Harm HogenEsch

  • 5467 Citations
  • 44 h-Index
1987 …2019

Research output per year

If you made any changes in Pure these will be visible here soon.

Publications

Filter
Article
2019

Corn-derived alpha-D-glucan nanoparticles as adjuvant for intramuscular and intranasal immunization in pigs

Dhakal, S., Lu, F., Ghimire, S., Renu, S., Lakshmanappa, Y. S., Hogshead, B. T., Ragland, D., HogenEsch, H. & Renukaradhya, G. J., Feb 2019, In : Nanomedicine: Nanotechnology, Biology, and Medicine. 16, p. 226-235 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Formulation of aluminum hydroxide adjuvant with TLR agonists poly(I:C) and CpG enhances the magnitude and avidity of the humoral immune response

Lu, F., Mosley, Y. Y. C., Carmichael, B., Brown, D. D. & HogenEsch, H., Mar 28 2019, In : Vaccine. 37, 14, p. 1945-1953 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Genetic variation in the magnitude and longevity of the igg subclass response to a diphtheria-tetanus-acellular pertussis (dtap) vaccine in mice

Mosley, Y. Y. C., Radder, J. E. & Esch, H. H., Dec 2019, In : Vaccines. 7, 4, 124.

Research output: Contribution to journalArticle

Open Access
2018

Mucosal immunity and protective efficacy of intranasal inactivated influenza vaccine is improved by chitosan nanoparticle delivery in pigs

Dhakal, S., Renu, S., Ghimire, S., Lakshmanappa, Y. S., Hogshead, B. T., Feliciano-Ruiz, N., Lu, F., HogenEsch, H., Krakowka, S., Lee, C. W. & Renukaradhya, G. J., May 2 2018, In : Frontiers in immunology. 9, MAY, 934.

Research output: Contribution to journalArticle

26 Scopus citations

Profiling of epidermal lipids in a mouse model of dermatitis: Identification of potential biomarkers

Franco, J., Ferreira, C., Paschoal Sobreira, T. J., Sundberg, J. P. & HogenEsch, H., Apr 2018, In : PloS one. 13, 4, e0196595.

Research output: Contribution to journalArticle

6 Scopus citations
2017

Alpha-D-glucan nanoparticulate adjuvant induces a transient inflammatory response at the injection site and targets antigen to migratory dendritic cells

Lu, F., Mosley, Y. Y. C., Rodriguez Rosales, R. J., Carmichael, B. E., Elesela, S., Yao, Y. & HogenEsch, H., Dec 1 2017, In : npj Vaccines. 2, 1, 7.

Research output: Contribution to journalArticle

12 Scopus citations
3 Scopus citations

Evaluation of the Potency, Neutralizing Antibody Response, and Stability of a Recombinant Fusion Protein Vaccine for Streptococcus pyogenes

Burlet, E., HogenEsch, H., Dunham, A. & Morefield, G., May 1 2017, In : AAPS Journal. 19, 3, p. 875-881 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Genome-wide association mapping of the antibody response to diphtheria, tetanus and acellular pertussis vaccine in mice

Mosley, Y. Y. C., Radder, J. E., Berndt, A. & HogenEsch, H., 2017, In : Journal of Infectious Diseases. 215, 3, p. 466-474 9 p.

Research output: Contribution to journalArticle

3 Scopus citations

Preclinical safety study of a recombinant Streptococcus pyogenes vaccine formulated with aluminum adjuvant

HogenEsch, H., Dunham, A., Burlet, E., Lu, F., Mosley, Y. Y. C. & Morefield, G., Feb 1 2017, In : Journal of Applied Toxicology. 37, 2, p. 222-230 9 p.

Research output: Contribution to journalArticle

7 Scopus citations

Selection of a suitable reference gene for quantitative gene expression in mouse lymph nodes after vaccination

Mosley, Y. Y. C. & Hogenesch, H., Dec 6 2017, In : BMC Research Notes. 10, 1, 689.

Research output: Contribution to journalArticle

3 Scopus citations
2016

Angiogenesis in the skin of SHARPIN-deficient mice with chronic proliferative dermatitis

HogenEsch, H., Sola, M., Stearns, T. M., Silva, K. A., Kennedy, V. E. & Sundberg, J. P., Dec 1 2016, In : Experimental and Molecular Pathology. 101, 3, p. 303-307 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Chronically elevated levels of short-chain fatty acids induce T Cell-mediated ureteritis and hydronephrosis

Park, J., Goergen, C. J., HogenEsch, H. & Kim, C. H., Mar 1 2016, In : Journal of Immunology. 196, 5, p. 2388-2400 13 p.

Research output: Contribution to journalArticle

53 Scopus citations

Dermal lymphatic dilation in a mouse model of alopecia areata

Sundberg, J. P., Pratt, C. H., Silva, K. A., Kennedy, V. E., Stearns, T. M., Sundberg, B. A., King, L. E. & HogenEsch, H., Apr 1 2016, In : Experimental and Molecular Pathology. 100, 2, p. 332-336 5 p.

Research output: Contribution to journalArticle

3 Scopus citations
2015

Dendrimer-like alpha-d-glucan nanoparticles activate dendritic cells and are effective vaccine adjuvants

Lu, F., Mencia, A., Bi, L., Taylor, A., Yao, Y. & HogenEsch, H., Apr 28 2015, In : Journal of Controlled Release. 204, p. 51-59 9 p., 7587.

Research output: Contribution to journalArticle

39 Scopus citations

The pathogenesis of chronic eosinophilic esophagitis in SHARPIN-deficient mice

Chien, S. J., Silva, K. A., Kennedy, V. E., HogenEsch, H. & Sundberg, J. P., Dec 1 2015, In : Experimental and Molecular Pathology. 99, 3, p. 460-467 8 p.

Research output: Contribution to journalArticle

4 Scopus citations
2014

Chronic proliferative dermatitis in Sharpin null mice: Development of an autoinflammatory disease in the absence of B and T lymphocytes and IL4/IL13 signaling

Potter, C. S., Wang, Z., Silva, K. A., Kennedy, V. E., Stearns, T. M., Burzenski, L., Shultz, L. D., HogenEsch, H. & Sundberg, J. P., Jan 21 2014, In : PloS one. 9, 1, e85666.

Research output: Contribution to journalArticle

39 Scopus citations

Development of a recombinant fusion protein vaccine formulation to protect against Streptococcus pyogenes

Morefield, G., Touhey, G., Lu, F., Dunham, A. & HogenEsch, H., Jan 1 2014, In : Vaccine. 32, 30, p. 3810-3815 6 p.

Research output: Contribution to journalArticle

14 Scopus citations

Notch-dependent repression of miR-155 in the bone marrow niche regulates hematopoiesis in an NF-κB-dependent manner

Wang, L., Zhang, H., Rodriguez, S., Cao, L., Parish, J., Mumaw, C., Zollman, A., Kamoka, M. M., Mu, J., Chen, D. Z., Srour, E. F., Chitteti, B. R., HogenEsch, H., Tu, X., Bellido, T. M., Boswell, H. S., Manshouri, T., Verstovsek, S., Yoder, M. C., Kapur, R. & 2 others, Cardoso, A. A. & Carlesso, N., Jul 3 2014, In : Cell Stem Cell. 15, 1, p. 51-65 15 p.

Research output: Contribution to journalArticle

106 Scopus citations

The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis

Chun, K. T., Li, B., Dobrota, E., Tate, C., Lee, J. H., Khan, S., Haneline, L., HogenEsch, H. & Skalnik, D. G., 2014, In : PLoS One. 9, 12, p. e113745

Research output: Contribution to journalArticle

The epigenetic regulator CXXC finger protein 1 is essential for murine hematopoiesis

Chun, K. T., Li, B., Dobrota, E., Tate, C., Lee, J. H., Khan, S., Haneline, L., HogenEsch, H. & Skalnik, D. G., Dec 3 2014, In : PLoS ONE. 9, 12, e113745.

Research output: Contribution to journalArticle

15 Scopus citations
2013

Control of antigen-binding to aluminum adjuvants and the immune response with a novel phosphonate linker

Lu, F., Boutselis, I., Borch, R. F. & HogenEsch, H., Sep 13 2013, In : Vaccine. 31, 40, p. 4362-4367 6 p.

Research output: Contribution to journalArticle

11 Scopus citations

Kinetics of the inflammatory response following intramuscular injection of aluminum adjuvant

Lu, F. & HogenEsch, H., Aug 20 2013, In : Vaccine. 31, 37, p. 3979-3986 8 p.

Research output: Contribution to journalArticle

44 Scopus citations

Loss of Function of the Mouse Sharpin Gene Results in Peyer's Patch Regression

Seymour, R., Shirley, B. J., HogenEsch, H., Shultz, L. D. & Sundberg, J. P., Feb 12 2013, In : PloS one. 8, 2, e55224.

Research output: Contribution to journalArticle

8 Scopus citations
2012

A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production

Puthiyaveetil, A. G., Heid, B., Reilly, C. M., HogenEsch, H. & Caudell, D. L., Aug 1 2012, In : Experimental Hematology. 40, 8, p. 622-633 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Challenges in pre-clinical testing of anti-cancer drugs in cell culture and in animal models

Hogenesch, H. & Nikitin, A. Y., Dec 10 2012, In : Journal of Controlled Release. 164, 2, p. 183-186 4 p.

Research output: Contribution to journalArticle

30 Scopus citations

Mechanism of immunopotentiation and safety of aluminum adjuvants

HogenEsch, H., Dec 1 2012, In : Frontiers in immunology. 3, JAN, Article 406.

Research output: Contribution to journalArticle

156 Scopus citations

SHARPIN is a key regulator of immune and inflammatory responses

Wang, Z., Potter, C. S., Sundberg, J. P. & Hogenesch, H., Oct 1 2012, In : Journal of Cellular and Molecular Medicine. 16, 10, p. 2271-2279 9 p.

Research output: Contribution to journalArticle

38 Scopus citations

SHARPIN is essential for cytokine production, NF-κB signaling, and induction of Th1 differentiation by dendritic cells

Wang, Z., Sokolovska, A., Seymour, R., Sundberg, J. P. & HogenEsch, H., Feb 14 2012, In : PloS one. 7, 2, e31809.

Research output: Contribution to journalArticle

27 Scopus citations

Training Mouse Pathologists: Ten Years of Workshops on the Pathology of Mouse Models of Human Disease

Sundberg, J. P., Hogenesch, H., Nikitin, A. Y., Treuting, P. M. & Ward, J. M., Jul 2012, In : Toxicologic Pathology. 40, 5, p. 823-825 3 p.

Research output: Contribution to journalArticle

4 Scopus citations

Training Pathologists in Mouse Pathology

Sundberg, J. P., Ward, J. M., HogenEsch, H., Nikitin, A. Y., Treuting, P. M., Macauley, J. B. & Schofield, P. N., Mar 1 2012, In : Veterinary Pathology. 49, 2, p. 393-397 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
2011

Effect of the strength of adsorption of HIV 1 SF162dV2gp140 to aluminum-containing adjuvants on the immune response

Hansen, B., Malyala, P., Singh, M., Sun, Y., Srivastava, I., Hogenesch, H. & Hem, S. L., Aug 2011, In : Journal of Pharmaceutical Sciences. 100, 8, p. 3245-3250 6 p.

Research output: Contribution to journalArticle

18 Scopus citations

Formulation of a killed whole cell pneumococcus vaccine - effect of aluminum adjuvants on the antibody and IL-17 response

HogenEsch, H., Dunham, A., Hansen, B., Anderson, K., Maisonneuve, J. F. & Hem, S. L., Jul 29 2011, In : Journal of Immune Based Therapies and Vaccines. 9, 5.

Research output: Contribution to journalArticle

14 Scopus citations
2010

Anti-IL5 decreases the number of eosinophils but not the severity of dermatitis in Sharpin-deficient mice

Renninger, M. L., Seymour, R. E., Whiteley, L. O., Sundberg, J. P. & HogenEsch, H., Mar 1 2010, In : Experimental Dermatology. 19, 3, p. 252-258 7 p.

Research output: Contribution to journalArticle

19 Scopus citations

Effect of Ageing on the Immune Response of Dogs to Vaccines

HogenEsch, H. & Thompson, S., Jan 1 2010, In : Journal of Comparative Pathology. 142, SUPPL. 1, p. S74-S77

Research output: Contribution to journalArticle

7 Scopus citations

Evaluation of innate immunity and vector toxicity following inoculation of bovine, porcine or human adenoviral vectors in a mouse model

Sharma, A., Bangari, D. S., Tandon, M., HogenEsch, H. & Mittal, S. K., Oct 1 2010, In : Virus Research. 153, 1, p. 134-142 9 p.

Research output: Contribution to journalArticle

15 Scopus citations
60 Scopus citations

Preformulation studies-The next advance in aluminum adjuvant-containing vaccines

Hem, S. L., HogenEsch, H., Middaugh, C. R. & Volkin, D. B., Jul 1 2010, In : Vaccine. 28, 31, p. 4868-4870 3 p.

Research output: Contribution to journalArticle

30 Scopus citations

Retinoic acid determines the precise tissue tropism of inflammatory Th17 cells in the intestine

Wang, C., Kang, S. G., HogenEsch, H., Love, P. E. & Kim, C. H., May 15 2010, In : Journal of Immunology. 184, 10, p. 5519-5526 8 p.

Research output: Contribution to journalArticle

70 Scopus citations

Vascular lesions in pigs experimentally infected with porcine circovirus type 2 serogroup B

Langohr, I. M., Stevenson, G. W., Nelson, E. A., Lenz, S. D., HogenEsch, H., Wei, H. & Pogranichniy, R. M., Jun 25 2010, In : Veterinary Pathology. 47, 1, p. 140-147 8 p.

Research output: Contribution to journalArticle

17 Scopus citations
2009

Comparative analysis of vector biodistribution, persistence and gene expression following intravenous delivery of bovine, porcine and human adenoviral vectors in a mouse model

Sharma, A., Bangari, D. S., Tandon, M., Pandey, A., HogenEsch, H. & Mittal, S. K., Mar 30 2009, In : Virology. 386, 1, p. 44-54 11 p.

Research output: Contribution to journalArticle

37 Scopus citations

Dysfunctional expansion of hematopoietic stem cells and block of myeloid differentiation in lethal sepsis

Rodriguez, S., Chora, A., Goumnerov, B., Mumaw, C., Goebel, W. S., Fernandez, L., Baydoun, H., HogenEsch, H., Dombkowski, D. M., Karlewicz, C. A., Rice, S., Rahme, L. G. & Carlesso, N., Nov 5 2009, In : Blood. 114, 19, p. 4064-4076 13 p.

Research output: Contribution to journalArticle

79 Scopus citations

Effect of the strength of adsorption of hepatitis B surface antigen to aluminum hydroxide adjuvant on the immune response

Hansen, B., Belfast, M., Soung, G., Song, L., Egan, P. M., Capen, R., HogenEsch, H., Mancinelli, R. & Hem, S. L., Feb 5 2009, In : Vaccine. 27, 6, p. 888-892 5 p.

Research output: Contribution to journalArticle

71 Scopus citations
2008

STAT4 isoforms differentially regulate Th1 cytokine production and the severity of inflammatory bowel disease

O'Malley, J. T., Eri, R. D., Stritesky, G. L., Mathur, A. N., Chang, H. C., HogenEsch, H., Srinivasan, M. & Kaplan, M. H., Oct 1 2008, In : Journal of Immunology. 181, 7, p. 5062-5070 9 p.

Research output: Contribution to journalArticle

Open Access
25 Scopus citations

Vascular-associated lymphoid tissue in swine (Sus scrofa)

Langohr, I. M., HogenEsch, H., Stevenson, G. W. & Sturek, M., Apr 1 2008, In : Comparative medicine. 58, 2, p. 168-173 6 p.

Research output: Contribution to journalArticle

7 Scopus citations
2007

Activation of dendritic cells and induction of CD4+ T cell differentiation by aluminum-containing adjuvants

Sokolovska, A., Hem, S. L. & HogenEsch, H., Jun 6 2007, In : Vaccine. 25, 23, p. 4575-4585 11 p.

Research output: Contribution to journalArticle

127 Scopus citations

Identification of a Chemokine Network That Recruits FoxP3+ Regulatory T Cells Into Chronically Inflamed Intestine

Kang, S. G., Piniecki, R. J., Hogenesch, H., Lim, H. W., Wiebke, E., Braun, S. E., Matsumoto, S. & Kim, C. H., Mar 2007, In : Gastroenterology. 132, 3, p. 966-981 16 p.

Research output: Contribution to journalArticle

48 Scopus citations

Potentiation of the immune response to non-adsorbed antigens by aluminum-containing adjuvants

Romero Méndez, I. Z., Shi, Y., HogenEsch, H. & Hem, S. L., Jan 15 2007, In : Vaccine. 25, 5, p. 825-833 9 p.

Research output: Contribution to journalArticle

92 Scopus citations

Relationship between the strength of antigen adsorption to an aluminum-containing adjuvant and the immune response

Hansen, B., Sokolovska, A., HogenEsch, H. & Hem, S. L., Sep 4 2007, In : Vaccine. 25, 36, p. 6618-6624 7 p.

Research output: Contribution to journalArticle

82 Scopus citations

Spontaneous mutations in the mouse Sharpin gene result in multiorgan inflammation, immune system dysregulation and dermatitis

Seymour, R. E., Hasham, M. G., Cox, G. A., Shultz, L. D., HogenEsch, H., Roopenian, D. C. & Sundberg, J. P., Jul 1 2007, In : Genes and Immunity. 8, 5, p. 416-421 6 p.

Research output: Contribution to journalArticle

136 Scopus citations