• 8146 Citations
  • 44 h-Index
20002019
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Publications 2000 2019

  • 8146 Citations
  • 44 h-Index
  • 109 Article
  • 2 Comment/debate
  • 2 Letter
  • 1 Conference contribution
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Article
2019
1 Citation (Scopus)

Loss of function of NCOR1 and NCOR2 impairs memory through a novel GABAergic hypothalamus–CA3 projection

DDD study, Feb 1 2019, In : Nature Neuroscience. 22, 2, p. 205-217 13 p.

Research output: Contribution to journalArticle

Lateral Hypothalamic Area
GABAergic Neurons
Co-Repressor Proteins
Memory Disorders
gamma-Aminobutyric Acid
4 Citations (Scopus)

No Gains in Long-term Survival After Liver Transplantation Over the Past Three Decades

Rana, A., Ackah, R. L., Webb, G. J., Halazun, K. J., Vierling, J. M., Liu, H., Wu, M. F., Yoeli, D., Kueht, M., Mindikoglu, A. L., Sussman, N. L., Galván, N. T., Cotton, R. T., O'Mahony, C. A. & Goss, J. A., Jan 1 2019, In : Annals of surgery. 269, 1, p. 20-27 8 p.

Research output: Contribution to journalArticle

Liver Transplantation
Survival
Immunosuppression
Transplants
Survivors

Using a monotone single-index model to stabilize the propensity score in missing data problems and causal inference

Qin, J., Yu, T., Li, P., Liu, H. & Chen, B., Apr 15 2019, In : Statistics in Medicine. 38, 8, p. 1442-1458 17 p.

Research output: Contribution to journalArticle

Single-index Model
Propensity Score
Causal Inference
Missing Data
Monotone

Using degradation-with-jump measures to estimate life characteristics of lithium-ion battery

Shu, Y., Feng, Q. & Liu, H., Nov 1 2019, In : Reliability Engineering and System Safety. 191, 106515.

Research output: Contribution to journalArticle

Degradation
Maximum likelihood estimation
Time series
Statistical methods
Lithium-ion batteries
2018
1 Citation (Scopus)

Asian elephant T cell responses to elephant endotheliotropic herpesvirus

Fuery, A., Leen, A. M., Peng, R., Wong, M. C., Liu, H. & Ling, P. D., Mar 1 2018, In : Journal of virology. 92, 6, e01951-17.

Research output: Contribution to journalArticle

Open Access
Elephantid herpesvirus 1
Elephas maximus
Herpesviridae
T-lymphocytes
T-Lymphocytes

Current Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphocytic Leukemia: Success, Failure and Future Perspectives—A Single-Center Experience, 2008 to 2016

Yanir, A. D., Martinez, C. A., Sasa, G., Leung, K., Gottschalk, S., Omer, B., Ahmed, N., Hegde, M., Eunji, J., Liu, H., Heslop, H. E., Brenner, M. K., Krance, R. A. & Naik, S., Jul 1 2018, In : Biology of Blood and Marrow Transplantation. 24, 7, p. 1424-1431 8 p.

Research output: Contribution to journalArticle

Hematopoietic Stem Cell Transplantation
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Tissue Donors
Pediatrics
Transplants

Dynamics of virus-specific T cell immunity in pediatric liver transplant recipients

Arasaratnam, R. J., Tzannou, I., Gray, T., Aguayo-Hiraldo, P. I., Kuvalekar, M., Naik, S., Gaikwad, A., Liu, H., Miloh, T., Vera, J. F., Himes, R. W., Munoz, F. M. & Leen, A. M., Sep 1 2018, In : American Journal of Transplantation. 18, 9, p. 2238-2249 12 p.

Research output: Contribution to journalArticle

Immunity
Immunosuppression
Pediatrics
Viruses
T-Lymphocytes
6 Citations (Scopus)

High Incidence of Autoimmune Disease after Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease

Yanir, A. D., Hanson, I. C., Shearer, W. T., Noroski, L. M., Forbes, L. R., Seeborg, F. O., Nicholas, S., Chinn, I., Orange, J. S., Rider, N. L., Leung, K. S., Naik, S., Carrum, G., Sasa, G., Hegde, M., Omer, B. A., Ahmed, N., Allen, C. E., Khaled, Y., Wu, M. F. & 6 others, Liu, H., Gottschalk, S. M., Heslop, H. E., Brenner, M. K., Krance, R. A. & Martinez, C. A., Aug 1 2018, In : Biology of Blood and Marrow Transplantation. 24, 8, p. 1643-1650 8 p.

Research output: Contribution to journalArticle

Chronic Granulomatous Disease
Hematopoietic Stem Cell Transplantation
Autoimmune Diseases
Incidence
Tissue Donors
9 Citations (Scopus)

Immunological Synapse Predicts Effectiveness of Chimeric Antigen Receptor Cells

Xiong, W., Chen, Y., Kang, X., Chen, Z., Zheng, P., Hsu, Y. H., Jang, J. H., Qin, L., Liu, H., Dotti, G. & Liu, D., Apr 4 2018, In : Molecular Therapy. 26, 4, p. 963-975 13 p.

Research output: Contribution to journalArticle

Open Access
Immunological Synapses
Antigen Receptors
T-Cell Antigen Receptor
Immunotherapy
Neoplasm Antigens
11 Citations (Scopus)

In Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas

Ramos, C. A., Rouce, R., Robertson, C. S., Reyna, A., Narala, N., Vyas, G., Mehta, B., Zhang, H., Dakhova, O., Carrum, G., Kamble, R. T., Gee, A. P., Mei, Z., Wu, M. F., Liu, H., Grilley, B., Rooney, C. M., Heslop, H. E., Brenner, M. K., Savoldo, B. & 1 others, Dotti, G., Dec 5 2018, In : Molecular Therapy. 26, 12, p. 2727-2737 11 p.

Research output: Contribution to journalArticle

B-Cell Lymphoma
Antigen Receptors
Non-Hodgkin's Lymphoma
T-Lymphocytes
B-Lymphocytes
3 Citations (Scopus)

Outcomes after Allogeneic Transplant in Patients with Wiskott-Aldrich Syndrome

Ngwube, A., Hanson, I. C., Orange, J., Rider, N. L., Seeborg, F., Shearer, W., Noroski, L., Nicholas, S., Forbes, L., Leung, K., Sasa, G., Naik, S., Hegde, M., Omer, B., Ahmed, N., Allen, C., Gottschalk, S., Wu, M. F., Liu, H., Brenner, M. & 3 others, Heslop, H., Krance, R. & Martinez, C., Mar 1 2018, In : Biology of Blood and Marrow Transplantation. 24, 3, p. 537-541 5 p.

Research output: Contribution to journalArticle

Open Access
Wiskott-Aldrich Syndrome
Chimerism
Transplants
Hematopoietic Stem Cell Transplantation
Tissue Donors

Predicting Liver Allograft Discard: The Discard Risk Index

Rana, A., Sigireddi, R. R., Halazun, K. J., Kothare, A., Wu, M. F., Liu, H., Kueht, M. L., Vierling, J. M., Sussman, N. L., Mindikoglu, A. L., Miloh, T., Galvan, N. T. N., Cotton, R. T., O'Mahony, C. A. & Goss, J. A., Sep 1 2018, In : Transplantation. 102, 9, p. 1520-1529 10 p.

Research output: Contribution to journalArticle

Allografts
Liver
Odds Ratio
Confidence Intervals
Bilirubin
1 Citation (Scopus)

Semiparametric probit models with univariate and bivariate current-status data

Liu, H. & Qin, J., Mar 1 2018, In : Biometrics. 74, 1, p. 68-76 9 p.

Research output: Contribution to journalArticle

Maximum likelihood estimation
Public health
Regression analysis
Numerical models
Statistical methods
37 Citations (Scopus)

Tumor-specific t-cells engineered to overcome tumor immune evasion induce clinical responses in patients with relapsed hodgkin lymphoma

Bollard, C. M., Tripic, T., Cruz, C. R., Dotti, G., Gottschalk, S., Torrano, V., Dakhova, O., Carrum, G., Ramos, C. A., Liu, H., Wu, M. F., Marcogliese, A. N., Barese, C., Zu, Y., Lee, D. Y., O’Connor, O., Gee, A. P., Brenner, M. K., Heslop, H. E. & Rooney, C. M., Apr 10 2018, In : Journal of Clinical Oncology. 36, 11, p. 1128-1139 12 p.

Research output: Contribution to journalArticle

Tumor Escape
Hodgkin Disease
T-Lymphocytes
Transforming Growth Factors
Neoplasms
2017

An oncology clinical trial design with randomization adaptive to both short- and long-term responses

Liu, H., Lin, X. & Huang, X., Jan 1 2017, (Accepted/In press) In : Statistical Methods in Medical Research.

Research output: Contribution to journalArticle

Oncology
Random Allocation
Randomisation
Clinical Trials
Survival
1 Citation (Scopus)

Are drowned donors marginal donors? A single pediatric center experience

Kumm, K. R., Galván, N. T. N., Koohmaraie, S., Rana, A., Kueht, M., Baugh, K., Liu, H., Yoeli, D., Cotton, R., O'Mahony, C. A. & Goss, J. A., Sep 1 2017, In : Pediatric Transplantation. 21, 6, e13009.

Research output: Contribution to journalArticle

Tissue Donors
Pediatrics
Craniocerebral Trauma
Allografts
Transplants
67 Citations (Scopus)

CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma

Heczey, A., Louis, C. U., Savoldo, B., Dakhova, O., Durett, A., Grilley, B., Liu, H., Wu, M. F., Mei, Z., Gee, A., Mehta, B., Zhang, H., Mahmood, N., Tashiro, H., Heslop, H. E., Dotti, G., Rooney, C. M. & Brenner, M. K., Sep 6 2017, In : Molecular Therapy. 25, 9, p. 2214-2224 11 p.

Research output: Contribution to journalArticle

Open Access
T-Cell Antigen Receptor
Neuroblastoma
Cyclophosphamide
Antigen Receptors
T-Lymphocytes
4 Citations (Scopus)

CD28 and 41BB costimulation enhances the effector function of CD19-specific engager T cells

Velasquez, M. P., Szoor, A., Vaidya, A., Thakkar, A., Nguyen, P., Wu, M. F., Liu, H. & Gottschalk, S., Oct 1 2017, In : Cancer Immunology Research. 5, 10, p. 860-870 11 p.

Research output: Contribution to journalArticle

T-Lymphocytes
Heterografts
Interleukin-2
B-Lymphocytes
Cell Proliferation
80 Citations (Scopus)

Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes

Ramos, C. A., Ballard, B., Zhang, H., Dakhova, O., Gee, A. P., Mei, Z., Bilgi, M., Wu, M. F., Liu, H., Grilley, B., Bollard, C. M., Chang, B. H., Rooney, C. M., Brenner, M. K., Heslop, H. E., Dotti, G. & Savoldo, B., Sep 1 2017, In : Journal of Clinical Investigation. 127, 9, p. 3462-3471 10 p.

Research output: Contribution to journalArticle

Open Access
Antigen Receptors
Lymphocytes
Anaplastic Large-Cell Lymphoma
Hodgkin Disease
T-Lymphocytes
2 Citations (Scopus)

C-MPL provides tumor-Targeted T-cell receptor-Transgenic T cells with costimulation and cytokine signals

Nishimura, C. D., Brenner, D. A., Mukherjee, M., Hirsch, R. A., Ott, L., Wu, M. F., Liu, H., Dakhova, O., Orange, J. S., Brenner, M. K., Lin, C. Y. & Arber, C., Dec 21 2017, In : Blood. 130, 25, p. 2739-2749 11 p.

Research output: Contribution to journalArticle

Open Access
T-cells
T-Cell Antigen Receptor
Tumors
Cytokines
T-Lymphocytes
27 Citations (Scopus)

Constitutive signaling from an engineered IL7 receptor promotes durable tumor elimination by tumor-redirected T cells

Shum, T., Omer, B., Tashiro, H., Kruse, R. L., Wagner, D. L., Parikh, K., Yi, Z., Sauer, T., Liu, D., Parihar, R., Castillo, P., Liu, H., Brenner, M. K., Metelitsa, L. S., Gottschalk, S. & Rooney, C. M., Nov 1 2017, In : Cancer Discovery. 7, 11, p. 1238-1247 10 p.

Research output: Contribution to journalArticle

Open Access
Interleukin-7 Receptors
T-Lymphocytes
Neoplasms
Interleukin-7
T-Cell Antigen Receptor

Generalized metabolic bone disease and fracture risk in Rothmund-Thomson syndrome

Cao, F., Lu, L., Abrams, S. A., Hawthorne, K. M., Tam, A., Jin, W., Dawson, B., Shypailo, R., Liu, H., Lee, B., Nagamani, S. C. S. & Wang, L. L., Aug 15 2017, In : Human Molecular Genetics. 26, 16, p. 3046-3055 10 p., ddx178.

Research output: Contribution to journalArticle

Open Access
Rothmund-Thomson Syndrome
Metabolic Bone Diseases
Bone Fractures
Bone Density
Bone and Bones
76 Citations (Scopus)

HER2-specific chimeric antigen receptor–modified virus-specific T cells for progressive glioblastoma: A phase 1 dose-escalation trial

Ahmed, N., Brawley, V., Hegde, M., Bielamowicz, K., Kalra, M., Landi, D., Robertson, C., Gray, T. L., Diouf, O., Wakefield, A., Ghazi, A., Gerken, C., Yi, Z., Ashoori, A., Wu, M. F., Liu, H., Rooney, C., Dotti, G., Gee, A., Su, J. & 13 others, Kew, Y., Baskin, D., Zhang, Y. J., New, P., Grilley, B., Stojakovic, M., Hicks, J., Powell, S. Z., Brenner, M. K., Heslop, H. E., Grossman, R., Wels, W. S. & Gottschalk, S., Aug 1 2017, In : JAMA Oncology. 3, 8, p. 1094-1101 8 p.

Research output: Contribution to journalArticle

Open Access
Glioblastoma
Antigen Receptors
Viruses
T-Lymphocytes
Antigens
10 Citations (Scopus)

Inferior Outcomes on the Waiting List in Low-Volume Pediatric Heart Transplant Centers

Rana, A., Fraser, C. D., Scully, B. B., Heinle, J. S., McKenzie, E. D., Dreyer, W. J., Kueht, M., Liu, H., Brewer, E. D., Rosengart, T. K., O'Mahony, C. A. & Goss, J. A., Jun 1 2017, In : American Journal of Transplantation. 17, 6, p. 1515-1524 10 p.

Research output: Contribution to journalArticle

Open Access
Cardiac Volume
Waiting Lists
Transplantation
Pediatrics
Transplants
84 Citations (Scopus)

Off-the-shelf virus-specific T cells to treat BK virus, human herpesvirus 6, cytomegalovirus, Epstein-Barr virus, and adenovirus infections after allogeneic hematopoietic stem-cell transplantation

Tzannou, I., Papadopoulou, A., Naik, S., Leung, K., Martinez, C. A., Ramos, C. A., Carrum, G., Sasa, G., Lulla, P., Watanabe, A., Kuvalekar, M., Gee, A. P., Wu, M. F., Liu, H., Grilley, B. J., Krance, R. A., Gottschalk, S., Brenner, M. K., Rooney, C. M., Heslop, H. E. & 2 others, Leen, A. M. & Omer, B., Nov 1 2017, In : Journal of Clinical Oncology. 35, 31, p. 3547-3557 11 p.

Research output: Contribution to journalArticle

BK Virus
Human Herpesvirus 6
Adenoviridae Infections
Epstein-Barr Virus Infections
Hematopoietic Stem Cell Transplantation
1 Citation (Scopus)

Poor outcomes for children on the wait list at low-volume kidney transplant centers in the United States

Rana, A., Brewer, E. D., Scully, B. B., Kueht, M. L., Goss, M., Halazun, K. J., Liu, H., Galvan, N. T. N., Cotton, R. T. & O’Mahony, C. A., Apr 1 2017, In : Pediatric Nephrology. 32, 4, p. 669-678 10 p.

Research output: Contribution to journalArticle

Transplants
Kidney
Organ Transplantation
Pediatrics
Tissue and Organ Procurement
21 Citations (Scopus)

Redirecting T cells to glypican-3 with 4-1BB zeta chimeric antigen receptors results in Th1 polarization and potent antitumor activity

Li, W., Guo, L., Rathi, P., Marinova, E., Gao, X., Wu, M. F., Liu, H., Dotti, G., Gottschalk, S., Metelitsa, L. S. & Heczey, A., May 1 2017, In : Human Gene Therapy. 28, 5, p. 437-448 12 p.

Research output: Contribution to journalArticle

Glypicans
Antigen Receptors
T-Cell Antigen Receptor
T-Lymphocytes
Neoplasms

Sample size calculations for prevalent cohort designs

Liu, H., Shen, Y., Ning, J. & Qin, J., Feb 1 2017, In : Statistical Methods in Medical Research. 26, 1, p. 280-291 12 p.

Research output: Contribution to journalArticle

Sample Size Calculation
Sample Size
Cohort Studies
Cohort Study
Design
27 Citations (Scopus)

Transgenic expression of IL15 improves antiglioma activity of IL13Rα2-CAR T cells but results in antigen loss variants

Krenciute, G., Prinzing, B. L., Yi, Z., Wu, M. F., Liu, H., Dotti, G., Balyasnikova, I. V. & Gottschalk, S., Jul 1 2017, In : Cancer Immunology Research. 5, 7, p. 571-581 11 p.

Research output: Contribution to journalArticle

Interleukin-15
Interleukin-13
T-Cell Antigen Receptor
Antigens
Antigen Receptors
1 Citation (Scopus)

Waiting list outcomes in pediatric lung transplantation: Poor results for children listed in adult transplant programs

Scully, B. B., Goss, M., Liu, H., Keuht, M. L., Adachi, I., McKenzie, E. D., Fraser, C. D., Melicoff, E., Mallory, G. B., Heinle, J. S. & Rana, A., Nov 1 2017, In : Journal of Heart and Lung Transplantation. 36, 11, p. 1201-1208 8 p.

Research output: Contribution to journalArticle

Waiting Lists
Lung Transplantation
Pediatrics
Transplants
Tissue and Organ Procurement
2016
28 Citations (Scopus)

Characterization and functional analysis of scFv-based chimeric antigen receptors to redirect T Cells to IL13Rα2-positive glioma

Krenciute, G., Krebs, S., Torres, D., Wu, M. F., Liu, H., Dotti, G., Li, X. N., Lesniak, M. S., Balyasnikova, I. V. & Gottschalk, S., Feb 1 2016, In : Molecular Therapy. 24, 2, p. 354-363 10 p.

Research output: Contribution to journalArticle

Open Access
Antigen Receptors
Glioma
T-Lymphocytes
Glioblastoma
T-Cell Antigen Receptor
78 Citations (Scopus)

Clinical responses with T lymphocytes targeting malignancy-associated κ light chains

Ramos, C. A., Savoldo, B., Torrano, V., Ballard, B., Zhang, H., Dakhova, O., Liu, E., Carrum, G., Kamble, R. T., Gee, A. P., Mei, Z., Wu, M. F., Liu, H., Grilley, B., Rooney, C. M., Brenner, M. K., Heslop, H. E. & Dotti, G., Jul 1 2016, In : Journal of Clinical Investigation. 126, 7, p. 2588-2596 9 p.

Research output: Contribution to journalArticle

Open Access
B-Lymphocytes
T-Lymphocytes
Light
Antigen Receptors
Neoplasms
5 Citations (Scopus)

Clonal dynamics in vivo of virus integration sites of T cells expressing a safety switch

Chang, E. C., Liu, H., West, J. A., Zhou, X., Dakhova, O., Wheeler, D. A., Heslop, H. E., Brenner, M. K. & Dotti, G., Apr 1 2016, In : Molecular Therapy. 24, 4, p. 736-745 10 p.

Research output: Contribution to journalArticle

Open Access
Virus Integration
Caspase 9
Dimerization
T-Lymphocytes
Safety
9 Citations (Scopus)

Lévy-driven non-Gaussian Ornstein–Uhlenbeck processes for degradation-based reliability analysis

Shu, Y., Feng, Q., Kao, E. P. C. & Liu, H., Nov 1 2016, In : IIE Transactions (Institute of Industrial Engineers). 48, 11, p. 993-1003 11 p.

Research output: Contribution to journalArticle

Reliability analysis
Degradation
Laplace transforms
Experiments
5 Citations (Scopus)

Semiparametric maximum likelihood inference for truncated or biased-sampling data

Liu, H., Ning, J., Qin, J. & Shen, Y., Jul 1 2016, In : Statistica Sinica. 26, 3, p. 1087-1115 29 p.

Research output: Contribution to journalArticle

Biased Sampling
Selection Bias
Likelihood Inference
Maximum Likelihood
Cox Regression Model
4 Citations (Scopus)

The optimal timing of surgical resection in high-risk neuroblastoma

Rojas, Y., Jaramillo, S., Lyons, K., Mahmood, N., Wu, M. F., Liu, H., Vasudevan, S. A., Guillerman, R. P., Louis, C. U., Russell, H. V., Nuchtern, J. G. & Kim, E. S., Oct 1 2016, In : Journal of Pediatric Surgery. 51, 10, p. 1665-1669 5 p.

Research output: Contribution to journalArticle

Neuroblastoma
Drug Therapy
Survival
Induction Chemotherapy
Nonparametric Statistics
31 Citations (Scopus)

The TGF-β/SMAD pathway is an important mechanism for NK cell immune evasion in childhood B-acute lymphoblastic leukemia

Rouce, R. H., Shaim, H., Sekine, T., Weber, G., Ballard, B., Ku, S., Barese, C., Murali, V., Wu, M. F., Liu, H., Shpall, E. J., Bollard, C. M., Rabin, K. R. & Rezvani, K., Apr 1 2016, In : Leukemia. 30, 4, p. 800-811 12 p.

Research output: Contribution to journalArticle

Immune Evasion
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Natural Killer Cells
Intercellular Signaling Peptides and Proteins
Neoplasms
2015
15 Citations (Scopus)

A phase 2 study of bortezomib in combination with ifosfamide/vinorelbine in paediatric patients and young adults with refractory/recurrent Hodgkin lymphoma: A Children's Oncology Group study

Horton, T. M., Drachtman, R. A., Chen, L., Cole, P. D., Mccarten, K., Voss, S., Guillerman, R. P., Buxton, A., Howard, S. C., Hogan, S. M., Sheehan, A. M., López-Terrada, D., Mrazek, M. D., Agrawal, N., Wu, M. F., Liu, H., De Alarcon, P. A., Trippet, T. M. & Schwartz, C. L., Jul 1 2015, In : British Journal of Haematology. 170, 1, p. 118-122 5 p.

Research output: Contribution to journalArticle

Ifosfamide
Hodgkin Disease
Young Adult
Confidence Intervals
Pediatrics
49 Citations (Scopus)

CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo

Hanley, P. J., Melenhorst, J. J., Nikiforow, S., Scheinberg, P., Blaney, J. W., Demmler-Harrison, G., Cruz, C. R., Lam, S., Krance, R. A., Leung, K. S., Martinez, C. A., Liu, H., Douek, D. C., Heslop, H. E., Rooney, C. M., Shpall, E. J., Barrett, A. J. & Bollard, C. M., Apr 29 2015, In : Science Translational Medicine. 7, 285, 285ra63.

Research output: Contribution to journalArticle

Cytomegalovirus
Epitopes
T-Lymphocytes
T-Lymphocyte Epitopes
Tissue Donors
160 Citations (Scopus)

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes

Caruana, I., Savoldo, B., Hoyos, V., Weber, G., Liu, H., Kim, E. S., Ittmann, M. M., Marchetti, D. & Dotti, G., May 1 2015, In : Nature Medicine. 21, 5, p. 524-529 6 p.

Research output: Contribution to journalArticle

Antigen Receptors
T-cells
T-Cell Antigen Receptor
Infiltration
Tumors
314 Citations (Scopus)

Human epidermal growth factor receptor 2 (HER2) - Specific chimeric antigen receptor - Modified T cells for the immunotherapy of HER2-positive sarcoma

Ahmed, N., Brawley, V. S., Hegde, M., Robertson, C., Ghazi, A., Gerken, C., Liu, E., Dakhova, O., Ashoori, A., Corder, A., Gray, T., Wu, M. F., Liu, H., Hicks, J., Rainusso, N., Dotti, G., Mei, Z., Grilley, B., Gee, A., Rooney, C. M. & 6 others, Brenner, M. K., Heslop, H. E., Wels, W. S., Wang, L. L., Anderson, P. & Gottschalk, S., May 20 2015, In : Journal of Clinical Oncology. 33, 15, p. 1688-1696 9 p.

Research output: Contribution to journalArticle

T-Cell Antigen Receptor
Sarcoma
Immunotherapy
T-Lymphocytes
Neoplasms
92 Citations (Scopus)

Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation

Zhou, X., Dotti, G., Krance, R. A., Martinez, C. A., Naik, S., Kamble, R. T., Durett, A. G., Dakhova, O., Savoldo, B., Stasi, A. D., Spencer, D. M., Lin, Y. F., Liu, H., Grilley, B. J., Gee, A. P., Rooney, C. M., Heslop, H. E. & Brenner, M. K., Jun 25 2015, In : Blood. 125, 26, p. 4103-4113 11 p.

Research output: Contribution to journalArticle

Open Access
T-cells
Caspase 9
Stem Cell Transplantation
Stem cells
Suicide
2014
186 Citations (Scopus)

Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT

Papadopoulou, A., Gerdemann, U., Katari, U. L., Tzannou, I., Liu, H., Martinez, C., Leung, K., Carrum, G., Gee, A. P., Vera, J. F., Krance, R. A., Brenner, M. K., Rooney, C. M., Heslop, H. E. & Leen, A. M., Jun 25 2014, In : Science Translational Medicine. 6, 242, 242ra83.

Research output: Contribution to journalArticle

Human Herpesvirus 6
Human Herpesvirus 4
Immunocompromised Host
Viruses
T-Lymphocytes
96 Citations (Scopus)

Armed oncolytic virus enhances immune functions of chimeric antigen receptor-modified T cells in solid tumors

Nishio, N., Diaconu, I., Liu, H., Cerullo, V., Caruana, I., Hoyos, V., Bouchier-Hayes, L., Savoldo, B. & Dotti, G., Jul 24 2014, In : Cancer Research. 74, 18, p. 5195-5205 11 p.

Research output: Contribution to journalArticle

Open Access
Oncolytic Viruses
T-Cell Antigen Receptor
Neoplasms
Interleukin-15
Chemokine CCL5
174 Citations (Scopus)

Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15

Xu, Y., Zhang, M., Ramos, C. A., Durett, A., Liu, E., Dakhova, O., Liu, H., Creighton, C. J., Gee, A. P., Heslop, H. E., Rooney, C. M., Savoldo, B. & Dotti, G., Jun 12 2014, In : Blood. 123, 24, p. 3750-3759 10 p.

Research output: Contribution to journalArticle

Open Access
Interleukin-15
Interleukin-7
T-cells
Stem cells
Stem Cells
4 Citations (Scopus)

Efficacy of deferred dosing of granulocyte colony-stimulating factor in autologous hematopoietic transplantation for multiple myeloma

Cox, J. E., Campos, S., Wu, J., May, R., Liu, H., Ramos, C. A., Carrum, G., Heslop, H. E., Brenner, M. K. & Kamble, R. T., Feb 1 2014, In : Bone Marrow Transplantation. 49, 2, p. 219-222 4 p.

Research output: Contribution to journalArticle

Open Access
Autologous Transplantation
Granulocyte Colony-Stimulating Factor
Multiple Myeloma
Febrile Neutropenia
Costs and Cost Analysis
52 Citations (Scopus)

Interleukin-7 mediates selective expansion of tumor-redirected cytotoxic T lymphocytes (CTLs) without enhancement of regulatory T-cell inhibition

Perna, S. K., Pagliara, D., Mahendravada, A., Liu, H., Brenner, M. K., Savoldo, B. & Dotti, G., Jan 1 2014, In : Clinical Cancer Research. 20, 1, p. 131-139 9 p.

Research output: Contribution to journalArticle

Open Access
Interleukin-7
Antigen Receptors
Cytotoxic T-Lymphocytes
Regulatory T-Lymphocytes
Human Herpesvirus 4
86 Citations (Scopus)

Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy

Heczey, A., Liu, D., Tian, G., Courtney, A. N., Wei, J., Marinova, E., Gao, X., Guo, L., Yvon, E., Hicks, J., Liu, H., Dotti, G. & Metelitsa, L. S., Oct 30 2014, In : Blood. 124, 18, p. 2824-2833 10 p.

Research output: Contribution to journalArticle

Open Access
Antigen Receptors
Natural Killer T-Cells
T-cells
Immunotherapy
Neoplasms
79 Citations (Scopus)

Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene

Zhou, X., Di Stasi, A., Tey, S. K., Krance, R. A., Martinez, C., Leung, K. S., Durett, A. G., Wu, M. F., Liu, H., Leen, A. M., Savoldo, B., Lin, Y. F., Grilley, B. J., Gee, A. P., Spencer, D. M., Rooney, C. M., Heslop, H. E., Brenner, M. K. & Dotti, G., Jun 19 2014, In : Blood. 123, 25, p. 3895-3905 11 p.

Research output: Contribution to journalArticle

Open Access
Transplants
T-cells
Caspase 9
Stem cells
Transgenes
5 Citations (Scopus)

Low rate of infusional toxicity after expanded cord blood transplantation

Bear, A. S., Hanley, P. J., Bosque, D. M., Cruz, C. R., Kaur, I., Liu, H., Kebriaei, P., Hosing, C., Rezvani, K., Oran, B., De Lima, M. J., Bollard, C. M. & Shpall, E. J., Jan 1 2014, In : Cytotherapy. 16, 8, p. 1153-1157 5 p.

Research output: Contribution to journalArticle

Fetal Blood
Transplantation
Transplants
Premedication
Hematopoiesis