Hal Broxmeyer

  • 41168 Citations
  • 99 h-Index
1973 …2020

Research output per year

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Publications

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Article
1994
7 Scopus citations

Myelosuppressive effects in vivo with very low dosages of monomeric recombinant murine macrophage inflammatory protein-1α

Cooper, S., Mantel, C. & Broxmeyer, H. E., Jan 1 1994, In : Experimental Hematology. 22, 2, p. 186-193 8 p.

Research output: Contribution to journalArticle

44 Scopus citations
25 Scopus citations

Proliferative and cytotoxic responses of human cord blood t lymphocytes following allogeneic stimulation

Risdon, G., Gaddy, J., Stehman, F. B. & Broxmeyer, H. E., Mar 1994, In : Cellular Immunology. 154, 1, p. 14-24 11 p.

Research output: Contribution to journalArticle

146 Scopus citations

Recombinant human Interleukin-1 Alpha: A potent bio-immunomodifier in vivo in immunosuppressed mice induced by cyclophosphamide, retroviral infection and surgical stress

Shen, R. N., Wu, B., Lu, L., Kaiser, H. E. & Broxmeyer, H. E., Jan 1 1994, In : In Vivo. 8, 1, p. 59-63 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

SCID mice as an in vivo model of human cord blood hematopoiesis

Vormoor, J., Lapidot, T., Pflumio, F., Risdon, G., Patterson, B., Broxmeyer, H. E. & Dick, J. E., Dec 1 1994, In : Blood Cells. 20, 2-3, p. 316-322 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

SH2-containing phosphotyrosine phosphatase Syp is a target of p210bcr-abl tyrosine kinase

Tauchi, T., Feng, G. S., Shen, R., Song, H. Y., Donner, D., Pawson, T. & Broxmeyer, H. E., May 27 1994, In : Journal of Biological Chemistry. 269, 21, p. 15381-15387 7 p.

Research output: Contribution to journalArticle

83 Scopus citations
14 Scopus citations

The ubiquitously expressed Syp phosphatase interacts with c-kit and Grb2 in hematopoietic cells

Tauchi, T., Feng, G. S., Marshall, M. S., Shen, R., Mantel, C., Pawson, T. & Broxmeyer, H. E., Oct 7 1994, In : Journal of Biological Chemistry. 269, 40, p. 25206-25211 6 p.

Research output: Contribution to journalArticle

132 Scopus citations
1993

Adeno-associated virus 2-mediated gene transfer in murine hematopoietic progenitor cells

Zhen Zhou, S., Broxmeyer, H. E., Cooper, S., Harrington, M. A. & Srivastava, A., Dec 1 1993, In : Experimental Hematology. 21, 7, p. 928-933 6 p.

Research output: Contribution to journalArticle

67 Scopus citations

Antitumor effect of interleukin 7 in combination with local hyperthermia in mice bearing B16a melanoma cells

Wu, B., Shen, RN. N., Wang, WX. X., Broxmeyer, H. E. & Lu, L., 1993, In : STEM CELLS. 11, 5, p. 412-421 10 p.

Research output: Contribution to journalArticle

10 Scopus citations

Characterization of Cord Blood Stem/Progenitor Cells

Broxmeyer, H. E. & Carow, C. E., Jan 1 1993, In : Journal of Hematotherapy. 2, 2, p. 197-199 3 p.

Research output: Contribution to journalArticle

3 Scopus citations
10 Scopus citations
231 Scopus citations

Detection of human myeloid progenitor cells in a murine background

Carow, C. E., Harrington, M. A. & Broxmeyer, H. E., Dec 1 1993, In : Experimental Hematology. 21, 1, p. 66-69 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Differential responses of myeloid progenitor cells from patients with myeloid leukemia and myelodysplasia to the costimulating effects of steel factor in vitro

Maze, R., Horie, M., Hendrie, P., Vadhan-Raj, S., Tricot, G., Gordon, M., Nemunaitis, J., Ashman, L. K. & Broxmeyer, H. E., Dec 1 1993, In : Experimental Hematology. 21, 4, p. 545-551 7 p.

Research output: Contribution to journalArticle

15 Scopus citations

Enrichment, characterization, and responsiveness of single primitive CD34+++ human umbilical cord blood hematopoietic progenitors with high proliferative and replating potential

Lu, L., Xiao, M., Shen, R. N., Grigsby, S. & Broxmeyer, H. E., Jan 1 1993, In : Blood. 81, 1, p. 41-48 8 p.

Research output: Contribution to journalArticle

209 Scopus citations

Haemopoietic stem/progenitor cell transplant in Fanconi anaemia using HLA‐matched sibling umbilical cord blood cells

Kohli‐Kumar, M., Shahidi, N. T., Broxmeyer, H. E., Masterson, M., Delaat, C., Sambrano, J., Morris, C., Auerbach, A. D. & Harris, R. E., Oct 1993, In : British journal of haematology. 85, 2, p. 419-422 4 p.

Research output: Contribution to journalArticle

53 Scopus citations
Open Access
94 Scopus citations

High-Level Multilineage Engraftment of Human Cord Blood Cells in SCI Mice

Vormoor, J., Lapidot, T., Pflumio, F., Risdon, G., Patterson, B., Broxmeyer, H. E. & Dick, J. E., Jan 1 1993, In : Journal of Hematotherapy. 2, 2, p. 215-216 2 p.

Research output: Contribution to journalArticle

5 Scopus citations

Human interferon-inducible protein 10: Expression and purification of recombinant protein demonstrate inhibition of early human hematopoietic progenitors

Sarris, A. H., Broxmeyer, H. E., Wirthmueller, U., Karasavvas, N., Cooper, S., Lu, L. & Krueger, J., Sep 1 1993, In : Journal of Experimental Medicine. 178, 3, p. 1127-1132 6 p.

Research output: Contribution to journalArticle

Open Access
81 Scopus citations

Human multipotential progenitor cells (CFU-GEMM) have extensive replating capacity for secondary CFU-GEMM: An effect enhanced by cord blood plasma

Carow, C. E., Hangoc, G. & Broxmeyer, H. E., Jan 1 1993, In : Blood. 81, 4, p. 942-949 8 p.

Research output: Contribution to journalArticle

Open Access
89 Scopus citations

Introduction

Broxmeyer, H. E., Jan 1 1993, In : Journal of Hematotherapy. 2, 2, p. 195-196 2 p.

Research output: Contribution to journalArticle

In vivo effects of purified recombinant human macrophage colony- stimulating factor in combination with local hyperthermia on tumor progression in B16a melanoma bearing mice

Lu, L., Xiao, M., Wu, B., Wen Xe Wang, X. W., Wei Ren Yan, R. Y., Broxmeyer, H. E. & Shen, R. N., Jan 1 1993, In : International Journal of Hematology. 58, 3, p. 139-152 14 p.

Research output: Contribution to journalArticle

5 Scopus citations

In vivo effects of recombinant interleukin-11 on myelopoiesis in mice

Hangoc, G., Yin, T., Cooper, S., Schendel, P., Yu Chung Yang, C. Y. & Broxmeyer, H. E., Jan 1 1993, In : Blood. 81, 4, p. 965-972 8 p.

Research output: Contribution to journalArticle

Open Access
78 Scopus citations
30 Scopus citations

Kinetic selectivity of cholinephosphotransferase in mouse liver: The K(m) for CDP-choline depends on diacylglycerol structure

Mantel, C. R., Schulz, A. R., Miyazawa, K. & Broxmeyer, H. E., Jan 1 1993, In : Biochemical Journal. 289, 3, p. 815-820 6 p.

Research output: Contribution to journalArticle

15 Scopus citations

Macrophage inflammatory protein-1α rapidly modulates its receptors and inhibits the anti-CD3 mAb-mediated proliferation of T lymphocytes

Zhou, Z., Kim, Y. J., Pollok, K., Hurtado, J., Lee, J. K., Broxmeyer, H. E. & Kwon, B. S., Jan 1 1993, In : Journal of Immunology. 151, 8, p. 4333-4341 9 p.

Research output: Contribution to journalArticle

30 Scopus citations
Open Access
44 Scopus citations

Regulation of myelopoiesis by murine fibroblastic and adipogenic cell lines

Hangoc, G., Daub, L. R., Maze, R. G., Falkenburg, J. H. F., Broxmeyer, H. E. & Harrington, M. A., Dec 1 1993, In : Experimental Hematology. 21, 4, p. 502-507 6 p.

Research output: Contribution to journalArticle

14 Scopus citations
10 Scopus citations
1992

Abrogating chemotherapy-induced myelosuppression by recombinant granulocyte-macrophage colony-stimulating factor in patients with sarcoma: Protection at the progenitor cell level

Vadhan-Raj, S., Broxmeyer, H. E., Hittelman, W. N., Papadopoulos, N. E., Chawla, S. P., Fenoglio, C., Cooper, S., Stephen Buescher, E., Frenck, R. W., Hollan, A., Perkins, R. C., Scheule, R. K., Gutterman, J. U., Salem, P. & Benjamin, R. S., Jan 1 1992, In : Journal of Clinical Oncology. 10, 8, p. 1266-1277 12 p.

Research output: Contribution to journalArticle

99 Scopus citations

Clinical and biological aspects of human umbilical cord blood as a source of transplantable hematopoietic stem and progenitor cells

Broxmeyer, H. E., Hangoc, C. & Cooper, S., Jul 27 1992, In : Bone marrow transplantation. 9, SUPPL. 1, p. 7-10 4 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effects in vivo of recombinant human inhibin on myelopoiesis in mice

Hangoc, G., Carow, C. E., Schwall, R., Mason, A. J. & Broxmeyer, H. E., Jan 1 1992, In : Experimental Hematology. 20, 10, p. 1243-1246 4 p.

Research output: Contribution to journalArticle

6 Scopus citations

Growth characteristics and expansion of human umbilical cord blood and estimation of its potential for transplantation in adults

Broxmeyer, H. E., Hangoc, G., Cooper, S., Ribeiro, R. C., Graves, V., Yoder, M., Wagner, J., Vadhan-Raj, S., Benninger, L., Rubinstein, P. & Broun, E. R., Jan 1 1992, In : Proceedings of the National Academy of Sciences of the United States of America. 89, 9, p. 4109-4113 5 p.

Research output: Contribution to journalArticle

Open Access
413 Scopus citations

Increased osteoclast development after estrogen loss: Mediation by interleukin-6

Jilka, R. L., Hangoc, G., Girasole, G., Passeri, G., Williams, D. C., Abrams, J. S., Boyce, B., Broxmeyer, H. & Manolagas, S. C., Jan 1 1992, In : Science. 257, 5066, p. 88-91 4 p.

Research output: Contribution to journalArticle

1205 Scopus citations
23 Scopus citations

Influence of recombinant human interleukin (IL)‐7 on disease progression in mice infected with friend virus complex

Lu, L., Zhou, Z., Wu, B., Xiao, M., Shen, RN. N., Williams, D. E., Kim, YJ. J., Kwon, B. S., Ruscetti, S. & Broxmeyer, H. E., Sep 9 1992, In : International Journal of Cancer. 52, 2, p. 261-265 5 p.

Research output: Contribution to journalArticle

15 Scopus citations
3 Scopus citations

Myelosuppressive effects in vivo of purified recombinant murine macrophage inflammatory protein-1α

Maze, R., Sherry, B., Kwon, B. S., Cerami, A. & Broxmeyer, H. E., Jan 1 1992, In : Journal of Immunology. 149, 3, p. 1004-1009 6 p.

Research output: Contribution to journalArticle

63 Scopus citations

Recombinant human interleukin-9 induces protein tyrosine phosphorylation and synergizes with steel factor to stimulate proliferation of the human factor-dependent cell line, M07e

Miyazawa, K., Hendrie, P. C., Kim, Y. J., Mantel, C., Yang, Y. C., Byoung Se Kwon, S. K. & Broxmeyer, H. E., Jan 1 1992, In : Blood. 80, 7, p. 1685-1692 8 p.

Research output: Contribution to journalArticle

30 Scopus citations
51 Scopus citations

Transplantation of umbilical cord blood after myeloablative therapy: Analysis of engraftment

Wagner, J. E., Broxmeyer, H. E., Byrd, R. L., Zehnbauer, B., Schmeckpeper, B., Shah, N., Griffin, C., Emanuel, P. D., Zuckerman, K. S., Cooper, S., Carow, C., Bias, W. & Santos, G. W., Jan 1 1992, In : Blood. 79, 7, p. 1874-1881 8 p.

Research output: Contribution to journalArticle

Open Access
196 Scopus citations

Umbilical Cord and Placental Blood Hematopoietic Stem Cells: Collection, Cryopreservation, and Storage

Wagner, J. E., Broxmeyer, H. E. & Cooper, S., Jan 1 1992, In : Journal of Hematotherapy and Stem Cell Research. 1, 2, p. 167-173 7 p.

Research output: Contribution to journalArticle

41 Scopus citations
1991

Anti‐tumor effects of recombinant human macrophage colony‐stimulating factor, alone or in combination with local irradiation, in mice inoculated with lewis lung carcinoma cells

Lu, L., Shen, RN. N., Lin, ZH. H., Aukerman, S. L., Ralph, P. & Broxmeyer, H. E., Jan 2 1991, In : International Journal of Cancer. 47, 1, p. 143-147 5 p.

Research output: Contribution to journalArticle

27 Scopus citations

CD45 cell surface antigens are linked to stimulation of early human myeloid progenitor cells by interleukin 3 (IL-3), granulocyte/ macrophage colony-stimulating factor (GM-CSF), a GM-CSF/IL-3 fusion protein, and mast cell growth factor (a c-kit Ligand)

Broxmeyer, H. E., Lu, L., Hangoc, G., Cooper, S., Hendrie, P. C., Ledbetter, J. A., Xiao, M., Williams, D. E. & Shen, F. W., Aug 1 1991, In : Journal of Experimental Medicine. 174, 2, p. 447-458 12 p.

Research output: Contribution to journalArticle

Open Access
23 Scopus citations

Cloning and characterization of the murine promoter for the colony-stimulating factor-1-encoding gene

Harrington, M. A., Edenberg, H. J., Saxman, S., Pedigo, L. M., Daube, R. & Broxmeyer, H. E., Jun 30 1991, In : Gene. 102, 2, p. 165-170 6 p.

Research output: Contribution to journalArticle

39 Scopus citations
18 Scopus citations
11 Scopus citations
100 Scopus citations