Howard Masuoka

  • 1228 Citations
  • 13 h-Index
20022017
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Publications 2002 2017

  • 1228 Citations
  • 13 h-Index
  • 21 Article
  • 1 Chapter
2017
8 Citations (Scopus)

Function of inhibitor of Bruton's tyrosine kinase isoform α(IBTKα) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response

Willy, J. A., Young, S. K., Mosley, A., Gawrieh, S., Stevens, J. L., Masuoka, H. & Wek, R., Aug 25 2017, In : Journal of Biological Chemistry. 292, 34, p. 14050-14065 16 p.

Research output: Contribution to journalArticle

Unfolded Protein Response
Autophagy
Protein Isoforms
Proteins
Endoplasmic Reticulum
2 Citations (Scopus)
HMGB1 Protein
fatty liver
Liver
pioglitazone
Serum
2016
Open Access
Lymphoma, Large B-Cell, Diffuse
Stomach Ulcer
Weight Loss
Stomach
Cells
2015
50 Citations (Scopus)

CHOP links endoplasmic reticulum stress to NF-κB activation in the pathogenesis of nonalcoholic steatohepatitis

Willy, J. A., Young, S. K., Stevens, J. L., Masuoka, H. & Wek, R., Jun 15 2015, In : Molecular Biology of the Cell. 26, 12, p. 2190-2204 15 p.

Research output: Contribution to journalArticle

Endoplasmic Reticulum Stress
Hepatocytes
Unfolded Protein Response
Nonesterified Fatty Acids
Inflammation
Chemical and Drug Induced Liver Injury
Skin
Rivaroxaban
9 Citations (Scopus)

Individuals with Primary Sclerosing Cholangitis Have Elevated Levels of Biomarkers for Apoptosis but Not Necrosis

Masuoka, H., Vuppalanchi, R., Deppe, R., Bybee, P., Comerford, M., Liangpunsakul, S., Ghabril, M. & Chalasani, N., Dec 1 2015, In : Digestive Diseases and Sciences. 60, 12, p. 3642-3646 5 p.

Research output: Contribution to journalArticle

Sclerosing Cholangitis
Necrosis
Biomarkers
Apoptosis
HMGB1 Protein
13 Citations (Scopus)

Liver injury and fibrosis induced by dietary challenge in the ossabaw miniature swine

Liang, T., Alloosh, M., Bell, L. N., Fullenkamp, A., Saxena, R., Van Alstine, W., Bybee, P., Werling, K., Sturek, M., Chalasani, N. & Masuoka, H., May 15 2015, In : PLoS One. 10, 5, 0124173.

Research output: Contribution to journalArticle

Miniature Swine
miniature swine
Nutrition
fibrosis
Liver Cirrhosis
20 Citations (Scopus)

Severe Drug-Induced Skin and Liver Injury from Rivaroxaban

Barrett, P., Vuppalanchi, R., Masuoka, H. & Chalasani, N., Jun 5 2015, In : Digestive Diseases and Sciences. 60, 6, p. 1856-1858 3 p.

Research output: Contribution to journalArticle

Morpholines
Drug Eruptions
Chemical and Drug Induced Liver Injury
Thiophenes
Drug-Related Side Effects and Adverse Reactions
2014
40 Citations (Scopus)

Relationship Between Changes in Serum Levels of Keratin 18 and Changes in Liver Histology in Children and Adults With Nonalcoholic Fatty Liver Disease

Vuppalanchi, R., Jain, A. K., Deppe, R., Yates, K., Comerford, M., Masuoka, H., Neuschwander-Tetri, B. A., Loomba, R., Brunt, E. M., Kleiner, D. E., Molleston, J., Schwimmer, J. B., Lavine, J. E., Tonascia, J. & Chalasani, N., Dec 1 2014, In : Clinical Gastroenterology and Hepatology. 12, 12, p. 2121-2130 10 p.

Research output: Contribution to journalArticle

Keratin-18
Histology
Liver
Serum
Confidence Intervals
2013
137 Citations (Scopus)
Liver
Weight Loss
Medical problems
Type 2 Diabetes Mellitus
Thiazolidinediones
2012

Cholangiocarcinoma

Masuoka, H., Gores, G. J. & Rosen, C. B., Mar 28 2012, Medical Care of the Liver Transplant Patient: 4th Edition. Wiley-Blackwell, p. 133-144 12 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Cholangiocarcinoma
Klatskin Tumor
Neoadjuvant Therapy
Sclerosing Cholangitis
Transplants
36 Citations (Scopus)

Lumican, an extracellular matrix proteoglycan, is a novel requisite for hepatic fibrosis

Krishnan, A., Li, X., Kao, W. Y., Viker, K., Butters, K., Masuoka, H., Knudsen, B., Gores, G. & Charlton, M., Dec 2012, In : Laboratory Investigation. 92, 12, p. 1712-1725 14 p.

Research output: Contribution to journalArticle

Proteoglycans
Extracellular Matrix
Fibrosis
Liver
Palmitic Acid
2011
56 Citations (Scopus)

A role for miR-296 in the regulation of lipoapoptosis by targeting PUMA

Cazanave, S. C., Mott, J. L., Elmi, N. A., Bronk, S. F., Masuoka, H., Charlton, M. R. & Gores, G. J., Aug 2011, In : Journal of Lipid Research. 52, 8, p. 1517-1525 9 p.

Research output: Contribution to journalArticle

Liver
Palmitates
3' Untranslated Regions
MicroRNAs
Nonesterified Fatty Acids
3 Citations (Scopus)

Liver Transplantation for Hepatocellular Carcinoma: Expanding Frontiers and Building Bridges

Masuoka, H. & Rosen, C. B., May 2011, In : Clinics in Liver Disease. 15, 2, p. 385-393 9 p.

Research output: Contribution to journalArticle

Liver Transplantation
Hepatocellular Carcinoma
Transplantation
Therapeutics
Patient Selection
11 Citations (Scopus)

Transplantation for Cholangiocarcinoma

Masuoka, H. & Rosen, C. B., Nov 2011, In : Clinics in Liver Disease. 15, 4, p. 699-715 17 p.

Research output: Contribution to journalArticle

Cholangiocarcinoma
Sclerosing Cholangitis
Neoadjuvant Therapy
Transplantation
Liver Transplantation
2010
1 Citation (Scopus)

Clinical relevance of apoptotic regulatory proteins in colorectal cancers

Masuoka, H. & Sinicrope, F. A., Jul 2010, In : Current Colorectal Cancer Reports. 6, 3, p. 111-117 7 p.

Research output: Contribution to journalArticle

Colorectal Neoplasms
Death Domain Receptors
Neoplasms
Proteins
Apoptosis
2009
22 Citations (Scopus)

Caspase Inhibitors for the Treatment of Hepatitis C

Masuoka, H., Guicciardi, M. E. & Gores, G. J., Aug 2009, In : Clinics in Liver Disease. 13, 3, p. 467-475 9 p.

Research output: Contribution to journalArticle

Caspase Inhibitors
Hepatitis C
Apoptosis
Hepatocytes
Liver
32 Citations (Scopus)

Mcl-1 degradation during hepatocyte lipoapoptosis

Masuoka, H., Mott, J., Bronk, S. F., Werneburg, N. W., Akazawa, Y., Kaufmann, S. H. & Gores, G. J., Oct 30 2009, In : Journal of Biological Chemistry. 284, 44, p. 30039-30048 10 p.

Research output: Contribution to journalArticle

Palmitates
Protein Kinase C
Hepatocytes
Degradation
Phosphorylation
13 Citations (Scopus)

Methamphetamine colitis: A rare case of ischemic colitis in a young patient

Holubar, S. D., Hassinger, J. P., Dozois, E. J. & Masuoka, H., Aug 2009, In : Archives of Surgery. 144, 8, p. 780-782 3 p.

Research output: Contribution to journalArticle

Ischemic Colitis
Methamphetamine
Colitis
Signs and Symptoms
2008
68 Citations (Scopus)

TRAIL mediates liver injury by the innate immune system in the bile duct-ligated mouse

Kahraman, A., Barreyro, F. J., Bronk, S. F., Werneburg, N. W., Mott, J. L., Akazawa, Y., Masuoka, H., Howe, C. L. & Gores, G. J., Apr 2008, In : Hepatology. 47, 4, p. 1317-1330 14 p.

Research output: Contribution to journalArticle

Bile Ducts
Immune System
Liver
Wounds and Injuries
Wild Animals
2004
552 Citations (Scopus)

ATF4 is a substrate of RSK2 and an essential regulator of osteoblast biology: Implication for Coffin-Lowry syndrome

Yang, X., Matsuda, K., Bialek, P., Jacquot, S., Masuoka, H., Schinke, T., Li, L., Brancorsini, S., Sassone-Corsi, P., Townes, T. M., Hanauer, A. & Karsenty, G., Apr 30 2004, In : Cell. 117, 3, p. 387-398 12 p.

Research output: Contribution to journalArticle

Coffin-Lowry Syndrome
Osteoblasts
Substrates
Bone
Activating Transcription Factor 4
2002
155 Citations (Scopus)

Targeted disruption of the activating transcription factor 4 gene results in severe fetal anemia in mice

Masuoka, H. & Townes, T. M., Feb 1 2002, In : Blood. 99, 3, p. 736-745 10 p.

Research output: Contribution to journalArticle

Activating Transcription Factor 4
Liver
Anemia
Genes
Hematopoiesis