Janice Blum

  • 10992 Citations
  • 44 h-Index
1980 …2019

Research output per year

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Publications

Article

Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes

Vecchio, F., Lo Buono, N., Stabilini, A., Nigi, L., Dufort, M. J., Geyer, S., Rancoita, P. M., Cugnata, F., Mandelli, A., Valle, A., Leete, P., Mancarella, F., Linsley, P. S., Krogvold, L., Herold, K. C., Larsson, H. E., Richardson, S. J., Morgan, N. G., Dahl-Jørgensen, K., Sebastiani, G. & 82 others, Dotta, F., Bosi, E., Bianconi, E., Bonfanti, R., Bonura, C., De Pellegrin, M., Frontino, G., Grogan, P., Laurenzi, A., Meschi, F., Ragogna, F., Rigamonti, A., Greenbaum, C. J., Atkinson, M., Baidal, D., Becker, D., Bingley, P., Buckner, J., Clements, M., Colman, P., DiMeglio, L., Gitelman, S., Goland, R., Gottlieb, P., Knip, M., Krischer, J., Lernmark, A., Moore, W., Moran, A., Muir, A., Palmer, J., Peakman, M., Philipson, L., Raskin, P., Redondo, M., Rodriguez, H., Russell, W., Spain, L., Schatz, D. A., Sosenko, J., Wentworth, J., Wherrett, D., Wilson, D., Winter, W., Ziegler, A., Anderson, M., Antinozzi, P., Benoist, C., Blum, J., Bourcier, K., Chase, P., Clare-Salzler, M., Clynes, R., Eisenbarth, G., Fathman, C. G., Grave, G., Hering, B., Insel, R., Kaufman, F., Kay, T., Leschek, E., Mahon, J., Marks, J. B., Nanto-Salonen, K., Nepom, G., Orban, T., Parkman, R., Pescovitz, M., Peyman, J., Pugliese, A., Roep, B., Roncarolo, M., Savage, P., Simell, O., Sherwin, R., Siegelman, M., Skyler, J. S., Steck, A., Thomas, J., Trucco, M., Wagner, J. & Battaglia, M., Sep 20 2018, In : JCI Insight. 3, 18, e122146.

Research output: Contribution to journalArticle

Open Access
16 Scopus citations

Absence of γ-interferon-inducible lysosomal thiol reductase in melanomas disrupts T cell recognition of select immunodominant epitopes

Haque, M. A., Li, P., Jackson, S. K., Zarour, H. M., Hawes, J. W., Phan, U. T., Maric, M., Cresswell, P. & Blum, J. S., May 20 2002, In : Journal of Experimental Medicine. 195, 10, p. 1267-1277 11 p.

Research output: Contribution to journalArticle

102 Scopus citations

A hybrid superoxide dismutase containing both functional iron and manganese

Clare, D. A., Blum, J. & Fridovich, I., Jun 28 1984, In : Journal of Biological Chemistry. 259, 9, p. 5932-5936 5 p.

Research output: Contribution to journalArticle

33 Scopus citations

Allergic Airway Disease in Mice Alters T and B Cell Responses during an Acute Respiratory Poxvirus Infection

Walline, C. C., Sehra, S., Fisher, A. J., Guindon, L. M., Kratzke, I. M., Montgomery, J. B., Lipking, K. P., Glosson, N. L., Benson, H. L., Sandusky, G. E., Wilkes, D. S., Brutkiewicz, R. R., Kaplan, M. H. & Blum, J. S., Apr 19 2013, In : PloS one. 8, 4, e62222.

Research output: Contribution to journalArticle

5 Scopus citations

Analysis of serum Hsp90 as a potential biomarker of β cell autoimmunity in type 1 diabetes

Ocaña, G. J., Sims, E. K., Watkins, R. A., Ragg, S., Mather, K. J., Oram, R. A., Mirmira, R. G., DiMeglio, L. A., Blum, J. S. & Evans-Molina, C., Jan 2019, In : PloS one. 14, 1, e0208456.

Research output: Contribution to journalArticle

2 Scopus citations

Antigen-presenting cells and the selection of immunodominant epitopes

Blum, J. S., Ma, C. & Kovats, S., Dec 29 1997, In : Critical reviews in immunology. 17, 5-6, p. 411-417 7 p.

Research output: Contribution to journalArticle

33 Scopus citations

Anti-type V collagen lymphocytes that express IL-17 and IL-23 induce rejection pathology in fresh and well-healed lung transplants

Yoshida, S., Haque, A., Mizobuchi, T., Iwata, T., Chiyo, M., Webb, T. J., Baldridge, L. A., Heidler, K. M., Cummings, O. W., Fujisawa, T., Blum, J. S., Brand, D. D. & Wilkes, D. S., Apr 2006, In : American Journal of Transplantation. 6, 4, p. 724-735 12 p.

Research output: Contribution to journalArticle

142 Scopus citations

Biotin labeling and quantitation of cell-surface proteins.

Turvy, D. N. & Blum, J. S., May 2001, In : Current protocols in immunology / edited by John E. Coligan ... [et al.]. Chapter 18, p. Unit 18.7

Research output: Contribution to journalArticle

9 Scopus citations

Cathepsin E: A Novel Target for Regulation by Class II Transactivator

Yee, C. S. K., Yao, Y., Li, P., Klemsz, M. J., Blum, J. S. & Chang, C. H., May 1 2004, In : Journal of Immunology. 172, 9, p. 5528-5534 7 p.

Research output: Contribution to journalArticle

Open Access
53 Scopus citations

CD4-Independent Infection of Astrocytes by Human Immunodeficiency Virus Type 1: Requirement for the Human Mannose Receptor

Liu, Y., Liu, H., Kim, B. O., Gattone, V. H., Li, J., Nath, A., Blum, J. & He, J. J., Apr 2004, In : Journal of virology. 78, 8, p. 4120-4133 14 p.

Research output: Contribution to journalArticle

153 Scopus citations

CD80 binding polyproline helical peptide inhibits T cell activation

Srinivasan, M., Lu, D., Eri, R., Brand, D. D., Haque, A. & Blum, J. S., Mar 18 2005, In : Journal of Biological Chemistry. 280, 11, p. 10149-10155 7 p.

Research output: Contribution to journalArticle

17 Scopus citations

CIITA-regulated plexin-A1 affects T-cell-dendritic cell interactions

Wong, A. W., Brickey, W. J., Taxman, D. J., van Deventer, H. W., Reed, W., Gao, J. X., Zheng, P., Liu, Y., Li, P., Blum, J. S., McKinnon, K. P. & Ting, J. P. Y., Sep 1 2003, In : Nature Immunology. 4, 9, p. 891-898 8 p.

Research output: Contribution to journalArticle

119 Scopus citations

Co-localization of molecules involved in antigen processing and presentation in an early endocytic compartment

Guagliardi, L. E., Koppelman, B., Blum, J. S., Marks, M. S., Cresswell, P. & Brodsky, F. M., Jan 1 1990, In : Nature. 343, 6254, p. 133-139 7 p.

Research output: Contribution to journalArticle

290 Scopus citations

Constitutive competition by self proteins for antigen presentation can be overcome by receptor-enhanced uptake

Lorenz, R. G., Blum, J. S. & Allen, P. M., 1990, In : Journal of Immunology. 144, 5, p. 1600-1606 7 p.

Research output: Contribution to journalArticle

37 Scopus citations

Coordinate defects in human histocompatibility leukocyte antigen class ii expression and antigen presentation in bare lymphocyte syndrome

Kovats, S., Drover, S., Marshall, W. L. H., Freed, D., Whiteley, P. E., Nepom, G. T. & Blum, J. S., Jun 1 1994, In : Journal of Experimental Medicine. 179, 6, p. 2017-2022 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Critical role of PPARγ in myeloid-derived suppressor cellstimulated cancer cell proliferation and metastasis

Zhao, T., Du, H., Blum, J. S. & Yan, C., 2016, In : Oncotarget. 7, 2, p. 1529-1543 15 p.

Research output: Contribution to journalArticle

19 Scopus citations

Cutting edge: NADPH oxidase modulates MHC class II antigen presentation by B cells

Crotzer, V. L., Matute, J. D., Arias, A. A., Zhao, H., Quilliam, L. A., Dinauer, M. C. & Blum, J. S., Oct 15 2012, In : Journal of Immunology. 189, 8, p. 3800-3804 5 p.

Research output: Contribution to journalArticle

31 Scopus citations

Cutting edge: Editing of recycling class II:Peptide complexes by HLA-DM

Pathak, S. S., Lich, J. D. & Blum, J. S., Jul 15 2001, In : Journal of Immunology. 167, 2, p. 632-635 4 p.

Research output: Contribution to journalArticle

Open Access
49 Scopus citations
Open Access
52 Scopus citations

Cutting edge: Rho activation and actin polarization are dependent on plexin-A1 in dendritic cells

Eun, S. Y., O'Connor, B. P., Wong, A. W., Van Deventer, H. W., Taxman, D. J., Reed, W., Li, P., Blum, J. S., McKinnon, K. P. & Ting, J. P. Y., Oct 1 2006, In : Journal of Immunology. 177, 7, p. 4271-4275 5 p.

Research output: Contribution to journalArticle

Open Access
24 Scopus citations

Cysteinylation of MHC class II ligands: Peptide endocytosis and reduction within APC influences T cell recognition

Haque, M. A., Hawes, J. W. & Blum, J. S., Apr 1 2001, In : Journal of Immunology. 166, 7, p. 4543-4551 9 p.

Research output: Contribution to journalArticle

Open Access
48 Scopus citations

Cytoplasmic processing is a prerequisite for presentation of an endogenous antigen by major histocompatibility complex class II proteins

Lich, J. D., Elliott, J. F. & Blum, J. S., May 1 2000, In : Journal of Experimental Medicine. 191, 9, p. 1513-1523 11 p.

Research output: Contribution to journalArticle

122 Scopus citations

Deficient antigen-presenting cell function in multiple genetic complementation groups of type II bare lymphocyte syndrome

Kovats, S., Nepom, G. T., Coleman, M., Nepom, B., Kwok, W. W. & Blum, J. S., Jul 1995, In : Journal of Clinical Investigation. 96, 1, p. 217-223 7 p.

Research output: Contribution to journalArticle

Open Access
29 Scopus citations

Delayed activation of the mannose receptor following synthesis: Requirement for exit from the endoplasmic reticulum

Pontow, S. E., Blum, J. S. & Stahl, P. D., Dec 14 1996, In : Journal of Biological Chemistry. 271, 48, p. 30736-30740 5 p.

Research output: Contribution to journalArticle

12 Scopus citations
22 Scopus citations

Differential expression of Smad7 transcripts identifies the CD4+CD45RChigh regulatory T cells that mediate type V collagen-induced tolerance to lung allografts

Mizobuchi, T., Yasufuku, K., Zheng, Y., Haque, M. A., Heidler, K. M., Woods, K., Smith, G. N., Cummings, O. W., Fujisawa, T., Blum, J. S. & Wilkes, D. S., Aug 1 2003, In : Journal of Immunology. 171, 3, p. 1140-1147 8 p.

Research output: Contribution to journalArticle

Open Access
60 Scopus citations

Diminished intracellular invariant chain expression after vaccinia virus infection

Wang, N., Weber, E. & Blum, J. S., Aug 1 2009, In : Journal of Immunology. 183, 3, p. 1542-1550 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Disruption of MHC class II-restricted antigen presentation by vaccinia virus

Li, P., Wang, N., Zhou, D., Yee, C. S. K., Chang, C. H., Brutkiewicz, R. R. & Blum, J. S., Nov 15 2005, In : Journal of Immunology. 175, 10, p. 6481-6488 8 p.

Research output: Contribution to journalArticle

Open Access
38 Scopus citations

Distinguishing between Mn-containing and Fe-containing superoxide dismutases in crude extracts of cells

Kirby, T., Blum, J., Kahane, I. & Fridovich, I., May 1980, In : Archives of Biochemistry and Biophysics. 201, 2, p. 551-555 5 p.

Research output: Contribution to journalArticle

58 Scopus citations

Diversifying biomedical training: A synergistic intervention

Gibau, G. S., Foertsch, J., Blum, J., Brutkiewicz, R., Queener, S., Roman, A., Rhodes, S., Sturek, M., Wilkes, D. & Broxmeyer, H., 2010, In : Journal of Women and Minorities in Science and Engineering. 16, 3, p. 215-235 21 p.

Research output: Contribution to journalArticle

10 Scopus citations

Donor lung derived myeloid and plasmacytoid dendritic cells differentially regulate T cell proliferation and cytokine production

Benson, H. L., Suzuki, H., Lott, J., Fisher, A. J., Walline, C., Heidler, K. M., Brutkiewicz, R., Blum, J. S. & Wilkes, D. S., Mar 20 2012, In : Respiratory Research. 13, 25.

Research output: Contribution to journalArticle

4 Scopus citations

Early activation of peripheral monocytes with hallmarks of M1 and M2 monocytic cells in excessive alcohol drinkers: A pilot study

Walline, C. C., Blum, J. S., Linton, T., Mangiacarne, D. & Liangpunsakul, S., Jan 1 2018, In : Journal of Investigative Medicine. 66, 5, p. 953-956 4 p.

Research output: Contribution to journalArticle

1 Scopus citations

Editing of an immunodominant epitope of glutamate decarboxylase by HLA-DM

Lich, J. D., Jayne, J. A., Zhou, D., Elliott, J. F. & Blum, J. S., Jul 15 2003, In : Journal of Immunology. 171, 2, p. 853-859 7 p.

Research output: Contribution to journalArticle

Open Access
37 Scopus citations

Editing of the HLA-DR-peptide repertoire by HLA-DM

Kropshofer, H., Vogt, A. B., Moldenhauer, G., Hammer, J., Blum, J. S. & Hämmerling, G. J., Nov 15 1996, In : EMBO Journal. 15, 22, p. 6144-6154 11 p.

Research output: Contribution to journalArticle

Open Access
230 Scopus citations

Effects of HIV protease inhibitor ritonavir on Akt-regulated cell proliferation in breast cancer

Srirangam, A., Mitra, R., Wang, M., Gorski, J. C., Badve, S., Baldridge, L. A., Hamilton, J., Kishimoto, H., Hawes, J., Li, L., Orschell, C. M., Srour, E. F., Blum, J. S., Donner, D., Sledge, G. W., Nakshatri, H. & Potter, D. A., Mar 15 2006, In : Clinical Cancer Research. 12, 6, p. 1883-1896 14 p.

Research output: Contribution to journalArticle

72 Scopus citations

Elevation of c-MYC disrupts HLA class II-mediated immune recognition of human B cell tumors

God, J. M., Cameron, C., Figueroa, J., Amria, S., Hossain, A., Kempkes, B., Bornkamm, G. W., Stuart, R. K., Blum, J. S. & Haque, A., Feb 15 2015, In : Journal of Immunology. 194, 4, p. 1434-1445 12 p.

Research output: Contribution to journalArticle

20 Scopus citations

Elevations in circulating methylated and unmethylated preproinsulin DNA in new-onset type 1 diabetes

Fisher, M. M., Watkins, R. A., Blum, J., Evans-Molina, C., Chalasani, N., Dimeglio, L. A., Mather, K. J., Tersey, S. A. & Mirmira, R. G., Nov 2015, In : Diabetes. 64, 11, p. 3867-3872 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Elevations in the fasting serum Proinsulin-to-C-peptide ratio precede the onset of type 1 diabetes

Sims, E. K., Chaudhry, Z., Watkins, R., Syed, F., Blum, J., Ouyang, F., Perkins, S. M., Mirmira, R. G., Sosenko, J., DiMeglio, L. A. & Evans-Molina, C., Sep 1 2016, In : Diabetes care. 39, 9, p. 1519-1526 8 p.

Research output: Contribution to journalArticle

38 Scopus citations

Endocytic recycling is required for the presentation of an exogenous peptide via MHC class II molecules

Pathak, S. S. & Blum, J. S., 2000, In : Traffic. 1, 7, p. 561-569 9 p.

Research output: Contribution to journalArticle

53 Scopus citations

Endosomal aspartic proteinases are required for invariant-chain processing

Marić, M. A., Taylor, M. D. & Blum, J. S., Mar 15 1994, In : Proceedings of the National Academy of Sciences of the United States of America. 91, 6, p. 2171-2175 5 p.

Research output: Contribution to journalArticle

Open Access
169 Scopus citations

Endosomal proteolysis precedes ricin A-chain toxicity in macrophages

Fiani, M. L., Blum, J. S. & Stahl, P. D., Jan 1 1993, In : Archives of Biochemistry and Biophysics. 307, 2, p. 225-230 6 p.

Research output: Contribution to journalArticle

21 Scopus citations
49 Scopus citations

Evidence for immune responses to a self-antigen in lung transplantation: Role of type V collagen-specific T cells in the pathogenesis of lung allograft rejection

Haque, M. A., Mizobuchi, T., Yasufuku, K., Fujisawa, T., Brutkiewicz, R. R., Zheng, Y., Woods, K., Smith, G. N., Cummings, O. W., Heidler, K. M., Blum, J. S. & Wilkes, D. S., Aug 1 2002, In : Journal of Immunology. 169, 3, p. 1542-1549 8 p.

Research output: Contribution to journalArticle

Open Access
142 Scopus citations
1 Scopus citations

HLA-DM negatively regulates HLA-DR4-restricted collagen pathogenic peptide presentation and T cell recognition

Amria, S., Hajiaghamohseni, L. M., Harbeson, C., Zhao, D., Goldstein, O., Blum, J. S. & Haque, A., Jul 2008, In : European Journal of Immunology. 38, 7, p. 1961-1970 10 p.

Research output: Contribution to journalArticle

21 Scopus citations

HSP90α and HSP90β isoforms selectively modulate MHC class II antigen presentation in B cells

Houlihan, J. L., Metzler, J. J. & Blum, J. S., Jun 15 2009, In : Journal of Immunology. 182, 12, p. 7451-7458 8 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hyper-responsive Toll-like receptor 7 and 9 activation in NADPH oxidase-deficient B lymphoblasts

Mcletchie, S., Volpp, B. D., Dinauer, M. C. & Blum, J. S., Dec 1 2015, In : Immunology. 146, 4, p. 595-606 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Hypoxia-inducible factor-1α regulates CD55 in airway epithelium

Pandya, P. H., Fisher, A. J., Mickler, E. A., Temm, C. J., Lipking, K. P., Gracon, A., Rothhaar, K., Sandusky, G. E., Murray, M., Pollok, K., Renbarger, J., Blum, J. S., Lahm, T. & Wilkes, D. S., Dec 2016, In : American journal of respiratory cell and molecular biology. 55, 6, p. 889-898 10 p.

Research output: Contribution to journalArticle

5 Scopus citations

Immunogenicity of Therapeutic Protein Aggregates

Moussa, E. M., Panchal, J. P., Moorthy, B. S., Blum, J., Joubert, M. K., Narhi, L. O. & Topp, E. M., Feb 1 2016, In : Journal of Pharmaceutical Sciences. 105, 2, p. 417-430 14 p.

Research output: Contribution to journalArticle

163 Scopus citations

Inactivation of glutathione peroxidase by superoxide radical

Blum, J. & Fridovich, I., Aug 1 1985, In : Archives of Biochemistry and Biophysics. 240, 2, p. 500-508 9 p.

Research output: Contribution to journalArticle

472 Scopus citations