James Fletcher

  • 4486 Citations
  • 22 h-Index
1969 …2019
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Publications 1969 2019

  • 4486 Citations
  • 22 h-Index
  • 104 Article
  • 3 Chapter
  • 2 Conference contribution
Article

[68Ga]Ga-P16-093 as a PSMA-Targeted PET Radiopharmaceutical for Detection of Cancer: Initial Evaluation and Comparison with [68Ga]Ga-PSMA-11 in Prostate Cancer Patients Presenting with Biochemical Recurrence

Green, M., Hutchins, G., Bahler, C. D., Tann, M., Mathias, C. J., Territo, W., Sims, J., Polson, H., Alexoff, D., Eckelman, W. C., Kung, H. F. & Fletcher, J., Jan 1 2019, (Accepted/In press) In : Molecular Imaging and Biology.

Research output: Contribution to journalArticle

Radiopharmaceuticals
Positron-Emission Tomography
Prostatic Neoplasms
Recurrence
Radiometry
17 Citations (Scopus)

67Ga citrate distribution following whole body irradiation or chemotherapy

Fletcher, J., Herbig, F. K. & Donati, R. M., 1975, In : Radiology. 117, 3 I, p. 709-712 4 p.

Research output: Contribution to journalArticle

Gallium
Whole-Body Irradiation
Citric Acid
Drug Therapy
Mechlorethamine
4 Citations (Scopus)

A comparison of in-house and regionalized computerized tomography scanning: Clinical impact and cost

Elixhauser, A., Reker, D. M., Gillespie, K. N., Fletcher, J. & Wolinsky, F. D., 1990, In : Health Services Research. 25, 1 II, p. 177-196 20 p.

Research output: Contribution to journalArticle

Tomography
Costs and Cost Analysis
efficiency
costs
utilization
102 Citations (Scopus)

A comparison of the diagnostic accuracy of 18F-FDG PET and CT in the characterization of solitary pulmonary nodules

Fletcher, J., Kymes, S. M., Gould, M., Alazraki, N., Coleman, R. E., Lowe, V. J., Marn, C., Segall, G., Thet, L. A. & Lee, K., Feb 1 2008, In : Journal of Nuclear Medicine. 49, 2, p. 179-185 7 p.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
Fluorodeoxyglucose F18
Confidence Intervals
Veterans
Radiography
2 Citations (Scopus)

A homogeneity index (HI) for 201 thallium myocardial distribution in coronary artery disease (CAD)

Fletcher, J., Walter, K. E. & Witztum, K., 1977, In : The American Journal of Cardiology. 39, 2, p. 320 1 p.

Research output: Contribution to journalArticle

Thallium
Coronary Artery Disease
33 Citations (Scopus)

Analysis of radiocontrast-induced nephropathy by dual-labeled radionuclide clearance

Albert, S. G., Shapiro, M. J., Brown, W. W., Goodgold, H., Zuckerman, D., Durham, R., Kern, M., Fletcher, J., Wolverson, M., Plummer, E. S. & Baue, A. E., 1994, In : Investigative Radiology. 29, 6, p. 618-623 6 p.

Research output: Contribution to journalArticle

Radioisotopes
Kidney
Contrast Media
Creatinine
Adenosine Triphosphate
17 Citations (Scopus)

Anatomy of a meta-analysis: A critical review of "Exercise echocardiography or exercise SPECT imaging? A meta-analysis of diagnostic test performance"

Kymes, S. M., Bruns, D. E., Shaw, L. J., Gillespie, K. N. & Fletcher, J., 2000, In : Journal of Nuclear Cardiology. 7, 6, p. 599-611 13 p.

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Routine Diagnostic Tests
Echocardiography
Meta-Analysis
Anatomy
76 Citations (Scopus)

A Pilot Trial of Serial 18F-Fluorodeoxyglucose Positron Emission Tomography in Patients With Medically Inoperable Stage I Non-Small-Cell Lung Cancer Treated With Hypofractionated Stereotactic Body Radiotherapy

Henderson, M. A., Hoopes, D. J., Fletcher, J., Lin, P. F., Tann, M., Yiannoutsos, C., Williams, M. D., Fakiris, A. J., McGarry, R. C. & Timmerman, R. D., Mar 1 2010, In : International Journal of Radiation Oncology Biology Physics. 76, 3, p. 789-795 7 p.

Research output: Contribution to journalArticle

Radiosurgery
Fluorodeoxyglucose F18
Non-Small Cell Lung Carcinoma
Positron-Emission Tomography
lungs
4 Citations (Scopus)
Solitary Pulmonary Nodule
Positron-Emission Tomography
Smoking
Routine Diagnostic Tests
Health Policy

A three-part study to investigate the incidence and potential etiologies of tadalafil-associated back pain or myalgia

Seftel, A. D., Farber, J., Fletcher, J., Deeley, M. C., Elion-Mboussa, A., Hoover, A., Yu, A. & Fredlund, P., Apr 2006, In : Journal of Urology. 175, 4, p. 1450 1 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

A three-part study to investigate the incidence and potential etiologies of tadalafil-associated back pain or myalgia

Seftel, A. D., Farber, J., Fletcher, J., Deeley, M. C., Elion-Mboussa, A., Hoover, A., Yu, A. & Fredlund, P., Sep 2005, In : International Journal of Impotence Research. 17, 5, p. 455-461 7 p.

Research output: Contribution to journalArticle

Myalgia
Back Pain
Incidence
Placebos
Type 5 Cyclic Nucleotide Phosphodiesterases
9 Citations (Scopus)

Atrial pacing and thallium 201 scintigraphy: Combined use for diagnosis of coronary artery disease

Stratmann, H. G., Mark, A. L., Walter, K. E., Fletcher, J. & Williams, G. A., 1987, In : Angiology. 38, 11, p. 807-814 8 p.

Research output: Contribution to journalArticle

Thallium
Radionuclide Imaging
Coronary Artery Disease
Exercise Test
Perfusion Imaging
1 Citation (Scopus)

Bone marrow 99Tc(m) sulfur colloid distribution and marrow cellularity

Henry, R. E., Fletcher, J., George, E. A. & Donati, R. M., 1975, In : American Journal of the Medical Sciences. 270, 3, p. 419-425 7 p.

Research output: Contribution to journalArticle

Colloids
Sulfur
Bone Marrow
Cell Line
Hematopoiesis
5 Citations (Scopus)

Bone marrow scanning in Paget's disease

Fletcher, J., Butler, R. L., Henry, R. E., Solaric-George, E. & Donati, R. M., 1973, In : Journal of Nuclear Medicine. 14, 12, p. 928-939 12 p.

Research output: Contribution to journalArticle

Bone Marrow
Osteitis Deformans
Polyphosphates
Colloids
Sulfur
18 Citations (Scopus)

Brain Scans, Dexamethasone Therapy, and Brain Tumors

Fletcher, J., George, E. A., Henry, R. E. & Donati, R. M., Jun 23 1975, In : Journal of the American Medical Association. 232, 12, p. 1261-1263 3 p.

Research output: Contribution to journalArticle

Brain Neoplasms
Dexamethasone
Brain
Sodium Pertechnetate Tc 99m
Nervous System
15 Citations (Scopus)

Can FDG-PET be used to predict growth of stage I lung cancer?

Tann, M., Sandrasegaran, K., Winer-Muram, H. T., Jennings, S. G., Welling, M. E. & Fletcher, J., Aug 2008, In : Clinical Radiology. 63, 8, p. 856-863 8 p.

Research output: Contribution to journalArticle

Positron-Emission Tomography
Lung Neoplasms
Glucose
Growth
Tomography
90 Citations (Scopus)

Cerebral blood flow changes during vagus nerve stimulation for depression

Conway, C. R., Sheline, Y. I., Chibnall, J. T., George, M. S., Fletcher, J. & Mintun, M. A., Mar 31 2006, In : Psychiatry Research - Neuroimaging. 146, 2, p. 179-184 6 p.

Research output: Contribution to journalArticle

Cerebrovascular Circulation
Vagus Nerve Stimulation
Depression
Regional Blood Flow
Treatment-Resistant Depressive Disorder
1 Citation (Scopus)

Clinical estimation of infarct size by 201Thallium perfusion scintigraphy and by creatine kinase-MB in early myocardial infarction

Fletcher, J., Rao, P. S., Witztum, K. F., Hamilton, W. P., Donati, R. M. & Mueller, H. S., 1980, In : Clinical Cardiology. 3, 2, p. 111-115 5 p.

Research output: Contribution to journalArticle

MB Form Creatine Kinase
Perfusion Imaging
Computer-Assisted Image Processing
Creatine Kinase
Infarction
1 Citation (Scopus)

Clinical PET/CT: A win or a loss for nuclear medicine?

Fletcher, J., 2005, In : Journal of Nuclear Medicine. 46, 3, p. 385 1 p.

Research output: Contribution to journalArticle

Nuclear Medicine

Comparison of left ventricular ejection fraction (LVEF) in man and dogs using first transit and ECG gated scintiangiography

Fletcher, J., Herbig, F. K. & Daly, J. L., 1975, In : Journal of Nuclear Medicine. 16, 6, p. 527-528 2 p.

Research output: Contribution to journalArticle

Stroke Volume
Electrocardiography
Dogs

Computerized tomography (CT), abdominal ultrasound (US), and Tc-99m pipida (PIP) imaging in intrahepatic and extrahepatic cholestasis

Perrillo, R. P., Joshi, S. N., George, E. A. & Fletcher, J., 1980, In : Gastroenterology. 78, 5 II, p. 1236 1 p.

Research output: Contribution to journalArticle

Extrahepatic Cholestasis
Intrahepatic Cholestasis
Tomography
22 Citations (Scopus)

Consensus development for producing diagnostic procedure guidelines: SPECT brain perfusion imaging with exametazime

Fletcher, J., Woolf, S. H. & Royal, H. D., 1994, In : Journal of Nuclear Medicine. 35, 12, p. 2003-2010 8 p.

Research output: Contribution to journalArticle

Perfusion Imaging
Single-Photon Emission-Computed Tomography
Neuroimaging
Consensus
Guidelines
138 Citations (Scopus)

Consensus report on ACE inhibitor renography for detecting renovascular hypertension

Taylor, A., Nally, J., Aurell, M., Blaufox, D., Dondi, M., Dubovsky, E., Fine, E., Fommei, E., Geyskes, G., Granerus, G., Kahn, D., Morton, K., Oei, H. Y., Russell, C., Sfakianakis, G. & Fletcher, J., Nov 1996, In : Journal of Nuclear Medicine. 37, 11, p. 1876-1882 7 p.

Research output: Contribution to journalArticle

Iodine Radioisotopes
Iodohippuric Acid
Technetium Tc 99m Mertiatide
Technetium Tc 99m Pentetate
Radioisotope Renography
1 Citation (Scopus)

Cost-benefit and cost-effectiveness analyses of magnetic resonance imaging.

Gillespie, K. N., Elixhauser, A., Reker, D. M., Fletcher, J. & Wolinsky, F. D., 1985, In : International Journal of Technology Assessment in Health Care. 1, 3, p. 537-550 14 p.

Research output: Contribution to journalArticle

Biomedical Technology Assessment
United States Department of Veterans Affairs
Cost-Benefit Analysis
Magnetic Resonance Spectroscopy
Magnetic Resonance Imaging
2 Citations (Scopus)

Demonstration of scrotal disease on bone scintigraphy

Martin, L. A., Amato, M. E. & Fletcher, J., 2000, In : Clinical Nuclear Medicine. 25, 12, p. 1017-1018 2 p.

Research output: Contribution to journalArticle

Bone Diseases
Radionuclide Imaging
Bone and Bones
Radioisotopes
2 Citations (Scopus)

Design of prospective clinical trials for assessment of PET

Fletcher, J., Adams, E., Flynn, K. & Papatheofanis, F. J., 1998, In : Clinical Positron Imaging (Netherlands). 1, 3, p. 201-211 11 p.

Research output: Contribution to journalArticle

Decision Making
Clinical Trials
Evidence-Based Medicine
Diagnostic Imaging
Routine Diagnostic Tests
10 Citations (Scopus)

Diagnosis of coronary artery disease with 201Tl. Computer analysis of myocardial perfusion images

Fletcher, J., Walter, K. E., Witztum, K. F., Daly, J. L., Herbig, F. K., Mueller, H. S. & Donati, R. M., 1978, In : Radiology. 128, 2, p. 423-427 5 p.

Research output: Contribution to journalArticle

Coronary Artery Disease
Electrocardiography
Perfusion
Exercise
Sensitivity and Specificity
2 Citations (Scopus)

Distribution and plasma binding of radiogallium following chemotherapy or radiation

Fletcher, J., Herbig, F. K. & Donati, R. M., 1974, In : Clinical Research. 22, 4

Research output: Contribution to journalArticle

Radiation
Drug Therapy
3 Citations (Scopus)

Effect of granulocytopenia, marrow suppressive drugs, and infection on marrow reticuloendothelial patterns

Henry, R. E., Fletcher, J., Solaric George, E. & Donati, R. M., 1974, In : Journal of Nuclear Medicine. 15, 5, p. 343-348 6 p.

Research output: Contribution to journalArticle

Agranulocytosis
Technetium
Colloids
Combination Drug Therapy
Hodgkin Disease
4 Citations (Scopus)

Effects of various respiratory maneuvers on the physiological response to angular acceleration.

Lipana, J. G., Fletcher, J., Brown, W. & Cohen, G., Sep 1969, In : Aerospace Medicine. 40, 9, p. 976-980 5 p.

Research output: Contribution to journalArticle

Cardiovascular Physiological Phenomena
Aerospace Medicine
Valsalva Maneuver
Telemetry
Respiration
7 Citations (Scopus)

Erythropoiesis and hyperoxia

Fletcher, J., Gallagher, N. I., Warnecke, M. A. & Donati, R. M., 1973, In : Proceedings of the Society for Experimental Biology and Medicine. 144, 2, p. 569-574 6 p.

Research output: Contribution to journalArticle

Hyperoxia
Erythropoiesis
Oxygen
Erythropoietin
Animals
9 Citations (Scopus)

Erythropoiesis in hypothyroidism

Donati, R. M., Fletcher, J., Warnecke, M. A. & Gallagher, N. I., 1973, In : Proceedings of the Society for Experimental Biology and Medicine. 144, 1, p. 78-82 5 p.

Research output: Contribution to journalArticle

Erythropoiesis
Triiodothyronine
Erythropoietin
Hypothyroidism
Rats
9 Citations (Scopus)

Estimation of radiation dosimetry for 68Ga-HBED-CC (PSMA-11) in patients with suspected recurrence of prostate cancer

Green, M., Eitel, J. A., Fletcher, J., Mathias, C. J., Tann, M. A., Territo, W., Polson, H., Hutchins, G., Gardner, T. & Koch, M., Mar 1 2017, In : Nuclear Medicine and Biology. 46, p. 32-35 4 p.

Research output: Contribution to journalArticle

Radiometry
Prostatic Neoplasms
Recurrence
Pelvis
Injections
7 Citations (Scopus)

Evaluation of <sup>11</sup>C-Acetate and <sup>18</sup> F-FDG PET/CT in mouse multidrug resistance gene-2 deficient mouse model of hepatocellular carcinoma

Territo, P., Maluccio, M., Riley, A. A., McCarthy, B. P., Fletcher, J., Tann, M., Saxena, R. & Skill, N., May 16 2015, In : BMC Medical Imaging. 15, 1, 15.

Research output: Contribution to journalArticle

MDR Genes
Hepatocellular Carcinoma
Multiple Drug Resistance
Liver
carbon-11 acetate
13 Citations (Scopus)

Evaluation of 99mTc pyrophosphate as a bone imaging agent

Fletcher, J., Solaric George, E., Henry, R. E. & Donati, R. M., 1973, In : Radiology. 109, 2, p. 467-469 3 p.

Research output: Contribution to journalArticle

Technetium Tc 99m Pyrophosphate
Bone and Bones
Neoplasm Metastasis
Carcinoma
Kidney
137 Citations (Scopus)

Evaluation of chemotherapy response in patients with advanced head and neck cancer using [F-18]fluorodeoxyglucose positron emission tomography

Lowe, V. J., Dunphy, F. R., Varvares, M., Kim, H., Wittry, M., Dunphy, C. H., Dunleavy, T., McDonough, E., Minster, J., Fletcher, J. & Boyd, J. H., Dec 1997, In : Head and Neck. 19, 8, p. 666-674 9 p.

Research output: Contribution to journalArticle

Fluorodeoxyglucose F18
Head and Neck Neoplasms
Positron-Emission Tomography
Tomography
Drug Therapy
357 Citations (Scopus)

Evaluation of patients with pulmonary nodules: When is it lung cancer? ACCP evidence-based clinical practice guidelines (2nd edition)

Gould, M. K., Fletcher, J., Iannettoni, M. D., Lynch, W. R., Midthun, D. E., Naidich, D. P. & Ost, D. E., Sep 2007, In : Chest. 132, 3 SUPPL.

Research output: Contribution to journalArticle

Solitary Pulmonary Nodule
Patient Preference
Evidence-Based Practice
Practice Guidelines
Lung Neoplasms
951 Citations (Scopus)

Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer

Timmerman, R., McGarry, R., Yiannoutsos, C., Papiez, L., Tudor, K., DeLuca, J., Ewing, M., Abdulrahman, R., DesRosiers, C., Williams, M. & Fletcher, J., Oct 20 2006, In : Journal of Clinical Oncology. 24, 30, p. 4833-4839 7 p.

Research output: Contribution to journalArticle

Lung Neoplasms
Radiotherapy
Neoplasms
Non-Small Cell Lung Carcinoma
Therapeutics
3 Citations (Scopus)

Exercise echocardiography vs exercise SPECT testing.

Kymes, S., Shaw, L. & Fletcher, J., Nov 3 1999, In : Journal of the American Medical Association. 282, 17

Research output: Contribution to journalArticle

Single-Photon Emission-Computed Tomography
Exercise Test
Coronary Disease
Echocardiography
3 Citations (Scopus)

Experience in production of 68Ga-DOTA-NOC for clinical use under an Expanded Access IND

Green, M., Mathias, C. J. & Fletcher, J., Oct 1 2016, In : Applied Radiation and Isotopes. 116, p. 63-68 6 p.

Research output: Contribution to journalArticle

generators
expiration
dosage
elution
synthesis
28 Citations (Scopus)

Expression of metallopanstimulin and oncogenesis in human prostatic carcinoma

Fernandez-Pol, J. A., Fletcher, J., Hamilton, P. D. & Klos, D. J., 1997, In : Anticancer Research. 17, 3 A, p. 1519-1530 12 p.

Research output: Contribution to journalArticle

Carcinogenesis
Carcinoma
Antigens
Neoplasms
Prostatic Neoplasms
130 Citations (Scopus)

FDG-PET and stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer

Hoopes, D. J., Tann, M., Fletcher, J., Forquer, J. A., Lin, P. F., Lo, S. S., Timmerman, R. D. & McGarry, R. C., May 2007, In : Lung Cancer. 56, 2, p. 229-234 6 p.

Research output: Contribution to journalArticle

Radiosurgery
Non-Small Cell Lung Carcinoma
Positron-Emission Tomography
Recurrence
Survival
6 Citations (Scopus)

Guidelines for Guideline Development

Royal, H., Pierson, R., Fletcher, J., Dillehay, G. & Smith, W., 1996, In : Journal of Nuclear Medicine. 37, 5, p. 878-881 4 p.

Research output: Contribution to journalArticle

Medical Societies
Nuclear Medicine
Practice Guidelines
Primary Health Care
Guidelines

Hepatic extraction of Tc-99m sulfur colloid (TSC) and hepatic transport of Tc-99m pipida (PIP) in normal subjects and acute viral hepatitis

Joshi, S. N., George, E. A., Fletcher, J. & Perrillo, R. P., 1980, In : Gastroenterology. 79, 5 II, p. 1029 1 p.

Research output: Contribution to journalArticle

Technetium Tc 99m Sulfur Colloid
Hepatitis
Liver
57 Citations (Scopus)

High signal intensity soft tissue masses on T1 weighted pulsing sequences

Sundaram, M., McGuire, M. H., Herbold, D. R., Beshany, S. E. & Fletcher, J., Jan 1987, In : Skeletal Radiology. 16, 1, p. 30-36 7 p.

Research output: Contribution to journalArticle

Histology
Fats
93 Citations (Scopus)

Imatinib mesylate for plexiform neurofibromas in patients with neurofibromatosis type 1: A phase 2 trial

Robertson, K., Nalepa, G., Yang, F. C., Bowers, D. C., Ho, C., Hutchins, G., Croop, J., Vik, T., Denne, S., Parada, L. F., Hingtgen, C. M., Walsh, L., Yu, M., Pradhan, K., Edwards-Brown, M. K., Cohen, M. D., Fletcher, J., Travers, J., Staser, K. W., Lee, M. W. & 5 others, Sherman, M. R., Davis, C. J., Miller, L. C., Ingram, D. & Clapp, D., Dec 2012, In : The Lancet Oncology. 13, 12, p. 1218-1224 7 p.

Research output: Contribution to journalArticle

Plexiform Neurofibroma
Neurofibromatosis 1
Imatinib Mesylate
Neoplasms
Chemoradiotherapy
Mathematical Computing
Computer Simulation
Software
3 Citations (Scopus)

Is PET ready for prime time?

Fletcher, J. & Lowe, V. J., Jun 1996, In : Journal of Nuclear Medicine. 37, 6, p. 948-949 2 p.

Research output: Contribution to journalArticle

Emission-Computed Tomography
Health Insurance Reimbursement
X Ray Computed Tomography
Lung Neoplasms
Costs and Cost Analysis
18 Citations (Scopus)

Letters to the editor (multiple letters)

Fleischmann, K. E., Hunink, M. G. M., Kuntz, K. M., Douglas, P. S., Kymes, S., Fletcher, J., Shaw, L., Bruns, D. & Gillespie, K., 2002, In : Journal of Nuclear Cardiology. 9, 1, p. 133-134 2 p.

Research output: Contribution to journalArticle

False Negative Reactions
Stress Echocardiography
Single-Photon Emission-Computed Tomography
Exercise Test
Reproducibility of Results