Research Output per year
Publications
Article
(23S)-25-dehydro-1α-hydroxyvitamin D3-26,23-lactone, a vitamin D receptor antagonist that inhibits osteoclast formation and bone resorption in bone marrow cultures front patients with Paget's disease
Ishizuka, S., Kurihara, N., Reddy, S. V., Cornish, J., Gundy, T. & Roodman, G. D., Apr 1 2005, In : Endocrinology. 146, 4, p. 2023-2030 8 p.Research output: Contribution to journal › Article
48
Scopus
citations
1,25-dihydroxyvitamin D3 causes formation of multinucleated cells with several osteoclast characteristics in cultures of primate marrow
Roodman, G. D., Ibbotson, K. J., MacDonald, B. R., Kuehl, T. J. & Mundy, G. R., 1985, In : Proceedings of the National Academy of Sciences of the United States of America. 82, 23, p. 8213-8217 5 p.Research output: Contribution to journal › Article
233
Scopus
citations
1,25-dihydroxyvitamin D3 hypersensitivity of osteoclast precursors from patients with Paget's disease
Menaa, C., Barsony, J., Reddy, S. V., Cornish, J., Cundy, T. & Roodman, G. D., 2000, In : Journal of Bone and Mineral Research. 15, 2, p. 228-236 9 p.Research output: Contribution to journal › Article
81
Scopus
citations
1α,25-Dihydroxyvitamin D3-26,23-lactam analogues function as vitamin D receptor antagonists in human and rodent cells
Ishizuka, S., Kurihara, N., Hiruma, Y., Miura, D., Namekawa, J. I., Tamura, A., Kato-Nakamura, Y., Nakano, Y., Takenouchi, K., Hashimoto, Y., Nagasawa, K. & Roodman, G. D., Jun 1 2008, In : Journal of Steroid Biochemistry and Molecular Biology. 110, 3-5, p. 269-277 9 p.Research output: Contribution to journal › Article
13
Scopus
citations
5-Lipoxygenase metabolites of arachidonic acid stimulate isolated osteoclasts to resorb calcified matrices
Gallwitz, W. E., Mundy, G. R., Lee, C. H., Qiao, M., Roodman, G. D., Raftery, M., Gaskell, S. J. & Bonewald, L. F., 1993, In : Journal of Biological Chemistry. 268, 14, p. 10087-10094 8 p.Research output: Contribution to journal › Article
77
Scopus
citations
Abnormalities in osteoclast precursors and marrow accessory cells in paget’s disease
Demulder, A., Takahashi, S., Singer, F. R., Hosking, D. J. & Roodman, G. D., Nov 1993, In : Endocrinology. 133, 5, p. 1978-1982 5 p.Research output: Contribution to journal › Article
65
Scopus
citations
A cost-effectiveness analysis of denosumab for the prevention of skeletal-related events in patients with multiple myeloma in the United States of America
Raje, N., Roodman, G. D., Willenbacher, W., Shimizu, K., García-Sanz, R., Terpos, E., Kennedy, L., Sabatelli, L., Intorcia, M. & Hechmati, G., May 4 2018, In : Journal of Medical Economics. 21, 5, p. 525-536 12 p.Research output: Contribution to journal › Article
7
Scopus
citations
Activating transcription factor 4 regulates osteoclast differentiation in mice
Cao, H., Yu, S., Yao, Z., Galson, D. L., Jiang, Y., Zhang, X., Fan, J., Lu, B., Guan, Y., Luo, M., Lai, Y., Zhu, Y., Kurihara, N., Patrene, K., Roodman, G. D. & Xiao, G., Aug 2 2010, In : Journal of Clinical Investigation. 120, 8, p. 2755-2766 12 p.Research output: Contribution to journal › Article
49
Scopus
citations
ADAM8: A novel osteoclast stimulating factor
Choi, S. J., Han, J. H. & Roodman, G. D., Jan 1 2001, In : Journal of Bone and Mineral Research. 16, 5, p. 814-822 9 p.Research output: Contribution to journal › Article
87
Scopus
citations
ADAM8 enhances osteoclast precursor fusion and osteoclast formation in vitro and in vivo
Ishizuka, H., García-Palacios, V., Lu, G., Subler, M. A., Zhang, H., Boykin, C. S., Choi, S. J., Zhao, L., Patrene, K., Galson, D. L., Blair, H. C., Hadi, T. M., Windle, J. J., Kurihara, N. & Roodman, G. D., Jan 2011, In : Journal of Bone and Mineral Research. 26, 1, p. 169-181 13 p.Research output: Contribution to journal › Article
25
Scopus
citations
Advances in supportive care for multiple myeloma
Raje, N. S., Yee, A. J. & Roodman, G. D., Jan 1 2014, In : JNCCN Journal of the National Comprehensive Cancer Network. 12, 4, p. 502-511 10 p.Research output: Contribution to journal › Article
12
Scopus
citations
Advances in treating metastatic bone cancer: Summary statement for the First Cambridge Conference
Lipton, A., Berenson, J. R., Body, J. J., Boyce, B. F., Bruland, O. S., Carducci, M. A., Cleeland, C. S., Clohisy, D. R., Coleman, R. E., Cook, R. J., Guise, T. A., Pearse, R. N., Powles, T. J., Rogers, M. J., Roodman, G. D., Smith, M. R., Suva, L. J., Vessella, R. L., Weilbaecher, K. N. & King, L., Oct 15 2006, In : Clinical Cancer Research. 12, 20 PART 2, p. 6209s-6212sResearch output: Contribution to journal › Article
11
Scopus
citations
AML-1A and AML-1B regulation of MIP-1α expression in multiple myeloma
Choi, S. J., Oba, T., Callander, N. S., Jelinek, D. F. & Roodman, G. D., May 15 2003, In : Blood. 101, 10, p. 3778-3783 6 p.Research output: Contribution to journal › Article
36
Scopus
citations
A murine model of inflammatory bone disease
Hentunen, T. A., Choi, S. J., Boyce, B. F., Dallas, M. R., Dallas, S. L., Shen-Ong, G. L. & Roodman, G. D., Feb 1 2000, In : Bone. 26, 2, p. 183-188 6 p.Research output: Contribution to journal › Article
27
Scopus
citations
Animal models of bone disease
David Roodman, G., Dec 1 1998, In : Cancer Research Therapy and Control. 6, 1-4, p. 89-90 2 p.Research output: Contribution to journal › Article
An in vivo model of human multiple myeloma bone disease
Alsina, M., Boyce, B. F., Mundy, G. R. & Roodman, G. D., Jan 1 1995, In : STEM CELLS. 13, SUPPL. 2, p. 48-50 3 p.Research output: Contribution to journal › Article
8
Scopus
citations
Annexin-2 is a regulator of stromal cell-derived factor-1/CXCL12 function in the hematopoietic stem cell endosteal niche
Jung, Y., Shiozawa, Y., Wang, J., Patel, L. R., Havens, A. M., Song, J., Krebsbach, P. H., Roodman, G. D. & Taichman, R. S., Feb 2011, In : Experimental Hematology. 39, 2, p. 151-166.e1Research output: Contribution to journal › Article
34
Scopus
citations
Annexin II/annexin II receptor axis regulates adhesion, migration, homing, and growth of prostate cancer
Shiozawa, Y., Havens, A. M., Jung, Y., Ziegler, A. M., Pedersen, E. A., Wang, J., Wang, J., Lu, G., Roodman, G. D., Loberg, R. D., Pienta, K. J. & Taichman, R. S., Oct 1 2008, In : Journal of Cellular Biochemistry. 105, 2, p. 370-380 11 p.Research output: Contribution to journal › Article
163
Scopus
citations
Annexin II increases osteoclast formation by stimulating the proliferation of osteoclast precursors in human marrow cultures
Menaa, C., Devlin, R. D., Reddy, S. V., Gazitt, Y., Choi, S. J. & Roodman, G. D., Jun 1999, In : Journal of Clinical Investigation. 103, 11, p. 1605-1613 9 p.Research output: Contribution to journal › Article
Open Access
83
Scopus
citations
Annexin II interactions with the annexin II receptor enhance multiple myeloma cell adhesion and growth in the bone marrow microenvironment
D'Souza, S., Kurihara, N., Shiozawa, Y., Joseph, J., Taichman, R., Galson, D. L. & Roodman, G. D., Feb 23 2012, In : Blood. 119, 8, p. 1888-1896 9 p.Research output: Contribution to journal › Article
44
Scopus
citations
Annexin II stimulates RANKL expression through MAPK
Li, F., Chung, H. Y., Reddy, S. V., Lu, G., Kurihara, N., Zhao, A. Z. & Roodman, G. D., Jul 2005, In : Journal of Bone and Mineral Research. 20, 7, p. 1161-1167 7 p.Research output: Contribution to journal › Article
46
Scopus
citations
A novel role of IL-17-producing lymphocytes in mediating lytic bone disease in multiple myeloma
Noonan, K., Marchionni, L., Anderson, J., Pardoll, D., Roodman, G. D. & Borrello, I., Nov 4 2010, In : Blood. 116, 18, p. 3554-3563 10 p.Research output: Contribution to journal › Article
122
Scopus
citations
Antibodies to Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in patients with multiple myeloma
Gao, S. J., Alsina, M., Deng, J. H., Harrison, C. R., Montalvo, E. A., Leach, C. T., David Roodman, G. & Jenson, H. B., Jan 1 1998, In : Journal of Infectious Diseases. 178, 3, p. 846-849 4 p.Research output: Contribution to journal › Article
50
Scopus
citations
Antisense inhibition of macrophage inflammatory protein 1-α blocks bone destruction in a model of myeloma bone disease
Choi, S. J., Oba, Y., Gazitt, Y., Alsina, M., Cruz, J., Anderson, J. & David Roodman, G., 2001, In : Journal of Clinical Investigation. 108, 12, p. 1833-1841 9 p.Research output: Contribution to journal › Article
184
Scopus
citations
A phase I clinical and pharmacological profile of dacarbazine with autologous bone marrow transplantation in patients with solid tumors
Adkins, D. R., Irvin, R., Kuhn, J., Boldt, D. H., Roodman, G. D., Salzman, D., Freytes, C., Von Hoff, D. D. & LeMaistre, C. F., Jun 1993, In : Investigational New Drugs. 11, 2-3, p. 169-179 11 p.Research output: Contribution to journal › Article
8
Scopus
citations
A phase I-II clinical trial with a combination of gemcitabine (GEMZAR) and paclitaxel (TAXOL) for the treatment of refractory multiple myeloma (MM) patients
Gazitt, Y., Roodman, D., Freytes, C., Shaughnessy, P., Callander, N., Traynor, A. & Rothenberg, M., Dec 1 2000, In : Blood. 96, 11 PART II, p. 287bResearch output: Contribution to journal › Article
3
Scopus
citations
A Phase II trial of weekly bortezomib and dexamethasone in veterans with newly diagnosed multiple myeloma not eligible for or who deferred autologous stem cell transplantation
Girnius, S. K., Lee, S., Kambhampati, S., Rose, M. G., Mohiuddin, A., Houranieh, A., Zimelman, A., Grady, T., Mehta, P., Behler, C., Hayes, T. G., Efebera, Y. A., Prabhala, R. H., Han, A., Yellapragada, S. V., Klein, C. E., Roodman, G. D., Lichtenstein, A. & Munshi, N. C., Apr 1 2015, In : British journal of haematology. 169, 1, p. 36-43 8 p.Research output: Contribution to journal › Article
8
Scopus
citations
Aplastic Anemia Associated With Rubber Cement Used by a Marathon Runner
Roodman, G. D., Reese, E. P. & Cardamone, J. M., May 1980, In : Archives of Internal Medicine. 140, 5, 1 p.Research output: Contribution to journal › Article
1
Scopus
citations
Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts
Delgado-Calle, J., Kurihara, N., Atkinson, E. G., Nelson, J., Miyagawa, K., Galmarini, C. M., Roodman, G. D. & Bellido, T., Apr 12 2019, In : Oncotarget. 10, 28, p. 2709-2721 13 p.Research output: Contribution to journal › Article
2
Scopus
citations
Application of Bone Marrow Cultures to the Study of Osteoclast Formation and Osteoclast Precursors in Man
Roodman, G. D., Mar 14 2015, In : Calcified Tissue International. 56, 1, p. S22-S23Research output: Contribution to journal › Article
10
Scopus
citations
ASCO 2007 clinical practice guideline update on the role of bisphosphonates in multiple myeloma: Guideline summary
Kyle, R. A., Yee, G. C., Somerfield, M. R., Flynn, P. J., Halabi, S., Jagannath, S., Orlowski, R. Z., Roodman, D. G., Twilde, P. & Anderson, K., Jul 1 2007, In : Journal of Oncology Practice. 3, 4, 1 p.Research output: Contribution to journal › Article
1
Scopus
citations
A SQSTM1/p62 mutation linked to Paget's disease increases the osteoclastogenic potential of the bone microenvironment
Hiruma, Y., Kurihara, N., Subler, M. A., Zhou, H., Boykin, C. S., Zhang, H., Ishizuka, S., Dempster, D. W., Roodman, G. D. & Windle, J. J., Nov 19 2008, In : Human molecular genetics. 17, 23, p. 3708-3719 12 p.Research output: Contribution to journal › Article
65
Scopus
citations
Assays for Bone Resorption and Bone Formation
Mundy, G. R., Roodman, G. D., Bonewald, L. F., Oreffo, R. O. C. & Boyce, B. F., Jan 1 1991, In : Methods in Enzymology. 198, C, p. 502-510 9 p.Research output: Contribution to journal › Article
10
Scopus
citations
Assignment of matrix metalloproteinase 9 (Mmp9) to mouse Chromosome 2 bands H1-H2
DuPont, B. R., Linn, R., Knight, C. B., Roodman, G. D., Sakaguchi, A. Y., Lalley, P. A., Fournier, R. E. K. & Leach, R. J., Jan 1 1996, In : Cytogenetic and Genome Research. 74, 1-2, p. 118-119 2 p.Research output: Contribution to journal › Article
2
Scopus
citations
Assignment of OSTF1 to human chromosome bands 12q24.1 → q24.2 by in situ hybridization
Schaub, R., Dupont, B., Roodman, G. D., Leach, R. J. & Reddy, S. V., 2000, In : Cytogenetics and Cell Genetics. 88, 1-2, p. 87-88 2 p.Research output: Contribution to journal › Article
3
Scopus
citations
Assignment of the mouse tartrate-resistant acid phosphatase gene (acp5) to chromosome 9
Grimes, R., Reddy, S. V., Leach, R. J., Scarcez, T., Roodman, G. D., Sakaguchi, A. Y., Lalley, P. A. & Windle, J. J., Feb 1993, In : Genomics. 15, 2, p. 421-422 2 p.Research output: Contribution to journal › Article
14
Scopus
citations
Atypical multinucleated cells form in long-term marrow cultures from patients with Paget's disease
Kukita, A., Chenu, C., McManus, L. M., Mundy, G. R. & Roodman, G. D., 1990, In : Journal of Clinical Investigation. 85, 4, p. 1280-1286 7 p.Research output: Contribution to journal › Article
Open Access
69
Scopus
citations
Autoimmune pancytopenia: Lymphocyte inhibition of autologous but not allogenic bone marrow growth in vitro
David Roodman, G., Ascensao, J. L., Banisadre, M., Bloom, P. M. & Zanjani, E. D., 1980, In : American Journal of Medicine. 69, 2, p. 325-328 4 p.Research output: Contribution to journal › Article
7
Scopus
citations
Autophagy promotes T-cell survival through degradation of proteins of the cell death machinery
Kovacs, J. R., Li, C., Yang, Q., Li, G., Garcia, I. G., Ju, S., Roodman, D. G., Windle, J. J., Zhang, X. & Lu, B., Jan 2012, In : Cell Death and Differentiation. 19, 1, p. 144-152 9 p.Research output: Contribution to journal › Article
117
Scopus
citations
Autoreactivity to glucose regulated protein 78 links emphysema and osteoporosis in smokers
Bon, J., Kahloon, R., Zhang, Y., Xue, J., Fuhrman, C. R., Tan, J., Burger, M., Kass, D. J., Csizmadia, E., Otterbein, L., Chandra, D., Bhargava, A., Pilewski, J. M., Roodman, G. D., Sciurba, F. C. & Duncan, S. R., Sep 2014, In : PloS one. 9, 9, e105066.Research output: Contribution to journal › Article
8
Scopus
citations
Bidirectional notch signaling and osteocyte-derived factors in the bone marrow microenvironment promote tumor cell proliferation and bone destruction in multiple myeloma
Delgado-Calle, J., Anderson, J., Cregor, M. D., Hiasa, M., Chirgwin, J. M., Carlesso, N., Yoneda, T., Mohammad, K. S., Plotkin, L. I., Roodman, G. D. & Bellido, T., Mar 1 2016, In : Cancer Research. 76, 5, p. 1089-1100 12 p.Research output: Contribution to journal › Article
80
Scopus
citations
Biology of osteoclast activation in cancer
Roodman, G. D., Aug 1 2001, In : Journal of Clinical Oncology. 19, 15, p. 3562-3571 10 p.Research output: Contribution to journal › Article
241
Scopus
citations
Biology of the osteoclast in Paget's disease
Roodman, G. D., Feb 1994, In : Seminars in Arthritis and Rheumatism. 23, 4, p. 235-236 2 p.Research output: Contribution to journal › Article
4
Scopus
citations
Bisphosphonates promote apoptosis in murine osteoclasts in vitro and in vivo
Hughes, D. E., Wright, K. R., Uy, H. L., Sasaki, A., Yoneda, T., Roodman, D. G., Mundy, G. R. & Boyce, B. F., Oct 1995, In : Journal of Bone and Mineral Research. 10, 10, p. 1478-1487 10 p.Research output: Contribution to journal › Article
873
Scopus
citations
Blocking the ZZ domain of sequestosome1/p62 suppresses myeloma growth and osteoclast formation in vitro and induces dramatic bone formation in myeloma-bearing bones in vivo
Teramachi, J., Silbermann, R., Yang, P., Zhao, W., Mohammad, K. S., Guo, J., Anderson, J. L., Zhou, D., Feng, R., Myint, K. Z., Maertz, N., Beumer, J. H., Eiseman, J. L., Windle, J. J., Xie, X. Q., Roodman, G. D. & Kurihara, N., Feb 1 2016, In : Leukemia. 30, 2, p. 390-398 9 p.Research output: Contribution to journal › Article
22
Scopus
citations
Bone marrow mononuclear cells from patients with Paget’s disease contain measles virus nucleocapsid messenger ribonucleic acid that has mutations in a specific region of the sequence
Reddy, S. V., Singer, F. R. & Roodman, G. D., Jul 1995, In : Journal of Clinical Endocrinology and Metabolism. 80, 7, p. 2108-2111 4 p.Research output: Contribution to journal › Article
101
Scopus
citations
Bone pain induced by multiple myeloma is reduced by targeting V-ATPase and ASIC3
Hiasa, M., Okui, T., Allette, Y. M., Ripsch, M. S., Sun-Wada, G. H., Wakabayashi, H., Roodman, G. D., White, F. A. & Yoneda, T., Mar 15 2017, In : Cancer Research. 77, 6, p. 1283-1295 13 p.Research output: Contribution to journal › Article
25
Scopus
citations
C/EBPβ regulates transcription factors critical for proliferation and survival of multiple myeloma cells
Pal, R., Janz, M., Galson, D. L., Gries, M., Li, S., Jöhrens, K., Anagnostopoulos, I., Dörken, B., Mapara, M. Y., Borghesi, L., Kardava, L., David Roodman, G., Milcarek, C. & Lentzsch, S., Oct 29 2009, In : Blood. 114, 18, p. 3890-3898 9 p.Research output: Contribution to journal › Article
51
Scopus
citations
Cadherin-6 mediates the heterotypic interactions between the hemopoietic osteoclast cell lineage and stromal cells in a murine model of osteoclast differentiation
Mbalaviele, G., Nishimura, R., Myoi, A., Niewolna, M., Reddy, S. V., Chen, D., Feng, J., Roodman, D., Mundy, G. R. & Yoneda, T., Jun 15 1998, In : Journal of Cell Biology. 141, 6, p. 1467-1476 10 p.Research output: Contribution to journal › Article
45
Scopus
citations
Cell biology of Paget's disease
Reddy, S. V., Menaa, C., Singer, F. R., Demulder, A. & Roodman, G. D., 1999, In : Journal of Bone and Mineral Research. 14, SUPPL. 2, p. 3-8 6 p.Research output: Contribution to journal › Article
50
Scopus
citations