Hal Broxmeyer

  • 41168 Citations
  • 99 h-Index
1973 …2020

Research output per year

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Publications

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2003
176 Scopus citations

Importance of predosing of recombinant human thrombopoietin to reduce chemotherapy-induced early thrombocytopenia

Vadhan-Raj, S., Patel, S., Bueso-Ramos, C., Folloder, J., Papadopolous, N., Burgess, A., Broemeling, L. D., Broxmeyer, H. E. & Benjamin, R. S., Aug 15 2003, In : Journal of Clinical Oncology. 21, 16, p. 3158-3167 10 p.

Research output: Contribution to journalArticle

42 Scopus citations

Mobilization of hematopoietic progenitor cells in healthy volunteers by AMD3100, a CXCR4 antagonist

Liles, W. C., Broxmeyer, H. E., Rodger, E., Wood, B., Hübel, K., Cooper, S., Hangoc, G., Bridger, G. J., Henson, G. W., Calandra, G. & Dale, D. C., Oct 15 2003, In : Blood. 102, 8, p. 2728-2730 3 p.

Research output: Contribution to journalArticle

573 Scopus citations

NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

Helbig, G., Christopherson, K. W., Bhat-Nakshatri, P., Kumar, S., Kishimoto, H., Miller, K. D., Broxmeyer, H. E. & Nakshatri, H., Jun 13 2003, In : Journal of Biological Chemistry. 278, 24, p. 21631-21638 8 p.

Research output: Contribution to journalArticle

501 Scopus citations

Osteoprotegerin inhibits proliferation of myeloid progenitor cells

Ra, J. S., Broxmeyer, H. E., Kim, M. W., Han, I. S., Choi, S. W. & Kwon, B. S., Feb 1 2003, In : Journal of Hematotherapy and Stem Cell Research. 12, 1, p. 33-38 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Profiling of differentially expressed apoptosis-related genes by cDNA arrays in human cord blood CD34+ cells treated with etoposide

Tao, W., Hangoc, G., Hawes, J. W., Si, Y., Cooper, S. & Broxmeyer, H. E., Mar 1 2003, In : Experimental Hematology. 31, 3, p. 251-260 10 p.

Research output: Contribution to journalArticle

22 Scopus citations

P-selectin enhances generation of CD14+ CD16+ dendritic-like cells and inhibits macrophage maturation from human peripheral blood monocytes

Li, G., Kim, Y. J., Mantel, C. & Broxmeyer, H. E., Jul 15 2003, In : Journal of Immunology. 171, 2, p. 669-677 9 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Retroviral-mediated expression of recombinant Fancc enhances the repopulating ability of Fancc-/- hematopoietic stem cells and decreases the risk of clonal evolution

Haneline, L. S., Li, X., Ciccone, S. L. M., Hong, P., Yang, Y., Broxmeyer, H. E., Lee, S. H., Orazi, A., Srour, E. F. & Clapp, D. W., Feb 15 2003, In : Blood. 101, 4, p. 1299-1307 9 p.

Research output: Contribution to journalArticle

64 Scopus citations

Selective enhancement of multipotential hematopoietic progenitors in vitro and in vivo by IL-20

Liu, L., Ding, C., Zeng, W., Heuer, J. G., Tetreault, J. W., Noblitt, T. W., Hangoc, G., Cooper, S., Brune, K. A., Sharma, G., Fox, N., Rowlinson, S. W., Rogers, D. P., Witcher, D. R., Lambooy, P. K., Wroblewski, V. J., Miller, J. R. & Broxmeyer, H. E., Nov 1 2003, In : Blood. 102, 9, p. 3206-3209 4 p.

Research output: Contribution to journalArticle

42 Scopus citations

Stromal cell-derived factor-1/CXCL12 directly enhances survival/antiapoptosis of myeloid progenitor cells through CXCR4 and Gαi proteins and enhances engraftment of competitive, repopulating stem cells

Broxmeyer, H. E., Kohli, L., Kim, C. H., Lee, Y., Mantel, C., Cooper, S., Hangoc, G., Shaheen, M., Li, X. & Clapp, D. W., May 1 2003, In : Journal of Leukocyte Biology. 73, 5, p. 630-638 9 p.

Research output: Contribution to journalArticle

153 Scopus citations

Synergistic activation of p70S6 kinase associated with stem cell factor in MO7e cells

Lee, Y., Broxmeyer, H. E., Mantel, C., Kwon, H. J., Kim, J. W., Kim, J. S., Kwon, D. & Choe, I. S., Jun 30 2003, In : Experimental and Molecular Medicine. 35, 3, p. 222-226 5 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
Open Access
144 Scopus citations
2002
37 Scopus citations
31 Scopus citations

Cell surface peptidase CD26/dipeptidylpeptidase IV regulates CXCL12/stromal cell-derived factor-1α-mediated chemotaxis of human cord blood CD34+ progenitor cells

Christopherson, K. W., Hangoc, G. & Broxmeyer, H. E., Dec 15 2002, In : Journal of Immunology. 169, 12, p. 7000-7008 9 p.

Research output: Contribution to journalArticle

219 Scopus citations

Chemokine/chemokine receptor nomenclature

Bacon, K., Baggiolini, M., Broxmeyer, H., Horuk, R., Lindley, I., Mantovani, A., Matsushima, K., Murphy, P., Nomiyama, H., Oppenheim, J., Rot, A., Schall, T., Tsang, M., Thorpe, R., Damme, J. V., Wadhwa, M., Yoshie, O., Zlotnik, A. & Zoon, K., Jan 1 2002, In : Journal of Interferon and Cytokine Research. 22, 10, p. 1067-1068 2 p.

Research output: Contribution to journalArticle

237 Scopus citations

c-kit associated with the transmembrane 4 superfamily proteins constitutes a functionally distinct subunit in human hematopoietic progenitors

Anzai, N., Lee, Y., Youn, B. S., Fukuda, S., Kim, Y. J., Mantel, C., Akashi, M. & Broxmeyer, H. E., Jun 15 2002, In : Blood. 99, 12, p. 4413-4421 9 p.

Research output: Contribution to journalArticle

36 Scopus citations

Cutting edge: IL-17D, a novel member of the IL-17 family, stimulates cytokine production and inhibits hemopoiesis

Starnes, T., Broxmeyer, H. E., Robertson, M. J. & Hromas, R., Jul 15 2002, In : Journal of Immunology. 169, 2, p. 642-646 5 p.

Research output: Contribution to journalArticle

Open Access
197 Scopus citations

Down-regulation of the myeloid homeobox protein Hex is essential for normal T-cell development

Mack, D. L., Leibowitz, D. S., Cooper, S., Ramsey, H., Broxmeyer, H. E. & Hromas, R., Dec 1 2002, In : Immunology. 107, 4, p. 444-451 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Enhancement of intracellular signaling associated with hematopoietic progenitor cell survival in response to SDF-1/CXCL12 in synergy with other cytokines

Lee, Y., Gotoh, A., Kwon, H. J., You, M., Kohli, L., Mantel, C., Cooper, S., Hangoc, G., Miyazawa, K., Ohyashiki, K. & Broxmeyer, H. E., Jun 15 2002, In : Blood. 99, 12, p. 4307-4317 11 p.

Research output: Contribution to journalArticle

130 Scopus citations

Immune responses in 4-1BB (CD137)-deficient mice

Kwon, B. S., Hurtado, J. C., Lee, Z. H., Kwack, K. B., Seo, S. K., Choi, B. K., Koller, B. H., Wolisi, G., Broxmeyer, H. E. & Vinay, D. S., Jun 1 2002, In : Journal of Immunology. 168, 11, p. 5483-5490 8 p.

Research output: Contribution to journalArticle

Open Access
163 Scopus citations

P21waf-1-Chk1 pathway monitors G1 phase microtubule integrity and is crucial for restriction point transition.

Mantel, C. R., Gelfano, V. M., Kim, Y. J., McDaniel, A., Lee, Y., Boswell, H. S. & Broxmeyer, H. E., Jan 1 2002, In : Cell cycle (Georgetown, Tex.). 1, 5, p. 327-336 10 p.

Research output: Contribution to journalArticle

9 Scopus citations

Role of 4-1BB (CD 137) in the functional activation of cord blood CD28-CD8+ T cells

Kim, Y. J., Brutkiewicz, R. R. & Broxmeyer, H. E., Nov 1 2002, In : Blood. 100, 9, p. 3253-3260 8 p.

Research output: Contribution to journalArticle

36 Scopus citations
15 Scopus citations

Th1 cells regulate hematopoietic progenitor cell homeostasis by production of Oncostatin M

Broxmeyer, H. E., Bruns, H. A., Zhang, S., Cooper, S., Hangoc, G., McKenzie, A. N. J., Dent, A. L., Schindler, U., Naeger, L. K., Hoey, T. & Kaplan, M. H., Jan 1 2002, In : Immunity. 16, 6, p. 815-825 11 p.

Research output: Contribution to journalArticle

63 Scopus citations

The chemokine CCL21 protects normal marrow progenitors from ara-C cytotoxicity

Hromas, R., Cooper, S. & Broxmeyer, H. E., Sep 12 2002, In : Cancer Chemotherapy and Pharmacology. 50, 2, p. 163-166 4 p.

Research output: Contribution to journalArticle

3 Scopus citations

The effects of the Fanconi anemia zinc finger (FAZF) on cell cycle, apoptosis, and proliferation are differentiation stage-specific

Dai, M. S., Chevallier, N., Stone, S., Heinrich, M. C., McConnell, M., Reuter, T., Broxmeyer, H. E., Licht, J. D., Lu, L. & Hoatlin, M. E., Jul 19 2002, In : Journal of Biological Chemistry. 277, 29, p. 26327-26334 8 p.

Research output: Contribution to journalArticle

25 Scopus citations
2001

Blocking of c-FLIPL-independent cycloheximide-induced apoptosis or Fas-mediated apoptosis by the CC chemokine receptor 9/TECK interaction

Youn, B. S., Kim, Y. J., Mantel, C., Yu, K. Y. & Broxmeyer, H. E., Aug 15 2001, In : Blood. 98, 4, p. 925-933 9 p.

Research output: Contribution to journalArticle

55 Scopus citations

Chemokine regulation of hematopoiesis and the involvement of pertussis toxin-sensitive Gαi proteins

Broxmeyer, H. E., Youn, B. S., Kim, C., Hangoc, G., Cooper, S. & Mantel, C., Jan 1 2001, In : Annals of the New York Academy of Sciences. 938, p. 117-128 12 p.

Research output: Contribution to journalArticle

21 Scopus citations

Current status of cord blood banking and transplantation in the United States and Europe

Ballen, K., Broxmeyer, H. E., McCullough, J., Piaciabello, W., Rebulla, P., Verfaillie, C. M. & Wagner, J. E., Jan 1 2001, In : Biology of Blood and Marrow Transplantation. 7, 12, p. 635-645 11 p.

Research output: Contribution to journalArticle

Open Access
65 Scopus citations

Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production

Starnes, T., Robertson, M. J., Sledge, G., Kelich, S., Nakshatri, H., Broxmeyer, H. E. & Hromas, R., Oct 15 2001, In : Journal of Immunology. 167, 8, p. 4137-4140 4 p.

Research output: Contribution to journalArticle

Open Access
279 Scopus citations
6 Scopus citations
1 Scopus citations

Mzf1 controls cell proliferation and tumorigenesis

Gaboli, M., Kotsi, P. A., Gurrieri, C., Cattoretti, G., Ronchetti, S., Cordon-Cardo, C., Broxmeyer, H. E., Hromas, R. & Pandolfi, P. P., Jul 1 2001, In : Genes and Development. 15, 13, p. 1625-1630 6 p.

Research output: Contribution to journalArticle

104 Scopus citations

Regulation of hematopoiesis by chemokine family members

Broxmeyer, H. E., Jan 1 2001, In : International Journal of Hematology. 74, 1, p. 9-17 9 p.

Research output: Contribution to journalArticle

72 Scopus citations

Steel factor regulates cell cycle asymmetry

Mantel, C., Hendrie, P. & Broxmeyer, H. E., Jan 1 2001, In : Stem Cells. 19, 6, p. 483-491 9 p.

Research output: Contribution to journalArticle

13 Scopus citations
6 Scopus citations

The interphase microtubule damage checkpoint defines an S-phase commitment point and does not require p21waf-1

Mantel, C. R., Braun, S. E., Lee, Y., Kim, Y. J. & Broxmeyer, H. E., Mar 1 2001, In : Blood. 97, 5, p. 1505-1507 3 p.

Research output: Contribution to journalArticle

7 Scopus citations

Transcriptional and ERK1/2-dependent synergistic upregulation of p21cip1/waf1associated with steel factor synergy in MO7e

Lee, Y., Mantel, C., Anzai, N., Braun, S. E. & Broxmeyer, H. E., Jan 26 2001, In : Biochemical and Biophysical Research Communications. 280, 3, p. 675-683 9 p.

Research output: Contribution to journalArticle

18 Scopus citations
2000

Analysis of engraftment, graft-versus-host disease, and immune recovery following unrelated donor cord blood transplantation

Thomson, B. G., Robertson, K. A., Gowan, D., Heilman, D., Broxmeyer, H. E., Emanuel, D., Kotylo, P., Brahmi, Z. & Smith, F. O., Oct 15 2000, In : Blood. 96, 8, p. 2703-2711 9 p.

Research output: Contribution to journalArticle

206 Scopus citations
29 Scopus citations

CD8+ NKT Cells, low in cord blood, preferentially require 4-1bb rather than cd28 for costimulation

Kim, Y. J. & Broxmeyer, H. E., Dec 1 2000, In : Blood. 96, 11 PART I, p. 240a

Research output: Contribution to journalArticle

3 Scopus citations

Chemokine receptor ccr9-mediated resistance to fas-induced apoptosis via teck is pi3 kinase-dependent but mapk- independent

Youn, B. S., Kim, Y. J. & Broxmeyer, H. E., Dec 1 2000, In : Blood. 96, 11 PART I, p. 238a

Research output: Contribution to journalArticle

Co-transduction of cDNAs for c-kit and steel factor into single CD34+ cord blood cells further enhances the growth of erythroid and multipotential progenitors

Lu, L., Dai, M. S., Ge, Y., Wang, L. S., Braun, S. E., Wait, C. L., Griffith, D. J., Heinrich, M. C. & Broxmeyer, H. E., Dec 1 2000, In : Journal of Hematotherapy and Stem Cell Research. 9, 6, p. 813-825 13 p.

Research output: Contribution to journalArticle

3 Scopus citations

Development of a transgenic mouse that overexpresses a novel product of the growth hormone-releasing hormone gene

Fang, S., Steinmetz, R., King, D. W., Zeng, P., Vogelweid, C., Cooper, S., Hangcoc, G., Broxmeyer, H. E. & Pescovitz, O. H., Jan 1 2000, In : Endocrinology. 141, 4, p. 1377-1383 7 p.

Research output: Contribution to journalArticle

Open Access
8 Scopus citations

Differentially expressed genes during in vitro differentiation of murine embryonic stem cells transduced with a human erythropoietin receptor cDNA

Xia, Z. B., Dai, M. S., Magoulas, C., Broxmeyer, H. E. & Lu, L., Dec 2 2000, In : Journal of Hematotherapy and Stem Cell Research. 9, 5, p. 651-658 8 p.

Research output: Contribution to journalArticle

14 Scopus citations
Open Access
3 Scopus citations
3 Scopus citations

Essential role of signal transducer and activator of transcription (Stat)5a but not Stat5b for Flt3-dependent signaling

Zhang, S., Fukuda, S., Lee, Y., Hangoc, G., Cooper, S., Spolski, R., Leonard, W. J. & Broxmeyer, H. E., Sep 4 2000, In : Journal of Experimental Medicine. 192, 5, p. 719-728 10 p.

Research output: Contribution to journalArticle

169 Scopus citations

Expression and activation of caspase-3/CPP32 in CD34+ cord blood cells is linked to apoptosis after growth factor withdrawal

Wang, L. S., Liu, H. J., Xia, Z. B., Broxmeyer, H. E. & Lu, L., Aug 1 2000, In : Experimental Hematology. 28, 8, p. 907-915 9 p.

Research output: Contribution to journalArticle

27 Scopus citations