Harikrishna Nakshatri

  • 11806 Citations
  • 56 h-Index
1988 …2020

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1988

Functional role of BK virus tumor antigens in transformation

Nakshatri, H., Pater, M. M. & Pater, A., 1988, In : Journal of virology. 62, 12, p. 4613-4621 9 p.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Glucocorticoid-dependent oncogenic transformation by type 16 but not type 11 human papilloma virus DNA

Pater, M. M., Hughes, G. A., Hyslop, D. E., Nakshatri, H. & Pater, A., Jan 1 1988, In : Nature. 335, 6193, p. 832-835 4 p.

Research output: Contribution to journalArticle

123 Scopus citations
1990

Activity and enhancer binding factors for jc virus regulatory elements in differentiating embryonal carcinoma cells

Nakshatri, H., Pater, A. & Pater, M. M., Aug 1990, In : Virology. 177, 2, p. 784-789 6 p.

Research output: Contribution to journalArticle

16 Scopus citations

Ubiquitous and cell-type-specific protein interactions with human papillomavirus type 16 and type 18 enhancers

Nakshatri, H., Pater, M. M. & Pater, A., Sep 1990, In : Virology. 178, 1, p. 92-103 12 p.

Research output: Contribution to journalArticle

22 Scopus citations
1991

Activity and enhancer binding factors for BK virus regulatory elements in differentiating embryonal carcinoma cells

Nakshatri, H., Pater, M. M. & Pater, A., Jul 1991, In : Virology. 183, 1, p. 374-380 7 p.

Research output: Contribution to journalArticle

5 Scopus citations

A retinoic acid response element is present in the mouse cellular retinol binding protein I (mCRBPI) promoter

Smith, W. C., Nakshatri, H., Leroy, P., Rees, J. & Chambon, P., 1991, In : EMBO Journal. 10, 8, p. 2223-2230 8 p.

Research output: Contribution to journalArticle

182 Scopus citations
Open Access
169 Scopus citations
1992

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

Nagpal, S., Saunders, M., Kastner, P., Durand, B., Nakshatri, H. & Chambon, P., Sep 18 1992, In : Cell. 70, 6, p. 1007-1019 13 p.

Research output: Contribution to journalArticle

296 Scopus citations

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

Leid, M., Kastner, P., Lyons, R., Nakshatri, H., Saunders, M., Zacharewski, T., Chen, J. Y., Staub, A., Garnier, J. M., Mader, S. & Chambon, P., Jan 24 1992, In : Cell. 68, 2, p. 377-395 19 p.

Research output: Contribution to journalArticle

982 Scopus citations

Retinoid receptors and binding proteins

Lohnes, D., Dierich, A., Ghyselinck, N., Kastner, P., Lampron, C., LeMeur, M., Lufkin, T., Mendelsohn, C., Nakshatri, H. & Chambon, P., 1992, In : Journal of cell science. 103, SUPPL. 16, p. 69-76 8 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

The first 124 nucleotides of the E7 coding sequences of HPV16 can render the HPV11 genome transformation competent

Pater, M. M., Nakshatri, H., Kisaka, C. & Pater, A., Jan 1992, In : Virology. 186, 1, p. 348-351 4 p.

Research output: Contribution to journalArticle

5 Scopus citations
1993

RARs and RXRs: Evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo

Nagpal, S., Friant, S., Nakshatri, H. & Chambon, P., Jan 1 1993, In : EMBO Journal. 12, 6, p. 2349-2360 12 p.

Research output: Contribution to journalArticle

265 Scopus citations

Retinoic Acid Signal Transduction Pathways

LEID, MARK., KASTNER, PHILIPPE., DURAND, BÉATRICE., KRUST, ANDRÉE., LEROY, PIERRE., LYONS, RUTH., MENDELSOHN, CATHY., NAGPAL, SUNIL., NAKSHATRI, HARIKRISHNA., REIBEL, CORINNE., SAUNDERS, MICHAEL. & CHAMBON, PIERRE., Jun 1993, In : Annals of the New York Academy of Sciences. 684, 1, p. 19-34 16 p.

Research output: Contribution to journalArticle

46 Scopus citations
1994

Stage and tissue‐specific expression of the alcohol dehydrogenase 1 (Adh‐1) gene during mouse development

Vonesch, JL. L., Nakshatri, H., Philippe, M., Chambon, P. & Dollé, P., Mar 1994, In : Developmental Dynamics. 199, 3, p. 199-213 15 p.

Research output: Contribution to journalArticle

40 Scopus citations
119 Scopus citations
1995

Interaction of Oct-1 with TFIIB: Implications for a novel response elicited through the proximal octamer site of the lipoprotein lipase promoter

Nakshatri, H., Nakshatri, P. & Currie, R. A., Aug 18 1995, In : Journal of Biological Chemistry. 270, 33, p. 19613-19623 11 p.

Research output: Contribution to journalArticle

Open Access
58 Scopus citations
1996

CNI-1493 inhibits monocyte/macrophage tumor necrosis factor by suppression of translation efficiency

Cohen, P. S., Nakshatri, H., Dennis, J., Caragine, T., Bianchi, M., Cerami, A. & Tracey, K. J., Apr 30 1996, In : Proceedings of the National Academy of Sciences of the United States of America. 93, 9, p. 3967-3971 5 p.

Research output: Contribution to journalArticle

97 Scopus citations

Isolation of retinoic acid-repressed genes from P19 embryonal carcinoma cells

Nakshatri, H., Bouillet, P., Bhat-Nakshatri, P. & Chambon, P., Sep 26 1996, In : Gene. 174, 1, p. 79-84 6 p.

Research output: Contribution to journalArticle

27 Scopus citations

Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated by cellular redox

Nakshatri, H., Bhat-Nakshatri, P. & Currie, R. A., Nov 26 1996, In : Journal of Biological Chemistry. 271, 46, p. 28784-28791 8 p.

Research output: Contribution to journalArticle

82 Scopus citations
1997

Constitutive activation of NF-κB during progression of breast cancer to hormone-independent growth

Nakshatri, H., Bhat-Nakshatri, P., Martin, D. A., Goulet, R. J. & Sledge, G. W., Jul 1997, In : Molecular and cellular biology. 17, 7, p. 3629-3639 11 p.

Research output: Contribution to journalArticle

Open Access
692 Scopus citations

Differential effect of Nonidet P40 on DNA binding of transcription factors.

Nakshatri, H. & Bhat-Nakshatri, P., Jun 15 1997, In : Analytical biochemistry. 249, 1, p. 103-104 2 p.

Research output: Contribution to journalArticle

8 Scopus citations
1998

Binding and activation of the human aldehyde dehydrogenase 2 promoter by hepatocyte nuclear factor 4

Stewart, M. J., Dipple, K. M., Estonius, M., Nakshatri, H., Everett, L. M. & Crabb, D. W., Aug 20 1998, In : Biochimica et Biophysica Acta - Gene Structure and Expression. 1399, 2-3, p. 181-186 6 p.

Research output: Contribution to journalArticle

25 Scopus citations
81 Scopus citations
76 Scopus citations

Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase

Burgess, G. S., Williamson, E. A., Cripe, L. D., Litz-Jackson, S., Bhatt, J. A., Stanley, K., Stewart, M. J., Kraft, A. S., Nakshatri, H. & Boswell, H. S., Oct 1 1998, In : Blood. 92, 7, p. 2450-2460 11 p.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations
1999

Cloning of BRAK, a novel divergent CXC chemokine preferentially expressed in normal versus malignant cells

Hromas, R., Broxmeyer, H. E., Kim, C., Nakshatri, H., Christopherson, K., Azam, M. & Hou, Y. H., Feb 24 1999, In : Biochemical and Biophysical Research Communications. 255, 3, p. 703-706 4 p.

Research output: Contribution to journalArticle

143 Scopus citations

Negative regulation of transactivation function but not DNA binding of NF-κB and AP-1 by IκBβ1 in breast cancer cells

Newton, T. R., Patel, N. M., Bhat-Nakshatri, P., Stauss, C. R., Goulet, R. J. & Nakshatri, H., Jun 25 1999, In : Journal of Biological Chemistry. 274, 26, p. 18827-18835 9 p.

Research output: Contribution to journalArticle

59 Scopus citations
2000
57 Scopus citations

Paclitaxel sensitivity of breast cancer cells with constitutively active NF-κB is enhanced by IκBα super-repressor and parthenolide

Patel, N. M., Nozaki, S., Shortle, N. H., Bhat-Nakshatri, P., Newton, T. R., Rice, S., Gelfanov, V., Boswell, S. H., Goulet, R. J., Sledge, G. W. & Nakshatri, H., Aug 24 2000, In : Oncogene. 19, 36, p. 4159-4169 11 p.

Research output: Contribution to journalArticle

Open Access
249 Scopus citations

Repression of transforming-growth-factor-β-mediated transcription by nuclear factor κB

Nagarajan, R. P., Chen, F., Li, W., Vig, E., Harrington, M. A., Nakshatri, H. & Chen, Y., Jun 15 2000, In : Biochemical Journal. 348, 3, p. 591-596 6 p.

Research output: Contribution to journalArticle

102 Scopus citations
30 Scopus citations
2001

Cutting edge: IL-17F, a novel cytokine selectively expressed in activated T cells and monocytes, regulates angiogenesis and endothelial cell cytokine production

Starnes, T., Robertson, M. J., Sledge, G., Kelich, S., Nakshatri, H., Broxmeyer, H. E. & Hromas, R., Oct 15 2001, In : Journal of Immunology. 167, 8, p. 4137-4140 4 p.

Research output: Contribution to journalArticle

Open Access
281 Scopus citations

Fusion AML1 transcript in a radiation-associated leukemia results in a truncated inhibitory AML1 protein

Hromas, R., Busse, T., Carroll, A., Mack, D., Shopnick, R., Zhang, D. E., Nakshatri, H. & Richkind, K., Apr 1 2001, In : Blood. 97, 7, p. 2168-2170 3 p.

Research output: Contribution to journalArticle

33 Scopus citations

Phosphatidylinositol 3-kinase/AKT-mediated activation of estrogen receptor α: A new model for anti-estrogen resistance

Campbell, R. A., Bhat-Nakshatri, P., Patel, N. M., Constantinidou, D., Ali, S. & Nakshatri, H., Mar 30 2001, In : Journal of Biological Chemistry. 276, 13, p. 9817-9824 8 p.

Research output: Contribution to journalArticle

757 Scopus citations

Repression of GADD153/CHOP by NF-κB: A possible cellular defense against endoplasmic reticulum stress-induced cell death

Nozaki, S., Sledge, G. W. & Nakshatri, H., Apr 19 2001, In : Oncogene. 20, 17, p. 2178-2185 8 p.

Research output: Contribution to journalArticle

97 Scopus citations
36 Scopus citations

Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: Cooperation of akt with raf/erk leads to p65 nuclear factor kB-mediated antiapoptosis involving c-IAP2

Gelfanov, V. M., Burgess, G. S., Litz-Jackson, S., King, A. J., Marshall, M. S., Nakshatri, H. & Scott Boswell, H., Oct 15 2001, In : Blood. 98, 8, p. 2508-2517 10 p.

Research output: Contribution to journalArticle

36 Scopus citations
2002

Identification of signal transduction pathways involved in constitutive NF-kB activation in breast cancer cells

Bhat-Nakshatri, P., Sweeney, C. J. & Nakshatri, H., Jan 1 2002, In : Oncogene. 21, 13, p. 2066-2078 13 p.

Research output: Contribution to journalArticle

102 Scopus citations

Identification of signal transduction pathways involved in constitutive NF-κB activation in breast cancer cells

Bhat-Nakshatri, P., Sweeney, C. J. & Nakshatri, H., May 21 2002, In : Oncogene. 21, 13, p. 2066-2078 13 p.

Research output: Contribution to journalArticle

2003

Interleukin-1α Promotes Tumor Growth and Cachexia in MCF-7 Xenograft Model of Breast Cancer

Kumar, S., Kishimoto, H., Chua, H. L., Badve, S., Miller, K. D., Bigsby, R. M. & Nakshatri, H., Dec 2003, In : American Journal of Pathology. 163, 6, p. 2531-2541 11 p.

Research output: Contribution to journalArticle

55 Scopus citations

NF-κB promotes breast cancer cell migration and metastasis by inducing the expression of the chemokine receptor CXCR4

Helbig, G., Christopherson, K. W., Bhat-Nakshatri, P., Kumar, S., Kishimoto, H., Miller, K. D., Broxmeyer, H. E. & Nakshatri, H., Jun 13 2003, In : Journal of Biological Chemistry. 278, 24, p. 21631-21638 8 p.

Research output: Contribution to journalArticle

506 Scopus citations
2004
128 Scopus citations

Inhibiting proteasomal proteolysis sustains estrogen receptor-α activation

Fan, M., Nakshatri, H. & Nephew, K. P., Nov 1 2004, In : Molecular Endocrinology. 18, 11, p. 2603-2615 13 p.

Research output: Contribution to journalArticle

72 Scopus citations

Nuclear factor-κB is constitutively activated in prostate cancer in vitro and is overexpressed in prostatic intraepithelial neoplasia and adenocarcinoma of the prostate

Sweeney, C., Li, L., Shanmugam, R., Bhat-Nakshatri, P., Jayaprakasan, V., Baldridge, L. A., Gardner, T., Smith, M., Nakshatri, H. & Cheng, L., Aug 15 2004, In : Clinical Cancer Research. 10, 16, p. 5501-5507 7 p.

Research output: Contribution to journalArticle

147 Scopus citations

Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer

Curry, E. A., Murry, D. J., Yoder, C., Fife, K., Armstrong, V., Nakshatri, H., O'Connell, M. & Sweeney, C. J., Aug 1 2004, In : Investigational New Drugs. 22, 3, p. 299-305 7 p.

Research output: Contribution to journalArticle

89 Scopus citations

Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function

Bhat-Nakshatri, P., Campbell, R. A., Patel, N. M., Newton, T. R., King, A. J., Marshall, M. S., Ali, S. & Nakshatri, H., Feb 23 2004, In : British Journal of Cancer. 90, 4, p. 853-859 7 p.

Research output: Contribution to journalArticle

26 Scopus citations
2005

Differential effect of anti-apoptotic genes Bcl-xL and c-FLIP on sensitivity of MCF-7 breast cancer cells to paclitaxel and docetaxel

Wang, Z., Goulet, R., Stanton, K. J., Sadaria, M. & Nakshatri, H., May 1 2005, In : Anticancer Research. 25, 3 C, p. 2367-2379 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Parthenolide and sulindac cooperate to mediate growth suppression and inhibit the nuclear factor-κB pathway in pancreatic carcinoma cells

Yip-Schneider, M. T., Nakshatri, H., Sweeney, C. J., Marshall, M. S., Wiebke, E. A. & Schmidt, C. M., Apr 2005, In : Molecular cancer therapeutics. 4, 4, p. 587-594 8 p.

Research output: Contribution to journalArticle

104 Scopus citations

The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells

Wollmann, W., Goodman, M. L., Bhat-Nakshatri, P., Kishimoto, H., Goulet, R. J., Mehrotra, S., Morimiya, A., Badve, S. & Nakshatri, H., 2005, In : Carcinogenesis. 26, 5, p. 900-907 8 p.

Research output: Contribution to journalArticle

37 Scopus citations