James Fletcher

  • 4416 Citations
  • 22 h-Index
1969 …2019
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Publications 1969 2019

  • 4416 Citations
  • 22 h-Index
  • 104 Article
  • 3 Chapter
  • 2 Conference contribution
2019

[68Ga]Ga-P16-093 as a PSMA-Targeted PET Radiopharmaceutical for Detection of Cancer: Initial Evaluation and Comparison with [68Ga]Ga-PSMA-11 in Prostate Cancer Patients Presenting with Biochemical Recurrence

Green, M., Hutchins, G., Bahler, C. D., Tann, M., Mathias, C. J., Territo, W., Sims, J., Polson, H., Alexoff, D., Eckelman, W. C., Kung, H. F. & Fletcher, J., Jan 1 2019, (Accepted/In press) In : Molecular Imaging and Biology.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Positron-Emission Tomography
Prostatic Neoplasms
Recurrence
Radiometry
2017
6 Citations (Scopus)

Estimation of radiation dosimetry for 68Ga-HBED-CC (PSMA-11) in patients with suspected recurrence of prostate cancer

Green, M., Eitel, J. A., Fletcher, J., Mathias, C. J., Tann, M. A., Territo, W., Polson, H., Hutchins, G., Gardner, T. & Koch, M., Mar 1 2017, In : Nuclear Medicine and Biology. 46, p. 32-35 4 p.

Research output: Contribution to journalArticle

Radiometry
Prostatic Neoplasms
Recurrence
Pelvis
Injections
7 Citations (Scopus)
Smell
Amyloid
Positron-Emission Tomography
Atrophy
Alzheimer Disease
2016
3 Citations (Scopus)

Experience in production of 68Ga-DOTA-NOC for clinical use under an Expanded Access IND

Green, M., Mathias, C. J. & Fletcher, J., Oct 1 2016, In : Applied Radiation and Isotopes. 116, p. 63-68 6 p.

Research output: Contribution to journalArticle

generators
expiration
dosage
elution
synthesis
2015
7 Citations (Scopus)

Evaluation of <sup>11</sup>C-Acetate and <sup>18</sup> F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma

Territo, P., Maluccio, M., Riley, A. A., McCarthy, B. P., Fletcher, J., Tann, M., Saxena, R. & Skill, N., May 16 2015, In : BMC Medical Imaging. 15, 1, 15.

Research output: Contribution to journalArticle

MDR Genes
Hepatocellular Carcinoma
Multiple Drug Resistance
Liver
carbon-11 acetate
4 Citations (Scopus)
Renal Cell Carcinoma
Perfusion
Water
Perfusion Imaging
Neoplasms
2014
10 Citations (Scopus)
Yttrium
Microspheres
Positron-Emission Tomography
Hepatocellular Carcinoma
Liver
2 Citations (Scopus)
kits
elution
Perfusion Imaging
delivery
Radiopharmaceuticals
13 Citations (Scopus)

The impact of image reconstruction bias on PET/CT 90Y dosimetry after radioembolization

Tapp, K. N., Lea, W. B., Johnson, M. S., Tann, M., Fletcher, J. & Hutchins, G., Sep 1 2014, In : Journal of Nuclear Medicine. 55, 9, p. 1452-1458 7 p.

Research output: Contribution to journalArticle

Computer-Assisted Image Processing
Photons
Electrons
Radiometry
Neoplasms
2013
5 Citations (Scopus)

PARP1 gene variation and microglial activity on [11C]PBR28 PET in older adults at risk for Alzheimer's disease

Kim, S., Nho, K., Risacher, S. L., Inlow, M., Swaminathan, S., Yoder, K., Shen, L., West, J. D., McDonald, B., Tallman, E. F., Hutchins, G., Fletcher, J., Farlow, M., Ghetti, B. & Saykin, A., 2013, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). Vol. 8159 LNCS. p. 150-158 9 p. (Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics); vol. 8159 LNCS).

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Administrative data processing
Positron Emission Tomography
Positron emission tomography
Alzheimer's Disease
Genes
2012
90 Citations (Scopus)

Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: A phase 2 trial

Robertson, K., Nalepa, G., Yang, F. C., Bowers, D. C., Ho, C., Hutchins, G., Croop, J., Vik, T., Denne, S., Parada, L. F., Hingtgen, C. M., Walsh, L., Yu, M., Pradhan, K., Edwards-Brown, M. K., Cohen, M. D., Fletcher, J., Travers, J., Staser, K. W., Lee, M. W. & 5 others, Sherman, M. R., Davis, C. J., Miller, L. C., Ingram, D. & Clapp, D., Dec 2012, In : The Lancet Oncology. 13, 12, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

Plexiform Neurofibroma
Neurofibromatosis 1
Imatinib Mesylate
Neoplasms
Chemoradiotherapy
2011
1 Citation (Scopus)

Probability and the principles of diagnostic certainty in medical imaging

Kymes, S. & Fletcher, J., 2011, Clinical PET-CT in Radiology: Integrated Imaging in Oncology. Springer New York, p. 131-145 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Evidence-Based Practice
Diagnostic Imaging
Patient Preference
Risk Management
Practice Guidelines
2010
71 Citations (Scopus)

A Pilot Trial of Serial 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients With Medically Inoperable Stage I Non-Small-Cell Lung Cancer Treated With Hypofractionated Stereotactic Body Radiotherapy

Henderson, M. A., Hoopes, D. J., Fletcher, J., Lin, P. F., Tann, M., Yiannoutsos, C., Williams, M. D., Fakiris, A. J., McGarry, R. C. & Timmerman, R. D., Mar 1 2010, In : International Journal of Radiation Oncology Biology Physics. 76, 3, p. 789-795 7 p.

Research output: Contribution to journalArticle

Radiosurgery
Fluorodeoxyglucose F18
Non-Small Cell Lung Carcinoma
Positron-Emission Tomography
lungs
211 Citations (Scopus)
Emission-Computed Tomography
Glucose
Fluorodeoxyglucose F18
Practice Guidelines
Neoplasms
2009
2 Citations (Scopus)

Reply: PET for the evaluation of solitary pulmonary nodules

Fletcher, J., Feb 1 2009, In : Journal of Nuclear Medicine. 50, 2, p. 326-327 2 p.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
2008
102 Citations (Scopus)

A comparison of the diagnostic accuracy of 18F-FDG PET and CT in the characterization of solitary pulmonary nodules

Fletcher, J., Kymes, S. M., Gould, M., Alazraki, N., Coleman, R. E., Lowe, V. J., Marn, C., Segall, G., Thet, L. A. & Lee, K., Feb 1 2008, In : Journal of Nuclear Medicine. 49, 2, p. 179-185 7 p.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
Fluorodeoxyglucose F18
Confidence Intervals
Veterans
Radiography
15 Citations (Scopus)

Can FDG-PET be used to predict growth of stage I lung cancer?

Tann, M., Sandrasegaran, K., Winer-Muram, H. T., Jennings, S. G., Welling, M. E. & Fletcher, J., Aug 2008, In : Clinical Radiology. 63, 8, p. 856-863 8 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Lung Neoplasms
Glucose
Growth
Tomography
658 Citations (Scopus)

Recommendations on the use of 18F-FDG PET in oncology

Fletcher, J., Djulbegovic, B., Soares, H. P., Siegel, B. A., Lowe, V. J., Lyman, G. H., Coleman, R. E., Wahl, R., Paschold, J. C., Avril, N., Einhorn, L., Suh, W. W., Samson, D., Delbeke, D., Gorman, M. & Shields, A. F., Mar 1 2008, In : Journal of Nuclear Medicine. 49, 3, p. 480-508 29 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Head and Neck Neoplasms
Unknown Primary Neoplasms
Lymphoma
Lung Neoplasms
2007
355 Citations (Scopus)

Evaluation of patients with pulmonary nodules: When is it lung cancer? ACCP evidence-based clinical practice guidelines (2nd edition)

Gould, M. K., Fletcher, J., Iannettoni, M. D., Lynch, W. R., Midthun, D. E., Naidich, D. P. & Ost, D. E., Sep 2007, In : Chest. 132, 3 SUPPL.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
Patient Preference
Evidence-Based Practice
Practice Guidelines
Lung Neoplasms
129 Citations (Scopus)

FDG-PET and stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer

Hoopes, D. J., Tann, M., Fletcher, J., Forquer, J. A., Lin, P. F., Lo, S. S., Timmerman, R. D. & McGarry, R. C., May 2007, In : Lung Cancer. 56, 2, p. 229-234 6 p.

Research output: Contribution to journalArticle

Radiosurgery
Non-Small Cell Lung Carcinoma
Positron-Emission Tomography
Recurrence
Survival
2006
4 Citations (Scopus)
Solitary Pulmonary Nodule
Positron-Emission Tomography
Smoking
Routine Diagnostic Tests
Health Policy

A three-part study to investigate the incidence and potential etiologies of tadalafil-associated back pain or myalgia

Seftel, A. D., Farber, J., Fletcher, J., Deeley, M. C., Elion-Mboussa, A., Hoover, A., Yu, A. & Fredlund, P., Apr 2006, In : Journal of Urology. 175, 4, p. 1450 1 p.

Research output: Contribution to journalArticle

88 Citations (Scopus)

Cerebral blood flow changes during vagus nerve stimulation for depression

Conway, C. R., Sheline, Y. I., Chibnall, J. T., George, M. S., Fletcher, J. & Mintun, M. A., Mar 31 2006, In : Psychiatry Research - Neuroimaging. 146, 2, p. 179-184 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Vagus Nerve Stimulation
Depression
Regional Blood Flow
Treatment-Resistant Depressive Disorder
929 Citations (Scopus)

Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer

Timmerman, R., McGarry, R., Yiannoutsos, C., Papiez, L., Tudor, K., DeLuca, J., Ewing, M., Abdulrahman, R., DesRosiers, C., Williams, M. & Fletcher, J., Oct 20 2006, In : Journal of Clinical Oncology. 24, 30, p. 4833-4839 7 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Radiotherapy
Neoplasms
Non-Small Cell Lung Carcinoma
Therapeutics

Preface

Fletcher, J., Oct 2006, In : PET Clinics. 1, 4

Research output: Contribution to journalArticle

2005
8 Citations (Scopus)

A three-part study to investigate the incidence and potential etiologies of tadalafil-associated back pain or myalgia

Seftel, A. D., Farber, J., Fletcher, J., Deeley, M. C., Elion-Mboussa, A., Hoover, A., Yu, A. & Fredlund, P., Sep 2005, In : International Journal of Impotence Research. 17, 5, p. 455-461 7 p.

Research output: Contribution to journalArticle

Myalgia
Back Pain
Incidence
Placebos
Type 5 Cyclic Nucleotide Phosphodiesterases
1 Citation (Scopus)

Clinical PET/CT: A win or a loss for nuclear medicine?

Fletcher, J., 2005, In : Journal of Nuclear Medicine. 46, 3, p. 385 1 p.

Research output: Contribution to journalArticle

Nuclear Medicine
2002
18 Citations (Scopus)

Letters to the editor (multiple letters)

Fleischmann, K. E., Hunink, M. G. M., Kuntz, K. M., Douglas, P. S., Kymes, S., Fletcher, J., Shaw, L., Bruns, D. & Gillespie, K., 2002, In : Journal of Nuclear Cardiology. 9, 1, p. 133-134 2 p.

Research output: Contribution to journalArticle

False Negative Reactions
Stress Echocardiography
Single-Photon Emission-Computed Tomography
Exercise Test
Reproducibility of Results
23 Citations (Scopus)

PET scanning and the solitary pulmonary nodule

Fletcher, J., Jul 2002, In : Seminars in Thoracic and Cardiovascular Surgery. 14, 3, p. 268-274 7 p.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
Granuloma
Neoplasms
Thorax
Pulmonary Medicine
10 Citations (Scopus)

Thymoma and myotonic dystrophy: Successful treatment with chemotherapy and radiation: Case report and review of the literature

Kudva, G. C., Maliekel, K., Kim, H. J., Naunheim, K. S., Stolar, C., Fletcher, J. & Puri, S., 2002, In : Chest. 121, 6, p. 2061-2063 3 p.

Research output: Contribution to journalArticle

Myotonic Dystrophy
Thymoma
Radiation
Drug Therapy
Combined Modality Therapy
2000
17 Citations (Scopus)

Anatomy of a meta-analysis: A critical review of "Exercise echocardiography or exercise SPECT imaging? A meta-analysis of diagnostic test performance"

Kymes, S. M., Bruns, D. E., Shaw, L. J., Gillespie, K. N. & Fletcher, J., 2000, In : Journal of Nuclear Cardiology. 7, 6, p. 599-611 13 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Routine Diagnostic Tests
Echocardiography
Meta-Analysis
Anatomy
2 Citations (Scopus)

Demonstration of scrotal disease on bone scintigraphy

Martin, L. A., Amato, M. E. & Fletcher, J., 2000, In : Clinical Nuclear Medicine. 25, 12, p. 1017-1018 2 p.

Research output: Contribution to journalArticle

Bone Diseases
Radionuclide Imaging
Bone and Bones
Radioisotopes
194 Citations (Scopus)

Surveillance for recurrent head and neck cancer using positron emission tomography

Lowe, V. J., Boyd, J. H., Dunphy, F. R., Kim, H., Dunleavy, T., Collins, B. T., Martin, D., Stack, B. C., Hollenbeak, C. & Fletcher, J., Feb 2000, In : Journal of Clinical Oncology. 18, 3, p. 651-658 8 p.

Research output: Contribution to journalArticle

Head and Neck Neoplasms
Positron-Emission Tomography
Recurrence
Physical Examination
Therapeutics
1999
3 Citations (Scopus)

Exercise echocardiography vs exercise SPECT testing.

Kymes, S., Shaw, L. & Fletcher, J., Nov 3 1999, In : Journal of the American Medical Association. 282, 17

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Exercise Test
Coronary Disease
Echocardiography
17 Citations (Scopus)

Overexpression of MPS antigens by squamous cell carcinomas of the head and neck immunohistochemical and serological correlation with FDG positron emission tomography

Stack, B. C., Dalsaso, T. A., Lee, C., Lowe, V. J., Hamilton, P. D., Fletcher, J. & Fernandez-Pol, J. A., 1999, In : Anticancer Research. 19, 6 C, p. 5503-5510 8 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Antigens
Squamous Cell Carcinoma
Tumor Biomarkers
Neoplasms
31 Citations (Scopus)

Primary and recurrent early stage laryngeal cancer: Preliminary results of 2-[fluorine 18]fluoro-2-deoxy-D-glucose pet imaging

Lowe, V. J., Kim, H., Boyd, J. H., Elsenbeis, J. F., Dunphy, F. R. & Fletcher, J., Sep 1999, In : Radiology. 212, 3, p. 799-802 4 p.

Research output: Contribution to journalArticle

Laryngeal Neoplasms
Fluorine
Pets
Deoxyglucose
Positron-Emission Tomography
1998
2 Citations (Scopus)

Design of prospective clinical trials for assessment of PET

Fletcher, J., Adams, E., Flynn, K. & Papatheofanis, F. J., 1998, In : Clinical Positron Imaging (Netherlands). 1, 3, p. 201-211 11 p.

Research output: Contribution to journalArticle

Decision Making
Clinical Trials
Evidence-Based Medicine
Diagnostic Imaging
Routine Diagnostic Tests
60 Citations (Scopus)

Procedure guideline for diagnosis of renovascular hypertension

Taylor A.T., J., Fletcher, J., Nally J.V., J., Blaufox, M. D., Dubovsky, E. V., Fine, E. J., Kahn, D., Morton, K. A., Russell, C. D., Sfakianakis, G. N., Aurell, M., Dondi, M., Fommei, E., Geyskes, G., Granerus, G. & Oei, H. Y., 1998, In : Journal of Nuclear Medicine. 39, 7, p. 1297-1302 6 p.

Research output: Contribution to journalArticle

Radioisotope Renography
Renovascular Hypertension
Renal Artery Obstruction
Radiopharmaceuticals
Preschool Children

Prospective investigation of positron emission tomography in lung nodules

Lowe, V. J., Fletcher, J., Gobar, L., Lawson, M., Kirchner, P., Valk, P., Karis, J., Hubner, K., Delbeke, D., Heiberg, E. V., Patz, E. F. & Coleman, R. E., 1998, In : Pneumologie. 52, 7, p. 432 1 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Lung
476 Citations (Scopus)

Prospective investigation of positron emission tomography in lung nodules

Lowe, V. J., Fletcher, J., Gobar, L., Lawson, M., Kirchner, P., Valk, P., Karis, J., Hubner, K., Delbeke, D., Heiberg, E. V., Patz, E. F. & Coleman, R. E., Mar 1998, In : Journal of Clinical Oncology. 16, 3, p. 1075-1084 10 p.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
Positron-Emission Tomography
Lung
Fluorine
Deoxyglucose
1997
137 Citations (Scopus)

Evaluation of chemotherapy response in patients with advanced head and neck cancer using [F-18]fluorodeoxyglucose positron emission tomography

Lowe, V. J., Dunphy, F. R., Varvares, M., Kim, H., Wittry, M., Dunphy, C. H., Dunleavy, T., McDonough, E., Minster, J., Fletcher, J. & Boyd, J. H., Dec 1997, In : Head and Neck. 19, 8, p. 666-674 9 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Head and Neck Neoplasms
Positron-Emission Tomography
Tomography
Drug Therapy
28 Citations (Scopus)

Expression of metallopanstimulin and oncogenesis in human prostatic carcinoma

Fernandez-Pol, J. A., Fletcher, J., Hamilton, P. D. & Klos, D. J., 1997, In : Anticancer Research. 17, 3 A, p. 1519-1530 12 p.

Research output: Contribution to journalArticle

Carcinogenesis
Carcinoma
Antigens
Neoplasms
Prostatic Neoplasms
21 Citations (Scopus)

Metallopanstimulin is overexpressed in a patient with colonic carcinoma

Ganger, D. R., Hamilton, P. D., Fletcher, J. & Albert Fernandez-Pol, J., 1997, In : Anticancer Research. 17, 3 C, p. 1993-1999 7 p.

Research output: Contribution to journalArticle

Mucous Membrane
Carcinoma
Ascending Colon
Proteins
Zinc Fingers
62 Citations (Scopus)

Procedure guideline for gallium scintigraphy in the evaluation of malignant disease

Bartold, S. P., Donohoe, K. J., Fletcher, J., Haynie, T. P., Henkin, R. E., Silberstein, E. B., Royal, H. D., Van Den Abbeele, A. & Wong, O., Jun 1997, In : Journal of Nuclear Medicine. 38, 6, p. 990-994 5 p.

Research output: Contribution to journalArticle

Gallium Radioisotopes
Radiation Dosage
Gallium
Preschool Children
Single-Photon Emission-Computed Tomography
1996
137 Citations (Scopus)

Consensus report on ACE inhibitor renography for detecting renovascular hypertension

Taylor, A., Nally, J., Aurell, M., Blaufox, D., Dondi, M., Dubovsky, E., Fine, E., Fommei, E., Geyskes, G., Granerus, G., Kahn, D., Morton, K., Oei, H. Y., Russell, C., Sfakianakis, G. & Fletcher, J., Nov 1996, In : Journal of Nuclear Medicine. 37, 11, p. 1876-1882 7 p.

Research output: Contribution to journalArticle

Iodine Radioisotopes
Iodohippuric Acid
Technetium Tc 99m Mertiatide
Technetium Tc 99m Pentetate
Radioisotope Renography
6 Citations (Scopus)

Guidelines for Guideline Development

Royal, H., Pierson, R., Fletcher, J., Dillehay, G. & Smith, W., 1996, In : Journal of Nuclear Medicine. 37, 5, p. 878-881 4 p.

Research output: Contribution to journalArticle

Medical Societies
Nuclear Medicine
Practice Guidelines
Primary Health Care
Guidelines
3 Citations (Scopus)

Is PET ready for prime time?

Fletcher, J. & Lowe, V. J., Jun 1996, In : Journal of Nuclear Medicine. 37, 6, p. 948-949 2 p.

Research output: Contribution to journalArticle

Emission-Computed Tomography
Health Insurance Reimbursement
X Ray Computed Tomography
Lung Neoplasms
Costs and Cost Analysis
20 Citations (Scopus)

Quantitative technetium-99m dimercaptosuccinic acid renal scanning in children

Goodgold, H. M., Fletcher, J. & Steinhardt, G. F., Mar 1996, In : Urology. 47, 3, p. 405-408 4 p.

Research output: Contribution to journalArticle

Technetium Tc 99m Dimercaptosuccinic Acid
Succimer
Kidney
Creatinine
Radionuclide Imaging
1994
33 Citations (Scopus)

Analysis of radiocontrast-induced nephropathy by dual-labeled radionuclide clearance

Albert, S. G., Shapiro, M. J., Brown, W. W., Goodgold, H., Zuckerman, D., Durham, R., Kern, M., Fletcher, J., Wolverson, M., Plummer, E. S. & Baue, A. E., 1994, In : Investigative Radiology. 29, 6, p. 618-623 6 p.

Research output: Contribution to journalArticle

Radioisotopes
Kidney
Contrast Media
Creatinine
Adenosine Triphosphate