D. G., Feb 1989, In : Journal of Bone and Mineral Research. 4, 1, p. 113-118 6 p.

Research output: Contribution to journalArticle

371 Scopus citations

Osteoclast-like cells formed in long-term human bone marrow cultures express a similar surface phenotype as authentic osteoclasts

Kukita, T., McManus, L. M., Miller, M., Civin, C. & Roodman, G. D., Jan 1 1989, In : Laboratory Investigation. 60, 4, p. 532-538 7 p.

Research output: Contribution to journalArticle

41 Scopus citations

Osteoclast-like cells form in long-term human bone marrow but not in peripheral blood cultures

Takahashi, N., Kukita, T., MacDonald, B. R., Bird, A., Mundy, G. R., McManus, L. M., Miller, M., Boyde, A., Jones, S. J. & Roodman, G. D., Jan 1 1989, In : Journal of Clinical Investigation. 83, 2, p. 543-550 8 p.

Research output: Contribution to journalArticle

Open Access
61 Scopus citations

Tumor necrosis factor alpha is a cytotoxin induced by murine Chlamydia trachomatis infection

Williams, D. M., Bonewald, L. F., Roodman, G. D., Byrne, G. I., Magee, D. M. & Schachter, J., Jan 1 1989, In : Infection and immunity. 57, 5, p. 1351-1355 5 p.

Research output: Contribution to journalArticle

35 Scopus citations

Tumors producing human tumor necrosis factor induce hypercalcemia and osteoclastic bone resorption in nude mice

Johnson, R. A., Boyce, B. F., Mundy, G. R. & Roodman, G. D., Mar 1989, In : Endocrinology. 124, 3, p. 1424-1427 4 p.

Research output: Contribution to journalArticle

125 Scopus citations
1988

In utero bone marrow transplantation of fetal baboons with mismatched adult marrow: Initial observations

Roodman, G. D., Vandeberg, J. L. & Kuehl, T. J., Jan 1 1988, In : Bone Marrow Transplantation. 3, 2, p. 141-147 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

Model systems of osteoclast differentiation

Roodman, G. D., Dec 1 1988, In : Journal of Bone and Mineral Metabolism. 6, 3, p. 1-11 11 p.

Research output: Contribution to journalReview article

1 Scopus citations

Osteoclast-like cell formation and its regulation by osteotropic hormones in mouse bone marrow cultures

Takahashi, N., Yamana, H., Yoshiki, S., Suda, T., Roodman, G. D., Mundy, G. R. & Boyde, A., Apr 1 1988, In : Endocrinology. 122, 4, p. 1373-1382 10 p.

Research output: Contribution to journalArticle

668 Scopus citations

Transforming growth factor β inhibits formation of osteoclast-like cells in long-term human marrow cultures

Chenu, C., Pfeilschifter, J., Mundy, G. R. & Roodman, G. D., Jan 1 1988, In : Proceedings of the National Academy of Sciences of the United States of America. 85, 15, p. 5683-5687 5 p.

Research output: Contribution to journalArticle

Open Access
244 Scopus citations
1987

CFU-GEMM correlate with neutrophil and platelet recovery in patients receiving autologous marrow transplantation after high-dose melphalan chemotherapy.

Roodman, G. D., LeMaistre, C. F., Clark, G. M., Page, C. P., Newcomb, T. F. & Knight, W. A., Aug 1987, In : Bone marrow transplantation. 2, 2, p. 165-173 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Developmental changes in membrane proteins from baboon erythrocytes

Lee, J. C., Kuehl, T. J. & Roodman, G. D., 1987, In : Comparative Biochemistry and Physiology -- Part B: Biochemistry and. 88, 1, p. 233-236 4 p.

Research output: Contribution to journalArticle

Formation of multinucleated cells that respond to osteotropic hormones in long term human bone marrow cultures

Macdonald, B. R., Takahashi, N., McManus, L. M., Holahan, J., Mundy, G. R. & Roodman, G. D., Jun 1987, In : Endocrinology. 120, 6, p. 2326-2333 8 p.

Research output: Contribution to journalArticle

143 Scopus citations

Hematology-oncology. Hematology-Oncology Workgroup, Legislative Task Force on Cancer in Texas.

Gardner, F. H., Alperin, J. B., Belli, J. A., Farley, P. C., Frenkel, E. P., Redman, J. R., Roodman, G. D., Sears, D. A. & Trowbridge, A. A., Sep 1 1987, In : Texas Medicine. 83, 9 Pt 2, p. 59-71 13 p.

Research output: Contribution to journalArticle

Mechanisms of erythroid suppression in the anemia of chronic disease

Roodman, G. D., Jan 1 1987, In : Blood Cells. 13, 1-2, p. 171-184 14 p.

Research output: Contribution to journalArticle

32 Scopus citations
21 Scopus citations
128 Scopus citations
1986

Effects of human recombinant CSF‐GM and highly purified CSF‐1 on the formation of multinucleated cells with osteoclast characteristics in long‐term bone marrow cultures

MacDonald, B. R., Mundy, G. R., Clark, S., Wang, E. A., Kuehl, T. J., Stanley, E. R. & Roodman, G. D., Apr 1986, In : Journal of Bone and Mineral Research. 1, 2, p. 227-233 7 p.

Research output: Contribution to journalArticle

169 Scopus citations

Recombinant human interferon-γ inhibits formation of human osteoclast-like cells

Takahashi, N., Mundy, G. R. & Roodman, G. D., Dec 1 1986, In : Journal of Immunology. 137, 11, p. 3544-3549 6 p.

Research output: Contribution to journalArticle

158 Scopus citations

Recombinant human transforming growth factor-alpha stimulates the formation of osteoclast-like cells in long-term human marrow cultures

Takahashi, N., MacDonald, B. R., Hon, J., Winkler, M. E., Derynck, R., Mundy, G. R. & Roodman, G. D., Jan 1 1986, In : Journal of Clinical Investigation. 78, 4, p. 894-898 5 p.

Research output: Contribution to journalArticle

Open Access
91 Scopus citations
1985

1,25-dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow

Roodman, G. D., Ibbotson, K. J., MacDonald, B. R., Kuehl, T. J. & Mundy, G. R., Dec 1 1985, In : Proceedings of the National Academy of Sciences of the United States of America. 82, 23, p. 8213-8217 5 p.

Research output: Contribution to journalArticle

232 Scopus citations

Expression of latent hematopoietic progenitor cells in cultures of newborn and adult baboon liver

Roodman, G. D., VandeBerg, J. L. & Kuehl, T. J., Jan 1 1985, In : Blood. 65, 6, p. 1518-1525 8 p.

Research output: Contribution to journalArticle

3 Scopus citations
1984

Identification and characterization of osteoclast-like cells and their progenitors in cultures of feline marrow mononuclear cells

Ibbotson, K. J., Roodman, G. D., McManus, L. M. & Mundy, G. R., Jan 1 1984, In : Journal of Cell Biology. 99, 2, p. 471-480 10 p.

Research output: Contribution to journalArticle

Open Access
177 Scopus citations
1983

Effects of dexamethasone on erythroid colony and burst formation from human fetal liver and adult marrow

Roodman, G. D., Lee, J. & Gidari, A. S., Apr 1983, In : British journal of haematology. 53, 4, p. 621-628 8 p.

Research output: Contribution to journalArticle

13 Scopus citations

Inhibition of erythroid colony formation by autologous bone marrow adherent cells from patients with the anemia of chronic disease

Roodman, G. D., Horadam, V. W. & Wright, T. L., Jan 1 1983, In : Blood. 62, 2, p. 406-412 7 p.

Research output: Contribution to journalArticle

27 Scopus citations
1982
7 Scopus citations
1981

Effects of Shortened Erythropoietin Exposure on Sheep Marrow Cultures

Roodman, G. D., Kaplan, J. M., Kaplan, M. E. & Zanjani, E. D., Feb 1981, In : British journal of haematology. 47, 2, p. 195-201 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

Stimulation of erythroid colony formation in vitro by erythropoietin immobilized on agarose-bound lectins

Roodman, G. D., Spivak, J. L. & Zanjani, E. D., Nov 1981, In : The Journal of Laboratory and Clinical Medicine. 98, 5, p. 684-690 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
1980

Aplastic Anemia Associated With Rubber Cement Used by a Marathon Runner

Roodman, G. D., Reese, E. P. & Cardamone, J. M., May 1980, In : Archives of Internal Medicine. 140, 5, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

Autoimmune pancytopenia: Lymphocyte inhibition of autologous but not allogenic bone marrow growth in vitro

David Roodman, G., Ascensao, J. L., Banisadre, M., Bloom, P. M. & Zanjani, E. D., Jan 1 1980, In : American Journal of Medicine. 69, 2, p. 325-328 4 p.

Research output: Contribution to journalArticle

7 Scopus citations
1979

Endogenous erythroid colony-forming cells in fetal and newborn sheep

Roodman, G. D. & Zanjani, E. D., Dec 1 1979, In : Journal of Laboratory and Clinical Medicine. 94, 5, p. 699-707 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
1976
19 Scopus citations
1975

DNA polymerase activities during erythropoiesis. Effects of erythropoietin, vinblastine, colcemid, and daunomycin

Roodman, G. D., Hutton, J. J. & Bollum, F. J., Mar 15 1975, In : Experimental Cell Research. 91, 2, p. 269-278 10 p.

Research output: Contribution to journalArticle

22 Scopus citations