Jamie Renbarger

  • 842 Citations
  • 15 h-Index
20022021
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Publications 2002 2019

  • 842 Citations
  • 15 h-Index
  • 43 Article
  • 2 Chapter
  • 1 Conference contribution
2019

Genetic Variants Associated With Vincristine-Induced Peripheral Neuropathy in Two Populations of Children With Acute Lymphoblastic Leukemia

Li, L., Sajdyk, T., Smith, E. M. L., Chang, C. W., Li, C., Ho, R. H., Hutchinson, R., Wells, E., Skiles, J. L., Winick, N., Martin, P. L. & Renbarger, J., Jan 1 2019, (Accepted/In press) In : Clinical Pharmacology and Therapeutics.

Research output: Contribution to journalArticle

Vincristine
Peripheral Nervous System Diseases
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Population
Single Nucleotide Polymorphism
1 Citation (Scopus)

Integration of genomic copy number variations and chemotherapy-response biomarkers in pediatric sarcoma

Cheng, L., Pandya, P. H., Liu, E., Chandra, P., Wang, L., Murray, M. E., Carter, J., Ferguson, M., Saadatzadeh, M. R., Bijangi-Visheshsaraei, K., Marshall, M., Li, L., Pollok, K. & Renbarger, J., Jan 31 2019, In : BMC Medical Genomics. 12, 23.

Research output: Contribution to journalArticle

Sarcoma
Biomarkers
Pediatrics
Drug Therapy
Ewing's Sarcoma
2018

CYP3A5 genotype and its impact on vincristine pharmacokinetics and development of neuropathy in Kenyan children with cancer

Skiles, J. L., Chiang, C. W., Li, C. H., Martin, S., Smith, E. L., Olbara, G., Jones, D. R., Vik, T., Mostert, S., Abbink, F., Kaspers, G. J., Li, L., Njuguna, F., Sajdyk, T. J. & Renbarger, J., Mar 1 2018, In : Pediatric Blood and Cancer. 65, 3, e26854.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Vincristine
Pharmacokinetics
Genotype
Peripheral Nervous System Diseases
2017
1 Citation (Scopus)

Glutathione-S-transferase P1 may predispose children to a decline in pulmonary function after stem cell transplant

Stark, J., Renbarger, J., Slaven, J., Yu, Z., Then, J., Skiles, J. & Davis, S., 2017, (Accepted/In press) In : Pediatric Pulmonology.

Research output: Contribution to journalArticle

Glutathione Transferase
Stem Cells
Transplants
Lung
Single Nucleotide Polymorphism
4 Citations (Scopus)

IODNE: An integrated optimization method for identifying the deregulated subnetwork for precision medicine in cancer

Mounika Inavolu, S., Renbarger, J., Radovich, M., Vasudevaraja, V., Kinnebrew, G. H., Zhang, S. & Cheng, L., Mar 1 2017, In : CPT: Pharmacometrics and Systems Pharmacology. 6, 3, p. 168-176 9 p.

Research output: Contribution to journalArticle

Precision Medicine
Breast Cancer
Medicine
Optimization Methods
Cancer

Low serum albumin levels prior to pediatric allogeneic HCT are associated with increased need for critical care interventions and increased 6-month mortality

Teagarden, A. M., Skiles, J. L., Beardsley, A. L., Hobson, M. J., Moser, E. A. S., Renbarger, J. & Rowan, C. M., Sep 1 2017, In : Pediatric Transplantation. 21, 6, e13016.

Research output: Contribution to journalArticle

Critical Care
Serum Albumin
Hypoalbuminemia
Pediatrics
Mortality
1 Citation (Scopus)

PMTDS: a computational method based on genetic interaction networks for Precision Medicine Target-Drug Selection in cancer

Vasudevaraja, V., Renbarger, J., Shah, R. G., Kinnebrew, G., Korc, M., Wang, L., Huo, Y., Liu, E., Li, L. & Cheng, L., Dec 1 2017, In : Quantitative Biology. 5, 4, p. 380-394 15 p.

Research output: Contribution to journalArticle

Precision Medicine
Computational methods
Computational Methods
Medicine
Cancer

Use of Precision Medicine Molecular Profiling of Baseline Tumor Specimen May Not Benefit Outcomes in Children With Relapsed or Refractory Pediatric Sarcomas

Carter, J., Cheng, L., Zucker, J., Marshall, M., Pollok, K., Murray, M., Li, L. & Renbarger, J., Mar 1 2017, In : Clinical Pharmacology and Therapeutics. 101, 3, p. 328-330 3 p.

Research output: Contribution to journalArticle

Precision Medicine
Sarcoma
Pediatrics
Neoplasms
3 Citations (Scopus)

Weight gain and supplemental O2: Risk factors during the hematopoietic cell transplant admission in pediatric patients

Rowan, C. M., Nitu, M., Moser, E. A. S., Swigonski, N. & Renbarger, J., Nov 1 2017, In : Pediatric Blood and Cancer. 64, 11, e26561.

Research output: Contribution to journalArticle

Respiratory Insufficiency
Weight Gain
Pediatrics
Transplants
Intubation
2016
3 Citations (Scopus)

Hypoxia-inducible factor-1α regulates CD55 in airway epithelium

Pandya, P. H., Fisher, A. J., Mickler, E. A., Temm, C. J., Lipking, K. P., Gracon, A., Rothhaar, K., Sandusky, G., Murray, M., Pollok, K., Renbarger, J., Blum, J., Lahm, T. & Wilkes, D. S., Dec 1 2016, In : American Journal of Respiratory Cell and Molecular Biology. 55, 6, p. 889-898 10 p.

Research output: Contribution to journalArticle

Hypoxia-Inducible Factor 1
Epithelium
Epithelial Cells
Complement Activation
Gene Silencing
1 Citation (Scopus)
Attention Deficit and Disruptive Behavior Disorders
Conduct Disorder
Single Nucleotide Polymorphism
Dopamine beta-Hydroxylase
Dopamine D2 Receptors
1 Citation (Scopus)

Pharmacokinetic Variability of Mycophenolic Acid in Pediatric and Adult Patients With Hematopoietic Stem Cell Transplantation

Zhang, D., Renbarger, J. & Chow, D. S. L., Nov 1 2016, In : Journal of Clinical Pharmacology. p. 1378-1386 9 p.

Research output: Contribution to journalArticle

Mycophenolic Acid
Hematopoietic Stem Cell Transplantation
Pharmacokinetics
Pediatrics
Glucuronides
3 Citations (Scopus)
Precision Medicine
Nursing
Nurses
Attention Deficit and Disruptive Behavior Disorders
Nurse's Role
2 Citations (Scopus)

Simultaneous quantification of mycophenolic acid and its glucuronide metabolites in human plasma by an UPLC–MS/MS assay

Zhang, D., Chow, D. S. L. & Renbarger, J., Oct 1 2016, In : Biomedical Chromatography. 30, 10, p. 1648-1655 8 p.

Research output: Contribution to journalArticle

Plasma (human)
Metabolites
Mycophenolic Acid
Edetic Acid
Assays
15 Citations (Scopus)

The Immune System in Cancer Pathogenesis: Potential Therapeutic Approaches

Pandya, P. H., Murray, M. E., Pollok, K. & Renbarger, J., 2016, In : Journal of Immunology Research. 2016, 4273943.

Research output: Contribution to journalArticle

Immune System
Neoplasms
Precision Medicine
Therapeutics
Biomarkers
2015
19 Citations (Scopus)

Biomarkers for Diagnosis and Prognosis of Sinusoidal Obstruction Syndrome after Hematopoietic Cell Transplantation

Akil, A., Zhang, Q., Mumaw, C. L., Raiker, N., Yu, J., Velez de Mendizabal, N., Haneline, L., Robertson, K., Skiles, J., Diaz-Ricart, M., Carreras, E., Renbarger, J., Hanash, S., Bies, R. & Paczesny, S., Oct 1 2015, In : Biology of Blood and Marrow Transplantation. 21, 10, p. 1739-1745 7 p.

Research output: Contribution to journalArticle

Hepatic Veno-Occlusive Disease
Cell Transplantation
Biomarkers
Vascular Cell Adhesion Molecule-1
Hyaluronic Acid
53 Citations (Scopus)

Patterns and severity of vincristine-induced peripheral neuropathy in children with acute lymphoblastic leukemia

Lavoie Smith, E. M., Li, L., Chiang, C., Thomas, K., Hutchinson, R. J., Wells, E. M., Ho, R. H., Skiles, J., Chakraborty, A., Bridges, C. M. & Renbarger, J., Mar 1 2015, In : Journal of the Peripheral Nervous System. 20, 1, p. 37-46 10 p.

Research output: Contribution to journalArticle

Vincristine
Peripheral Nervous System Diseases
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
Combination Drug Therapy
2014
3 Citations (Scopus)

Opportunities and challenges of proteomics in pediatric patients: Circulating biomarkers after hematopoietic stem cell transplantation as a successful example

Paczesny, S., Duncan, C., Jacobsohn, D., Krance, R., Leung, K., Carpenter, P., Bollard, C., Renbarger, J. & Cooke, K., Dec 1 2014, In : Proteomics - Clinical Applications. 8, 11-12, p. 837-850 14 p.

Research output: Contribution to journalArticle

Pediatrics
Hematopoietic Stem Cell Transplantation
Biomarkers
Stem cells
Proteomics
3 Citations (Scopus)

Revitalizing personalized medicine: Respecting biomolecular complexities beyond gene expression

Jayachandran, D., Ramkrishna, U., Skiles, J., Renbarger, J. & Ramkrishna, D., 2014, In : CPT: Pharmacometrics and Systems Pharmacology. 3, 4, e110.

Research output: Contribution to journalArticle

Precision Medicine
Gene expression
Medicine
Gene Expression
Pharmacogenetics
2013

Early prediction of chemotherapy-induced toxicity: A pharmacometabonomics-based approach for personalized treatment

Jayachandran, D., Skiles, J., Renbarger, J. & Ramkrishna, D., 2013, Food, Pharmaceutical and Bioengineering Division 2013 - Core Programming Area at the 2013 AIChE Annual Meeting: Global Challenges for Engineering a Sustainable Future. AIChE, p. 604-605 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Chemotherapy
Toxicity
27 Citations (Scopus)

Measuring vincristine-induced peripheral neuropathy in children with acute lymphoblastic leukemia

Smith, E. M. L., Li, L., Hutchinson, R. J., Ho, R., Burnette, W. B., Wells, E., Bridges, C. & Renbarger, J., Sep 2013, In : Cancer Nursing. 36, 5

Research output: Contribution to journalArticle

Vincristine
Peripheral Nervous System Diseases
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
Pharmacokinetics
23 Citations (Scopus)

Nifedipine pharmacokinetics are influenced by CYP3A5 genotype when used as a preterm labor tocolytic

Haas, D., Quinney, S., Clay, J. M., Renbarger, J., Hebert, M. F., Clark, S., Umans, J. G. & Caritis, S. N., 2013, In : American Journal of Perinatology. 30, 4, p. 275-282 8 p.

Research output: Contribution to journalArticle

Tocolytic Agents
Cytochrome P-450 CYP3A
Premature Obstetric Labor
Nifedipine
Pharmacokinetics
7 Citations (Scopus)

Pharmacogenetic predictors of nausea and vomiting of pregnancy severity and response to antiemetic therapy: A pilot study

Lehmann, A. S., Renbarger, J., McCormick, C. L., Topletz, A. R., Rouse, C. & Haas, D., Jun 20 2013, In : BMC Pregnancy and Childbirth. 13, 132.

Research output: Contribution to journalArticle

Antiemetics
Pharmacogenetics
Nausea
Vomiting
Pregnancy
15 Citations (Scopus)

The relative contributions of CYP3A4 and CYP3A5 to the metabolism of vinorelbine

Topletz, A. R., Dennison, J. B., Barbuch, R. J., Hadden, C. E., Hall, S. D. & Renbarger, J., Sep 2013, In : Drug Metabolism and Disposition. 41, 9, p. 1651-1661 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Liver Microsomes
Vinca Alkaloids
vinorelbine
Cytochromes b5
35 Citations (Scopus)

The tumor suppressor CDKN3 controls mitosis

Nalepa, G., Barnholtz-Sloan, J., Enzor, R., Dey, D., He, Y., Gehlhausen, J. R., Lehmann, A. S., Park, S. J., Yang, Y., Yang, X., Chen, S., Guan, X., Chen, Y., Renbarger, J., Yang, F. C., Parada, L. F. & Clapp, D., Jun 2013, In : Journal of Cell Biology. 201, 7, p. 997-1012 16 p.

Research output: Contribution to journalArticle

Mitosis
Phosphoric Monoester Hydrolases
Centrosome
Neoplasms
Kinetochores
2012
12 Citations (Scopus)

A pilot study of the impact of genotype on nifedipine pharmacokinetics when used as a tocolytic

Haas, D., Quinney, S., McCormick, C. L., Jones, D. R. & Renbarger, J., Apr 2012, In : Journal of Maternal-Fetal and Neonatal Medicine. 25, 4, p. 419-423 5 p.

Research output: Contribution to journalArticle

Tocolytic Agents
Nifedipine
Pharmacokinetics
Genotype
Cytochrome P-450 CYP3A

Pharmacogenetics of obstetric therapeutics

Haas, D. & Renbarger, J., Jan 1 2012, Principles of Pharmacogenetics and Pharmacogenomics. Cambridge University Press, p. 202-216 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Obstetrics
Premature Obstetric Labor
Pharmacogenetics
Drug therapy
Premature Birth
61 Citations (Scopus)

Risk factors for cisplatin-associated ototoxicity in pediatric oncology patients

Yancey, A., Harris, M. S., Egbelakin, A., Gilbert, J., Pisoni, D. & Renbarger, J., Jul 15 2012, In : Pediatric Blood and Cancer. 59, 1, p. 144-148 5 p.

Research output: Contribution to journalArticle

Cisplatin
Pediatrics
Hearing Loss
Hearing
Hepatoblastoma
2011
7 Citations (Scopus)
Cheek
Fetal Blood
Newborn Infant
DNA
Premature Obstetric Labor
26 Citations (Scopus)

Dactinomycin and vincristine toxicity in the treatment of childhood cancer: A retrospective study from the Children's Oncology Group

Langholz, B., Skolnik, J. M., Barrett, J. S., Renbarger, J., Seibel, N. L., Zajicek, A. & Arndt, C. A. S., Aug 2011, In : Pediatric Blood and Cancer. 57, 2, p. 252-257 6 p.

Research output: Contribution to journalArticle

Dactinomycin
Vincristine
Retrospective Studies
Neoplasms
Body Size
5 Citations (Scopus)

Human breast milk as a source of DNA for amplification

Haas, D., Daum, M., Skaar, T., Philips, S., Miracle, D. & Renbarger, J., Apr 2011, In : Journal of Clinical Pharmacology. 51, 4, p. 616-619 4 p.

Research output: Contribution to journalArticle

Pharmacogenetics
Human Milk
Polymerase Chain Reaction
DNA
100 Citations (Scopus)

Increased risk of vincristine neurotoxicity associated with low CYP3A5 expression genotype in children with acute lymphoblastic leukemia

Egbelakin, A., Ferguson, M. J., MacGill, E. A., Lehmann, A. S., Topletz, A. R., Quinney, S., Li, L., McCammack, K. C., Hall, S. D. & Renbarger, J., Mar 2011, In : Pediatric Blood and Cancer. 56, 3, p. 361-367 7 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Vincristine
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Genotype
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma

Pharmacokinetic studies in pregnant women

Renbarger, J. & Haas, D., 2011, Pharmacokinetics in Drug Development. Springer US, Vol. 3. p. 195-209 15 p.

Research output: Chapter in Book/Report/Conference proceedingChapter

Pregnant Women
Pharmacokinetics
Pregnancy
Pharmaceutical Preparations
10 Citations (Scopus)

Pharmacotherapy and pregnancy: Highlights from the third international conference for individualized pharmacotherapy in pregnancy

Haas, D., Gallauresi, B., Shields, K., Zeitlin, D., Clark, S. M., Hebert, M. F., Ren, Z., Nallani, S. C., Meslin, E. M., Feibus, K. B., Koren, G., Goebel, W., Easterling, T., Denne, S., Flockhart, D. A. & Renbarger, J., Jun 2011, In : Clinical and Translational Science. 4, 3, p. 204-209 6 p.

Research output: Contribution to journalArticle

Drug therapy
Drug Therapy
Pregnancy
Obstetrics
Pharmaceutical Preparations
2009
47 Citations (Scopus)

Impact of body composition on pharmacokinetics of doxorubicin in children: A Glaser Pediatric Research Network study

Thompson, P. A., Rosner, G. L., Matthay, K. K., Moore, T. B., Bomgaars, L. R., Ellis, K. J., Renbarger, J. & Berg, S. L., Jul 2009, In : Cancer Chemotherapy and Pharmacology. 64, 2, p. 243-251 9 p.

Research output: Contribution to journalArticle

Pediatrics
Pharmacokinetics
Body Composition
Doxorubicin
Chemical analysis
3 Citations (Scopus)

Pharmacotherapy and pregnancy: Highlights from the first International Conference for Individualized Pharmacotherapy in Pregnancy.

Haas, D., Renbarger, J., Denne, S., Ahmed, M. S., Easterling, T., Feibus, K., Meslin, E. M., Koren, G., Zajicek, A., Snodgrass, W. R. & Flockhart, D. A., Feb 2009, In : Clinical and Translational Science. 2, 1, p. 11-14 4 p.

Research output: Contribution to journalArticle

Drug therapy
International cooperation
Antidepressive Agents
15 Citations (Scopus)

Pharmacotherapy and pregnancy: Highlights from the second international conference for individualized pharmacotherapy in pregnancy

Haas, D., Hebert, M. F., Soldin, O. P., Flockhart, D. A., Madadi, P., Nocon, J. J., Chambers, C. D., Hankins, G. D., Clark, S., Wisner, K. L., Li, L., Renbarger, J. & Learman, L. A., Dec 2009, In : Clinical and Translational Science. 2, 6, p. 439-443 5 p.

Research output: Contribution to journalArticle

Drug therapy
Drug Therapy
Pregnancy
Obstetrics
Cytochrome P-450 CYP2D6
2008
76 Citations (Scopus)

Effect of race on vincristine-associated neurotoxicity in pediatric acute lymphoblastic leukemia patients

Renbarger, J., McCammack, K. C., Rouse, C. E. & Hall, S. D., Apr 2008, In : Pediatric Blood and Cancer. 50, 4, p. 769-771 3 p.

Research output: Contribution to journalArticle

Vincristine
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Pediatrics
African Americans
Cytochrome P-450 CYP3A
7 Citations (Scopus)

Patient attitudes toward genotyping in an urban women's health clinic

Haas, D., Renbarger, J., Meslin, E. M., Drabiak, K. & Flockhart, D., Nov 2008, In : Obstetrics and Gynecology. 112, 5, p. 1023-1028 6 p.

Research output: Contribution to journalArticle

Urban Health
Women's Health
Needlestick Injuries
Saliva
DNA
17 Citations (Scopus)

Phase I clinical trial of intrathecal gemcitabine in patients with neoplastic meningitis

Bernardi, R. J., Bomgaars, L., Fox, E., Balis, F. M., Egorin, M. J., Lagattuta, T. F., Aikin, A., Whitcomb, P., Renbarger, J., Lieberman, F. S., Berg, S. L. & Blaney, S. M., Jul 2008, In : Cancer Chemotherapy and Pharmacology. 62, 2, p. 355-361 7 p.

Research output: Contribution to journalArticle

gemcitabine
Clinical Trials, Phase I
Meningitis
Pharmacokinetics
Deoxyuridine
24 Citations (Scopus)

Quantification of vincristine and its major metabolite in human plasma by high-performance liquid chromatography/tandem mass spectrometry

Dennison, J. B., Renbarger, J., Walterhouse, D. O., Jones, D. R. & Hall, S. D., Jun 2008, In : Therapeutic Drug Monitoring. 30, 3, p. 357-364 8 p.

Research output: Contribution to journalArticle

Plasma (human)
High performance liquid chromatography
Vincristine
Metabolites
Tandem Mass Spectrometry
7 Citations (Scopus)
Fetal Blood
Transplantation
Transplants
Granulocyte Colony-Stimulating Factor
Immunosuppressive Agents
2007
78 Citations (Scopus)

Effect of CYP3A5 expression on vincristine metabolism with human liver microsomes

Dennison, J. B., Jones, D. R., Renbarger, J. & Hall, S. D., May 2007, In : Journal of Pharmacology and Experimental Therapeutics. 321, 2, p. 553-563 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Liver Microsomes
Vincristine
Hydroxylation
2006
101 Citations (Scopus)

Selective metabolism of vincristine in vitro by CYP3A5

Dennison, J. B., Kulanthaivel, P., Barbuch, R. J., Renbarger, J., Ehlhardt, W. J. & Hall, S. D., 2006, In : Drug Metabolism and Disposition. 34, 8, p. 1317-1327 11 p.

Research output: Contribution to journalArticle

Cytochrome P-450 CYP3A
Vincristine
Metabolism
Genetic Polymorphisms
Metabolites
2004
10 Citations (Scopus)

Plasma and cerebrospinal fluid pharmacokinetics of SU5416 after intravenous administration in nonhuman primates

Renbarger, J., Aleksic, A., McGuffey, L., Dauser, R., Berg, S. & Blaney, S., Jan 2004, In : Cancer Chemotherapy and Pharmacology. 53, 1, p. 39-42 4 p.

Research output: Contribution to journalArticle

Cerebrospinal fluid
Pharmacokinetics
Intravenous Administration
Primates
Cerebrospinal Fluid
2002
16 Citations (Scopus)

Pneumonia in the immunocompromised pediatric cancer patient

Neville, K., Renbarger, J. & Dreyer, Z., 2002, In : Seminars in Respiratory Infections. 17, 1, p. 21-32 12 p.

Research output: Contribution to journalArticle

Pneumonia
Pediatrics
Pneumocystis carinii
Neoplasms
Fungi