Harikrishna Nakshatri

  • 11854 Citations
  • 56 h-Index
1988 …2020

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Publications

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PROGgeneV2: Enhancements on the existing database

Goswami, C. P. & Nakshatri, H., Dec 17 2014, In : BMC Cancer. 14, 1, 970.

Research output: Contribution to journalArticle

183 Scopus citations
20 Scopus citations

Prognostic impact of ALDH1 in breast cancer: A story of stem cells and tumor microenvironment

Resetkova, E., Reis-Filho, J. S., Jain, R. K., Mehta, R., Thorat, M. A., Nakshatri, H. & Badve, S., Aug 1 2010, In : Breast Cancer Research and Treatment. 123, 1, p. 97-108 12 p.

Research output: Contribution to journalArticle

135 Scopus citations

Promoter context- and response element-dependent specificity of the transcriptional activation and modulating functions of retinoic acid receptors

Nagpal, S., Saunders, M., Kastner, P., Durand, B., Nakshatri, H. & Chambon, P., Sep 18 1992, In : Cell. 70, 6, p. 1007-1019 13 p.

Research output: Contribution to journalArticle

296 Scopus citations

Purification, cloning, and RXR identity of the HeLa cell factor with which RAR or TR heterodimerizes to bind target sequences efficiently

Leid, M., Kastner, P., Lyons, R., Nakshatri, H., Saunders, M., Zacharewski, T., Chen, J. Y., Staub, A., Garnier, J. M., Mader, S. & Chambon, P., Jan 24 1992, In : Cell. 68, 2, p. 377-395 19 p.

Research output: Contribution to journalArticle

982 Scopus citations

RareVar: A Framework for Detecting Low-Frequency Single-Nucleotide Variants

Hao, Y., Xuei, X., Li, L., Nakshatri, H., Edenberg, H. J. & Liu, Y., Jul 1 2017, In : Journal of Computational Biology. 24, 7, p. 637-646 10 p.

Research output: Contribution to journalArticle

3 Scopus citations

RARs and RXRs: Evidence for two autonomous transactivation functions (AF-1 and AF-2) and heterodimerization in vivo

Nagpal, S., Friant, S., Nakshatri, H. & Chambon, P., 1993, In : EMBO Journal. 12, 6, p. 2349-2360 12 p.

Research output: Contribution to journalArticle

Open Access
265 Scopus citations

Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3

Chen, A., Wang, L., Li, B. Y., Sherman, J., Ryu, J. E., Hamamura, K., Liu, Y., Nakshatri, H. & Yokota, H., Dec 1 2017, In : Scientific reports. 7, 1, 3459.

Research output: Contribution to journalArticle

11 Scopus citations

regSNPs-ASB: A Computational Framework for Identifying Allele-Specific Transcription Factor Binding From ATAC-seq Data

Xu, S., Feng, W., Lu, Z., Yu, C. Y., Shao, W., Nakshatri, H., Reiter, J. L., Gao, H., Chu, X., Wang, Y. & Liu, Y., Jul 29 2020, In : Frontiers in Bioengineering and Biotechnology. 8, 886.

Research output: Contribution to journalArticle

Open Access

Regulation of the c-jun gene in p210 BCR-ABL transformed cells corresponds with activity of JNK, the c-jun N-terminal kinase

Burgess, G. S., Williamson, E. A., Cripe, L. D., Litz-Jackson, S., Bhatt, J. A., Stanley, K., Stewart, M. J., Kraft, A. S., Nakshatri, H. & Boswell, H. S., Oct 1 1998, In : Blood. 92, 7, p. 2450-2460 11 p.

Research output: Contribution to journalArticle

Open Access
43 Scopus citations

Repression of GADD153/CHOP by NF-κB: A possible cellular defense against endoplasmic reticulum stress-induced cell death

Nozaki, S., Sledge, G. W. & Nakshatri, H., Apr 19 2001, In : Oncogene. 20, 17, p. 2178-2185 8 p.

Research output: Contribution to journalArticle

97 Scopus citations

Repression of transforming-growth-factor-β-mediated transcription by nuclear factor κB

Nagarajan, R. P., Chen, F., Li, W., Vig, E., Harrington, M. A., Nakshatri, H. & Chen, Y., Jun 15 2000, In : Biochemical Journal. 348, 3, p. 591-596 6 p.

Research output: Contribution to journalArticle

102 Scopus citations

Restoring chemotherapy and hormonetherapy sensitivity by parthenolide in a xenograft hormone refractory prostate cancer model

Shanmugam, R., Jayaprakasan, V., Gokmen-Polar, Y., Kelich, S., Miller, K. D., Yip-Schneider, M., Cheng, L., Bhat-Nakshatri, P., Sledge, G. W., Nakshatri, H., Zheng, Q. H., Miller, M. A., DeGrado, T., Hutchins, G. D. & Sweeney, C. J., Oct 1 2006, In : Prostate. 66, 14, p. 1498-1511 14 p.

Research output: Contribution to journalArticle

46 Scopus citations

Retinoic Acid Signal Transduction Pathways

LEID, MARK., KASTNER, PHILIPPE., DURAND, BÉATRICE., KRUST, ANDRÉE., LEROY, PIERRE., LYONS, RUTH., MENDELSOHN, CATHY., NAGPAL, SUNIL., NAKSHATRI, HARIKRISHNA., REIBEL, CORINNE., SAUNDERS, MICHAEL. & CHAMBON, PIERRE., Jun 1993, In : Annals of the New York Academy of Sciences. 684, 1, p. 19-34 16 p.

Research output: Contribution to journalArticle

46 Scopus citations

Retinoid receptors and binding proteins

Lohnes, D., Dierich, A., Ghyselinck, N., Kastner, P., Lampron, C., LeMeur, M., Lufkin, T., Mendelsohn, C., Nakshatri, H. & Chambon, P., 1992, In : Journal of cell science. 103, SUPPL. 16, p. 69-76 8 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Skeletal loading regulates breast cancer-associated osteolysis in a loading intensity-dependent fashion

Fan, Y., Jalali, A., Chen, A., Zhao, X., Liu, S., Teli, M., Guo, Y., Li, F., Li, J., Siegel, A., Yang, L., Liu, J., Na, S., Agarwal, M., Robling, A. G., Nakshatri, H., Li, B. Y. & Yokota, H., Dec 1 2020, In : Bone Research. 8, 1, 9.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

SLUG/SNAI2 and Tumor Necrosis Factor Generate Breast Cells With CD44+/CD24- Phenotype

Bhat-Nakshatri, P., Appaiah, H., Ballas, C., Pick-Franke, P., Goulet, R., Badve, S., Srour, E. F. & Nakshatri, H., Aug 6 2010, In : BMC Cancer. 10, 411.

Research output: Contribution to journalArticle

117 Scopus citations

Stage and tissue‐specific expression of the alcohol dehydrogenase 1 (Adh‐1) gene during mouse development

Vonesch, JL. L., Nakshatri, H., Philippe, M., Chambon, P. & Dollé, P., Mar 1994, In : Developmental Dynamics. 199, 3, p. 199-213 15 p.

Research output: Contribution to journalArticle

40 Scopus citations

Statistical modeling for sensitive detection of low-frequency single nucleotide variants

Hao, Y., Zhang, P., Xuei, X., Nakshatri, H., Edenberg, H. J., Li, L. & Liu, Y., Aug 22 2016, In : BMC genomics. 17, 514.

Research output: Contribution to journalArticle

3 Scopus citations

Striatin-3γ inhibits estrogen receptor activity by recruiting a protein phosphatase

Tan, B., Long, X., Nakshatri, H., Nephew, K. P. & Bigsby, R. M., May 2008, In : Journal of Molecular Endocrinology. 40, 5-6, p. 199-210 12 p.

Research output: Contribution to journalArticle

9 Scopus citations

Subcellular localization of activated AKT in estrogen receptor- and progesterone receptor-expressing breast cancers: Potential clinical implications

Badve, S., Collins, N. R., Bhat-Nakshatri, P., Turbin, D., Leung, S., Thorat, M., Dunn, S. E., Geistlinger, T. R., Carroll, J. S., Brown, M., Bose, S., Teitell, M. A. & Nakshatri, H., May 2010, In : American Journal of Pathology. 176, 5, p. 2139-2149 11 p.

Research output: Contribution to journalArticle

32 Scopus citations

Subunit association and DNA binding activity of the heterotrimeric transcription factor NF-Y is regulated by cellular redox

Nakshatri, H., Bhat-Nakshatri, P. & Currie, R. A., 1996, In : Journal of Biological Chemistry. 271, 46, p. 28784-28791 8 p.

Research output: Contribution to journalArticle

82 Scopus citations

Suppression of pancreatic tumor growth by combination chemotherapy with sulindac and LC-1 is associated with cyclin D1 inhibition in vivo

Yip-Schneider, M. T., Wu, H., Ralstin, M., Yiannoutsos, C., Crooks, P. A., Neelakantan, S., Noble, S., Nakshatri, H., Sweeney, C. J. & Schmidt, C. M., Jun 1 2007, In : Molecular cancer therapeutics. 6, 6, p. 1736-1744 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

TFAP2C expression in breast cancer: correlation with overall survival beyond 10 years of initial diagnosis

Perkins, S. M., Bales, C., Vladislav, T., Althouse, S., Miller, K. D., Sandusky, G., Badve, S. & Nakshatri, H., Aug 31 2015, In : Breast Cancer Research and Treatment. 152, 3, p. 519-531 13 p.

Research output: Contribution to journalArticle

16 Scopus citations
119 Scopus citations

The first 124 nucleotides of the E7 coding sequences of HPV16 can render the HPV11 genome transformation competent

Pater, M. M., Nakshatri, H., Kisaka, C. & Pater, A., Jan 1992, In : Virology. 186, 1, p. 348-351 4 p.

Research output: Contribution to journalArticle

5 Scopus citations

The macrophage inhibitory cytokine integrates AKT/PKB and MAP kinase signaling pathways in breast cancer cells

Wollmann, W., Goodman, M. L., Bhat-Nakshatri, P., Kishimoto, H., Goulet, R. J., Mehrotra, S., Morimiya, A., Badve, S. & Nakshatri, H., 2005, In : Carcinogenesis. 26, 5, p. 900-907 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

The mushroom Ganoderma lucidum suppresses breast-to-lung cancer metastasis through the inhibition of pro-invasive genes

Loganathan, J., Jiang, J., Smith, A., Jedinak, A., Thyagarajan-Sahu, A., Sandusky, G. E., Nakshatri, H. & Sliva, D., Jun 2014, In : International journal of oncology. 45, 6, p. 2009-2015 7 p.

Research output: Contribution to journalArticle

36 Scopus citations
30 Scopus citations

The p160 family coactivators regulate breast cancer cell proliferation and invasion through autocrine/paracrine activity of SDF-1α/CXCL12

Kishimoto, H., Wang, Z., Bhat-Nakshatri, P., Chang, D., Clarke, R. & Nakshatri, H., Oct 1 2005, In : Carcinogenesis. 26, 10, p. 1706-1715 10 p.

Research output: Contribution to journalArticle

55 Scopus citations
37 Scopus citations

The platelet-derived growth factor receptor α is destabilized by geldanamycins in cancer cells

Matei, D., Satpathy, M., Cao, L., Lai, Y. C., Nakshatri, H. & Donner, D. B., Jan 5 2007, In : Journal of Biological Chemistry. 282, 1, p. 445-453 9 p.

Research output: Contribution to journalArticle

54 Scopus citations

The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer

Sweeney, C. J., Mehrotra, S., Sadaria, M. R., Kumar, S., Shortle, N. H., Roman, Y., Sheridan, C., Campbell, R. A., Murry, D. J., Badve, S. & Nakshatri, H., Jun 2005, In : Molecular cancer therapeutics. 4, 6, p. 1004-1012 9 p.

Research output: Contribution to journalArticle

132 Scopus citations
75 Scopus citations

Transformation of interleukin-3-dependent cells without participation of Stat5/bcl-xL: Cooperation of akt with raf/erk leads to p65 nuclear factor kB-mediated antiapoptosis involving c-IAP2

Gelfanov, V. M., Burgess, G. S., Litz-Jackson, S., King, A. J., Marshall, M. S., Nakshatri, H. & Scott Boswell, H., Oct 15 2001, In : Blood. 98, 8, p. 2508-2517 10 p.

Research output: Contribution to journalArticle

36 Scopus citations

Tumour necrosis factor and PI3-kinase control oestrogen receptor alpha protein level and its transrepression function

Bhat-Nakshatri, P., Campbell, R. A., Patel, N. M., Newton, T. R., King, A. J., Marshall, M. S., Ali, S. & Nakshatri, H., Feb 23 2004, In : British Journal of Cancer. 90, 4, p. 853-859 7 p.

Research output: Contribution to journalArticle

26 Scopus citations

Ubiquitous and cell-type-specific protein interactions with human papillomavirus type 16 and type 18 enhancers

Nakshatri, H., Pater, M. M. & Pater, A., Sep 1990, In : Virology. 178, 1, p. 92-103 12 p.

Research output: Contribution to journalArticle

22 Scopus citations

Virtual screening targeting the urokinase receptor, biochemical and cell-based studies, synthesis, pharmacokinetic characterization, and effect on breast tumor metastasis

Wang, F., Li, J., Sinn, A. L., Knabe, W. E., Khanna, M., Jo, I., Silver, J. M., Oh, K., Li, L., Sandusky, G. E., Sledge, G. W., Nakshatri, H., Jones, D. R., Pollok, K. E. & Meroueh, S. O., Oct 27 2011, In : Journal of Medicinal Chemistry. 54, 20, p. 7193-7205 13 p.

Research output: Contribution to journalArticle

19 Scopus citations