Hal Broxmeyer

  • 41168 Citations
  • 99 h-Index
1973 …2020

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1991

Cure with low-dose total-body irradiation of the hematological disorder induced in mice with the Friend virus: Possible mechanism involving interferon-γ and Interleukin-2

Shen, R. N., Lu, L., Feng, G. S., Miller, J., Taylor, M. W. & Broxmeyer, H. E., Jan 1 1991, In : Lymphokine and Cytokine Research. 10, 1-2, p. 105-109 5 p.

Research output: Contribution to journalArticle

16 Scopus citations

Differential transcriptional and posttranscriptional regulation of gene expression of the colony-stimulating factors by interleukin-1 and fetal bovine serum in murine fibroblasts

Falkenburg, J. H. F., Harrington, M. A., De Paus, R. A., Walsh, W. K., Daub, R., Landegent, J. E. & Broxmeyer, H. E., Jan 1 1991, In : Blood. 78, 3, p. 658-665 8 p.

Research output: Contribution to journalArticle

39 Scopus citations

DNA amplification for DQ typing as an adjunct to serological prenatal HLA typing for the identification of potential donors for umbilical cord blood transplantation

Pollack, M. S., Auerbach, A. D., Broxmeyer, H. E., Zaafran, A., Griffith, R. L. & Erlich, H. A., Jan 1991, In : Human Immunology. 30, 1, p. 45-49 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Effect of murine mast cell growth factor (c-kit proto-oncogene ligand) on colony formation by human marrow hematopoietic progenitor cells

Broxmeyer, H. E., Cooper, S., Lu, L., Hangoc, G., Anderson, D., Cosman, D., Lyman, S. D. & Williams, D. E., Aug 15 1991, In : Blood. 77, 10, p. 2142-2149 8 p.

Research output: Contribution to journalArticle

138 Scopus citations

Effect of split low dose total body irradiation on SFFV mRNA, genomic DNA and protein expression in mice infected with the friend virus complex

Shen, R. N., Lu, L., Harrington, M. A., Srivastava, C., Kim, Y. J., Zhou, S. Z., Wu, B., Ruscetti, S. & Broxmeyer, H. E., Mar 1991, In : Leukemia. 5, 3, p. 225-229 5 p.

Research output: Contribution to journalArticle

7 Scopus citations

Effects in vivo of purified recombinant human activin and erythropoietin in mice

Broxmeyer, H. E., Hangoc, G., Zucali, J. R., Mason, A., Schwall, R., Carow, C. & Cooper, S., Dec 12 1991, In : International Journal of Hematology. 54, 6, p. 447-454 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Enhanced hematopoietic activity of a human granulocyte/macrophage colony-stimulating factor-interleukin 3 fusion protein

Curtis, B. M., Williams, D. E., Broxmeyer, H. E., Dunn, J., Farrah, T., Jeffery, E., Clevenger, W., Deroos, P., Martin, U., Friend, D., Craig, V., Gayle, R., Price, V., Cosman, D., March, C. J. & Park, L. S., Jul 1 1991, In : Proceedings of the National Academy of Sciences of the United States of America. 88, 13, p. 5809-5813 5 p.

Research output: Contribution to journalArticle

Open Access
123 Scopus citations

Hybrid cytokines as hematopoietic growth factors

Williams, D. E., Park, L. S., Broxmeyer, H. E. & Lu, L., 1991, In : The International Journal of Cell Cloning. 9, 6, p. 542-547 6 p.

Research output: Contribution to journalArticle

12 Scopus citations

Identification of cell surface receptors for murine macrophage inflammatory protein-1α

Oh, K. O., Zhou, Z., Kim, K. K., Samanta, H., Fraser, M., Kim, Y. J., Broxmeyer, H. E. & Kwon, B. S., Jan 1 1991, In : Journal of Immunology. 147, 9, p. 2978-2983 6 p.

Research output: Contribution to journalArticle

28 Scopus citations

Influence of murine mast cell growth factor (c-kit ligand) on colony formation by mouse marrow hematopoietic progenitor cells

Broxmeyer, H. E., Hangoc, G., Cooper, S., Anderson, D., Cosman, D., Lyman, S. D. & Williams, D. E., Mar 20 1991, In : Experimental Hematology. 19, 2, p. 143-146 4 p.

Research output: Contribution to journalArticle

62 Scopus citations
15 Scopus citations
6 Scopus citations
10 Scopus citations

Lactoferrin-lipopolysaccharide interactions. Effect on lactoferrin binding to monocyte/macrophage-differentiated HL-60 cells

Miyazawa, K., Mantel, C., Lu, L., Morrison, D. C. & Broxmeyer, H. E., Jan 1 1991, In : Journal of Immunology. 146, 2, p. 723-729 7 p.

Research output: Contribution to journalArticle

82 Scopus citations

Macrophage inflammatory protein (MIP)-1β abrogates the capacity of MIP-1α to suppress myeloid progenitor cell growth

Broxmeyer, H. E., Sherry, B., Cooper, S., Ruscetti, F. W., Williams, D. E., Arosio, P., Kwon, B. S. & Cerami, A., Nov 8 1991, In : Journal of Immunology. 147, 8, p. 2586-2594 9 p.

Research output: Contribution to journalArticle

70 Scopus citations

Mast cell growth factor (c-kit ligand) enhances cytokine stimulation of proliferation of the human factor-dependent cell line, M07e

Hendrie, P. C., Miyazawa, K., Yang, Y. C., Langefeld, C. D. & Broxmeyer, H. E., Oct 22 1991, In : Experimental Hematology. 19, 10, p. 1031-1037 7 p.

Research output: Contribution to journalArticle

102 Scopus citations

Mast cell growth factor (c-kit ligand) supports the growth of human multipotential progenitor cells with a high replating potential

Carow, C. E., Hangoc, G., Cooper, S. H., Williams, D. E. & Broxmeyer, H. E., Dec 9 1991, In : Blood. 78, 9, p. 2216-2221 6 p.

Research output: Contribution to journalArticle

104 Scopus citations
Open Access
62 Scopus citations
2 Scopus citations

Regulation of human bone marrow lactoferrin and myeloperoxidase gene expression by tumor necrosis factor-α

Srivastava, C. H., Rado, T. A., Bauerle, D. & Broxmeyer, H. E., Jan 1 1991, In : Journal of Immunology. 146, 3, p. 1014-1019 6 p.

Research output: Contribution to journalArticle

23 Scopus citations

Role of Transforming Growth Factor‐β1 in Regulation of Hematopoiesis

RUSCETTI, FRANCIS. W., JACOBSEN, STEN. E., BIRCHENALL‐ROBERTS, MARIA., BROXMEYER, HAL. E., ENGELMANN, GARY. L., DUBOIS, CLAIRE. & KELLER, JONATHAN. R., Jul 1991, In : Annals of the New York Academy of Sciences. 628, 1, p. 31-43 13 p.

Research output: Contribution to journalArticle

31 Scopus citations

Summary of meeting on negative regulators of hematopoiesis

Broxmeyer, H. E., Najman, A. & Dainiak, N., Mar 20 1991, In : Experimental Hematology. 19, 2, p. 149-152 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Synergistic effect of human lactoferrin and recombinant murine interferon-γ on disease progression in mice infected with the polycythemia-inducing strain of the Friend virus complex

Lu, L., Shen, R. N., Zhou, S. Z., Srivastava, C., Harrington, M., Miyazawa, K., Wu, B., Lin, Z. H., Ruscetti, S. & Broxmeyer, H. E., Jan 1 1991, In : International Journal of Hematology. 54, 2, p. 117-124 8 p.

Research output: Contribution to journalArticle

19 Scopus citations

Umbilical cord blood hematopoietic stem and repopulating cells in human clinical transplantation

Broxmeyer, H. E., Kurtzberg, J., Gluckman, E., Auerbach, A. D., Douglas, G., Cooper, S., Falkenburg, J. H. F., Bard, J. & Boyse, E. A., Jan 1 1991, In : Blood Cells. 17, 2, p. 313-329 17 p.

Research output: Contribution to journalArticle

169 Scopus citations

Whole body hyperthermia: A potent radioprotector in vivo

Shen, R. N., Hornback, N. B., Shidnia, H., Wu, B., Lu, L. & Broxmeyer, H. E., Mar 1991, In : International journal of radiation oncology, biology, physics. 20, 3, p. 525-530 6 p.

Research output: Contribution to journalArticle

43 Scopus citations
1990

Effect of myogenic and adipogenic differentiation on expression of colony-stimulating factor genes

Harrington, M. A., Frederik Falkenburg, J. H., Daub, R. & Broxmeyer, H. E., Sep 1990, In : Molecular and cellular biology. 10, 9, p. 4948-4952 5 p.

Research output: Contribution to journalArticle

Open Access
11 Scopus citations

Effects of Interleukin 2 Treatment Combined with Local Hyperthermia in Mice Inoculated with Lewis Lung Carcinoma Cells

Shen, R. N., Lu, L., Broxmeyer, H. E., Wu, B., Shidnia, H. & Hornback, N. B., Aug 15 1990, In : Cancer Research. 50, 16, p. 5027-5030 4 p.

Research output: Contribution to journalArticle

17 Scopus citations

Ehancing and suppressing effects of recombinant murine macrophage inflammatory proteins on colony formation in vitro by bone marrow myeloid progenitor cells

Broxmeyer, H. E., Sherry, B., Lu, L., Cooper, S., Oh, K. O., Tekamp-Olson, P., Kwon, B. S. & Cerami, A., Jan 1 1990, In : Blood. 76, 6, p. 1110-1116 7 p.

Research output: Contribution to journalArticle

197 Scopus citations

Enhanced stimulation of human bone marrow macrophage colony formation in vitro by recombinant human macrophage colony-stimulating factor in agarose medium and at low oxygen tension

Broxmeyer, H. E., Cooper, S., Lu, L., Miller, M. E., Langefeld, C. D. & Ralph, P., Jan 1 1990, In : Blood. 76, 2, p. 323-329 7 p.

Research output: Contribution to journalArticle

47 Scopus citations
39 Scopus citations

Human umbilical cord blood: A clinically useful source of transplantable hematopoietic stem/progenitor cells

Broxmeyer, H. E., Cooper, S., Hangoc, G., Gluckman, E., Auerbach, A., Douglas, G. W., Friedman, H., Kurtzberg, J., Bard, J. & Boyse, E. A., 1990, In : The International Journal of Cell Cloning. 8, 1 S, p. 76-91 16 p.

Research output: Contribution to journalArticle

132 Scopus citations

Influence of interleukins 3, 5, and 6 on the growth of eosinophil progenitors in highly enriched human bone marrow in the absence of serum

Lu, L., Lin, Z. H., Shen, R. N., Warren, D. J., Leemhuis, T. & Broxmeyer, H. E., Dec 1 1990, In : Experimental Hematology. 18, 11, p. 1180-1186 7 p.

Research output: Contribution to journalArticle

13 Scopus citations
12 Scopus citations

Prenatal identification of potential donors for umbilical cord blood transplantation for Fanconi anemia

Auerbach, A. D., Ghosh, R., Pollack, M. S., Douglas, G. W. & Broxmeyer, H. E., Oct 1990, In : Transfusion. 30, 8, p. 682-687 6 p.

Research output: Contribution to journalArticle

46 Scopus citations

Stimulation of myelopoiesis in a patient with congenital neutropenia: Biology and nature of response to recombinant human granulocyte-macrophage colony-stimulating factor

Vadhan-Raj, S., Jeha, S. S., Buescher, S., LeMaistre, A., Yee, G., Lu, L., Lloreta, J., Hoots, W. K., Hittelman, W. N., Gutterman, J. U. & Broxmeyer, H. E., Jan 1 1990, In : Blood. 75, 4, p. 858-864 7 p.

Research output: Contribution to journalArticle

23 Scopus citations

T-cell growth factor P40 promotes the proliferation of myeloid cell lines and enhances erythroid burst formation by normal murine bone marrow cells in vitro

Williams, D. E., Morrissey, P. J., Mochizuki, D. Y., De Vries, P., Anderson, D., Cosman, D., Boswell, H. S., Cooper, S., Grabstein, K. H. & Broxmeyer, H. E., Jan 1 1990, In : Blood. 76, 5, p. 906-911 6 p.

Research output: Contribution to journalArticle

39 Scopus citations

Transplantation of umbilical cord blood in Fanconi's anemia

Gluckman, E., Devergie, A., Bourdeau-Esperou, H., Thierry, D., Traineau, R., Auerbach, A. & Broxmeyer, H. E., Dec 1 1990, In : Nouvelle Revue Francaise d'Hematologie. 32, 6, p. 423-425 3 p.

Research output: Contribution to journalArticle

48 Scopus citations
1989
15 Scopus citations
47 Scopus citations

Effect in Vivo of Multiple Injections of Purified Murine and Recombinant Human Macrophage Colony-stimulating Factor to Mice

Chikkappa, G., Broxmeyer, H. E., Cooper, S., Williams, D. E., Hangoc, G., Greenberg, M. L., Waheed, A. & Shadduck, R. K., Jul 1 1989, In : Cancer Research. 49, 13, p. 3558-3561 4 p.

Research output: Contribution to journalArticle

13 Scopus citations
1 Scopus citations

Effects of recombinant human colony stimulating factors (CSF) (granulocyte-macrophage CSF, granulocyte CSF, and CSF-1) on human monocyte/macrophage differentiation

Geissler, K., Harrington, M., Srivastava, C., Leemhuis, T., Tricot, G. & Broxmeyer, H. E., Jan 1 1989, In : Journal of Immunology. 143, 1, p. 140-146 7 p.

Research output: Contribution to journalArticle

66 Scopus citations

Hematopoietic Reconstitution in a Patient with Fanconi's Anemia by Means of Umbilical-Cord Blood from an HLA-Identical Sibling

Gluckman, E., Broxmeyer, H. E., Auerbach, A. D., Friedman, H. S., Douglas, G. W., Devergie, A., Esperou, H., Thierry, D., Socie, G., Lehn, P., Cooper, S., English, D., Kurtzberg, J., Bard, J. & Boyse, E. A., Oct 26 1989, In : New England Journal of Medicine. 321, 17, p. 1174-1178 5 p.

Research output: Contribution to journalArticle

1606 Scopus citations

Human umbilical cord blood as a potential source of transplantable hematopoietic stem/progenitor cells

Broxmeyer, H. E., Douglas, G. W., Hangoc, G., Cooper, S., Bard, J., English, D., Arny, M., Thomas, L. & Boyse, E. A., Jan 1 1989, In : Proceedings of the National Academy of Sciences of the United States of America. 86, 10, p. 3828-3832 5 p.

Research output: Contribution to journalArticle

Open Access
931 Scopus citations

Influence of IL-1α and -1β on the survival of human bone marrow cells responding to hematopoietic colony-stimulating factors

Hangoc, G., Williams, D. E., Falkenburg, J. H. F. & Broxmeyer, H. E., Jan 1 1989, In : Journal of Immunology. 142, 12, p. 4329-4334 6 p.

Research output: Contribution to journalArticle

19 Scopus citations

Influence of purified recombinant human macrophage colony stimulating factor in mice.

Broxmeyer, H. E., Geissler, K., Cooper, S. & Williams, D. E., Jan 1 1989, In : Biotechnology therapeutics. 1, 1, p. 43-54 12 p.

Research output: Contribution to journalArticle

2 Scopus citations

In Vivo Biologic Activities of Recombinant Human Granulocyte‐Macrophage Colony‐Stimulating Factor

VADHAN‐RAJ, SAROJ., HITTELMAN, WALTER. N., BROXMEYER, HAL. E., KEATING, MICHAEL., URDAL, DAVID. & GUTTERMAN, JORDAN. U., May 1989, In : Annals of the New York Academy of Sciences. 554, 1, p. 231-240 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Lactoferrin decreases monocyte-induced fibroblast production of myeloid colony-stimulating activity by suppressing monocyte release of interleukin-1

Zucali, J. R., Broxmeyer, H. E., Levy, D. & Morse, C., Jan 1 1989, In : Blood. 74, 5, p. 1531-1536 6 p.

Research output: Contribution to journalArticle

84 Scopus citations

Low dose total body irradiation: a potent anti-retroviral agent in vivo

Shen, R. N., Hornback, N. B., Lu, L., Chen, L. T., Brahmi, Z. & Broxmeyer, H. E., Jan 1989, In : International journal of radiation oncology, biology, physics. 16, 1, p. 165-170 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Myelopoietic enhancing effects of murine macrophage inflammatory proteins 1 and 2 on colony formation in vitro by murine and human bone marrow granulocyte/macrophage progenitor cells

Broxmeyer, H. E., Sherry, B., Lu, L., Cooper, S., Carow, C., Wolpe, S. D. & Cerami, A., Jan 1 1989, In : Journal of Experimental Medicine. 170, 5, p. 1583-1594 12 p.

Research output: Contribution to journalArticle

Open Access
81 Scopus citations