Howard Edenberg

  • 23743 Citations
  • 80 h-Index
1972 …2021
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Publications 1972 2019

2019

Allele-specific expression and high-throughput reporter assay reveal functional genetic variants associated with alcohol use disorders

Rao, X., Thapa, K. S., Chen, A. B., Lin, H., Gao, H., Reiter, J., Hargreaves, K. A., Ipe, J., Lai, D., Xuei, X., Wang, Y., Gu, H., Kapoor, M., Farris, S. P., Tischfield, J., Foroud, T., Goate, A. M., Skaar, T., Mayfield, R. D., Edenberg, H. & 1 others, Liu, Y., Jan 1 2019, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Alleles
Single Nucleotide Polymorphism
Alcohols
Genome-Wide Association Study
3' Untranslated Regions

Analysis of whole genome-transcriptomic organization in brain to identify genes associated with alcoholism

Kapoor, M., Wang, J. C., Farris, S. P., Liu, Y., McClintick, J., Gupta, I., Meyers, J. L., Bertelsen, S., Chao, M., Nurnberger, J., Tischfield, J., Harari, O., Zeran, L., Hesselbrock, V., Bauer, L., Raj, T., Porjesz, B., Agrawal, A., Foroud, T., Edenberg, H. & 2 others, Mayfield, R. D. & Goate, A., Dec 1 2019, In : Translational psychiatry. 9, 1, 89.

Research output: Contribution to journalArticle

Alcoholism
Genome
Alcohol Drinking
Brain
Genes

A Pilot Follow-Up Study of Older Alcohol-Dependent COGA Adults

Chan, G., Kramer, J. R., Schuckit, M. A., Hesselbrock, V., Bucholz, K. K., Edenberg, H., Acion, L., Langbehn, D., McCutcheon, V., Nurnberger, J., Hesselbrock, M., Porjesz, B., Bierut, L., Marenna, B. C., Cookman, A. & Kuperman, S., Jan 1 2019, In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Drinking
Alcohols
Alcohol Drinking
Alcoholism
Medical problems

Correction to: Psychiatric genetics and the structure of psychopathology (Molecular Psychiatry, (2019), 24, 3, (409-420), 10.1038/s41380-017-0010-4)

Smoller, J. W., Andreassen, O. A., Edenberg, H., Faraone, S. V., Glatt, S. J. & Kendler, K. S., Mar 1 2019, In : Molecular Psychiatry. 24, 3, 1 p.

Research output: Contribution to journalComment/debate

Open Access
Genetic Structures
Psychopathology
Psychiatry
1 Citation (Scopus)

Early Sexual Trauma Exposure and Neural Response Inhibition in Adolescence and Young Adults: Trajectories of Frontal Theta Oscillations During a Go/No-Go Task

Meyers, J., McCutcheon, V. V., Pandey, A. K., Kamarajan, C., Subbie, S., Chorlian, D., Salvatore, J., Pandey, G., Almasy, L., Anokhin, A., Bauer, L., Bender, A., Dick, D. M., Edenberg, H., Hesselbrock, V., Kramer, J., Kuperman, S., Agrawal, A., Bucholz, K. & Porjesz, B., Feb 1 2019, In : Journal of the American Academy of Child and Adolescent Psychiatry. 58, 2, p. 242-255.e2

Research output: Contribution to journalArticle

Neural Inhibition
Psychopathology
Young Adult
Alcohols
Wounds and Injuries

Efficient region-based test strategy uncovers genetic risk factors for functional outcome in bipolar disorder

Budde, M., Friedrichs, S., Alliey-Rodriguez, N., Ament, S., Badner, J. A., Berrettini, W. H., Bloss, C. S., Byerley, W., Cichon, S., Comes, A. L., Coryell, W., Craig, D. W., Degenhardt, F., Edenberg, H., Foroud, T., Forstner, A. J., Frank, J., Gershon, E. S., Goes, F. S., Greenwood, T. A. & 40 others, Guo, Y., Hipolito, M., Hood, L., Keating, B. J., Koller, D. L., Lawson, W. B., Liu, C., Mahon, P. B., McInnis, M. G., McMahon, F. J., Meier, S. M., Mühleisen, T. W., Murray, S. S., Nievergelt, C. M., Nurnberger, J., Nwulia, E. A., Potash, J. B., Quarless, D., Rice, J., Roach, J. C., Scheftner, W. A., Schork, N. J., Shekhtman, T., Shilling, P. D., Smith, E. N., Streit, F., Strohmaier, J., Szelinger, S., Treutlein, J., Witt, S. H., Zandi, P. P., Zhang, P., Zöllner, S., Bickeböller, H., Falkai, P. G., Kelsoe, J. R., Nöthen, M. M., Rietschel, M., Schulze, T. G. & Malzahn, D., Jan 1 2019, In : European Neuropsychopharmacology. 29, 1, p. 156-170 15 p.

Research output: Contribution to journalArticle

Open Access
Bipolar Disorder
Single Nucleotide Polymorphism
Haplotypes
Genes
Chromosomes, Human, Pair 15

Ethanol activates immune response in lymphoblastoid cells

McClintick, J., Tischfield, J. A., Deng, L., Kapoor, M., Xuei, X. & Edenberg, H., Sep 1 2019, In : Alcohol. 79, p. 81-91 11 p.

Research output: Contribution to journalArticle

Ethanol
Alcoholics
alcoholism
Genes
Gene expression

Evidence of causal effect of major depression on alcohol dependence: Findings from the psychiatric genomics consortium

Polimanti, R., Peterson, R. E., Ong, J. S., MacGregor, S., Edwards, A. C., Clarke, T. K., Frank, J., Gerring, Z., Gillespie, N. A., Lind, P. A., Maes, H. H., Martin, N. G., Mbarek, H., Medland, S. E., Streit, F., Agrawal, A., Edenberg, H., Kendler, K. S., Lewis, C. M., Sullivan, P. F. & 3 others, Wray, N. R., Gelernter, J. & Derks, E. M., Jan 1 2019, In : Psychological Medicine.

Research output: Contribution to journalArticle

Genomics
Alcoholism
Psychiatry
Depression
Alcohol Drinking
1 Citation (Scopus)

Exploring the relationship between polygenic risk for cannabis use, peer cannabis use and the longitudinal course of cannabis involvement

Johnson, E. C., Tillman, R., Aliev, F., Meyers, J. L., Salvatore, J. E., Anokhin, A. P., Dick, D. M., Edenberg, H., Kramer, J. R., Kuperman, S., McCutcheon, V. V., Nurnberger, J., Porjesz, B., Schuckit, M. A., Tischfield, J., Bucholz, K. K. & Agrawal, A., Jan 1 2019, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Cannabis
Odds Ratio
Genome-Wide Association Study

Fibroblast Growth Factor 23 Genotype and Cardiovascular Disease in Patients Undergoing Hemodialysis

Schwantes-An, T. H., Liu, S., Stedman, M., Decker, B., Wetherill, L., Edenberg, H., Vatta, M., Foroud, T., Chertow, G. M. & Moe, S., Jan 1 2019, (Accepted/In press) In : American Journal of Nephrology. p. 125-132 8 p.

Research output: Contribution to journalArticle

Renal Dialysis
Cardiovascular Diseases
Genotype
Heart Failure
Mortality
1 Citation (Scopus)

Genetics of Alcoholism

Edenberg, H., Gelernter, J. & Agrawal, A., Apr 1 2019, In : Current psychiatry reports. 21, 4, 26.

Research output: Contribution to journalReview article

Alcoholism
Alcohol Drinking
Alcohols
Population
Genes

Genome-wide association studies of alcohol dependence, DSM-IV criterion count and individual criteria

Lai, D., Wetherill, L., Bertelsen, S., Carey, C. E., Kamarajan, C., Kapoor, M., Meyers, J. L., Anokhin, A. P., Bennett, D. A., Bucholz, K. K., Chang, K. K., De Jager, P. L., Dick, D. M., Hesselbrock, V., Kramer, J., Kuperman, S., Nurnberger, J., Raj, T., Schuckit, M., Scott, D. M. & 9 others, Taylor, R. E., Tischfield, J., Hariri, A. R., Edenberg, H., Agrawal, A., Bogdan, R., Porjesz, B., Goate, A. M. & Foroud, T., Jul 1 2019, In : Genes, Brain and Behavior. 18, 6, e12579.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Diagnostic and Statistical Manual of Mental Disorders
Alcoholism
Drinking
Meta-Analysis

Genome-wide association studies of the self-rating of effects of ethanol (SRE)

Lai, D., Wetherill, L., Kapoor, M., Johnson, E. C., Schwandt, M., Ramchandani, V. A., Goldman, D., Joslyn, G., Rao, X., Liu, Y., Farris, S., Mayfield, R. D., Dick, D., Hesselbrock, V., Kramer, J., McCutcheon, V. V., Nurnberger, J., Tischfield, J., Goate, A., Edenberg, H. & 4 others, Porjesz, B., Agrawal, A., Foroud, T. & Schuckit, M., Jan 1 2019, In : Addiction Biology. e12800.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Alcoholism
Ethanol
Alcohols
Drinking
11 Citations (Scopus)

Genome-wide association study identifies 30 loci associated with bipolar disorder

eQTLGen Consortium, BIOS Consortium & the Bipolar Disorder Working Group of the Psychiatric Genomics Consortium, May 1 2019, In : Nature genetics. 51, 5, p. 793-803 11 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Bipolar Disorder
Genome
Neurotransmitter Transport Proteins
Endocannabinoids

Genome-wide association study identifies loci associated with liability to alcohol and drug dependence that is associated with variability in reward-related ventral striatum activity in African- and European-Americans

Wetherill, L., Lai, D., Johnson, E. C., Anokhin, A., Bauer, L., Bucholz, K. K., Dick, D. M., Hariri, A. R., Hesselbrock, V., Kamarajan, C., Kramer, J., Kuperman, S., Meyers, J. L., Nurnberger, J., Schuckit, M., Scott, D. M., Taylor, R. E., Tischfield, J., Porjesz, B., Goate, A. M. & 4 others, Edenberg, H., Foroud, T., Bogdan, R. & Agrawal, A., Jan 1 2019, In : Genes, Brain and Behavior. e12580.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Reward
African Americans
Alcoholism
Substance-Related Disorders
16 Citations (Scopus)

Genome-wide association study meta-analysis of the alcohol use disorders identification test (AUDIT) in two population-based cohorts

Sanchez-Roige, S., Palmer, A. A., Fontanillas, P., Elson, S. L., Adams, M. J., Howard, D. M., Edenberg, H., Davies, G., Crist, R. C., Deary, I. J., McIntosh, A. M., Clarke, T. K., Elson, L., Fontanillas, P., Furlotte, N. A., Hinds, D. A., Huber, K. E., Kleinman, A., Litterman, N. K., McCreight, J. C. & 13 others, McIntyre, M. H., Mountain, J. L., Noblin, E. S., Northover, C. A. M., Pitts, S. J., Sathirapongsasuti, J. F., Sazonova, O. V., Shelton, J. F., Shringarpure, S., Tian, C., Tung, J. Y., Vacic, V. & Wilson, C. H., Feb 1 2019, In : American Journal of Psychiatry. 176, 2, p. 107-118 12 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Meta-Analysis
Alcohols
Population
Alcohol Drinking

How Much Do You Drink on Your Heavy Drinking Day?

Edenberg, H., Sep 1 2019, In : Biological psychiatry. 86, 5, p. 330-332 3 p.

Research output: Contribution to journalArticle

Drinking

Positive and Negative Reinforcement Are Differentially Associated With Alcohol Consumption as a Function of Alcohol Dependence

Cho, S. B., Su, J., I-Chun Kuo, S., Bucholz, K. K., Chan, G., Edenberg, H., McCutcheon, V. V., Schuckit, M. A., Kramer, J. R. & Dick, D. M., Jan 1 2019, (Accepted/In press) In : Psychology of Addictive Behaviors.

Research output: Contribution to journalArticle

Alcohol Drinking
Alcoholism
Reinforcement (Psychology)
Substance-Related Disorders
Motivation

The Genetic Relationship Between Alcohol Consumption and Aspects of Problem Drinking in an Ascertained Sample

Johnson, E. C., St. Pierre, C. L., Meyers, J. L., Aliev, F., McCutcheon, V. V., Lai, D., Dick, D. M., Goate, A. M., Kramer, J., Kuperman, S., Nurnberger, J., Schuckit, M. A., Porjesz, B., Edenberg, H., Bucholz, K. K. & Agrawal, A., Jun 1 2019, In : Alcoholism: Clinical and Experimental Research. 43, 6, p. 1113-1125 13 p.

Research output: Contribution to journalArticle

Alcohol Drinking
Drinking
Alcohols
Alcoholism
Area Under Curve

Ting-Kai Li: In Memoriam

Hesselbrock, V. M., Hesselbrock, M., Pfefferbaum, A., Sullivan, E. V. & Edenberg, H., Feb 1 2019, In : Alcoholism, clinical and experimental research. 43, 2, p. 202-203 2 p.

Research output: Contribution to journalArticle

Tolnaftate
2018
3 Citations (Scopus)

A 22-Year Follow-Up (Range 16 to 23) of Original Subjects with Baseline Alcohol Use Disorders from the Collaborative Study on Genetics of Alcoholism

Schuckit, M. A., Smith, T. L., Danko, G., Kramer, J., Bucholz, K. K., Mccutcheon, V., Chan, G., Kuperman, S., Hesselbrock, V., Dick, D. M., Hesselbrock, M., Porjesz, B., Edenberg, H., Nureberger, J. I., Gregg, M., Schoen, L., Kawamura, M. & Mendoza, L. A., Jan 1 2018, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Alcoholism
Alcohols
Genetics
Drinking
Street Drugs

A Brief Critique of the TATES Procedure

Aliev, F., Salvatore, J. E., Agrawal, A., Almasy, L., Chan, G., Edenberg, H., Hesselbrock, V., Kuperman, S., Meyers, J. & Dick, D. M., Mar 1 2018, In : Behavior Genetics. 48, 2, p. 155-167 13 p.

Research output: Contribution to journalArticle

phenotype
inflation
Phenotype
Genome-Wide Association Study
Economic Inflation

A correction for sample overlap in genome-wide association studies in a polygenic pleiotropy-informed framework

Schizophrenia and Bipolar Disorder Working Groups of the Psychiatric Genomics Consortium, Jun 25 2018, In : BMC Genomics. 19, 1, 494.

Research output: Contribution to journalArticle

Genome-Wide Association Study
5 Citations (Scopus)

Alcohol Dehydrogenases, Aldehyde Dehydrogenases, and Alcohol Use Disorders: A Critical Review

Edenberg, H. & McClintick, J., Jan 1 2018, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Aldehyde Dehydrogenase
Alcohol Dehydrogenase
Genes
Alcohols
Metabolism

Detecting significant genotype–phenotype association rules in bipolar disorder: market research meets complex genetics

Breuer, R., Mattheisen, M., Frank, J., Krumm, B., Treutlein, J., Kassem, L., Strohmaier, J., Herms, S., Mühleisen, T. W., Degenhardt, F., Cichon, S., Nöthen, M. M., Karypis, G., Kelsoe, J., Greenwood, T., Nievergelt, C., Shilling, P., Shekhtman, T., Edenberg, H., Craig, D. & 32 others, Szelinger, S., Nurnberger, J., Gershon, E., Alliey-Rodriguez, N., Zandi, P., Goes, F., Schork, N., Smith, E., Koller, D., Zhang, P., Badner, J., Berrettini, W., Bloss, C., Byerley, W., Coryell, W., Foroud, T., Guo, Y., Hipolito, M., Keating, B., Lawson, W., Liu, C., Mahon, P., McInnis, M., Murray, S., Nwulia, E., Potash, J., Rice, J., Scheftner, W., Zöllner, S., McMahon, F. J., Rietschel, M. & Schulze, T. G., Dec 1 2018, In : International Journal of Bipolar Disorders. 6, 1, 24.

Research output: Contribution to journalArticle

Marketing
Bipolar Disorder
Genome-Wide Association Study
Genetic Research
Data Mining
5 Citations (Scopus)

Gene expression changes in the ventral hippocampus and medial prefrontal cortex of adolescent alcohol-preferring (P) rats following binge-like alcohol drinking

McClintick, J., McBride, W. J., Bell, R., Ding, Z. M., Liu, Y., Xuei, X. & Edenberg, H., May 1 2018, In : Alcohol. 68, p. 37-47 11 p.

Research output: Contribution to journalArticle

Prefrontal Cortex
Gene expression
Alcohol Drinking
Rats
Hippocampus
4 Citations (Scopus)

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Agrawal, A., Børglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R., Sullivan, P. F., Posthuma, D. & 1 others, Polderman, T. J. C., Jan 1 2018, (Accepted/In press) In : Psychological Medicine.

Research output: Contribution to journalArticle

Psychiatry
Obsessive-Compulsive Disorder
Attention Deficit Disorder with Hyperactivity
Alcoholism
Genotype
1 Citation (Scopus)

Genetic influences on eight psychiatric disorders based on family data of 4 408 646 full and half-siblings, and genetic data of 333 748 cases and controls - CORRIGENDUM

Pettersson, E., Lichtenstein, P., Larsson, H., Song, J., Agrawal, A., Børglum, A. D., Bulik, C. M., Daly, M. J., Davis, L. K., Demontis, D., Edenberg, H., Grove, J., Gelernter, J., Neale, B. M., Pardiñas, A. F., Stahl, E., Walters, J. T. R., Walters, R., Sullivan, P. F., Posthuma, D. & 1 others, Polderman, T. J. C., Jan 1 2018, (Accepted/In press) In : Psychological Medicine.

Research output: Contribution to journalArticle

Psychiatry
corrigendum
4 Citations (Scopus)

Genome-wide association study identifies a novel locus for cannabis dependence

Agrawal, A., Chou, Y. L., Carey, C. E., Baranger, D. A. A., Zhang, B., Sherva, R., Wetherill, L., Kapoor, M., Wang, J. C., Bertelsen, S., Anokhin, A. P., Hesselbrock, V., Kramer, J., Lynskey, M. T., Meyers, J. L., Nurnberger, J., Rice, J. P., Tischfield, J., Bierut, L. J., Degenhardt, L. & 16 others, Farrer, L. A., Gelernter, J., Hariri, A. R., Heath, A. C., Kranzler, H. R., Madden, P. A. F., Martin, N. G., Montgomery, G. W., Porjesz, B., Wang, T., Whitfield, J. B., Edenberg, H., Foroud, T., Goate, A. M., Bogdan, R. & Nelson, E. C., May 1 2018, In : Molecular Psychiatry. 23, 5, p. 1293-1302 10 p.

Research output: Contribution to journalArticle

Marijuana Abuse
Genome-Wide Association Study
Cannabis
Genome
Single Nucleotide Polymorphism
44 Citations (Scopus)

Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, Psychosis Endophenotypes International Consortium & Wellcome Trust Case-Control Consortium, Jun 14 2018, In : Cell. 173, 7, p. 1705-1715.e16

Research output: Contribution to journalArticle

Dissection
Bipolar Disorder
Schizophrenia
Genes
Potassium

Influence of Parental Alcohol Dependence Symptoms and Parenting on Adolescent Risky Drinking and Conduct Problems: A Family Systems Perspective

Su, J., Kuo, S. I. C., Aliev, F., Guy, M. C., Derlan, C. L., Edenberg, H., Nurnberger, J., Kramer, J. R., Bucholz, K. K., Salvatore, J. E. & Dick, D. M., Jan 1 2018, (Accepted/In press) In : Alcoholism: Clinical and Experimental Research.

Research output: Contribution to journalArticle

Parenting
Alcoholism
Alcohols
Fathers
Mothers
15 Citations (Scopus)

Psychiatric genetics and the structure of psychopathology

Smoller, J. W., Andreassen, O. A., Edenberg, H., Faraone, S. V., Glatt, S. J. & Kendler, K. S., Jan 9 2018, (Accepted/In press) In : Molecular Psychiatry. p. 1-12 12 p.

Research output: Contribution to journalArticle

Genetic Structures
Psychopathology
Psychiatry
Expert Testimony
Genomics
71 Citations (Scopus)

Psychiatric genomics: An update and an Agenda

Psychiatric Genomics Consortium Coordinating Committee, Jan 1 2018, In : American Journal of Psychiatry. 175, 1, p. 15-27 13 p.

Research output: Contribution to journalArticle

Genomics
Psychiatry
Precision Medicine
History
Therapeutics
21 Citations (Scopus)

Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

23andMe Research Team, Dec 1 2018, In : Nature Neuroscience. 21, 12, p. 1656-1669 14 p.

Research output: Contribution to journalArticle

Open Access
Genome-Wide Association Study
Alcoholism
Psychiatry
Genome
Drinking Behavior

Understanding Mechanisms of Genetic Risk for Adolescent Internalizing and Externalizing Problems: The Mediating Role of Parenting and Personality

Su, J., Kuo, S. I. C., Bucholz, K. K., Edenberg, H., Kramer, J. R., Schuckit, M. & Dick, D. M., Aug 1 2018, In : Twin Research and Human Genetics. 21, 4, p. 310-321 12 p.

Research output: Contribution to journalArticle

Parenting
Personality
Conduct Disorder
Major Depressive Disorder
Genetic Predisposition to Disease
2017
1 Citation (Scopus)

A GABRA2 polymorphism improves a model for prediction of drinking initiation

Kuperman, S., Chan, G., Kramer, J., Wetherill, L., Acion, L., Edenberg, H., Foroud, T., Nurnberger, J., Agrawal, A., Anokhin, A., Brooks, A., Hesselbrock, V., Hesselbrock, M., Schuckit, M., Tischfield, J. & Liu, X., Sep 1 2017, In : Alcohol. 63, p. 1-8 8 p.

Research output: Contribution to journalArticle

Polymorphism
Drinking
Genotype
Self Report
Single Nucleotide Polymorphism
1 Citation (Scopus)

Alcohol Dehydrogenases

Edenberg, H. & Bosron, W. F., Dec 15 2017, Biotransformation. Elsevier Inc., Vol. 10-15. p. 126-145 20 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Alcohol Dehydrogenase
Substrate Specificity
Enzymes
Alcohols
Pharmacogenetics
10 Citations (Scopus)

An endophenotype approach to the genetics of alcohol dependence: a genome wide association study of fast beta EEG in families of African ancestry

Meyers, J. L., Zhang, J., Wang, J. C., Su, J., Kuo, S. I., Kapoor, M., Wetherill, L., Bertelsen, S., Lai, D., Salvatore, J. E., Kamarajan, C., Chorlian, D., Agrawal, A., Almasy, L., Bauer, L., Bucholz, K. K., Chan, G., Hesselbrock, V., Koganti, L., Kramer, J. & 11 others, Kuperman, S., Manz, N., Pandey, A., Seay, M., Scott, D., Taylor, R. E., Dick, D. M., Edenberg, H., Goate, A., Foroud, T. & Porjesz, B., Jan 10 2017, (Accepted/In press) In : Molecular Psychiatry.

Research output: Contribution to journalArticle

Endophenotypes
Genome-Wide Association Study
Alcoholism
Electroencephalography
Single Nucleotide Polymorphism
1 Citation (Scopus)

Associations of parental alcohol use disorders and parental separation with offspring initiation of alcohol, cigarette and cannabis use and sexual debut in high-risk families

Mccutcheon, V. V., Agrawal, A., Kuo, S. I. C., Su, J., Dick, D. M., Meyers, J. L., Edenberg, H., Nurnberger, J., Kramer, J. R., Kuperman, S., Schuckit, M. A., Hesselbrock, V. M., Brooks, A., Porjesz, B. & Bucholz, K. K., 2017, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Cannabis
Tobacco Products
Alcohols
Parents
Tobacco Use

Characterizing the roles of long non-coding RNA in rat alcohol preference

Zhou, A., Wang, Y., Liu, Y., Feng, W. & Edenberg, H., Jan 17 2017, Proceedings - 2016 IEEE International Conference on Bioinformatics and Biomedicine, BIBM 2016. Institute of Electrical and Electronics Engineers Inc., p. 167-173 7 p. 7822513

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Long Noncoding RNA
Rats
Alcohols
Gene expression
Genes
10 Citations (Scopus)

Comparison of Parent, Peer, Psychiatric, and Cannabis Use Influences Across Stages of Offspring Alcohol Involvement: Evidence from the COGA Prospective Study

Bucholz, K. K., McCutcheon, V. V., Agrawal, A., Dick, D. M., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J., Salvatore, J. E., Schuckit, M. A., Bierut, L. J., Foroud, T., Chan, G., Hesselbrock, M., Meyers, J. L., Edenberg, H. & Porjesz, B., Feb 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 2, p. 359-368 10 p.

Research output: Contribution to journalArticle

Cannabis
Psychiatry
Alcohols
Prospective Studies
Wounds and Injuries
4 Citations (Scopus)

Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands

Mccutcheon, V. V., Schuckit, M. A., Kramer, J. R., Chan, G., Edenberg, H., Smith, T. L., Bender, A. K., Hesselbrock, V., Hesselbrock, M. & Bucholz, K. K., 2017, (Accepted/In press) In : Addiction.

Research output: Contribution to journalArticle

Alcohols
Alcohol-Related Disorders
Alcohol Drinking
Self Report
Alcoholism
19 Citations (Scopus)

Genetic Overlap Between Attention-Deficit/Hyperactivity Disorder and Bipolar Disorder: Evidence From Genome-wide Association Study Meta-analysis

PGC ADHD Working Group & PGC Bipolar Disorder Working Group, Nov 1 2017, In : Biological Psychiatry. 82, 9, p. 634-641 8 p.

Research output: Contribution to journalArticle

Genome-Wide Association Study
Attention Deficit Disorder with Hyperactivity
Bipolar Disorder
Meta-Analysis
Nucleotides
14 Citations (Scopus)

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

Collaborative Study of the Genetics of Alcoholism Consortium & the German Study of the Genetics of Addiction Consortium, May 1 2017, In : Alcoholism: Clinical and Experimental Research. 41, 5, p. 911-928 18 p.

Research output: Contribution to journalArticle

Alcoholism
Ethanol
Genes
Alcohols
Long Noncoding RNA
27 Citations (Scopus)

Genome-wide association study of borderline personality disorder reveals genetic overlap with bipolar disorder, major depression and schizophrenia

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bipolar Disorders Working Group of the Psychiatric Genomics Consortium & Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Jun 20 2017, In : Translational Psychiatry. 7, 6, p. e1155

Research output: Contribution to journalArticle

Borderline Personality Disorder
Genome-Wide Association Study
Bipolar Disorder
Schizophrenia
Depression
14 Citations (Scopus)

Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

Andersen, A. M., Pietrzak, R. H., Kranzler, H. R., Ma, L., Zhou, H., Liu, X., Kramer, J., Kuperman, S., Edenberg, H., Nurnberger, J., Rice, J. P., Tischfield, J. A., Goate, A., Foroud, T., Meyers, J. L., Porjesz, B., Dick, D. M., Hesselbrock, V., Boerwinkle, E., Southwick, S. M. & 6 others, Krystal, J. H., Weissman, M. M., Levinson, D. F., Potash, J. B., Gelernter, J. & Han, S., Nov 1 2017, In : JAMA Psychiatry. 74, 11, p. 1153-1160 8 p.

Research output: Contribution to journalArticle

Major Depressive Disorder
Alcoholism
Genome-Wide Association Study
Veterans
Meta-Analysis
3 Citations (Scopus)

RareVar: A Framework for Detecting Low-Frequency Single-Nucleotide Variants

Hao, Y., Xuei, X., Li, L., Nakshatri, H., Edenberg, H. & Liu, Y., Jul 1 2017, In : Journal of Computational Biology. 24, 7, p. 637-646 10 p.

Research output: Contribution to journalArticle

Nucleotides
Sequencing
Low Frequency
Tumors
Tumor
4 Citations (Scopus)

Reciprocal relationships between substance use and disorders and suicidal ideation and suicide attempts in the Collaborative Study of the Genetics of Alcoholism

Agrawal, A., Tillman, R., Grucza, R. A., Nelson, E. C., McCutcheon, V. V., Few, L., Conner, K. R., Lynskey, M. T., Dick, D. M., Edenberg, H., Hesselbrock, V. M., Kramer, J. R., Kuperman, S., Nurnberger, J., Schuckit, M. A., Porjesz, B. & Bucholz, K. K., Apr 15 2017, In : Journal of Affective Disorders. 213, p. 96-104 9 p.

Research output: Contribution to journalArticle

Suicidal Ideation
Suicide
Alcoholism
Substance-Related Disorders
Marijuana Abuse
1 Citation (Scopus)

Substance use disorders in adolescent and young adult relatives of probands with bipolar disorder: What drives the increased risk?

Hulvershorn, L., King, J., Monahan, P., Wilcox, H. C., Mitchell, P. B., Fullerton, J. M., Edenberg, H., Roberts, G. M. P., Kamali, M., Glowinski, A. L., Ghaziuddin, N., McInnis, M., Iyer-Eimerbrink, P. A. & Nurnberger, J., Oct 1 2017, In : Comprehensive Psychiatry. 78, p. 130-139 10 p.

Research output: Contribution to journalArticle

Bipolar Disorder
Substance-Related Disorders
Young Adult
Drive
Diagnostic and Statistical Manual of Mental Disorders
9 Citations (Scopus)
Drinking
Trajectories
Alcohols
Genes
Alcoholism