Hal Broxmeyer

  • 41168 Citations
  • 99 h-Index
1973 …2020

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37 Scopus citations

4-1BB regulates NKG2D costimulation in human cord blood CD8+ T cells

Kim, Y. J., Han, M. K. & Broxmeyer, H. E., Feb 12 2008, In : Blood. 111, 3, p. 1378-1386 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

5-aminoimidazole-4-carboxyamide ribonucleoside induces G 1/S arrest and nanog downregulation via p53 and enhances erythroid differentiation

Chae, H. D., Lee, M. R. & Broxmeyer, H. E., Feb 1 2012, In : STEM CELLS. 30, 2, p. 140-149 10 p.

Research output: Contribution to journalArticle

34 Scopus citations

Aberrant regulation of hematopoiesis by T cells in BAZF-deficient mice

Broxmeyer, H. E., Sehra, S., Cooper, S., Toney, L. M., Kusam, S., Aloor, J. J., Marchal, C. C., Dinauer, M. C. & Dent, A. L., Aug 1 2007, In : Molecular and cellular biology. 27, 15, p. 5275-5285 11 p.

Research output: Contribution to journalArticle

19 Scopus citations

Abnormal chemokine-induced responses of immature and mature hematopoietic cells from motheaten mice implicate the protein tyrosine phosphatase SHP-1 in chemokine responses

Kim, C. H., Qu, C. K., Hangoc, G., Cooper, S., Anzai, N., Feng, G. S. & Broxmeyer, H. E., Sep 6 1999, In : Journal of Experimental Medicine. 190, 5, p. 681-690 10 p.

Research output: Contribution to journalArticle

79 Scopus citations
41 Scopus citations
Open Access
13 Scopus citations

Abnormal responsiveness of granulocyte-macrophage committed colony-forming cells from patients with chronic myeloid leukemia to inhibition by prostaglandin e

Pelus, L. M., Broxmeyer, H. E., Moore, M. A. S. & Clarkson, B. D., Jul 1 1980, In : Cancer Research. 40, 7, p. 2512-2515 4 p.

Research output: Contribution to journalArticle

40 Scopus citations

Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: Protection at the progenitor cell level

Vadhan-Raj, S., Broxmeyer, H. E., Hittelman, W. N., Papadopoulos, N. E., Chawla, S. P., Fenoglio, C., Cooper, S., Stephen Buescher, E., Frenck, R. W., Hollan, A., Perkins, R. C., Scheule, R. K., Gutterman, J. U., Salem, P. & Benjamin, R. S., Jan 1 1992, In : Journal of Clinical Oncology. 10, 8, p. 1266-1277 12 p.

Research output: Contribution to journalArticle

99 Scopus citations

Acicid isoferritin stimulates differentiation of normal granulomonocytic progenitors

Guimaraes, J. E. T. E., Berney, J. J., Broxmeyer, H. E., Hoffbrand, A. V. & Francis, G. E., Jan 1 1988, In : Leukemia. 2, 7, p. 466-471 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Acidic isoferritin inhibitory activity: A normal granulopoietic regulator within long term mouse bone marrow cultures

Oblon, D. J., Broxmeyer, H. E. & Vellis, K. H., 1983, In : Leukemia Research. 7, 5, p. 581-590 10 p.

Research output: Contribution to journalArticle

4 Scopus citations
Open Access
5 Scopus citations

Acidic isoferritins as feedback regulators in normal and leukemic myelopoiesis.

Broxmeyer, H. E., Bognacki, J., Dörner, M. H., deSousa, M. & Lu, L., Dec 1 1981, In : Hamatologie und Bluttransfusion. 26, p. 243-245 3 p.

Research output: Contribution to journalArticle

Acidic isoferritins do not suppress differentiation of mouse myeloid leukemic M1 cells

Okabe-Kado, J., Hayashi, M., Honma, Y., Hozumi, M. & Broxmeyer, H. E., 1983, In : Leukemia Research. 7, 6, p. 811-815 5 p.

Research output: Contribution to journalArticle

2 Scopus citations

A coiled-coil tetramerization domain of BCR-ABL is essential for the interactions of SH2-containing signal transduction molecules

Tauchi, T., Miyazawa, K., Feng, G. S., Broxmeyer, H. E. & Toyama, K., Jan 25 1997, In : Journal of Biological Chemistry. 272, 2, p. 1389-1394 6 p.

Research output: Contribution to journalArticle

26 Scopus citations

Activation of OCT4 enhances ex vivo expansion of human cord blood hematopoietic stem and progenitor cells by regulating HOXB4 expression

Huang, X., Lee, M. R., Cooper, S., Hangoc, G., Hong, K. S., Chung, H. M. & Broxmeyer, H. E., Jan 1 2016, In : Leukemia. 30, 1, p. 144-153 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
31 Scopus citations

Activities derived from established human myeloid cell lines reverse the suppression of cell line colony formation by lactoferrin and transferrin

Broxmeyer, H. E., Rubin, B. Y., Berman, E., Juliano, L., Lu, L., Hast, L. J., Cooper, S. & Singer, J. W., Apr 9 1986, In : Experimental Hematology. 14, 1, p. 51-59 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Acute myeloid leukemia as the first hematologic manifestation of fanconi anemia

Auerbach, A. D., Weiner, M. A., Warburton, D., Yeboa, K., Lu, L. & Broxmeyer, H. E., May 1982, In : American Journal of Hematology. 12, 3, p. 289-300 12 p.

Research output: Contribution to journalArticle

36 Scopus citations

Adeno-associated virus 2-mediated gene transfer and functional expression of the human granulocyte-macrophage colony-stimulating factor

Luo, F., Zhou, S. Z., Cooper, S., Munshi, N. C., Scott Boswell, H., Broxmeyer, H. E. & Srivastava, A., Jan 1 1995, In : Experimental Hematology. 23, 12, p. 1261-1267 7 p.

Research output: Contribution to journalArticle

11 Scopus citations

Adeno-associated virus 2-mediated gene transfer in murine hematopoietic progenitor cells

Zhen Zhou, S., Broxmeyer, H. E., Cooper, S., Harrington, M. A. & Srivastava, A., Dec 1 1993, In : Experimental Hematology. 21, 7, p. 928-933 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Adeno-associated virus 2-mediated high efficiency gene transfer into irm, nature and mature subsets of hematopoietic progenitor cells in human umbilical cord blood

Zhou, S. Z., Cooper, S., Kang, L. Y., Ruggieri, L., Heimfeld, S., Srivastava, A. & Broxmeyer, H. E., Jun 1 1994, In : Journal of Experimental Medicine. 179, 6, p. 1867-1875 9 p.

Research output: Contribution to journalArticle

98 Scopus citations

Adipose stem cell treatment in mice attenuates lung and systemic injury induced by cigarette smoking

Schweitzer, K. S., Johnstone, B. H., Garrison, J., Rush, N. I., Cooper, S., Traktuev, D. O., Feng, D., Adamowicz, J. J., Van Demark, M., Fisher, A. J., Kamocki, K., Brown, M. B., Presson, R. G., Broxmeyer, H. E., March, K. L. & Petrache, I., Jan 15 2011, In : American journal of respiratory and critical care medicine. 183, 2, p. 215-225 11 p.

Research output: Contribution to journalArticle

118 Scopus citations

A human factor-dependent cell line simulates cobblestone formation under human bone marrow stromal cells in vitro

Mantel, C. R., Balduini, A. & Broxmeyer, H. E., Jan 1 1999, In : Annals of the New York Academy of Sciences. 872, p. 399-401 3 p.

Research output: Contribution to journalArticle

1 Scopus citations
Open Access
40 Scopus citations

Alloantigen priming induces a state of unresponsiveness in human umbilical cord blood T cells

Risdon, G., Gaddy, J., Horie, M. & Broxmeyer, H. E., Mar 14 1995, In : Proceedings of the National Academy of Sciences of the United States of America. 92, 6, p. 2413-2417 5 p.

Research output: Contribution to journalArticle

104 Scopus citations

Allogeneic responses of human umbilical cord blood

Risdon, G., Gaddy, J. & Broxmeyer, H. E., Dec 1 1994, In : Blood Cells. 20, 2-3, p. 566-572 7 p.

Research output: Contribution to journalArticle

53 Scopus citations

Altered hematopoiesis, behavior, and sexual function in μ opioid receptor-deficient mice

Tian, M., Broxmeyer, H. E., Fan, Y., Lai, Z., Zhang, S., Aronica, S., Cooper, S., Bigsby, R. M., Steinmetz, R., Engle, S. J., Mestek, A., Pollock, J. D., Lehman, M. N., Jansen, H. T., Ying, M., Stambrook, P. J., Tischfield, J. A. & Yu, L., Apr 21 1997, In : Journal of Experimental Medicine. 185, 8, p. 1517-1522 6 p.

Research output: Contribution to journalArticle

149 Scopus citations

Altered responsiveness to chemokines due to targeted disruption of SHIP

Kim, C. H., Hangoc, G., Cooper, S., Helgason, C. D., Yew, S., Humphries, R. K., Krystal, G. & Broxmeyer, H. E., Dec 1999, In : Journal of Clinical Investigation. 104, 12, p. 1751-1759 9 p.

Research output: Contribution to journalArticle

Open Access
91 Scopus citations

AMD3100 ameliorates cigarette smoke-induced emphysema-like manifestations in mice

Barwinska, D., Oueini, H., Poirier, C., Albrecht, M. E., Bogatcheva, N. V., Justice, M. J., Saliba, J., Schweitzer, K. S., Broxmeyer, H. E., March, K. L. & Petrache, I., Sep 2018, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 315, 3, p. L382-L386

Research output: Contribution to journalArticle

3 Scopus citations

AMD3100 synergizes with G-CSF to mobilize repopulating stem cells in Fanconi anemia knockout mice

Pulliam, A. C., Hobson, M. J., Ciccone, S. L., Li, Y., Chen, S., Srour, E. F., Yang, F. C., Broxmeyer, H. E. & Clapp, D. W., Sep 1 2008, In : Experimental Hematology. 36, 9, p. 1084-1090 7 p.

Research output: Contribution to journalArticle

27 Scopus citations

Ames hypopituitary dwarf mice demonstrate imbalanced myelopoiesis between bone marrow and spleen

Capitano, M. L., Chitteti, B. R., Cooper, S., Srour, E. F., Bartke, A. & Broxmeyer, H. E., Jun 1 2015, In : Blood Cells, Molecules, and Diseases. 55, 1, p. 15-20 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Amphotropic retrovirus transduction of hematopoietic stem cells

Orlic, D., Girard, L. J., Anderson, S. M., Barrette, S., Broxmeyer, H. E. & Bodine, D. M., Jan 1 1999, In : Annals of the New York Academy of Sciences. 872, p. 115-124 10 p.

Research output: Contribution to journalArticle

12 Scopus citations

Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation

Thomson, B. G., Robertson, K. A., Gowan, D., Heilman, D., Broxmeyer, H. E., Emanuel, D., Kotylo, P., Brahmi, Z. & Smith, F. O., Oct 15 2000, In : Blood. 96, 8, p. 2703-2711 9 p.

Research output: Contribution to journalArticle

206 Scopus citations

A naturally occurring splice variant of CXCL12/stromal cell-derived factor 1 is a potent human immunodeficiency virus type 1 inhibitor with weak chemotaxis and cell survival activities

Altenburg, J. D., Broxmeyer, H. E., Jin, Q., Cooper, S., Basu, S. & Alkhatib, G., Aug 1 2007, In : Journal of virology. 81, 15, p. 8140-8148 9 p.

Research output: Contribution to journalArticle

48 Scopus citations

An expanded role for dipeptidyl peptidase 4 in cell regulation

Ropa, J. & Broxmeyer, H. E., Jul 1 2020, In : Current opinion in hematology. 27, 4, p. 215-224 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Angiopoietin-like-2 and -3 act through their coiled-coil domains to enhance survival and replating capacity of human cord blood hematopoietic progenitors

Broxmeyer, H. E., Srour, E. F., Cooper, S., Wallace, C. T., Hangoc, G. & Youn, B. S., Jan 15 2012, In : Blood Cells, Molecules, and Diseases. 48, 1, p. 25-29 5 p.

Research output: Contribution to journalArticle

18 Scopus citations

A noncytotoxic DsRed variant for whole-cell labeling

Strack, R. L., Strongin, D. E., Bhattacharyya, D., Tao, W., Berman, A., Broxmeyer, H. E., Keenan, R. J. & Glick, B. S., Oct 27 2008, In : Nature Methods. 5, 11, p. 955-957 3 p.

Research output: Contribution to journalArticle

118 Scopus citations

A novel chemokine, macrophage inflammatory protein-related protein-2, inhibits colony formation of bone marrow myeloid progenitors

Youn, B. S., Jang, I. K., Broxmeyer, H. E., Cooper, S., Jenkins, N. A., Gilbert, D. J., Copeland, N. G., Elick, T. A., Fraser, M. J. & Kwon, B. S., Sep 14 1995, In : Journal of Immunology. 155, 5, p. 2661-2667 7 p.

Research output: Contribution to journalArticle

56 Scopus citations

Antagonism of PPAR-γ 3 signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis

Guo, B., Huang, X., Lee, M. R., Lee, S. A. & Broxmeyer, H. E., Mar 1 2018, In : Nature Medicine. 24, 3, p. 360-367 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

Antigenically distinct subpopulations of myeloid progenitor cells (CFU-GM) in human peripheral blood and marrow.

Ferrero, D., Broxmeyer, H. E., Pagliardi, G. L., Venuta, S., Lange, B., Pessano, S. & Rovera, G., Jul 1983, In : Proceedings of the National Academy of Sciences of the United States of America. 80, 13, p. 4114-4118 5 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations

Antitumor activity and immunotherapeutic properties of Flt3-ligand in a murine breast cancer model

Chen, K., Braun, S., Lyman, S., Fan, Y., Traycoff, C. M., Wiebke, E. A., Gaddy, J., Sledge, G., Broxmeyer, H. E. & Cornetta, K., Aug 15 1997, In : Cancer Research. 57, 16, p. 3511-3516 6 p.

Research output: Contribution to journalArticle

108 Scopus citations

Antitumor effect of interleukin 7 in combination with local hyperthermia in mice bearing B16a melanoma cells

Wu, B., Shen, RN. N., Wang, WX. X., Broxmeyer, H. E. & Lu, L., 1993, In : STEM CELLS. 11, 5, p. 412-421 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Anti‐tumor effects of recombinant human macrophage colony‐stimulating factor, alone or in combination with local irradiation, in mice inoculated with lewis lung carcinoma cells

Lu, L., Shen, RN. N., Lin, ZH. H., Aukerman, S. L., Ralph, P. & Broxmeyer, H. E., Jan 2 1991, In : International Journal of Cancer. 47, 1, p. 143-147 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

A pathogenetic role for TNFα in the syndrome of cachexia, arthritis, and autoimmunity resulting from tristetraprolin (TTP) deficiency

Taylor, G. A., Carballo, E., Lee, D. M., Lai, W. S., Thompson, M. J., Patel, D. D., Schenkman, D. I., Gilkeson, G. S., Broxmeyer, H. E., Haynes, B. F. & Blackshear, P. J., May 1996, In : Immunity. 4, 5, p. 445-454 10 p.

Research output: Contribution to journalArticle

569 Scopus citations

A phase i trial of subcutaneous (SC) BB-10010 in breast. Cancer patients (PTS) receiving high-dose cyclophosphamide (C)

Gordon, M. S., McCaskill-Stevens, W. J. & Broxmeyer, H. E., Dec 1 1996, In : Experimental Hematology. 24, 9, 1 p.

Research output: Contribution to journalArticle

1 Scopus citations

A positive effect of p21(cip1/waf1) in the colony formation from murine myeloid progenitor cells as assessed by retroviral-mediated gene transfer

Braun, S. E., Mantel, C., Rosenthal, M., Cooper, S., Liu, L., Robertson, K. A., Hromas, R. & Broxmeyer, H. E., Jun 1998, In : Blood Cells, Molecules and Diseases. 24, 2, p. 138-148 11 p.

Research output: Contribution to journalArticle

34 Scopus citations

A role for class-II major histocompatibility complex antigens in the regulation of myelopoiesis

Broxmeyer, H. E. & Dupont, B., Jan 1 1985, In : Progress in Allergy. VOL. 36, p. 203-221 19 p.

Research output: Contribution to journalArticle

13 Scopus citations

A role for natural killer T cells and CD1d molecules in counteracting suppression of hematopoiesis in mice induced by infection with murine cytomegalovirus

Broxmeyer, H. E., Dent, A., Cooper, S., Hangoc, G., Wang, Z. Y., Du, W., Gervay-Haque, J., Sriram, V., Renukaradhya, G. J. & Brutkiewicz, R. R., Apr 1 2007, In : Experimental Hematology. 35, 4 SUPPL., p. 87-93 7 p.

Research output: Contribution to journalArticle

19 Scopus citations